Rolf Bjerkvig - Publications

The Department of biomedicine University of Bergen, Norway, Bergen, Hordaland, Norway 

215 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Guyon J, Fernandez-Moncada I, Larrieu CM, Bouchez CL, Pagano Zottola AC, Galvis J, Chouleur T, Burban A, Joseph K, Ravi VM, Espedal H, Røsland GV, Daher B, Barre A, Dartigues B, ... ... Bjerkvig R, et al. Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis. Embo Molecular Medicine. e15343. PMID 36278433 DOI: 10.15252/emmm.202115343  0.308
2021 Fabian C, Han M, Bjerkvig R, Niclou SP. Novel facets of glioma invasion. International Review of Cell and Molecular Biology. 360: 33-64. PMID 33962750 DOI: 10.1016/bs.ircmb.2020.08.001  0.402
2020 Lingasamy P, Tobi A, Kurm K, Kopanchuk S, Sudakov A, Salumäe M, Rätsep T, Asser T, Bjerkvig R, Teesalu T. Tumor-penetrating peptide for systemic targeting of Tenascin-C. Scientific Reports. 10: 5809. PMID 32242067 DOI: 10.1038/S41598-020-62760-Y  0.348
2019 Biedermann J, Preussler M, Conde M, Peitzsch M, Richter S, Wiedemuth R, Abou-El-Ardat K, Krüger A, Meinhardt M, Schackert G, Leenders WP, Herold-Mende C, Niclou SP, Bjerkvig R, Eisenhofer G, et al. Mutant IDH1 Differently Affects Redox State and Metabolism in Glial Cells of Normal and Tumor Origin. Cancers. 11. PMID 31888244 DOI: 10.3390/Cancers11122028  0.406
2019 Feng Z, Zhou W, Wang J, Qi Q, Han M, Kong Y, Hu Y, Zhang Y, Chen A, Huang B, Chen A, Zhang D, Li W, Zhang Q, Bjerkvig R, et al. Reduced expression of proteolipid protein 2 increases ER stress-induced apoptosis and autophagy in glioblastoma. Journal of Cellular and Molecular Medicine. PMID 31778016 DOI: 10.1111/Jcmm.14840  0.375
2019 Han M, Wang S, Yang N, Wang X, Zhao W, Saed HS, Daubon T, Huang B, Chen A, Li G, Miletic H, Thorsen F, Bjerkvig R, Li X, Wang J. Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma. Embo Molecular Medicine. e10924. PMID 31777202 DOI: 10.15252/Emmm.201910924  0.382
2019 Ji J, Ding K, Luo T, Xu R, Zhang X, Huang B, Chen A, Zhang D, Miletic H, Bjerkvig R, Thorsen F, Wang J, Li X. PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1. Oncogene. PMID 31605013 DOI: 10.1038/s41388-019-1050-9  0.307
2019 Aasen SN, Espedal H, Holte CF, Keunen O, Karlsen TV, Tenstad O, Maherally Z, Miletic H, Hoang T, Eikeland AV, Baghirov H, Olberg DE, Pilkington GJ, Sarkar G, Jenkins RB, ... ... Bjerkvig R, et al. Improved drug delivery to brain metastases by peptide-mediated permeabilization of the blood-brain barrier. Molecular Cancer Therapeutics. PMID 31467182 DOI: 10.1158/1535-7163.Mct-19-0160  0.352
2019 Dirkse A, Golebiewska A, Buder T, Nazarov PV, Muller A, Poovathingal S, Brons NHC, Leite S, Sauvageot N, Sarkisjan D, Seyfrid M, Fritah S, Stieber D, Michelucci A, Hertel F, ... ... Bjerkvig R, et al. Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment. Nature Communications. 10: 1787. PMID 30992437 DOI: 10.1038/S41467-019-09853-Z  0.464
2019 Hossain JA, Latif MA, Ystaas LAR, Ninzima S, Riecken K, Muller A, Azuaje F, Joseph JV, Talasila KM, Ghimire J, Fehse B, Bjerkvig R, Miletic H. Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma. Neuro-Oncology. PMID 30958558 DOI: 10.1093/Neuonc/Noz060  0.373
2019 Daubon T, Léon C, Clarke K, Andrique L, Salabert L, Darbo E, Pineau R, Guérit S, Maitre M, Dedieu S, Jeanne A, Bailly S, Feige JJ, Miletic H, Rossi M, ... ... Bjerkvig R, et al. Deciphering the complex role of thrombospondin-1 in glioblastoma development. Nature Communications. 10: 1146. PMID 30850588 DOI: 10.1038/S41467-019-08480-Y  0.378
2019 Mastrella G, Hou M, Li M, Stoecklein VM, Zdouc N, Volmar MNM, Miletic H, Reinhard S, Herold-Mende CC, Kleber S, Eisenhut K, Gargiulo G, Synowitz M, Vescovi AL, Harter PN, ... ... Bjerkvig R, et al. Targeting APLN/APLNR improves anti-angiogenic efficiency and blunts pro-invasive side effects of VEGFA/VEGFR2-blockade in glioblastoma. Cancer Research. PMID 30718358 DOI: 10.1158/0008-5472.Can-18-0881  0.339
2019 Han M, Wang S, Li X, Wang J, Bjerkvig R. Abstract LB-295: Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-295  0.443
2019 Kälin R, Mastrella G, Hou M, Li M, Stoecklein V, Zdouc N, Volmar M, Miletic H, Reinhard S, Herold-Mende C, Kleber S, Eisenhut K, Gargiulo G, Synowitz M, Vescovi A, ... ... Bjerkvig R, et al. ANGI-03. PHARMACOLOGICAL TARGETING OF APELIN/APLNR SIGNALING BLUNTS THERAPY RESISTANCE TO VEGFA/VEGFR2 ANTI-ANGIOGENIC TREATMENT IN GLIOBLASTOMA Neuro-Oncology. 21: vi30-vi30. DOI: 10.1093/Neuonc/Noz175.114  0.456
2019 Zhou W, Klink B, Dittmar G, Nazarov P, Garcia EM, Han M, Lunavat TR, Joesph JV, Saed HS, Bahador M, Wang J, Bjerkvig R. P11.57 A 3D brain organoid coculture system delineates the invasive cell components in glioblastoma Neuro-Oncology. 21: iii56-iii57. DOI: 10.1093/Neuonc/Noz126.203  0.423
2019 Golebiewska A, Dirkse A, Buder T, Yabo YA, Poovathingal S, Muller A, Nazarov PV, Herold-Mende C, Bjerkvig R, Skupin A, Deutsch A, Voss-Bohme A, Niclou SP. PL3.4 Intrinsic tumor plasticity in Glioblastoma allows for recreation of stem like-states and efficient tumor cell adaptation to new microenvironments Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz126.007  0.408
2018 Han M, Xu R, Wang S, Yang N, Ni S, Zhang Q, Xu Y, Zhang X, Zhang C, Wei Y, Ji J, Huang B, Zhang D, Chen A, Li W, ... Bjerkvig R, et al. Six-Transmembrane Epithelial Antigen of Prostate 3 Predicts Poor Prognosis and Promotes Glioblastoma Growth and Invasion. Neoplasia (New York, N.Y.). 20: 543-554. PMID 29730475 DOI: 10.1016/j.neo.2018.04.002  0.313
2018 Obad N, Espedal H, Jirik R, Sakariassen PO, Brekke Rygh C, Lund-Johansen M, Taxt T, Niclou SP, Bjerkvig R, Keunen O. Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 38: 1741-1753. PMID 28627960 DOI: 10.1177/0271678X17714656  0.305
2018 Zhou W, Klink B, Lunavat TR, Miletic H, Joesph JV, Han M, Bahador M, Wang J, Bjerkvig R. P04.87 Delineating the invasive component of human brain tumors using brain organoids Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy139.321  0.38
2017 Boyé K, Pujol N, D Alves I, Chen YP, Daubon T, Lee YZ, Dedieu S, Constantin M, Bello L, Rossi M, Bjerkvig R, Sue SC, Bikfalvi A, Billottet C. The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors. Nature Communications. 8: 1571. PMID 29146996 DOI: 10.1038/S41467-017-01686-Y  0.444
2017 Eskilsson E, Røsland GV, Solecki G, Wang Q, Harter PN, Graziani G, Verhaak RGW, Winkler F, Bjerkvig R, Miletic H. EGFR heterogeneity and implications for therapeutic intervention in glioblastoma. Neuro-Oncology. PMID 29040782 DOI: 10.1093/Neuonc/Nox191  0.324
2017 Zhang X, Xu R, Zhang C, Xu Y, Han M, Huang B, Chen A, Qiu C, Thorsen F, Prestegarden L, Bjerkvig R, Wang J, Li X. Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination. Journal of Experimental & Clinical Cancer Research : Cr. 36: 118. PMID 28870216 DOI: 10.1186/S13046-017-0588-Z  0.373
2017 Atzori MG, Tentori L, Ruffini F, Ceci C, Lisi L, Bonanno E, Scimeca M, Eskilsson E, Daubon T, Miletic H, Ricci Vitiani L, Pallini R, Navarra P, Bjerkvig R, D'Atri S, et al. The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells. Journal of Experimental & Clinical Cancer Research : Cr. 36: 106. PMID 28797294 DOI: 10.1186/S13046-017-0577-2  0.321
2017 Primon M, Huszthy PC, Motaln H, Talasila KM, Miletic H, Atai NA, Bjerkvig R, Lah Turnšek T. Cathepsin L silencing increases AsO toxicity in malignantly transformed pilocytic astrocytoma MPA58 cells by activating caspases 3/7. Experimental Cell Research. 356: 64-73. PMID 28412241 DOI: 10.1016/J.Yexcr.2017.04.013  0.368
2017 Zhu H, Leiss L, Yang N, Rygh CB, Mitra SS, Cheshier SH, Weissman IL, Huang B, Miletic H, Bjerkvig R, Enger PØ, Li X, Wang J. Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy. Oncotarget. PMID 28076333 DOI: 10.18632/Oncotarget.14553  0.363
2017 Aasen SN, Espedal H, Keunen O, Holte CF, Baghirov H, Bjerkvig R, Karlsen TV, Tenstad O, Olberg DE, Sarkar G, Jenkins RB, Thorsen F. Abstract 2865: The peptide transporter K16ApoE increases drug delivery across the blood brain barrier in an experimental animal model of melanoma brain metastases Cancer Research. 77: 2865-2865. DOI: 10.1158/1538-7445.Am2017-2865  0.334
2017 Hossain J, Ystaas L, Latif A, Joseph J, Talasila K, Ninzima S, Riecken K, Fehse B, Bjerkvig R, Miletic H. Exth-68. Recurrent Xenograft Tumors Upregulate Egfr After Lentiviral Vector Mediated Suicide Gene Therapy For Glioblastoma, But Are Resistant To Combinatorial Treatment With Erlotinib Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.360  0.349
2016 Talasila KM, Røsland GV, Hagland HR, Eskilsson E, Flønes IH, Fritah S, Azuaje F, Atai N, Harter PN, Mittelbronn M, Andersen M, Joseph JV, Hossain JA, Vallar L, Noorden CJ, ... ... Bjerkvig R, et al. The angiogenic switch leads to a metabolic shift in human glioblastoma. Neuro-Oncology. PMID 27591677 DOI: 10.1093/Neuonc/Now175  0.476
2016 Hossain JA, Ystaas LR, Mrdalj J, Välk K, Riecken K, Fehse B, Bjerkvig R, Grønli J, Miletic H. Lentiviral HSV-Tk.007 mediated suicide gene therapy is not toxic for normal brain cells. The Journal of Gene Medicine. PMID 27490042 DOI: 10.1002/Jgm.2895  0.377
2016 Eskilsson E, Rosland GV, Talasila KM, Knappskog S, Keunen O, Sottoriva A, Foerster S, Solecki G, Taxt T, Jirik R, Fritah S, Harter PN, Välk K, Al Hossain J, Joseph JV, ... ... Bjerkvig R, et al. EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation. Neuro-Oncology. PMID 27286795 DOI: 10.1093/Neuonc/Now113  0.366
2016 Bougnaud S, Golebiewska A, Oudin A, Keunen O, Harter PN, Mäder L, Azuaje F, Fritah S, Stieber D, Kaoma T, Vallar L, Brons NH, Daubon T, Miletic H, Sundstrøm T, ... ... Bjerkvig R, et al. Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma. Oncotarget. PMID 27049916 DOI: 10.18632/Oncotarget.7454  0.432
2016 Hulou MM, Cho CF, Chiocca EA, Bjerkvig R. Experimental therapies: gene therapies and oncolytic viruses. Handbook of Clinical Neurology. 134: 183-97. PMID 26948355 DOI: 10.1016/B978-0-12-802997-8.00011-6  0.325
2016 Podergajs N, Motaln H, Rajčević U, Verbovšek U, Koršič M, Obad N, Espedal H, Vittori M, Herold-Mende C, Miletic H, Bjerkvig R, Turnšek TL. Transmembrane protein CD9 is glioblastoma biomarker, relevant for maintenance of glioblastoma stem cells. Oncotarget. 7: 593-609. PMID 26573230 DOI: 10.18632/Oncotarget.5477  0.413
2016 Daubon T, Leon C, Clarke K, Poulet M, Miletic H, Falciani F, Bjerkvig R, Bikfalvi A. Abstract 4413: Thrombospondin-1 is a master regulator of glioblastoma vascularization and infiltration Cancer Research. 76: 4413-4413. DOI: 10.1158/1538-7445.Am2016-4413  0.505
2016 Säälik P, Hunt H, Tobi A, Willmore AA, Toome K, Sharma S, Kotamraju R, Bergers G, Bjerkvig R, Ruoslahti E, Teesalu T. Abstract 1343: P32-targeting TT1 peptide delivers nanoparticles to intracranial glioblastomas Cancer Research. 76: 1343-1343. DOI: 10.1158/1538-7445.Am2016-1343  0.352
2016 Hossain JA, Ystaas LR, Mrdalj J, Vaelk K, Riecken K, Fehse B, Bjerkvig R, Grønli J, Miletic H. 475. Effects of HSV-Tk Mediated Suicide Gene Therapy on Normal Brain Cells Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33284-1  0.432
2015 Tardito S, Oudin A, Ahmed SU, Fack F, Keunen O, Zheng L, Miletic H, Sakariassen PØ, Weinstock A, Wagner A, Lindsay SL, Hock AK, Barnett SC, Ruppin E, Mørkve SH, ... ... Bjerkvig R, et al. Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma. Nature Cell Biology. PMID 26595383 DOI: 10.1038/Ncb3272  0.353
2015 Huszthy PC, Sakariassen PØ, Espedal H, Brokstad KA, Bjerkvig R, Miletic H. Correction: Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression. Plos One. 10: e0140303. PMID 26431334 DOI: 10.1371/Journal.Pone.0140303  0.347
2015 Huszthy PC, Sakariassen PØ, Espedal H, Brokstad KA, Bjerkvig R, Miletic H. Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression. Plos One. 10: e0136089. PMID 26291724 DOI: 10.1371/Journal.Pone.0136089  0.423
2015 Demeure K, Fack F, Duriez E, Tiemann K, Bernard A, Golebiewska A, Bougnaud S, Bjerkvig R, Domon B, Niclou SP. Targeted Proteomics to Assess the Response to Anti-Angiogenic Treatment in Human Glioblastoma. Molecular & Cellular Proteomics : McP. PMID 26243272 DOI: 10.1074/Mcp.M115.052423  0.39
2015 Clarke K, Daubon T, Turan N, Soulet F, Mohd Zahari M, Ryan KR, Durant S, He S, Herbert J, Ankers J, Heath JK, Bjerkvig R, Bicknell R, Hotchin NA, Bikfalvi A, et al. Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer. Plos Genetics. 11: e1005325. PMID 26132659 DOI: 10.1371/Journal.Pgen.1005325  0.384
2015 Sanzey M, Abdul Rahim SA, Oudin A, Dirkse A, Kaoma T, Vallar L, Herold-Mende C, Bjerkvig R, Golebiewska A, Niclou SP. Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma. Plos One. 10: e0123544. PMID 25932951 DOI: 10.1371/Journal.Pone.0123544  0.461
2015 Sundstrøm T, Espedal H, Harter PN, Fasmer KE, Skaftnesmo KO, Horn S, Hodneland E, Mittelbronn M, Weide B, Beschorner R, Bender B, Rygh CB, Lund-Johansen M, Bjerkvig R, Thorsen F. Melanoma brain metastasis is independent of lactate dehydrogenase A expression. Neuro-Oncology. 17: 1374-85. PMID 25791837 DOI: 10.1093/Neuonc/Nov040  0.357
2015 Fack F, Espedal H, Keunen O, Golebiewska A, Obad N, Harter PN, Mittelbronn M, Bähr O, Weyerbrock A, Stuhr L, Miletic H, Sakariassen PØ, Stieber D, Rygh CB, Lund-Johansen M, ... ... Bjerkvig R, et al. Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas. Acta Neuropathologica. 129: 115-31. PMID 25322816 DOI: 10.1007/S00401-014-1352-5  0.384
2015 Johannessen TA, Grudic A, Zhu H, Saed H, Varughese J, Yang N, Sundstrom T, Janji B, Wang J, Lund-Johansen M, Bjerkvig R, Prestegarden L. Targeting dopamine receptor 2 (DRD2) signaling in combination with temozolomide chemotherapy as a novel therapeutic concept in glioblastomas. Journal of Clinical Oncology. 33: 2069-2069. DOI: 10.1200/Jco.2015.33.15_Suppl.2069  0.346
2015 Zhu H, Yang N, Leiss L, Rygh CB, Enger PØ, Bjerkvig R, Wang J. CD47 antibody inhibits tumor recurrence in a clinical relevant glioblastoma animal model Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P249  0.361
2015 Zhu H, Yang N, Leiss L, Rygh CB, Mitra SS, Cheshier SH, Huang B, Bjerkvig R, Enger PØ, Weissman IL, Li X, Wang J. Abstract 1331: Targeting CD47 triggers macrophage-dependent brain tumor destruction in a clinical relevant model Cancer Research. 75: 1331-1331. DOI: 10.1158/1538-7445.Am2015-1331  0.414
2015 Fack F, Hochart G, Oudin A, Leenders W, Gottlieb E, Bjerkvig R, Stauber J, Niclou S. Metb-09Identifying Novel Vulnerabilities In Oxidative Stress Pathways In Idh1 Mutant Glioma Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov221.09  0.373
2015 Toome K, Willmore AA, Säälik P, Braun GB, Majzoub R, Safinya CR, Bjerkvig R, Teesalu T. DDEL-19PENETRATION OF HOMING PEPTIDE-FUNCTIONALIZED NANOPARTICLES TO GLIOMA SPHEROIDS IN VITRO Neuro-Oncology. 17: v77.3-v77. DOI: 10.1093/Neuonc/Nov212.19  0.368
2015 Sundstrøm T, Varughese J, Prestegarden L, Azuaje F, Røsland GV, Skaftnesmo KO, Ingham ES, Even L, Tam S, Tepper C, Petersen K, Ferrara KW, Tronstad KJ, Lund-Johansen M, Bjerkvig R, et al. BMET-34DRUG REPURPOSING DISCOVERS BETA-SITOSTEROL AS AN EFFECTIVE THERAPEUTIC AGENT AGAINST MELANOMA BRAIN METASTASES IN VIVO Neuro-Oncology. 17: v52.3-v52. DOI: 10.1093/Neuonc/Nov208.34  0.409
2015 Obad N, Janji B, Prestegarden L, Espedal H, Hassan M, Keunen O, Sakariassen PØ, Lund-Johansen M, Niclou S, Bjerkvig R. Atps-59Improving Efficacy Of Bevacizumab Treatment In Glioblastoma By Targeting Hif1 Alpha Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov204.59  0.387
2014 Keunen O, Taxt T, Grüner R, Lund-Johansen M, Tonn JC, Pavlin T, Bjerkvig R, Niclou SP, Thorsen F. Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies. Advanced Drug Delivery Reviews. 76: 98-115. PMID 25078721 DOI: 10.1016/J.Addr.2014.07.010  0.403
2014 Szczepanski C, Tenstad O, Baumann A, Martinez A, Myklebust R, Bjerkvig R, Prestegarden L. Identification of a novel lytic peptide for the treatment of solid tumours. Genes & Cancer. 5: 186-200. PMID 25061502 DOI: 10.18632/Genesandcancer.18  0.341
2014 Daphu I, Horn S, Stieber D, Varughese JK, Spriet E, Dale HA, Skaftnesmo KO, Bjerkvig R, Thorsen F. In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways International Journal of Molecular Sciences. 15: 8773-8794. PMID 24840574 DOI: 10.3390/Ijms15058773  0.432
2014 Torsvik A, Stieber D, Enger PØ, Golebiewska A, Molven A, Svendsen A, Westermark B, Niclou SP, Olsen TK, Chekenya Enger M, Bjerkvig R. U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells. Cancer Medicine. 3: 812-24. PMID 24810477 DOI: 10.1002/Cam4.219  0.372
2014 van Lith SA, Navis AC, Verrijp K, Niclou SP, Bjerkvig R, Wesseling P, Tops B, Molenaar R, van Noorden CJ, Leenders WP. Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers? Biochimica Et Biophysica Acta. 1846: 66-74. PMID 24747768 DOI: 10.1016/J.Bbcan.2014.04.004  0.416
2014 Stieber D, Golebiewska A, Evers L, Lenkiewicz E, Brons NH, Nicot N, Oudin A, Bougnaud S, Hertel F, Bjerkvig R, Vallar L, Barrett MT, Niclou SP. Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes. Acta Neuropathologica. 127: 203-19. PMID 24154962 DOI: 10.1007/S00401-013-1196-4  0.355
2014 Sundstrøm T, Varughese JK, Azuaje F, Petersen K, Tepper CG, Ingham E, Even L, Tam S, Skaftnesmo KO, Lund-Johansen M, Bjerkvig R, Ferrara KW, Thorsen FA. Abstract 4036: Drug repurposing to treat melanoma brain metastases Cancer Research. 74: 4036-4036. DOI: 10.1158/1538-7445.Am2014-4036  0.432
2014 Miletic H, Talasila K, Rosland G, Eskilsson E, Azuaje F, Stieber D, Atai N, Hagland H, Tronstad K, Charalampos T, Noorden Rv, Niclou S, Thorsen F, Bjerkvig R. Tm-14The Angiogenic Switch Leads To A Metabolic Switch In Human Glioblastoma. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou278.13  0.473
2014 Prestegarden L, Johannessen T, Grudic A, Sundstrøm T, Saed H, Varughese J, Lund-Johansen M, Bjerkvig R. DS-04DOPAMINE ADDICTION IN GLIOBLASTOMA MULTIFORME DURING CHEMOTHERAPY IS MEDIATED BY A DRD2/β-ARRESTIN/AKT SIGNALING COMPLEX Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou244.4  0.395
2014 Sundstrom T, Varughese J, Azuaje F, Prestegarden L, Petersen K, Tepper C, Ingham E, Even L, Johnson S, Skaftnesmo KO, Lund-Johansen M, Bjerkvig R, Ferrara K, Thorsen F. BM-34 * NEW USES OF OLD DRUGS FOR THE CLINICAL TREATMENT OF BRAIN METASTASES Neuro-Oncology. 16: v39-v39. DOI: 10.1093/Neuonc/Nou240.33  0.425
2014 Eskilsson E, Røsland G, Talasila K, Jahedi R, Leiss L, Saed H, Keunen O, Foerster S, Euskirchen P, Hossain J, Taxt T, Jirik R, Lund-Johansen M, Enger PØ, Ritter C, ... ... Bjerkvig R, et al. AI-10DISTINCT EGFR SIGNALING IN GLIOBLASTOMA: WILD-TYPE EGFR PROMOTES INVASION WHILE EGFRvIII DRIVES PROTOTYPICAL SFK c-SRC ACTIVATION TO FOSTER ANGIOGENESIS. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou238.10  0.418
2014 Bjerkvig R, Fack F, Frezza C, Keunen O, Stieber D, Lund-Johansen M, Miletic H, Gottlieb E, Niclou SP. Mapping The Glioblastoma Metabolome After Bevacizumab Therapy By 13C6-Glucose Metabolomic Flux Analysis. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou208.35  0.408
2014 Niclou SP, Fack F, Hochart G, Oudin A, Leenders W, Gottlieb E, Bjerkvig R, Stauber J. In Situ Metabolic Profiling Sheds Light On Oxidative Stress Pathways In Idh1 Mutant Oligodendroglioma Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou206.39  0.386
2014 Fack F, Espedal H, Keunen O, Golebiewska A, Obad N, Zheng L, Gotlieb E, Harter P, Niclou S, Bjerkvig R. O10.03Physiological And Biological Responses Of Human Glioblastomas To Bevacizumab Treatment Assessed By Metabolomic Flux Analysis Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou174.84  0.419
2014 Eskilsson E, Røsland GV, Talasila KM, Leiss L, Saed HS, Lund-Johansen M, Enger P, Ritter C, Bjerkvig R, Miletic H. P17.30Oncogenic Egfrviii Drives Prototypical Sfk C-Src Activation To Promote Glioblastoma Angiogenesis. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou174.359  0.439
2014 Keunen O, Obad N, Espedal H, Jiřík R, Rygh CB, Taxt T, Sakariassen P, Fack F, Niclou SP, Bjerkvig R. P16.24Multimodal Imaging Elucidates Physiological And Metabolic Changes Induced By Anti-Angiogenic Therapy In Glioblastoma Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou174.319  0.315
2014 Johannessen TA, Grudic A, Sundstrøm T, Varughese JK, Lund-Johansen M, Bjerkvig R, Prestegarden L. P01.19A Genome-Wide Rnai Synthetic Lethal Screen For Sensitizers Of Glioblastoma Multiforme To Temozolomide. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou174.112  0.362
2013 Talasila KM, Brekka N, Mangseth K, Stieber D, Evensen L, Rosland GV, Torsvik A, Wagner M, Niclou SP, Mahesparan R, Vintermyr OK, Bjerkvig R, Nigro JM, Miletic H. Tumor versus stromal cells in culture--survival of the fittest? Plos One. 8: e81183. PMID 24349039 DOI: 10.1371/Journal.Pone.0081183  0.458
2013 Podergajs N, Brekka N, Radlwimmer B, Herold-Mende C, Talasila KM, Tiemann K, Rajcevic U, Lah TT, Bjerkvig R, Miletic H. Expansive growth of two glioblastoma stem-like cell lines is mediated by bFGF and not by EGF. Radiology and Oncology. 47: 330-7. PMID 24294177 DOI: 10.2478/Raon-2013-0063  0.358
2013 Eisenreich S, Abou-El-Ardat K, Szafranski K, Campos Valenzuela JA, Rump A, Nigro JM, Bjerkvig R, Gerlach EM, Hackmann K, Schröck E, Krex D, Kaderali L, Schackert G, Platzer M, Klink B. Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing. Plos One. 8: e76623. PMID 24086756 DOI: 10.1371/Journal.Pone.0076623  0.373
2013 Primon M, Huszthy PC, Motaln H, Talasila KM, Torkar A, Bjerkvig R, Lah Turnšek T. Cathepsin L silencing enhances arsenic trioxide mediated in vitro cytotoxicity and apoptosis in glioblastoma U87MG spheroids. Experimental Cell Research. 319: 2637-48. PMID 23968587 DOI: 10.1016/J.Yexcr.2013.08.011  0.378
2013 Petersen K, Rajcevic U, Abdul Rahim SA, Jonassen I, Kalland KH, Jimenez CR, Bjerkvig R, Niclou SP. Gene set based integrated data analysis reveals phenotypic differences in a brain cancer model. Plos One. 8: e68288. PMID 23874576 DOI: 10.1371/Journal.Pone.0068288  0.353
2013 Klink B, Miletic H, Stieber D, Huszthy PC, Campos Valenzuela JA, Valenzuela JA, Balss J, Wang J, Schubert M, Sakariassen PØ, Sundstrøm T, Torsvik A, Aarhus M, Mahesparan R, von Deimling A, ... ... Bjerkvig R, et al. A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. Plos One. 8: e59773. PMID 23527265 DOI: 10.1371/Journal.Pone.0059773  0.482
2013 Jarzabek MA, Huszthy PC, Skaftnesmo KO, McCormack E, Dicker P, Prehn JH, Bjerkvig R, Byrne AT. In vivo bioluminescence imaging validation of a human biopsy-derived orthotopic mouse model of glioblastoma multiforme. Molecular Imaging. 12: 161-72. PMID 23490442 DOI: 10.2310/7290.2012.00029  0.46
2013 Golebiewska A, Bougnaud S, Stieber D, Brons NH, Vallar L, Hertel F, Klink B, Schröck E, Bjerkvig R, Niclou SP. Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells. Brain : a Journal of Neurology. 136: 1462-75. PMID 23460667 DOI: 10.1093/Brain/Awt025  0.432
2013 Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Sakariassen PØ, Eskilsson E, Stieber D, Keunen O, Brekka N, Moen I, Nigro JM, ... ... Bjerkvig R, et al. EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis. Acta Neuropathologica. 125: 683-98. PMID 23429996 DOI: 10.1007/S00401-013-1101-1  0.443
2013 Sundstrøm T, Daphu I, Wendelbo I, Hodneland E, Lundervold A, Immervoll H, Skaftnesmo KO, Babic M, Jendelova P, Sykova E, Lund-Johansen M, Bjerkvig R, Thorsen F. Automated tracking of nanoparticle-labeled melanoma cells improves the predictive power of a brain metastasis model. Cancer Research. 73: 2445-56. PMID 23423977 DOI: 10.1158/0008-5472.Can-12-3514  0.434
2013 Daphu I, Sundstrøm T, Horn S, Huszthy PC, Niclou SP, Sakariassen PØ, Immervoll H, Miletic H, Bjerkvig R, Thorsen F. In vivo animal models for studying brain metastasis: value and limitations. Clinical & Experimental Metastasis. 30: 695-710. PMID 23322381 DOI: 10.1007/S10585-013-9566-9  0.372
2013 Johannessen TC, Wagner M, Straume O, Bjerkvig R, Eikesdal HP. Tumor vasculature: the Achilles' heel of cancer? Expert Opinion On Therapeutic Targets. 17: 7-20. PMID 23121690 DOI: 10.1517/14728222.2013.730522  0.385
2013 Torsvik A, Bjerkvig R. Mesenchymal stem cell signaling in cancer progression. Cancer Treatment Reviews. 39: 180-8. PMID 22494966 DOI: 10.1016/J.Ctrv.2012.03.005  0.381
2013 Eskilsson E, Talasila KM, Røsland GV, Leiss L, Brekkå N, Sakariassen PØ, Enger PØ, Bjerkvig R, Miletic H. Abstract B84: Activated c-Src enhances hypoxia in human glioblastoma multiforme and promotes tumor angiogenesis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-B84  0.345
2013 Tysnes BB, Sætran HA, Mørk SJ, Margaryan NV, Eide GE, Bjerkvig R, Strizzi L, Hendrix MJC. Abstract 2650: Age-dependent association between protein expression of the embryonic stem cell marker Cripto-1 and survival of glioblastoma patients. Cancer Research. 73: 2650-2650. DOI: 10.1158/1538-7445.Am2013-2650  0.445
2013 Agarwal M, Nitta R, Dovat S, Li G, Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, ... ... Bjerkvig R, et al. CELL BIOLOGY AND SIGNALING Neuro-Oncology. 15: iii12-iii31. DOI: 10.1093/Neuonc/Not174  0.301
2012 Torsvik A, Røsland GV, Bjerkvig R. Spontaneous transformation of stem cells in vitro and the issue of cross-contamination. International Journal of Biological Sciences. 8: 1051-2; discussion 1. PMID 22949886 DOI: 10.7150/Ijbs.3665  0.361
2012 Huszthy PC, Daphu I, Niclou SP, Stieber D, Nigro JM, Sakariassen PØ, Miletic H, Thorsen F, Bjerkvig R. In vivo models of primary brain tumors: pitfalls and perspectives. Neuro-Oncology. 14: 979-93. PMID 22679124 DOI: 10.1093/Neuonc/Nos135  0.431
2012 Wagner M, Bjerkvig R, Wiig H, Melero-Martin JM, Lin RZ, Klagsbrun M, Dudley AC. Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis. Angiogenesis. 15: 481-95. PMID 22614697 DOI: 10.1007/S10456-012-9276-Y  0.39
2012 Johannessen TC, Bjerkvig R. Molecular mechanisms of temozolomide resistance in glioblastoma multiforme. Expert Review of Anticancer Therapy. 12: 635-42. PMID 22594898 DOI: 10.1586/Era.12.37  0.314
2012 Najbauer J, Huszthy PC, Barish ME, Garcia E, Metz MZ, Myers SM, Gutova M, Frank RT, Miletic H, Kendall SE, Glackin CA, Bjerkvig R, Aboody KS. Cellular host responses to gliomas. Plos One. 7: e35150. PMID 22539956 DOI: 10.1371/Journal.Pone.0035150  0.501
2012 Gole B, Huszthy PC, Popović M, Jeruc J, Ardebili YS, Bjerkvig R, Lah TT. The regulation of cysteine cathepsins and cystatins in human gliomas. International Journal of Cancer. 131: 1779-89. PMID 22287159 DOI: 10.1002/Ijc.27453  0.443
2012 Torsvik A, Røsland GV, Bjerkvig R. Comment to: "Spontaneous transformation of adult mesenchymal stem cells from cynomolgus macaques in vitro" by Z. Ren et al. Exp. Cell Res. 317 (2011) 2950-2957: spontaneous transformation of mesenchymal stem cells in culture: facts or fiction? Experimental Cell Research. 318: 441-3. PMID 22227410 DOI: 10.1016/J.Yexcr.2011.12.009  0.316
2012 Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Sakariassen PØ, Eskilsson E, Keunen O, Brekka N, Moen I, Nigro J, Vintermyr O, ... ... Bjerkvig R, et al. Abstract LB-518: Amplification and activation of EGFR wild-type mediates invasion of human glioblastoma in vivo Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-518  0.44
2012 Røsland GV, Talasila K, Bjerkvig R, Miletic H. Abstract 5279: Over-expression of EGFRviii induces an angiogenic switch in infiltrative human glioblastomas Cancer Research. 72: 5279-5279. DOI: 10.1158/1538-7445.Am2012-5279  0.464
2012 Kozono D, Nitta M, Sampetrean O, Kimberly N, Kushwaha D, Merzon D, Ligon K, Zhu S, Zhu K, Kim TH, Kwon C, Becher O, Saya H, Chen CC, Donovan LK, ... ... Bjerkvig R, et al. LAB-STEM CELLS Neuro-Oncology. 14: vi142-vi152. DOI: 10.1093/Neuonc/Nos239  0.301
2012 Golebiewska A, Bougnaud S, Stieber D, Brons NHC, Vallar L, Hertel F, Bjerkvig R, Niclou SP. 249 Side Population in Human Glioblastoma Does Not Characterize Cancer Stem Cell Populations and is Exclusively Stroma-derived European Journal of Cancer. 48. DOI: 10.1016/S0959-8049(12)70944-9  0.42
2011 Euskirchen P, Skaftnesmo KO, Huszthy PC, BrekkÃ¥ N, Bjerkvig R, Jacobs AH, Miletic H. NUMB does not impair growth and differentiation status of experimental gliomas. Experimental Cell Research. 317: 2864-73. PMID 21939656 DOI: 10.1016/J.Yexcr.2011.09.002  0.46
2011 Svendsen A, Verhoeff JJ, Immervoll H, Brøgger JC, Kmiecik J, Poli A, Netland IA, Prestegarden L, Planagumà J, Torsvik A, Kjersem AB, Sakariassen PØ, Heggdal JI, Van Furth WR, Bjerkvig R, et al. Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma. Acta Neuropathologica. 122: 495-510. PMID 21863242 DOI: 10.1007/S00401-011-0867-2  0.375
2011 Wang J, Svendsen A, Kmiecik J, Immervoll H, Skaftnesmo KO, Planagumà J, Reed RK, Bjerkvig R, Miletic H, Enger PØ, Rygh CB, Chekenya M. Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma. Plos One. 6: e23062. PMID 21829586 DOI: 10.1371/Journal.Pone.0023062  0.387
2011 Atai NA, Renkema-Mills NA, Bosman J, Schmidt N, Rijkeboer D, Tigchelaar W, Bosch KS, Troost D, Jonker A, Bleeker FE, Miletic H, Bjerkvig R, De Witt Hamer PC, Van Noorden CJ. Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 59: 489-503. PMID 21527585 DOI: 10.1369/0022155411400606  0.335
2011 Keunen O, Johansson M, Oudin A, Sanzey M, Rahim SA, Fack F, Thorsen F, Taxt T, Bartos M, Jirik R, Miletic H, Wang J, Stieber D, Stuhr L, Moen I, ... ... Bjerkvig R, et al. Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 108: 3749-54. PMID 21321221 DOI: 10.1073/Pnas.1014480108  0.467
2011 Golebiewska A, Brons NH, Bjerkvig R, Niclou SP. Critical appraisal of the side population assay in stem cell and cancer stem cell research. Cell Stem Cell. 8: 136-47. PMID 21295271 DOI: 10.1016/J.Stem.2011.01.007  0.319
2011 Duenisch P, Reichart R, Mueller U, Brodhun M, Bjerkvig R, Romeike B, Walter J, Herbold C, Regenbrecht CR, Kalff R, Kuhn SA. Neural cell adhesion molecule isoform 140 declines with rise of WHO grade in human gliomas and serves as indicator for the invasion zone of multiform glioblastomas and brain metastases. Journal of Cancer Research and Clinical Oncology. 137: 399-414. PMID 20440511 DOI: 10.1007/S00432-010-0888-6  0.451
2011 Daphu IK, Wendelbo I, Immervoll H, Sykova E, Jendelova P, Babic M, Bjerkvig R, Thorsen F. Abstract 5229: Single, pre-labeled metastatic melanoma cells can be detected in the mouse brain using MRI Cancer Research. 71: 5229-5229. DOI: 10.1158/1538-7445.Am2011-5229  0.442
2011 Johannessen TA, Prestegarden L, Grudic A, Tysnes BB, Bjerkvig R. Abstract 1725: Activation of the p53 pathway by the MDM2 antagonist nutlin-3 downregulates the DNA repair protein hABH2 and sensitizes glioma cells to chemotherapy Cancer Research. 71: 1725-1725. DOI: 10.1158/1538-7445.Am2011-1725  0.378
2011 Niclou SP, Golebiewska A, Stiebe D, Bjerkvig R. 161 INVITED Stem Cells European Journal of Cancer. 47. DOI: 10.1016/S0959-8049(11)70376-8  0.301
2010 Goplen D, Bougnaud S, Rajcevic U, Bøe SO, Skaftnesmo KO, Voges J, Enger PØ, Wang J, Tysnes BB, Laerum OD, Niclou S, Bjerkvig R. αB-crystallin is elevated in highly infiltrative apoptosis-resistant glioblastoma cells. The American Journal of Pathology. 177: 1618-28. PMID 20813964 DOI: 10.2353/Ajpath.2010.090063  0.692
2010 Wiig H, Tenstad O, Iversen PO, Kalluri R, Bjerkvig R. Interstitial fluid: the overlooked component of the tumor microenvironment? Fibrogenesis & Tissue Repair. 3: 12. PMID 20653943 DOI: 10.1186/1755-1536-3-12  0.381
2010 Prestegarden L, Svendsen A, Wang J, Sleire L, Skaftnesmo KO, Bjerkvig R, Yan T, Askland L, Persson A, Sakariassen PØ, Enger PØ. Glioma cell populations grouped by different cell type markers drive brain tumor growth. Cancer Research. 70: 4274-9. PMID 20460538 DOI: 10.1158/0008-5472.Can-09-3904  0.449
2010 Christensen K, Aaberg-Jessen C, Andersen C, Goplen D, Bjerkvig R, Kristensen BW. Immunohistochemical expression of stem cell, endothelial cell, and chemosensitivity markers in primary glioma spheroids cultured in serum-containing and serum-free medium. Neurosurgery. 66: 933-47. PMID 20404698 DOI: 10.1227/01.Neu.0000368393.45935.46  0.335
2010 Huszthy PC, Immervoll H, Wang J, Goplen D, Miletic H, Eide GE, Bjerkvig R. Cellular effects of oncolytic viral therapy on the glioblastoma microenvironment Gene Therapy. 17: 202-216. PMID 19829315 DOI: 10.1038/Gt.2009.130  0.439
2010 Doucette TA, Kong L, Yang Y, Wei J, Wang J, Fuller GN, Heimberger AB, Rao G, Ajewung N, Kamnasaran D, Katz AM, Amankulor N, Squatrito M, Hambardzumyan D, Holland EC, ... ... Bjerkvig R, et al. Tumor Models (In Vivo/In Vitro) Neuro-Oncology. 12: iv130-iv136. DOI: 10.1093/Neuonc/Noq116.S20  0.391
2009 Wang J, Miletic H, Sakariassen PØ, Huszthy PC, Jacobsen H, Brekkå N, Li X, Zhao P, Mørk S, Chekenya M, Bjerkvig R, Enger PØ. A reproducible brain tumour model established from human glioblastoma biopsies. Bmc Cancer. 9: 465. PMID 20040089 DOI: 10.1186/1471-2407-9-465  0.372
2009 Thulin A, Ringvall M, Dimberg A, KÃ¥rehed K, Väisänen T, Väisänen MR, Hamad O, Wang J, Bjerkvig R, Nilsson B, Pihlajaniemi T, Akerud H, Pietras K, Jahnen-Dechent W, Siegbahn A, et al. Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein. Molecular Cancer Research : McR. 7: 1792-802. PMID 19903770 DOI: 10.1158/1541-7786.Mcr-09-0094  0.328
2009 Bjerkvig R, Johansson M, Miletic H, Niclou SP. Cancer stem cells and angiogenesis. Seminars in Cancer Biology. 19: 279-84. PMID 19818406 DOI: 10.1016/J.Semcancer.2009.09.001  0.407
2009 Rajcevic U, Petersen K, Knol JC, Loos M, Bougnaud S, Klychnikov O, Li KW, Pham TV, Wang J, Miletic H, Peng Z, Bjerkvig R, Jimenez CR, Niclou SP. iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype. Molecular & Cellular Proteomics : McP. 8: 2595-612. PMID 19674965 DOI: 10.1074/Mcp.M900124-Mcp200  0.461
2009 Huszthy PC, Giroglou T, Tsinkalovsky O, Euskirchen P, Skaftnesmo KO, Bjerkvig R, Laer Dv, Miletic H. Remission of Invasive, Cancer Stem-Like Glioblastoma Xenografts Using Lentiviral Vector-Mediated Suicide Gene Therapy Plos One. 4. PMID 19617915 DOI: 10.1371/Journal.Pone.0006314  0.446
2009 Røsland GV, Svendsen A, Torsvik A, Sobala E, McCormack E, Immervoll H, Mysliwietz J, Tonn JC, Goldbrunner R, Lønning PE, Bjerkvig R, Schichor C. Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation Cancer Research. 69: 5331-5339. PMID 19509230 DOI: 10.1158/0008-5472.Can-08-4630  0.364
2009 Miletic H, Niclou SP, Johansson M, Bjerkvig R. Anti-VEGF therapies for malignant glioma: treatment effects and escape mechanisms. Expert Opinion On Therapeutic Targets. 13: 455-468. PMID 19335067 DOI: 10.1517/14728220902806444  0.319
2009 Laerum OD, Steinsvåg S, Bjerkvig R. Cell and tissue culture of the central nervous system: Recent developments and current applications Acta Neurologica Scandinavica. 72: 529-549. PMID 3913271 DOI: 10.1111/J.1600-0404.1985.Tb00913.X  0.37
2009 Johannessen TA, Wang J, Skaftnesmo K, Sakariassen PØ, Enger PØ, Petersen K, Øyan AM, Kalland K, Bjerkvig R, Tysnes BB. Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell‐like phenotype Neuropathology and Applied Neurobiology. 35: 380-393. DOI: 10.1111/J.1365-2990.2009.01008.X  0.389
2008 Thorsen F, Jirak D, Wang J, Sykova E, Bjerkvig R, Enger PØ, van der Kogel A, Hajek M. Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics. Nmr in Biomedicine. 21: 830-8. PMID 18613001 DOI: 10.1002/Nbm.1263  0.435
2008 Johannessen TA, Bjerkvig R, Tysnes BB. DNA repair and cancer stem-like cells – Potential partners in glioma drug resistance? Cancer Treatment Reviews. 34: 558-567. PMID 18501520 DOI: 10.1016/J.Ctrv.2008.03.125  0.38
2008 Niclou SP, Danzeisen C, Eikesdal HP, Wiig H, Brons NH, Poli AM, Svendsen A, Torsvik A, Enger PØ, Terzis JA, Bjerkvig R. A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3120-8. PMID 18495755 DOI: 10.1096/Fj.08-109611  0.449
2008 Chekenya M, Krakstad C, Svendsen A, Netland IA, Staalesen V, Tysnes BB, Selheim F, Wang J, Sakariassen P, Sandal T, Lønning PE, Flatmark T, Enger P, Bjerkvig R, Sioud M, et al. The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling. Oncogene. 27: 5182-5194. PMID 18469852 DOI: 10.1038/Onc.2008.157  0.462
2008 Huszthy PC, Goplen D, Thorsen F, Immervoll H, Wang J, Gutermann A, Miletic H, Bjerkvig R. Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1571-80. PMID 18316582 DOI: 10.1158/1078-0432.Ccr-07-2000  0.37
2008 Wang J, Sakariassen PØ, Tsinkalovsky O, Immervoll H, Bøe SO, Svendsen A, Prestegarden L, Røsland G, Thorsen F, Stuhr L, Molven A, Bjerkvig R, Enger PØ. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. International Journal of Cancer. 122: 761-8. PMID 17955491 DOI: 10.1002/Ijc.23130  0.406
2008 Najbauer J, Barish ME, Garcia E, Metz MZ, Gutova M, Frank RT, Kendall SE, Glackin CA, Bjerkvig R, Aboody KS. Host cell recruitment by gliomas Ejc Supplements. 6: 71-72. DOI: 10.1016/S1359-6349(08)71450-2  0.345
2007 Sundlisæter E, Dicko A, Sakariassen PØ, Sondenaa K, Enger PØ, Bjerkvig R. Lymphangiogenesis in colorectal cancer--prognostic and therapeutic aspects. International Journal of Cancer. 121: 1401-1409. PMID 17640040 DOI: 10.1002/Ijc.22996  0.36
2007 Stuhr LEB, Raa A, Øyan AM, Kalland KH, Sakariassen PO, Petersen K, Bjerkvig R, Reed RK. Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats. Journal of Neuro-Oncology. 85: 191-202. PMID 17557137 DOI: 10.1007/S11060-007-9407-2  0.362
2007 Tysnes BB, Bjerkvig R. Cancer initiation and progression: Involvement of stem cells and the microenvironment Biochimica Et Biophysica Acta. 1775: 283-297. PMID 17374555 DOI: 10.1016/J.Bbcan.2007.01.001  0.448
2007 Raa A, Stansberg C, Steen VM, Bjerkvig R, Reed RK, Stuhr LEB. Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors Bmc Cancer. 7: 23-23. PMID 17263869 DOI: 10.1186/1471-2407-7-23  0.375
2007 Thorsen F, Enger PØ, Wang J, Bjerkvig R, Pedersen PH. Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery. Journal of Neuro-Oncology. 82: 1-10. PMID 16955221 DOI: 10.1007/S11060-006-9240-Z  0.374
2006 Sakariassen P, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, Sminia P, Sundlisæter E, Misra A, Tysnes BB, Chekenya M, Peters H, Lende G, Kalland KH, Øyan AM, ... ... Bjerkvig R, et al. Angiogenesis-independent tumor growth mediated by stem-like cancer cells Proceedings of the National Academy of Sciences of the United States of America. 103: 16466-16471. PMID 17056721 DOI: 10.1073/Pnas.0607668103  0.474
2006 Goplen D, Wang J, Enger PØ, Tysnes BB, Terzis AJ, Laerum OD, Bjerkvig R. Protein disulfide isomerase expression is related to the invasive properties of malignant glioma. Cancer Research. 66: 9895-902. PMID 17047051 DOI: 10.1158/0008-5472.Can-05-4589  0.689
2006 Sundlisaeter E, Wang J, Sakariassen PØ, Marie M, Mathisen JR, Karlsen BO, Prestegarden L, Skaftnesmo KO, Bjerkvig R, Enger PØ. Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation. Neuropathology and Applied Neurobiology. 32: 419-27. PMID 16866987 DOI: 10.1111/J.1365-2990.2006.00744.X  0.413
2006 Terzis AJA, Niclou SP, Rajcevic U, Danzeisen C, Bjerkvig R. Cell therapies for glioblastoma Expert Opinion On Biological Therapy. 6: 739-749. PMID 16856796 DOI: 10.1517/14712598.6.8.739  0.398
2006 Thorsen F, Afione S, Huszthy PC, Tysnes BB, Svendsen A, Bjerkvig R, Kotin RM, Lønning PE, Hoover F. Adeno-associated virus (AAV) serotypes 2, 4 and 5 display similar transduction profiles and penetrate solid tumor tissue in models of human glioma. The Journal of Gene Medicine. 8: 1131-40. PMID 16810631 DOI: 10.1002/Jgm.939  0.44
2006 Werbowetski-Ogilvie TE, Seyed Sadr M, Jabado N, Angers-Loustau A, Agar NYR, Wu J, Bjerkvig R, Antel JP, Faury D, Rao Y, Del Maestro RF. Inhibition of medulloblastoma cell invasion by Slit Oncogene. 25: 5103-5112. PMID 16636676 DOI: 10.1038/Sj.Onc.1209524  0.478
2006 Piepoli T, Jakupoglu C, Gu W, Lualdi E, Suarez-Merino B, Poliani PL, Cattaneo MG, Ortino B, Goplen D, Wang J, Mola R, Inverardi F, Frassoni C, Bjerkvig R, Steinlein O, et al. Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1. Neuro-Oncology. 8: 96-108. PMID 16533756 DOI: 10.1215/15228517-2005-006  0.349
2006 Huszthy PC, Brekken C, Pedersen TB, Thorsen F, Sakariassen PØ, Skaftnesmo KO, Haraldseth O, Lønning PE, Bjerkvig R, Enger PØ. Antitumor efficacy improved by local delivery of species-specific endostatin Journal of Neurosurgery. 104: 118-128. PMID 16509155 DOI: 10.3171/Jns.2006.104.1.118  0.434
2006 Brekke C, Lundervold A, Enger PØ, Brekken C, Stålsett E, Pedersen TB, Haraldseth O, Krüger PG, Bjerkvig R, Chekenya M. NG2 expression regulates vascular morphology and function in human brain tumours. Neuroimage. 29: 965-976. PMID 16253523 DOI: 10.1016/J.Neuroimage.2005.08.026  0.374
2005 Bjerkvig R, Tysnes BB, Aboody KS, Najbauer J, Terzis AJA. The origin of the cancer stem cell: current controversies and new insights Nature Reviews Cancer. 5: 899-904. PMID 16327766 DOI: 10.1038/Nrc1740  0.353
2005 Schichor C, Kerkau S, Visted T, Martini R, Bjerkvig R, Tonn JC, Goldbrunner R. The brain slice chamber, a novel variation of the Boyden Chamber Assay, allows time-dependent quantification of glioma invasion into mammalian brain in vitro. Journal of Neuro-Oncology. 73: 9-18. PMID 15933811 DOI: 10.1007/S11060-004-3341-3  0.425
2005 Huszthy PC, Svendsen A, Wilson JM, Kotin RM, Lønning PE, Bjerkvig R, Hoover F. Widespread dispersion of adeno-associated virus serotype 1 and adeno-associated virus serotype 6 vectors in the rat central nervous system and in human glioblastoma multiforme xenografts. Human Gene Therapy. 16: 381-92. PMID 15812233 DOI: 10.1089/Hum.2005.16.381  0.39
2004 Werbowetski T, Bjerkvig R, Maestro RFD. Evidence for a secreted chemorepellent that directs glioma cell invasion. Journal of Neurobiology. 60: 71-88. PMID 15188274 DOI: 10.1002/Neu.10335  0.435
2004 Stensvaag V, Furmanek T, Lønning K, Terzis AJA, Bjerkvig R, Visted T. Cryopreservation of alginate-encapsulated recombinant cells for antiangiogenic therapy. Cell Transplantation. 13: 35-44. PMID 15040603 DOI: 10.3727/000000004772664879  0.429
2004 Fischer W, Gustafsson L, Mossberg AK, Gronli J, Mork S, Bjerkvig R, Svanborg C. Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival. Cancer Research. 64: 2105-12. PMID 15026350 DOI: 10.1158/0008-5472.Can-03-2661  0.476
2003 Visted T, Furmanek T, Sakariassen P, Foegler WB, Sim K, Westphal H, Bjerkvig R, Lund-Johansen M. Prospects for delivery of recombinant angiostatin by cell-encapsulation therapy. Human Gene Therapy. 14: 1429-1440. PMID 14577923 DOI: 10.1089/104303403769211646  0.393
2003 Bjerkvig R, Read TA, Vajkoczy P, Aebischer P, Pralong W, Platt S, Melvik JE, Hagen A, Dornish M. Cell therapy using encapsulated cells producing endostatin. Acta Neurochirurgica. Supplement. 88: 137-41. PMID 14531571 DOI: 10.1007/978-3-7091-6090-9_19  0.476
2003 Thorsen F, Ersland L, Nordli H, Enger PO, Huszthy PC, Lundervold A, Standnes T, Bjerkvig R, Lund-Johansen M. Imaging of experimental rat gliomas using a clinical MR scanner. Journal of Neuro-Oncology. 63: 225-31. PMID 12892228 DOI: 10.1023/A:1024241905888  0.342
2003 Wilhelmsson U, Eliasson C, Bjerkvig R, Pekny M. Loss of GFAP expression in high-grade astrocytomas does not contribute to tumor development or progression. Oncogene. 22: 3407-3411. PMID 12776191 DOI: 10.1038/Sj.Onc.1206372  0.397
2003 Visted T, Enger PO, Lund-Johansen M, Bjerkvig R. Mechanisms of tumor cell invasion and angiogenesis in the central nervous system. Frontiers in Bioscience. 8. PMID 12700036 DOI: 10.2741/1026  0.471
2003 Svanborg C, Agerstam H, Aronson A, Bjerkvig R, Düringer C, Fischer W, Gustafsson L, Hallgren O, Leijonhuvud I, Linse S, Mossberg AK, Nilsson H, Pettersson J, Svensson M. HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects. Advances in Cancer Research. 88: 1-29. PMID 12665051 DOI: 10.1016/S0065-230X(03)88302-1  0.445
2003 Mahesparan R, Read TA, Lund-Johansen M, Skaftnesmo KO, Bjerkvig R, Engebraaten O. Expression of extracellular matrix components in a highly infiltrative in vivo glioma model. Acta Neuropathologica. 105: 49-57. PMID 12471461 DOI: 10.1007/S00401-002-0610-0  0.476
2002 Chekenya M, Enger PØ, Thorsen F, Tysnes BB, Al-Sarraj S, Read TA, Furmanek T, Mahesparan R, Levine JM, Butt AM, Pilkington GJ, Bjerkvig R. The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumours. Neuropathology and Applied Neurobiology. 28: 367-80. PMID 12366818 DOI: 10.1046/J.1365-2990.2002.00412.X  0.364
2002 Read TA, Thorsen F, Bjerkvig R. Localised delivery of therapeutic agents to CNS malignancies: old and new approaches. Current Pharmaceutical Biotechnology. 3: 257-73. PMID 12164481 DOI: 10.2174/1389201023378346  0.39
2002 Enger PØ, Thorsen F, Lønning PE, Bjerkvig R, Hoover F. Adeno-Associated Viral Vectors Penetrate Human Solid Tumor Tissue In Vivo More Effectively than Adenoviral Vectors Human Gene Therapy. 13: 1115-1125. PMID 12067444 DOI: 10.1089/104303402753812511  0.323
2002 Chekenya M, Hjelstuen M, Enger PØ, Thorsen F, Jacob AL, Probst B, Haraldseth O, Pilkington G, Butt A, Levine JM, Bjerkvig R. NG2 proteoglycan promotes angiogenesis-dependent tumor growth in CNS by sequestering angiostatin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 586-8. PMID 11919162 DOI: 10.1096/Fj.01-0632Fje  0.428
2002 Sorensen DR, Read TA, Porwol T, Olsen BR, Timpl R, Sasaki T, Iversen PO, Benestad HB, Sim BK, Bjerkvig R. Endostatin reduces vascularization, blood flow, and growth in a rat gliosarcoma. Neuro-Oncology. 4: 1-8. PMID 11772427 DOI: 10.1093/Neuonc/4.1.1  0.432
2002 Tronstad KJ, Berge K, Bjerkvig R, Flatmark T, Berge RK. Metabolic effects of 3-thia fatty acid in cancer cells. Advances in Experimental Medicine and Biology. 466: 201-204. PMID 10709645 DOI: 10.1007/0-306-46818-2_23  0.335
2001 Hedberg KM, Mahesparan R, Read TA, Tysnes BB, Thorsen F, Visted T, Bjerkvig R, Fredman P. The glioma-associated gangliosides 3'-isoLM1, GD3 and GM2 show selective area expression in human glioblastoma xenografts in nude rat brains. Neuropathology and Applied Neurobiology. 27: 451-64. PMID 11903928 DOI: 10.1046/J.1365-2990.2001.00353.X  0.379
2001 Tysnes BB, Maurert HR, Porwol T, Probst B, Bjerkvig R, Hoover F. Bromelain Reversibly Inhibits Invasive Properties of Glioma Cells Neoplasia. 3: 469-479. PMID 11774029 DOI: 10.1038/Sj.Neo.7900196  0.389
2001 Eikesdal HP, Bjerkvig R, Raleigh JA, Mella O, Dahl O. Tumor vasculature is targeted by the combination of combretastatin A-4 and hyperthermia. Radiotherapy and Oncology. 61: 313-320. PMID 11731002 DOI: 10.1016/S0167-8140(01)00450-9  0.374
2001 Eikesdal HP, Bjerkvig R, Dahl O. Vinblastine and hyperthermia target the neovasculature in BT(4)AN rat gliomas: therapeutic implications of the vascular phenotype. International Journal of Radiation Oncology Biology Physics. 51: 535-544. PMID 11567830 DOI: 10.1016/S0360-3016(01)01693-5  0.432
2001 Visted T, Bjerkvig R, Enger PØ. Cell encapsulation technology as a therapeutic strategy for CNS malignancies. Neuro-Oncology. 3: 201-210. PMID 11465401 DOI: 10.1093/Neuonc/3.3.201  0.436
2001 Eikesdal HP, Bjerkvig R, Mella O, Dahl O. Combretastatin A-4 and hyperthermia;a potent combination for the treatment of solid tumors. Radiotherapy and Oncology. 60: 147-154. PMID 11439209 DOI: 10.1016/S0167-8140(00)00318-2  0.372
2001 Read TA, Sorensen DR, Mahesparan R, Enger PO, Timpl R, Olsen BR, Hjelstuen MH, Haraldseth O, Bjerkvig R. Local endostatin treatment of gliomas administered by microencapsulated producer cells. Nature Biotechnology. 19: 29-34. PMID 11135548 DOI: 10.1038/83471  0.473
2000 Thorsen F, Read TA, Lund-Johansen M, Tysnes BB, Bjerkvig R. Alginate-encapsulated producer cells: a potential new approach for the treatment of malignant brain tumors. Cell Transplantation. 9: 773-83. PMID 11202564 DOI: 10.1177/096368970000900604  0.484
2000 Sandmair A, Turunen M, Tyynelä K, Loimas S, Vainio P, Vanninen R, Vapalahti M, Bjerkvig R, Jänne J, Ylä-Herttuala S. Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions. Cancer Gene Therapy. 7: 413-421. PMID 10766347 DOI: 10.1038/Sj.Cgt.7700132  0.484
2000 Visted T, Thorsen J, Thorsen F, Read TA, Ulvestad E, Engebraaten O, Sorensen D, Ylä-Herttuala S, Tyynela K, Rucklidge G, Edvardsen K, Bjerkvig R, Lund-Johansen M. lacZ-neoR transfected glioma cells in syngeneic rats: growth pattern and characterization of the host immune response against cells transplanted inside and outside the CNS. International Journal of Cancer. Journal International Du Cancer. 85: 228-35. PMID 10629082 DOI: 10.1002/(Sici)1097-0215(20000115)85:2<228::Aid-Ijc13>3.0.Co;2-9  0.458
1999 Øyvind PE, Visted T, Thorsen F, Bjerkvig R, Lund-Johansen M. Retroviral transfection of the lacZ gene from Liz-9 packaging cells to glioma spheroids. International Journal of Developmental Neuroscience. 17: 665-672. PMID 10571426 DOI: 10.1016/S0736-5748(99)00022-2  0.387
1999 Read TA, Stensvaag V, Vindenes H, Ulvestad E, Bjerkvig R, Thorsen F. Cells encapsulated in alginate: a potential system for delivery of recombinant proteins to malignant brain tumours. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 17: 653-63. PMID 10571425 DOI: 10.1016/S0736-5748(99)00052-0  0.43
1999 Tysnes BB, Mahesparan R, Thorsen F, Haugland HK, Porwol T, Enger PØ, Lund-Johansen M, Bjerkvig R. Laminin expression by glial fibrillary acidic protein positive cells in human gliomas. International Journal of Developmental Neuroscience. 17: 531-539. PMID 10571414 DOI: 10.1016/S0736-5748(99)00055-6  0.46
1999 Rødahl E, Pedersen P, Bjerkvig R, Haarr L. Infection of rat brain cell aggregates with neurovirulent and nonneurovirulent strains of herpes simplex virus type 1. Experimental Cell Research. 248: 306-313. PMID 10094836 DOI: 10.1006/Excr.1998.4348  0.316
1999 Mahesparan R, Tysnes BB, Read TA, Enger PO, Bjerkvig R, Lund-Johansen M. Extracellular matrix-induced cell migration from glioblastoma biopsy specimens in vitro. Acta Neuropathologica. 97: 231-9. PMID 10090669 DOI: 10.1007/S004010050979  0.414
1998 Fjellbirkeland L, Laerum OD, Eide GE, Bjerkvig R. Invasiveness by lacZ transfected non-small-cell lung cancer cells into human bronchial tissues in vitro. Lung Cancer. 21: 7-19. PMID 9792049 DOI: 10.1016/S0169-5002(98)00037-3  0.477
1998 Fjellbirkeland L, Bjerkvig R, Laerum OD. Non-small-cell lung carcinoma cells invade human bronchial mucosa in vitro. In Vitro Cellular & Developmental Biology – Animal. 34: 333-340. PMID 9590507 DOI: 10.1007/S11626-998-0010-4  0.443
1998 Terzis AJA, Pedersen PH, Feuerstein BG, Arnold H, Bjerkvig R, Deen DF. Effects of DFMO on glioma cell proliferation, migration and invasion in vitro Journal of Neuro-Oncology. 36: 113-121. PMID 9525811 DOI: 10.1023/A:1005811403041  0.447
1998 Knott JC, Mahesparan R, Garcia-Cabrera I, Bølge Tysnes B, Edvardsen K, Ness GO, Mørk S, Lund-Johansen M, Bjerkvig R. Stimulation of extracellular matrix components in the normal brain by invading glioma cells. International Journal of Cancer. Journal International Du Cancer. 75: 864-72. PMID 9506531 DOI: 10.1002/(Sici)1097-0215(19980316)75:6<864::Aid-Ijc8>3.0.Co;2-T  0.469
1998 Nygaard SJT, Haugland HKR, Laerum OD, Lund-Johansen M, Bjerkvig R, Tysnes O. Dynamic determination of human glioma invasion in vitro Journal of Neurosurgery. 89: 441-447. DOI: 10.3171/Jns.1998.89.3.0441  0.484
1997 Chintala SK, Fueyo J, Gomez-Manzano C, Venkaiah B, Bjerkvig R, Yung WK, Sawaya R, Kyritsis AP, Rao JS. Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro. Oncogene. 15: 2049-57. PMID 9366522 DOI: 10.1038/Sj.Onc.1201382  0.446
1997 Bjerkvig R, Lund-Johansen M, Edvardsen K. Tumor cell invasion and angiogenesis in the central nervous system. Current Opinion in Oncology. 9: 223-229. PMID 9229143 DOI: 10.1097/00001622-199709030-00002  0.486
1997 Go Y, Chintala SK, Mohanam S, Gokaslan Z, Venkaiah B, Bjerkvig R, Oka K, Nicolson GL, Sawaya R, Rao JS. Inhibition of in vivo tumorigenicity and invasiveness of a human glioblastoma cell line transfected with antisense uPAR vectors. Clinical & Experimental Metastasis. 15: 440-6. PMID 9219733 DOI: 10.1023/A:1018410523635  0.475
1997 Thorsen F, Visted T, Lehtolainen P, Ylä-Herttuala S, Bjerkvig R. Release of replication-deficient retroviruses from a packaging cell line: interaction with glioma tumor spheroids in vitro. International Journal of Cancer. 71: 874-880. PMID 9180159 DOI: 10.1002/(Sici)1097-0215(19970529)71:5<874::Aid-Ijc28>3.0.Co;2-6  0.441
1997 Mahesparan R, Tysnes BB, Edvardsen K, Haugeland HK, Cabrera IG, Lund-Johansen M, Engebraaten O, Bjerkvig R. Role of high molecular weight extracellular matrix proteins in glioma cell migration Neuropathology and Applied Neurobiology. 23: 102-112. DOI: 10.1111/J.1365-2990.1997.Tb01192.X  0.399
1997 Thorsen F, Edvardsen K, Bjerkvig R, Mørk S. Retrovirus Production From Packaging Cells And Gene Transfer. Into Spheroids Of Glioma Origin Journal of Neuropathology and Experimental Neurology. 56: 584. DOI: 10.1097/00005072-199705000-00064  0.309
1997 Heese O, Thorsen F, Sepehrnia A, Terzis AJA, Bjerkvig R, Arnold H. Microtubules as a target for chemotherapeutic agents: Paclitaxel (Taxol®) inhibits invasion of glioma cells Clinical Neurology and Neurosurgery. 99. DOI: 10.1016/S0303-8467(97)81375-3  0.352
1996 Tysnes BB, Larsen LF, Ness GO, Mahesparan R, Edvardsen K, Garcia-Cabrera I, Bjerkvig R. Stimulation of glioma‐cell migration by laminin and inhibition by anti‐α3 and anti‐β1 integrin antibodies International Journal of Cancer. 67: 777-784. PMID 8824548 DOI: 10.1002/(Sici)1097-0215(19960917)67:6<777::Aid-Ijc5>3.0.Co;2-O  0.392
1996 Fjellbirkeland L, Bjerkvig R, Steinsvag SK, Laerum OD. Nonadhesive Stationary Organ Culture of Human Bronchial Mucosa American Journal of Respiratory Cell and Molecular Biology. 15: 197-206. PMID 8703475 DOI: 10.1165/Ajrcmb.15.2.8703475  0.303
1995 Brustugun OT, Mellgren G, Gjertsen BT, Bjerkvig R, Døskeland SO. Sensitive and rapid detection of β-galactosidase expression in intact cells by microinjection of fluorescent substrate Experimental Cell Research. 219: 372-378. PMID 7641787 DOI: 10.1006/Excr.1995.1241  0.307
1994 Pedersen P‐, Ness GO, Engebraaten O, Bjerkvig R, Lillehaug JR, Laerum OD. Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-α, bFGF, IL-2] on glioma spheroid growth, migration and invasion International Journal of Cancer. 56: 255-261. PMID 8314309 DOI: 10.1002/Ijc.2910560219  0.36
1994 Terzis AJA, Arnold H, Laerum OD, Bjerkvig R. Interaction between human medulloblastomas and foetal rat brain aggregates in vitro. Acta Neurochirurgica. 126: 11-16. PMID 8154316 DOI: 10.1007/Bf01476488  0.417
1994 Ness GO, Pedersen P, Bjerkvig R, Laerum OD, Lillehaug JR. Three-dimensional growth of glial cell lines affects growth factor and growth factor receptor mRNA levels. Experimental Cell Research. 214: 433-436. PMID 8082746 DOI: 10.1006/Excr.1994.1277  0.312
1994 Marienhagen K, Pedersen P-, Terzis AJA, Laerum OD, Arnold H, Bjerkvig R. Interactions between fetal rat brain cells and mature brain tissue in vivo and in vitro Neuropathology and Applied Neurobiology. 20: 130-143. PMID 8072644 DOI: 10.1111/J.1365-2990.1994.Tb01172.X  0.356
1994 Edvardsen K, Pedersen PH, Bjerkvig R, Hermann GG, Zeuthen J, Laerum OD, Walsh FS, Bock E. Transfection of glioma cells with the neural-cell adhesion molecule NCAM: effect on glioma-cell invasion and growth in vivo. International Journal of Cancer. Journal International Du Cancer. 58: 116-22. PMID 8014007 DOI: 10.1002/Ijc.2910580119  0.479
1994 Ulvestad E, Williams K, Bjerkvig R, Tiekotter K, Antel J, Matre R. Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells. Journal of Leukocyte Biology. 56: 732-740. PMID 7996050 DOI: 10.1002/Jlb.56.6.732  0.362
1994 Pedersen PH, Rucklidge GJ, Mørk SJ, Terzis AJ, Engebraaten O, Lund-Johansen M, Backlund EO, Laerum OD, Bjerkvig R. Leptomeningeal tissue: a barrier against brain tumor cell invasion. Journal of the National Cancer Institute. 86: 1593-9. PMID 7932823 DOI: 10.1093/Jnci/86.21.1593  0.492
1994 Wester K, Bjerkvig R, Cressey L, Engebraaten O, Mørk S. Organ culture of a glioblastoma from a patient with an unusually long survival. Neurosurgery. 35: 428-433. PMID 7800134 DOI: 10.1227/00006123-199409000-00010  0.466
1993 Terzis AJA, Arnold H, Fiskerstrand T, Refsum H, Ueland PM, Bjerkvig R. Proliferation, migration and invasion of human glioma cells exposed to antifolate drugs International Journal of Cancer. 54: 112-118. PMID 8478137 DOI: 10.1002/Ijc.2910540118  0.47
1993 Engebraaten O, Bjerkvig R, Pedersen P, Laerum OD. Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro International Journal of Cancer. 53: 209-214. PMID 8381111 DOI: 10.1002/Ijc.2910530206  0.396
1992 Lund-Johansen M, Forsberg K, Bjerkvig R, Laerum OD. Effects of growth factors on a human glioma cell line during invasion into rat brain aggregates in culture. Acta Neuropathologica. 84: 190-197. PMID 1523973 DOI: 10.1007/Bf00311394  0.465
1991 Andersson AM, Moran N, Gaardsvoll H, Linnemann D, Bjerkvig R, Laerum OD, Bock E. Characterization of NCAM expression and function in BT4C and BT4Cn glioma cells. International Journal of Cancer. 47: 124-9. PMID 1985868 DOI: 10.1002/Ijc.2910470122  0.422
1990 Bjerkvig R, Tønnesen A, Laerum OD, Backlund E. Multicellular tumor spheroids from human gliomas maintained in organ culture. Journal of Neurosurgery. 72: 463-475. PMID 2406382 DOI: 10.3171/Jns.1990.72.3.0463  0.45
1990 Mella O, Bjerkvig R, Schem B, Dahl O, Laerum OD. A cerebral glioma model for experimental therapy andin vivo invasion studies in syngeneic BD IX rats Journal of Neuro-Oncology. 9: 93-104. PMID 2262805 DOI: 10.1007/Bf02427829  0.482
1990 Rucklidge GJ, Lund-Johansen M, Milne G, Bjerkvig R. Isolation and characterization of a metalloproteinase secreted by rat glioma cells in serum-free culture Biochemical and Biophysical Research Communications. 172: 544-550. PMID 2241953 DOI: 10.1016/0006-291X(90)90707-T  0.31
1990 Engebraaten O, Bjerkvig R, Lund-Johansen M, Wester K, Pedersen PH, Mørk S, Backlund EO, Laerum OD. Interaction between human brain tumour biopsies and fetal rat brain tissue in vitro. Acta Neuropathologica. 81: 130-140. PMID 2082653 DOI: 10.1007/Bf00334501  0.389
1990 Laerum OD, Bjerkvig R. Monolayer and Three-Dimensional Culture of Rat and Human Central Nervous System: Normal and Malignant Cells and Their Interactions Methods in Neurosciences. 2: 210-236. DOI: 10.1016/B978-0-12-185254-2.50019-X  0.409
1988 Bjerknes R, Ødegaard S, Bjerkvig R, Børkje B, Lærum OD. Whipple's disease. Demonstration of a persisting monocyte and macrophage dysfunction. Scandinavian Journal of Gastroenterology. 23: 611-619. PMID 2456603 DOI: 10.3109/00365528809093921  0.574
1987 Male R, Bjerkvig R, Lillehaug JR. Biological and biochemical characterization of cell lines derived from initiation-promotion transformed C3H/10T1/2 cells. Carcinogenesis. 8: 1375-1383. PMID 3652375 DOI: 10.1093/Carcin/8.10.1375  0.439
1987 Bjerknes R, Bjerkvig R, Laerum OD. Phagocytic Capacity of Normal and Malignant Rat Glial Cells in Culture Journal of the National Cancer Institute. 78: 279-288. DOI: 10.1093/Jnci/78.2.279  0.417
1986 Bjerkvig R. Reaggregation of fetal rat brain cells in a stationary culture system II: Ultrastructural characterization In Vitro Cellular & Developmental Biology – Plant. 22: 193-200. PMID 3700322 DOI: 10.1007/Bf02623303  0.337
1986 Bjerkvig R, Steinsvåg SK, Laerum OD. Reaggregation of fetal rat brain cells in a stationary culture system. I: Methodology and cell identification. In Vitro Cellular & Developmental Biology – Plant. 22: 180-192. PMID 3516971 DOI: 10.1007/Bf02623302  0.355
1985 Bigner SH, Bjerkvig R, Laerum OD. DNA content and chromosomal composition of malignant human gliomas. Neurologic Clinics. 3: 769-84. PMID 3001489 DOI: 10.1016/S0733-8619(18)31008-9  0.332
1985 Steinsvåg SK, Laerum OD, Bjerkvig R. Interaction Between Rat Glioma Cells and Normal Rat Brain Tissue in Organ Culture Journal of the National Cancer Institute. 74: 1095-1104. DOI: 10.1093/Jnci/74.5.1095  0.453
1984 Laerum OD, Bjerkvig R, Steinsvåg SK, Ridder Ld. Invasiveness of primary brain tumors. Cancer and Metastasis Reviews. 3: 223-236. PMID 6388824 DOI: 10.1007/Bf00048386  0.479
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