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Year Citation  Score
2020 Zhang H, Qi L, Du Y, Huang LF, Braun FK, Kogiso M, Zhao Y, Li C, Lindsay H, Zhao S, Injac SG, Baxter PA, Su JM, Stephan C, Keller C, et al. Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma. Cancers. 12. PMID 32517016 DOI: 10.3390/Cancers12061478  0.34
2020 Harrold AP, Cleary MM, Bharathy N, Lathara M, Berlow NE, Foreman NK, Donson AM, Amani V, Zuercher WJ, Keller C. In vitro benchmarking of NF-κB inhibitors. European Journal of Pharmacology. 172981. PMID 32014486 DOI: 10.1016/J.Ejphar.2020.172981  0.668
2019 Kats D, Ricker CA, Berlow NE, Noblet B, Nicolle D, Mevel K, Branchereau S, Judde JG, Stiverson CD, Stiverson CL, Svalina MN, Settelmeyer T, Matlock K, Lathara M, Mussini C, ... ... Keller C, et al. Volasertib preclinical activity in high-risk hepatoblastoma. Oncotarget. 10: 6403-6417. PMID 31741706 DOI: 10.18632/Oncotarget.27237  0.354
2019 Yohe ME, Heske CM, Stewart E, Adamson PC, Ahmed N, Antonescu CR, Chen E, Collins N, Ehrlich A, Galindo RL, Gryder BE, Hahn H, Hammond S, Hatley ME, Hawkins DS, ... ... Keller C, et al. Insights into pediatric rhabdomyosarcoma research: Challenges and goals. Pediatric Blood & Cancer. e27869. PMID 31222885 DOI: 10.1002/Pbc.27869  0.326
2019 Berlow NE, Rikhi R, Geltzeiler M, Abraham J, Svalina MN, Davis LE, Wise E, Mancini M, Noujaim J, Mansoor A, Quist MJ, Matlock KL, Goros MW, Hernandez BS, Doung YC, ... ... Keller C, et al. Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma. Bmc Cancer. 19: 593. PMID 31208434 DOI: 10.1186/S12885-019-5681-6  0.316
2019 Bharathy N, Berlow NE, Wang E, Abraham J, Settelmeyer TP, Hooper JE, Svalina MN, Bajwa Z, Goros MW, Hernandez BS, Wolff JE, Pal R, Davies AM, Ashok A, Bushby D, ... ... Keller C, et al. Preclinical rationale for entinostat in embryonal rhabdomyosarcoma. Skeletal Muscle. 9: 12. PMID 31113472 DOI: 10.1186/S13395-019-0198-X  0.389
2019 Wei Q, Ramsey SA, Larson MK, Berlow NE, Ochola D, Shiprack C, Kashyap A, Séguin B, Keller C, Löhr CV. Elucidating the transcriptional program of feline injection-site sarcoma using a cross-species mRNA-sequencing approach. Bmc Cancer. 19: 311. PMID 30947707 DOI: 10.1186/S12885-019-5501-Z  0.315
2019 Zhang H, Qi L, Du Y, Braun F, Kogiso M, Huang L, Klisch T, Zhao Y, Guo L, Li C, Zhao S, Lindsay HB, Injac S, Baxter P, Su J, ... ... Keller C, et al. TMOD-21. TARGETING ANAPLASTIC MENINGIOMA WITH PANOBINOSTAT IN PATIENT-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS DERIVED FROM A MATCHING PAIR OF PRIMARY AND RECURRENT TUMORS Neuro-Oncology. 21: vi267-vi267. DOI: 10.1093/Neuonc/Noz175.1120  0.385
2018 Bharathy N, Berlow NE, Wang E, Abraham J, Settelmeyer TP, Hooper JE, Svalina MN, Ishikawa Y, Zientek K, Bajwa Z, Goros MW, Hernandez BS, Wolff JE, Rudek MA, Xu L, ... ... Keller C, et al. The HDAC3-SMARCA4-miR-27a axis promotes expression of the fusion oncogene in rhabdomyosarcoma. Science Signaling. 11. PMID 30459282 DOI: 10.1126/Scisignal.Aau7632  0.678
2018 Malempati S, Chang BH, Reid JM, Liu X, Minard CG, Keller C, Fox E, Weigel B. ADVL1513: Results of a phase 1 trial of entinostat, an oral histone deacetylase inhibitor, in pediatric patients with recurrent or refractory solid tumors. Journal of Clinical Oncology. 36: 10556-10556. DOI: 10.1200/Jco.2018.36.15_Suppl.10556  0.336
2018 Cairo S, Noblet B, Rasmussen S, Svalina MN, Mevel K, Ven EL, Nicolle D, Déas O, Mussini C, Branchereau S, Judde J, Keller C. Abstract 4628: Tailoring personalized strategies for children with treatment-refractory liver cancer Cancer Research. 78: 4628-4628. DOI: 10.1158/1538-7445.Am2018-4628  0.394
2017 Davis LE, Jeng S, Svalina MN, Huang E, Pittsenbarger J, Cantor EL, Berlow N, Seguin B, Mansoor A, McWeeney SK, Keller C. Integration of genomic, transcriptomic and functional profiles of aggressive osteosarcomas across multiple species. Oncotarget. 8: 76241-76256. PMID 29100308 DOI: 10.18632/Oncotarget.19532  0.391
2017 Bharathy N, Svalina MN, Settelmeyer TP, Cleary MM, Berlow NE, Airhart SD, Xiang S, Keck J, Hayden JB, Shern JF, Mansoor A, Lathara M, Srinivasa G, Langenau DM, Keller C. Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma. Oncotarget. 8: 62976-62983. PMID 28968964 DOI: 10.18632/Oncotarget.18520  0.375
2017 Cleary MM, Mansoor A, Settelmeyer T, Ijiri Y, Ladner KJ, Svalina MN, Rubin BP, Guttridge DC, Keller C. NFκB signaling in alveolar rhabdomyosarcoma. Disease Models & Mechanisms. 10: 1109-1115. PMID 28883017 DOI: 10.1242/Dmm.030882  0.457
2017 Randolph ME, Cleary MM, Bajwa Z, Svalina MN, Young MC, Mansoor A, Kaur P, Bult CJ, Goros MW, Michalek JE, Xiang S, Keck J, Krasnoperov V, Gill P, Keller C. EphB4/EphrinB2 therapeutics in Rhabdomyosarcoma. Plos One. 12: e0183161. PMID 28817624 DOI: 10.1371/Journal.Pone.0183161  0.377
2017 Ignatius MS, Hayes MN, Lobbardi R, Chen EY, McCarthy KM, Sreenivas P, Motala Z, Durbin AD, Molodtsov A, Reeder S, Jin A, Sindiri S, Beleyea BC, Bhere D, Alexander MS, ... ... Keller C, et al. The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma. Cell Reports. 19: 2304-2318. PMID 28614716 DOI: 10.1016/J.Celrep.2017.05.061  0.362
2017 Matlock K, Berlow N, Keller C, Pal R. Combination therapy design for maximizing sensitivity and minimizing toxicity. Bmc Bioinformatics. 18: 116. PMID 28361667 DOI: 10.1186/S12859-017-1523-1  0.343
2016 Ricker CA, Pan Y, Gutmann DH, Keller C. Challenges in Drug Discovery for Neurofibromatosis Type 1-Associated Low-Grade Glioma. Frontiers in Oncology. 6: 259. PMID 28066715 DOI: 10.3389/Fonc.2016.00259  0.385
2016 Svalina MN, Kikuchi K, Abraham J, Lal S, Davare MA, Settelmeyer TP, Young MC, Peckham JL, Cho YJ, Michalek JE, Hernandez BS, Berlow NE, Jackson M, Guillaume DJ, Selden NR, ... ... Keller C, et al. IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma. Scientific Reports. 6: 27012. PMID 27255663 DOI: 10.1038/Srep27012  0.314
2015 Hooper JE, Cantor EL, Ehlen MS, Banerjee A, Malempati S, Stenzel P, Woltjer RL, Gandour-Edwards R, Goodwin NC, Yang Y, Kaur P, Bult CJ, Airhart SD, Keller C. A Patient-Derived Xenograft Model of Parameningeal Embryonal Rhabdomyosarcoma for Preclinical Studies. Sarcoma. 2015: 826124. PMID 26696773 DOI: 10.1155/2015/826124  0.376
2015 Zhu B, Zhang M, Williams EM, Keller C, Mansoor A, Davie JK. TBX2 represses PTEN in rhabdomyosarcoma and skeletal muscle. Oncogene. PMID 26686089 DOI: 10.1038/Onc.2015.486  0.428
2015 Noujaim J, Thway K, Sheri A, Keller C, Jones RL. Histology-Driven Therapy: The Importance of Diagnostic Accuracy in Guiding Systemic Therapy of Soft Tissue Tumors. International Journal of Surgical Pathology. PMID 26399578 DOI: 10.1177/1066896915606971  0.308
2015 Noujaim J, Thway K, Bajwa Z, Bajwa A, Maki RG, Jones RL, Keller C. Epithelioid Sarcoma: Opportunities for Biology-Driven Targeted Therapy. Frontiers in Oncology. 5: 186. PMID 26347853 DOI: 10.3389/Fonc.2015.00186  0.303
2015 Faggi F, Codenotti S, Poliani PL, Cominelli M, Chiarelli N, Colombi M, Vezzoli M, Monti E, Bono F, Tulipano G, Fiorentini C, Zanola A, Lo HP, Parton RG, Keller C, et al. MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line. Plos One. 10: e0130287. PMID 26086601 DOI: 10.1371/Journal.Pone.0130287  0.385
2015 Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, ... ... Keller C, et al. Functionally defined therapeutic targets in diffuse intrinsic pontine glioma. Nature Medicine. 21: 555-9. PMID 25939062 DOI: 10.1038/Nm.3855  0.339
2015 Geltzeiler M, Li G, Abraham J, Keller C. The case for primary salivary rhabdomyosarcoma. Frontiers in Oncology. 5: 74. PMID 25883905 DOI: 10.3389/Fonc.2015.00074  0.41
2015 Faggi F, Chiarelli N, Colombi M, Mitola S, Ronca R, Madaro L, Bouche M, Poliani PL, Vezzoli M, Longhena F, Monti E, Salani B, Maggi D, Keller C, Fanzani A. Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 95: 585-602. PMID 25822667 DOI: 10.1038/Labinvest.2015.45  0.387
2015 Svalina MN, Kikuchi K, Abraham J, Lal S, Davare MA, Peckham JL, Cho Y, Jackson M, Guillaume DJ, Selden NR, Bigner DD, Nazemi KJ, Green SC, Corless CL, Gultekin S, ... ... Keller C, et al. Abstract A08: IGF1R as a key target in high risk, metastatic medulloblastoma Brain. 75. DOI: 10.1158/1538-7445.Brain15-A08  0.393
2015 Ignatius M, Lobbardi R, Hayes M, Chen E, McCarthy K, Nielsen GP, Beleyea B, Linardic C, Khan J, Keller C, Langenau DM. Abstract 4733: Notch signaling increases the number of relapse-driving tumor propagating cells in embryonal rhabdomyosarcoma Cancer Research. 75: 4733-4733. DOI: 10.1158/1538-7445.Am2015-4733  0.411
2015 Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily M, Quist MJ, Davis L, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung T, Sun W, Kogiso M, ... ... Keller C, et al. BT-02 * FUNCTIONALLY-DEFINED THERAPEUTIC TARGETS IN DIFFUSE INTRINSIC PONTINE GLIOMA Neuro-Oncology. 17: iii3-iii3. DOI: 10.1093/Neuonc/Nov061.12  0.36
2014 Berlow N, Haider S, Qian Wan, Geltzeiler M, Davis LE, Keller C, Pal R. An Integrated Approach to Anti-Cancer Drug Sensitivity Prediction. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 11: 995-1008. PMID 26357038 DOI: 10.1109/Tcbb.2014.2321138  0.33
2014 Hettmer S, Li Z, Billin AN, Barr FG, Cornelison DD, Ehrlich AR, Guttridge DC, Hayes-Jordan A, Helman LJ, Houghton PJ, Khan J, Langenau DM, Linardic CM, Pal R, Partridge TA, ... ... Keller C, et al. Rhabdomyosarcoma: current challenges and their implications for developing therapies. Cold Spring Harbor Perspectives in Medicine. 4: a025650. PMID 25368019 DOI: 10.1101/Cshperspect.A025650  0.38
2014 Svalina MN, Keller C. YAPping about differentiation therapy in muscle cancer. Cancer Cell. 26: 154-5. PMID 25117705 DOI: 10.1016/J.Ccr.2014.07.011  0.342
2014 Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, ... ... Keller C, et al. Lineage of origin in rhabdomyosarcoma informs pharmacological response. Genes & Development. 28: 1578-91. PMID 25030697 DOI: 10.1101/Gad.238733.114  0.612
2014 Davare MA, Lal S, Peckham JL, Prajapati SI, Gultekin SH, Rubin BP, Keller C. Secreted meningeal chemokines, but not VEGFA, modulate the migratory properties of medulloblastoma cells. Biochemical and Biophysical Research Communications. 450: 555-60. PMID 24928387 DOI: 10.1016/J.Bbrc.2014.06.018  0.326
2014 Aslam MI, Abraham J, Mansoor A, Druker BJ, Tyner JW, Keller C. PDGFRβ reverses EphB4 signaling in alveolar rhabdomyosarcoma. Proceedings of the National Academy of Sciences of the United States of America. 111: 6383-8. PMID 24733895 DOI: 10.1073/Pnas.1403608111  0.385
2014 Chen EY, DeRan MT, Ignatius MS, Grandinetti KB, Clagg R, McCarthy KM, Lobbardi RM, Brockmann J, Keller C, Wu X, Langenau DM. Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma. Proceedings of the National Academy of Sciences of the United States of America. 111: 5349-54. PMID 24706870 DOI: 10.1073/Pnas.1317731111  0.34
2014 Kikuchi K, Hettmer S, Aslam MI, Michalek JE, Laub W, Wilky BA, Loeb DM, Rubin BP, Wagers AJ, Keller C. Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma. Plos Genetics. 10: e1004107. PMID 24453992 DOI: 10.1371/Journal.Pgen.1004107  0.43
2014 Sokolowski E, Turina CB, Kikuchi K, Langenau DM, Keller C. Proof-of-concept rare cancers in drug development: the case for rhabdomyosarcoma. Oncogene. 33: 1877-89. PMID 23665679 DOI: 10.1038/Onc.2013.129  0.333
2013 Jothi M, Mal M, Keller C, Mal AK. Small molecule inhibition of PAX3-FOXO1 through AKT activation suppresses malignant phenotypes of alveolar rhabdomyosarcoma. Molecular Cancer Therapeutics. 12: 2663-74. PMID 24107448 DOI: 10.1158/1535-7163.Mct-13-0277  0.434
2013 He WA, Berardi E, Cardillo VM, Acharyya S, Aulino P, Thomas-Ahner J, Wang J, Bloomston M, Muscarella P, Nau P, Shah N, Butchbach ME, Ladner K, Adamo S, Rudnicki MA, ... Keller C, et al. NF-κB-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia. The Journal of Clinical Investigation. 123: 4821-35. PMID 24084740 DOI: 10.1172/Jci68523  0.362
2013 Chen EY, Dobrinski KP, Brown KH, Clagg R, Edelman E, Ignatius MS, Chen JY, Brockmann J, Nielsen GP, Ramaswamy S, Keller C, Lee C, Langenau DM. Cross-species array comparative genomic hybridization identifies novel oncogenic events in zebrafish and human embryonal rhabdomyosarcoma. Plos Genetics. 9: e1003727. PMID 24009521 DOI: 10.1371/Journal.Pgen.1003727  0.36
2013 Aslam MI, Hettmer S, Abraham J, Latocha D, Soundararajan A, Huang ET, Goros MW, Michalek JE, Wang S, Mansoor A, Druker BJ, Wagers AJ, Tyner JW, Keller C. Dynamic and nuclear expression of PDGFRα and IGF-1R in alveolar Rhabdomyosarcoma. Molecular Cancer Research : McR. 11: 1303-13. PMID 23928059 DOI: 10.1158/1541-7786.Mcr-12-0598  0.307
2013 Balkhi MY, Balkhi MY, Iwenofu OH, Bakkar N, Ladner KJ, Chandler DS, Houghton PJ, London CA, Kraybill W, Perrotti D, Croce CM, Keller C, Guttridge DC. miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR. Science Signaling. 6: ra63. PMID 23901138 DOI: 10.1126/Scisignal.2004177  0.337
2013 Li G, Kikuchi K, Radka M, Abraham J, Rubin BP, Keller C. IL-4 receptor blockade abrogates satellite cell: rhabdomyosarcoma fusion and prevents tumor establishment. Stem Cells (Dayton, Ohio). 31: 2304-12. PMID 23897781 DOI: 10.1002/Stem.1491  0.399
2013 Berlow N, Davis LE, Cantor EL, Séguin B, Keller C, Pal R. A new approach for prediction of tumor sensitivity to targeted drugs based on functional data. Bmc Bioinformatics. 14: 239. PMID 23890326 DOI: 10.1186/1471-2105-14-239  0.326
2013 Keller C, Guttridge DC. Mechanisms of impaired differentiation in rhabdomyosarcoma. The Febs Journal. 280: 4323-34. PMID 23822136 DOI: 10.1111/Febs.12421  0.408
2013 Kikuchi K, Wettach GR, Ryan CW, Hung A, Hooper JE, Beadling C, Warrick A, Corless CL, Olson SB, Keller C, Mansoor A. MDM2 Amplification and PI3KCA Mutation in a Case of Sclerosing Rhabdomyosarcoma. Sarcoma. 2013: 520858. PMID 23766666 DOI: 10.1155/2013/520858  0.337
2013 Biressi S, Bjornson CR, Carlig PM, Nishijo K, Keller C, Rando TA. Myf5 expression during fetal myogenesis defines the developmental progenitors of adult satellite cells. Developmental Biology. 379: 195-207. PMID 23639729 DOI: 10.1016/J.Ydbio.2013.04.021  0.332
2013 Lin S, Shen H, Jin B, Gu Y, Chen Z, Cao C, Hu C, Keller C, Pear WS, Wu L. Brief report: Blockade of Notch signaling in muscle stem cells causes muscular dystrophic phenotype and impaired muscle regeneration. Stem Cells (Dayton, Ohio). 31: 823-8. PMID 23307608 DOI: 10.1002/Stem.1319  0.324
2013 Alabran JL, Hooper JE, Hill M, Smith SE, Spady KK, Davis LE, Peterson LS, Malempati S, Ryan CW, Acosta R, Spunt SL, Keller C. Overcoming autopsy barriers in pediatric cancer research. Pediatric Blood & Cancer. 60: 204-9. PMID 23015377 DOI: 10.1002/Pbc.24320  0.324
2013 Kikuchi K, Soundararajan A, Zarzabal LA, Weems CR, Nelon LD, Hampton ST, Michalek JE, Rubin BP, Fields AP, Keller C. Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma. Oncogene. 32: 286-95. PMID 22349825 DOI: 10.1038/Onc.2012.46  0.441
2013 Geltzeiler MN, Andersen PE, Gross ND, Cantor EL, Berlow N, Pal R, Keller C. Personalized Cancer Care for Head and Neck Squamous Cell Carcinoma Otolaryngology–Head and Neck Surgery. 149: P184-P184. DOI: 10.1177/0194599813496044A127  0.355
2013 Kikuchi K, Hettmer S, Aslam MI, Michalek JE, Laub W, Rubin BP, Wagers AJ, Keller C. Abstract 1747: The Pax3:Foxo1a translocation product is a cell cycle-specific modifier of the alveolar rhabdomyosarcoma tumor phenotype. Cancer Research. 73: 1747-1747. DOI: 10.1158/1538-7445.Am2013-1747  0.346
2013 Chen E, Dobrinski KP, Brown KH, Clagg R, Edelman E, Ignatius M, Brockmann J, Nielsen GP, Ramaswamy S, Keller C, Lee C, Langenau DM. Abstract 1412: Cross-species array comparative genomic hybridization identifies novel driver genes in embryonal rhabdomyosarcoma. Cancer Research. 73: 1412-1412. DOI: 10.1158/1538-7445.Am2013-1412  0.367
2013 Balkhi MY, Iwenofu OH, Bakkar N, Ladner KJ, Chandler DS, Houghton PJ, London CA, Kraybill W, Perrotti D, Croce CM, Keller C, Guttridge DC. Erratum: miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR (Science Signaling (2013) 6 (er6)) Science Signaling. 6. DOI: 10.1126/Scisignal.292Er6  0.328
2012 Kikuchi K, Keller C. The not-so-skinny on muscle cancer. Cancer Cell. 22: 421-2. PMID 23079652 DOI: 10.1016/J.Ccr.2012.09.018  0.323
2012 Marchildon F, Lala N, Li G, St-Louis C, Lamothe D, Keller C, Wiper-Bergeron N. CCAAT/enhancer binding protein beta is expressed in satellite cells and controls myogenesis. Stem Cells (Dayton, Ohio). 30: 2619-30. PMID 23034923 DOI: 10.1002/Stem.1248  0.35
2012 Abraham J, Chua YX, Glover JM, Tyner JW, Loriaux MM, Kilcoyne A, Giles FJ, Nelon LD, Carew JS, Ouyang Y, Michalek JE, Pal R, Druker BJ, Rubin BP, Keller C. An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma. Biochemical and Biophysical Research Communications. 426: 363-8. PMID 22960170 DOI: 10.1016/J.Bbrc.2012.08.092  0.405
2012 Wen Y, Bi P, Liu W, Asakura A, Keller C, Kuang S. Constitutive Notch activation upregulates Pax7 and promotes the self-renewal of skeletal muscle satellite cells. Molecular and Cellular Biology. 32: 2300-11. PMID 22493066 DOI: 10.1128/Mcb.06753-11  0.374
2012 Jothi M, Nishijo K, Keller C, Mal AK. AKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cell. Cell Cycle (Georgetown, Tex.). 11: 895-908. PMID 22333587 DOI: 10.4161/Cc.11.5.19346  0.369
2012 Ohshima-Hosoyama S, Davare MA, Prajapati SI, Abraham J, Lal S, Nelon LD, Kilcoyne A, Giles FJ, Hanes MA, Rubin BP, Keller C. Preclinical testing of tandutinib in a transgenic medulloblastoma mouse model. Journal of Pediatric Hematology/Oncology. 34: 116-21. PMID 22146535 DOI: 10.1097/Mph.0B013E3182309Fe4  0.392
2012 Spunt SL, Vargas SO, Coffin CM, Skapek SX, Parham DM, Darling J, Hawkins DS, Keller C. The clinical, research, and social value of autopsy after any cancer death: a perspective from the Children's Oncology Group Soft Tissue Sarcoma Committee. Cancer. 118: 3002-9. PMID 22006470 DOI: 10.1002/Cncr.26620  0.356
2012 Londhe P, Zhu B, Abraham J, Keller C, Davie J. CIITA is silenced by epigenetic mechanisms that prevent the recruitment of transactivating factors in rhabdomyosarcoma cells. International Journal of Cancer. Journal International Du Cancer. 131: E437-48. PMID 21989738 DOI: 10.1002/Ijc.26478  0.344
2011 Amini-Nik S, Glancy D, Boimer C, Whetstone H, Keller C, Alman BA. Pax7 expressing cells contribute to dermal wound repair, regulating scar size through a β-catenin mediated process. Stem Cells (Dayton, Ohio). 29: 1371-9. PMID 21739529 DOI: 10.1002/Stem.688  0.301
2011 Ohshima-Hosoyama S, Davare MA, Hosoyama T, Nelon LD, Keller C. Bortezomib stabilizes NOXA and triggers ROS-associated apoptosis in medulloblastoma. Journal of Neuro-Oncology. 105: 475-83. PMID 21633906 DOI: 10.1007/S11060-011-0619-0  0.339
2011 Kikuchi K, Rubin BP, Keller C. Developmental origins of fusion-negative rhabdomyosarcomas. Current Topics in Developmental Biology. 96: 33-56. PMID 21621066 DOI: 10.1016/B978-0-12-385940-2.00002-4  0.369
2011 Abraham J, Nelon LD, Kubicek CB, Kilcoyne A, Hampton ST, Zarzabal LA, Giles FJ, Michalek JE, Rubin BP, Keller C. Preclinical testing of erlotinib in a transgenic alveolar rhabdomyosarcoma mouse model. Sarcoma. 2011: 130484. PMID 21559212 DOI: 10.1155/2011/130484  0.366
2011 Hosoyama T, Aslam MI, Abraham J, Prajapati SI, Nishijo K, Michalek JE, Zarzabal LA, Nelon LD, Guttridge DC, Rubin BP, Keller C. IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2757-66. PMID 21536546 DOI: 10.1158/1078-0432.Ccr-10-3445  0.31
2011 Hosoyama T, Nishijo K, Prajapati SI, Li G, Keller C. Rb1 gene inactivation expands satellite cell and postnatal myoblast pools. The Journal of Biological Chemistry. 286: 19556-64. PMID 21478154 DOI: 10.1074/Jbc.M111.229542  0.345
2011 Abraham J, Prajapati SI, Nishijo K, Schaffer BS, Taniguchi E, Kilcoyne A, McCleish AT, Nelon LD, Giles FG, Efstratiadis A, LeGallo RD, Nowak BM, Rubin BP, Malempati S, Keller C. Evasion mechanisms to Igf1r inhibition in rhabdomyosarcoma. Molecular Cancer Therapeutics. 10: 697-707. PMID 21447712 DOI: 10.1158/1535-7163.Mct-10-0695  0.382
2011 Watanabe S, Hirai H, Asakura Y, Tastad C, Verma M, Keller C, Dutton JR, Asakura A. MyoD gene suppression by Oct4 is required for reprogramming in myoblasts to produce induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 29: 505-16. PMID 21425413 DOI: 10.1002/Stem.598  0.362
2011 Rubin BP, Nishijo K, Chen HI, Yi X, Schuetze DP, Pal R, Prajapati SI, Abraham J, Arenkiel BR, Chen QR, Davis S, McCleish AT, Capecchi MR, Michalek JE, Zarzabal LA, ... ... Keller C, et al. Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma. Cancer Cell. 19: 177-91. PMID 21316601 DOI: 10.1016/J.Ccr.2010.12.023  0.562
2011 Kikuchi K, Soundararajan A, Zarzabal LA, Weems CR, Nelson LD, Hampton ST, Michalek JA, Rubin BP, Fields AP, Keller C. Abstract 1043: Role of protein kinase Cι in alveolar rhabdomyosarcoma Cancer Research. 71: 1043-1043. DOI: 10.1158/1538-7445.Am2011-1043  0.422
2010 Hosoyama T, Nishijo K, Garcia MM, Schaffer BS, Ohshima-Hosoyama S, Prajapati SI, Davis MD, Grant WF, Scheithauer BW, Marks DL, Rubin BP, Keller C. A Postnatal Pax7 Progenitor Gives Rise to Pituitary Adenomas. Genes & Cancer. 1: 388-402. PMID 20811506 DOI: 10.1177/1947601910370979  0.336
2010 Ohshima-Hosoyama S, Hosoyama T, Nelon LD, Keller C. IGF-1 receptor inhibition by picropodophyllin in medulloblastoma. Biochemical and Biophysical Research Communications. 399: 727-32. PMID 20692232 DOI: 10.1016/J.Bbrc.2010.08.009  0.379
2010 Schaffer BS, Grayson MH, Wortham JM, Kubicek CB, McCleish AT, Prajapati SI, Nelon LD, Brady MM, Jung I, Hosoyama T, Sarro LM, Hanes MA, Rubin BP, Michalek JE, Clifford CB, ... ... Keller C, et al. Immune competency of a hairless mouse strain for improved preclinical studies in genetically engineered mice. Molecular Cancer Therapeutics. 9: 2354-64. PMID 20663932 DOI: 10.1158/1535-7163.Mct-10-0207  0.326
2010 Prajapati SI, Martinez CO, Abraham J, McCleish AT, Michalek JE, McManus LM, Rubin BP, Shireman PK, Keller C. Crimson carrier, a long-acting contrast agent for in vivo near-infrared imaging of injured and diseased muscle. Muscle & Nerve. 42: 245-51. PMID 20544935 DOI: 10.1002/Mus.21682  0.305
2010 Shea KL, Xiang W, LaPorta VS, Licht JD, Keller C, Basson MA, Brack AS. Sprouty1 regulates reversible quiescence of a self-renewing adult muscle stem cell pool during regeneration. Cell Stem Cell. 6: 117-29. PMID 20144785 DOI: 10.1016/J.Stem.2009.12.015  0.327
2010 Samano AK, Ohshima-Hosoyama S, Whitney TG, Prajapati SI, Kilcoyne A, Taniguchi E, Morgan WW, Nelon LD, Lin AL, Togao O, Jung I, Rubin BP, Nowak BM, Duong TQ, Keller C. Functional evaluation of therapeutic response for a mouse model of medulloblastoma. Transgenic Research. 19: 829-40. PMID 20107895 DOI: 10.1007/S11248-010-9361-1  0.324
2010 Jothi M, Keller C, Mal AK. Abstract LB-20: Transcriptionally inactive PAX3-FKHR fails to induce ARMS cells differentiation Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-20  0.387
2009 Brack AS, Murphy-Seiler F, Hanifi J, Deka J, Eyckerman S, Keller C, Aguet M, Rando TA. BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration. Developmental Biology. 335: 93-105. PMID 19699733 DOI: 10.1016/J.Ydbio.2009.08.014  0.328
2009 McDonald PC, Dedhar S, Keller C. Integrin-linked kinase: both Jekyll and Hyde in rhabdomyosarcoma. The Journal of Clinical Investigation. 119: 1452-5. PMID 19504719 DOI: 10.1172/Jci39457  0.337
2009 Quach NL, Biressi S, Reichardt LF, Keller C, Rando TA. Focal adhesion kinase signaling regulates the expression of caveolin 3 and beta1 integrin, genes essential for normal myoblast fusion. Molecular Biology of the Cell. 20: 3422-35. PMID 19458188 DOI: 10.1091/Mbc.E09-02-0175  0.373
2009 Nishijo K, Chen QR, Zhang L, McCleish AT, Rodriguez A, Cho MJ, Prajapati SI, Gelfond JA, Chisholm GB, Michalek JE, Aronow BJ, Barr FG, Randall RL, Ladanyi M, Qualman SJ, ... ... Keller C, et al. Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma. Cancer Research. 69: 2902-11. PMID 19339268 DOI: 10.1158/0008-5472.Can-08-3723  0.391
2009 Nishijo K, Hosoyama T, Bjornson CR, Schaffer BS, Prajapati SI, Bahadur AN, Hansen MS, Blandford MC, McCleish AT, Rubin BP, Epstein JA, Rando TA, Capecchi MR, Keller C. Biomarker system for studying muscle, stem cells, and cancer in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2681-90. PMID 19332644 DOI: 10.1096/Fj.08-128116  0.585
2009 Taniguchi E, Cho MJ, Arenkiel BR, Hansen MS, Rivera OJ, McCleish AT, Qualman SJ, Guttridge DC, Scott MP, Capecchi MR, Keller C. Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma. Pediatric Blood & Cancer. 53: 136-44. PMID 19213072 DOI: 10.1002/Pbc.21968  0.602
2008 Taniguchi E, Nishijo K, McCleish AT, Michalek JE, Grayson MH, Infante AJ, Abboud HE, Legallo RD, Qualman SJ, Rubin BP, Keller C. PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma. Oncogene. 27: 6550-60. PMID 18679424 DOI: 10.1038/Onc.2008.255  0.431
2008 Vasquez SX, Hansen MS, Bahadur AN, Hockin MF, Kindlmann GL, Nevell L, Wu IQ, Grunwald DJ, Weinstein DM, Jones GM, Johnson CR, Vandeberg JL, Capecchi MR, Keller C. Optimization of volumetric computed tomography for skeletal analysis of model genetic organisms. Anatomical Record (Hoboken, N.J. : 2007). 291: 475-87. PMID 18286615 DOI: 10.1002/Ar.20670  0.501
2007 Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, Rando TA. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science (New York, N.Y.). 317: 807-10. PMID 17690295 DOI: 10.1126/Science.1144090  0.302
2006 Johnson JT, Hansen MS, Wu I, Healy LJ, Johnson CR, Jones GM, Capecchi MR, Keller C. Virtual histology of transgenic mouse embryos for high-throughput phenotyping. Plos Genetics. 2: e61. PMID 16683035 DOI: 10.1371/Journal.Pgen.0020061  0.501
2005 Kindlmann GL, Weinstein DM, Jones GM, Johnson CR, Capecchi MR, Keller C. Practical vessel imaging by computed tomography in live transgenic mouse models for human tumors. Molecular Imaging. 4: 417-24. PMID 16285903 DOI: 10.2310/7290.2005.05166  0.536
2005 Keller C, Capecchi MR. New genetic tactics to model alveolar rhabdomyosarcoma in the mouse. Cancer Research. 65: 7530-2. PMID 16140913 DOI: 10.1158/0008-5472.Can-05-0477  0.577
2004 Keller C, Hansen MS, Coffin CM, Capecchi MR. Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. Genes & Development. 18: 2608-13. PMID 15520281 DOI: 10.1101/Gad.1243904  0.59
2004 Keller C, Arenkiel BR, Coffin CM, El-Bardeesy N, DePinho RA, Capecchi MR. Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. Genes & Development. 18: 2614-26. PMID 15489287 DOI: 10.1101/Gad.1244004  0.587
Low-probability matches (unlikely to be authored by this person)
2013 Hsiao TH, Chen HI, Lu JY, Lin PY, Keller C, Comerford S, Tomlinson GE, Chen Y. Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma. Translational Cancer Research. 2: 6-17. PMID 23905013 DOI: 10.3978/J.Issn.2218-676X.2012.12.04  0.3
2015 Milovancev M, Hauck M, Keller C, Stranahan LW, Mansoor A, Malarkey DE. Comparative pathology of canine soft tissue sarcomas: possible models of human non-rhabdomyosarcoma soft tissue sarcomas. Journal of Comparative Pathology. 152: 22-7. PMID 25435513 DOI: 10.1016/J.Jcpa.2014.09.005  0.298
2013 Davis LE, Hofmann NE, Li G, Huang ET, Loriaux MM, Bracha S, Helfand SC, Mata JE, Marley K, Mansoor A, Tyner JW, Abraham J, Séguin B, Keller C. A case study of personalized therapy for osteosarcoma. Pediatric Blood & Cancer. 60: 1313-9. PMID 23526721 DOI: 10.1002/Pbc.24512  0.297
2013 Kikuchi K, Taniguchi E, Chen HI, Svalina MN, Abraham J, Huang ET, Nishijo K, Davis S, Louden C, Zarzabal LA, Recht O, Bajwa A, Berlow N, Suelves M, Perkins SL, ... ... Keller C, et al. Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma. Skeletal Muscle. 3: 27. PMID 24274149 DOI: 10.1186/2044-5040-3-27  0.294
2014 Berlow N, Davis L, Keller C, Pal R. Inference of dynamic biological networks based on responses to drug perturbations. Eurasip Journal On Bioinformatics & Systems Biology. 2014: 14. PMID 28194164 DOI: 10.1186/S13637-014-0014-1  0.294
2022 Bharathy N, Cleary MM, Kim JA, Nagamori K, Crawford KA, Wang E, Saha D, Settelmeyer TP, Purohit R, Skopelitis D, Chang K, Doran JA, Kirschbaum CW, Bharathy S, Crews DW, ... ... Keller C, et al. SMARCA4 biology in alveolar rhabdomyosarcoma. Oncogene. PMID 35094009 DOI: 10.1038/s41388-022-02205-0  0.292
2011 McCarthy JJ, Mula J, Miyazaki M, Erfani R, Garrison K, Farooqui AB, Srikuea R, Lawson BA, Grimes B, Keller C, Van Zant G, Campbell KS, Esser KA, Dupont-Versteegden EE, Peterson CA. Effective fiber hypertrophy in satellite cell-depleted skeletal muscle. Development (Cambridge, England). 138: 3657-66. PMID 21828094 DOI: 10.1242/Dev.068858  0.284
2009 Prajapati SI, Martinez CO, Bahadur AN, Wu IQ, Zheng W, Lechleiter JD, McManus LM, Chisholm GB, Michalek JE, Shireman PK, Keller C. Near-infrared imaging of injured tissue in living subjects using IR-820. Molecular Imaging. 8: 45-54. PMID 19344575 DOI: 10.2310/7290.2009.00005  0.282
2004 Barnette P, Scholl R, Blandford M, Ballard L, Tsodikov A, Magee J, Williams S, Robertson M, Ali-Osman F, Lemons R, Keller C. High-throughput detection of glutathione s-transferase polymorphic alleles in a pediatric cancer population. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 13: 304-13. PMID 14973099 DOI: 10.1158/1055-9965.Epi-03-0178  0.281
2009 Pauws E, Hoshino A, Bentley L, Prajapati S, Keller C, Hammond P, Martinez-Barbera JP, Moore GE, Stanier P. Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes Human Molecular Genetics. 19: 4171-4179. DOI: 10.1093/Hmg/Ddq223  0.28
2012 Soundararajan A, Abraham J, Nelon LD, Prajapati SI, Zarzabal LA, Michalek JE, McHardy SF, Hawkins DS, Malempati S, Keller C. 18F-FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models. Pediatric Blood & Cancer. 59: 485-92. PMID 22238194 DOI: 10.1002/Pbc.24075  0.278
2011 Moore CM, Dick EJ, Hubbard GB, Gardner SM, Dunn BG, Brothman AR, Williams V, Prajapati SI, Keller C, Davis MD. Craniorachischisis and omphalocele in a stillborn cynomolgus monkey (Macaca fascicularis). American Journal of Medical Genetics. Part A. 155: 1367-73. PMID 21567905 DOI: 10.1002/Ajmg.A.33627  0.275
2011 Prajapati SI, Kilcoyne A, Samano AK, Green DP, McCarthy SD, Blackman BA, Brady MM, Zarzabal LA, Tatiparthy AK, Sledz TJ, Duong T, Ohshima-Hosoyama S, Giles FJ, Michalek JE, Rubin BP, ... Keller C, et al. MicroCT-based virtual histology evaluation of preclinical medulloblastoma. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 13: 493-9. PMID 20617390 DOI: 10.1007/S11307-010-0372-3  0.273
2006 Blandford MC, Barr FG, Lynch JC, Randall RL, Qualman SJ, Keller C. Rhabdomyosarcomas utilize developmental, myogenic growth factors for disease advantage: a report from the Children's Oncology Group. Pediatric Blood & Cancer. 46: 329-38. PMID 16261596 DOI: 10.1002/Pbc.20466  0.27
2010 Abraham J, Keller C. Renal stem cell biology starts to take spherical shape. Commentary on: Lusis et al., Isolation of clonogenic, long-term self renewing embryonic renal stem cells. Stem Cell Research. 5: 1-3. PMID 20541705 DOI: 10.1016/J.Scr.2010.05.002  0.269
2021 Lian X, Kats D, Rasmussen S, Martin LR, Karki A, Keller C, Berlow NE. Design considerations of an IL13Rα2 antibody-drug conjugate for diffuse intrinsic pontine glioma. Acta Neuropathologica Communications. 9: 88. PMID 34001278 DOI: 10.1186/s40478-021-01184-9  0.269
1997 Pati D, Keller C, Groudine M, Plon SE. Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA. Molecular and Cellular Biology. 17: 3037-46. PMID 9154802 DOI: 10.1128/Mcb.17.6.3037  0.266
2009 Martinez HG, Prajapati SI, Estrada CA, Jimenez F, Quinones MP, Wu I, Bahadur A, Sanderson A, Johnson CR, Shim M, Keller C, Ahuja SS. Images in cardiovascular medicine: Microscopic computed tomography-based virtual histology for visualization and morphometry of atherosclerosis in diabetic apolipoprotein e mutant mice. Circulation. 120: 821-2. PMID 19720948 DOI: 10.1161/Circulationaha.108.829531  0.266
2020 Crawford KA, Berlow NE, Tsay J, Lazich M, Mancini M, Noakes C, Huang T, Keller C. Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma. Cold Spring Harbor Molecular Case Studies. 6. PMID 32532875 DOI: 10.1101/mcs.a004853  0.264
2016 Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich MF, Lim R, Zimmermann B, Aspalter IM, Franco CA, Boettger T, Braun T, Fruttiger M, Rajewsky K, Keller C, Brüning JC, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. PMID 26735015 DOI: 10.1038/Nature16498  0.261
2015 Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, ... ... Keller C, et al. Erratum: Functionally defined therapeutic targets in diffuse intrinsic pontine glioma. Nature Medicine. 21: 827. PMID 26151328 DOI: 10.1038/Nm0715-827A  0.259
2019 Beltrán D, Anderson ME, Bharathy N, Settelmeyer TP, Svalina MN, Bajwa Z, Shern JF, Gultekin SH, Cuellar MA, Yonekawa T, Keller C, Campbell KP. Exogenous expression of the glycosyltransferase LARGE1 restores α-dystroglycan matriglycan and laminin binding in rhabdomyosarcoma. Skeletal Muscle. 9: 11. PMID 31054580 DOI: 10.1186/S13395-019-0195-0  0.255
2021 Regina C, Hamed E, Andrieux G, Angenendt S, Schneider M, Ku M, Follo M, Wachtel M, Ke E, Kikuchi K, Henssen AG, Schäfer BW, Boerries M, Wagers AJ, Keller C, et al. Negative correlation of single-cell expression with tumorigenicity in rhabdomyosarcoma. Life Science Alliance. 4. PMID 34187933 DOI: 10.26508/lsa.202001002  0.254
2011 Prajapati SI, Keller C. Contrast enhanced vessel imaging using microCT. Journal of Visualized Experiments : Jove. PMID 21307830 DOI: 10.3791/2377  0.253
2010 Zheng W, Watts LT, Holstein DM, Prajapati SI, Keller C, Grass EH, Walter CA, Lechleiter JD. Purinergic receptor stimulation reduces cytotoxic edema and brain infarcts in mouse induced by photothrombosis by energizing glial mitochondria. Plos One. 5: e14401. PMID 21203502 DOI: 10.1371/Journal.Pone.0014401  0.251
2017 Cates J, Nevell L, Prajapati SI, Nelon LD, Chang JY, Randolph ME, Wood B, Keller C, Whitaker RT. Shape analysis of the basioccipital bone in Pax7-deficient mice. Scientific Reports. 7: 17955. PMID 29263370 DOI: 10.1038/S41598-017-18199-9  0.25
2019 Armengol C, Kappler R, Zhu L, Timchenko N, Kats D, Keller C, Howard L, Grosset C, Nicolle D, Déas O, Pigazzi M, Brugières L, Mussini C, Galmiche-Rolland L, Chardot C, et al. Abstract 3107: A scientific task force to generate proof-of-concept data packages for clinical trials in pediatric cancers: The hepatoblastoma example Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3107  0.249
2013 Aaberg-Jessen C, Fogh L, Halle B, Jensen V, Brunner N, Kristensen BW, Abe T, Momii Y, Watanabe J, Morisaki I, Natsume A, Wakabayashi T, Fujiki M, Aldaz B, Fabius AWM, ... ... Keller C, et al. EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 15: iii37-iii61. DOI: 10.1093/Neuonc/Not176  0.246
2018 Berlow NE, Svalina MN, Quist MJ, Settelmeyer TP, Zherebitskiy V, Kogiso M, Qi L, Du Y, Hawkins CE, Hulleman E, Li XN, Gultekin SH, Keller C. IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma. Plos One. 13: e0193565. PMID 29621254 DOI: 10.1371/Journal.Pone.0193565  0.246
2023 Nakazawa K, Shaw T, Song YK, Kouassi-Brou M, Molotkova A, Tiwari PB, Chou HC, Wen X, Wei JS, Deniz E, Toretsky J, Keller C, Barr FG, Khan J, Üren A. Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity. Cancer Research Communications. PMID 37732905 DOI: 10.1158/2767-9764.CRC-23-0119  0.246
2021 Woods AD, Berlow NE, Ortiz MV, Dela Cruz F, Siddiquee A, Coutinho DF, Purohit R, Freier KET, Michalek JE, Lathara M, Matlock K, Srivivasa G, Royer-Pokora B, Veselska R, Kung AL, ... Keller C, et al. Bromodomain 4 inhibition leads to MYCN downregulation in Wilms tumor. Pediatric Blood & Cancer. e29401. PMID 34693628 DOI: 10.1002/pbc.29401  0.234
2016 Rikhi R, Wilson EM, Deas O, Svalina MN, Bial J, Mansoor A, Cairo S, Keller C. Murine model of hepatic breast cancer. Biochemistry and Biophysics Reports. 8: 1-5. PMID 28955934 DOI: 10.1016/J.Bbrep.2016.07.021  0.233
2007 Carney EW, Tornesi B, Keller C, Findlay HA, Nowland WS, Marshall VA, Ozolins TR. Refinement of a morphological scoring system for postimplantation rabbit conceptuses. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 80: 213-22. PMID 17570508 DOI: 10.1002/Bdrb.20118  0.233
2021 Lian X, Bond JS, Bharathy N, Boudko SP, Pokidysheva E, Shern JF, Lathara M, Sasaki T, Settelmeyer T, Cleary MM, Bajwa A, Srinivasa G, Hartley CP, Bächinger HP, Mansoor A, ... ... Keller C, et al. Defining the Extracellular Matrix of Rhabdomyosarcoma. Frontiers in Oncology. 11: 601957. PMID 33708626 DOI: 10.3389/fonc.2021.601957  0.232
2007 Vasquez SX, Bahadur AN, Johnson JT, Rodriguez DR, Keller C. Severe runting in a laboratory mouse (Mus musculus). Lab Animal. 36: 19, 22-3. PMID 17183339 DOI: 10.1038/Laban0107-19  0.225
1998 Shew SB, Kramer K, Keller C, Butte N, Plon SE, Jaksic T. Hypermetabolic Levels of Protein Turnover and Energy Expenditure in Bloom's Syndrome 735 Pediatric Research. 43: 128-128. DOI: 10.1203/00006450-199804001-00756  0.225
2014 Classen CF, William D, Linnebacher M, Farhod A, Kedr W, Elsabe B, Fadel S, Van Gool S, De Vleeschouwer S, Koks C, Garg A, Ehrhardt M, Riva M, De Vleeschouwer S, Agostinis P, ... ... Keller C, et al. HIGH GRADE GLIOMAS AND DIPG Neuro-Oncology. 16: i40-i59. DOI: 10.1093/Neuonc/Nou071  0.223
2012 Davis LE, Mori M, Keller C. Personalized cancer care: opportunities and challenges in pediatric neuro-oncology. Pediatric Blood & Cancer. 59: 1-2. PMID 22162198 DOI: 10.1002/Pbc.24018  0.223
2022 Karki A, Purohit R, Nosack S, Bharathy N, Michalek JE, Chen S, Keller C. Plexin-B2 and Semaphorins Do Not Drive Rhabdomyosarcoma Proliferation or Migration. Sarcoma. 2022: 9646909. PMID 35570846 DOI: 10.1155/2022/9646909  0.223
2017 Prajapati SI, Kilcoyne A, Samano AK, Green DP, McCarthy SD, Blackman BA, Brady MM, Zarzabal LA, Tatiparthi AK, Sledz TJ, Duong T, Ohshima-Hosoyama S, Giles FJ, Michalek JE, Rubin BP, ... Keller C, et al. Erratum to: MicroCT-Based Virtual Histology Evaluation of Preclinical Medulloblastoma. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 28389781 DOI: 10.1007/S11307-017-1079-5  0.222
2023 Chauhan S, Woods AD, Bharathy N, Lian X, Ricker CA, Mantz A, Zuercher WJ, Price LH, Morton MJ, Durrant E, Corbel SY, Sampath SC, Sampath SC, Joslin J, Keller C. Structure-activity relationship of dihydropyridines for rhabdomyosarcoma. Biochemical and Biophysical Research Communications. 667: 138-145. PMID 37224633 DOI: 10.1016/j.bbrc.2023.04.114  0.221
1999 Keller C, Keller KR, Shew SB, Plon SE. Growth deficiency and malnutrition in Bloom syndrome. The Journal of Pediatrics. 134: 472-479. PMID 10190923 DOI: 10.1016/S0022-3476(99)70206-4  0.217
2007 Bahadur AN, Wu IQ, Weinstein DM, Davis MD, Lewis DA, Kochunov P, Keller C. Multimodality Chamber for coregistered anatomical and molecular imaging of small animals. Lab Animal. 36: 29-35. PMID 17721530 DOI: 10.1038/Laban0907-29  0.217
2021 Cleary MM, Bharathy N, Abraham J, Kim JA, Rudzinski ER, Michalek JE, Keller C. Interleukin-4 Receptor Inhibition Targeting Metastasis Independent of Macrophages. Molecular Cancer Therapeutics. 20: 906-914. PMID 33853867 DOI: 10.1158/1535-7163.MCT-20-0199  0.216
2021 Berlow NE, Crawford K, Bult CJ, Noakes C, Sloma I, Rudzinski ER, Keller CJ. Functional impact of a germline RET mutation in alveolar rhabdomyosarcoma. Cold Spring Harbor Molecular Case Studies. PMID 33722797 DOI: 10.1101/mcs.a006049  0.216
2021 Karki A, Berlow NE, Kim JA, Hulleman E, Liu Q, Michalek JE, Keller C. Receptor-driven invasion profiles in diffuse intrinsic pontine glioma. Neuro-Oncology Advances. 3: vdab039. PMID 34013206 DOI: 10.1093/noajnl/vdab039  0.211
2004 Keller C, Gibbs CN, Kelly SM, Haller JR, White KS, Coffin CM, Lemons RS. Low-grade myofibrosarcoma of the head and neck: importance of surgical therapy. Journal of Pediatric Hematology/Oncology. 26: 119-20. PMID 14767203 DOI: 10.1097/00043426-200402000-00013  0.211
2012 Reichard JD, Kunz TH, Keller C, Prajapati SI. Vascular contrast enhanced micro-CT imaging of "radiators" in the Brazilian free-tailed bat (Tadarida brasiliensis). Anatomical Record (Hoboken, N.J. : 2007). 295: 563-6. PMID 22282439 DOI: 10.1002/Ar.22423  0.21
2023 Grünewald TGP, Postel-Vinay S, Nakayama RT, Berlow NE, Bolzicco A, Cerullo V, Dermawan JK, Frezza AM, Italiano A, Jin JX, Le Loarer F, Martín-Broto J, Pecora A, Perez-Martinez A, Tam YB, ... ... Keller C, et al. Translational Aspects of Epithelioid Sarcoma - Current Consensus. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37916971 DOI: 10.1158/1078-0432.CCR-23-2174  0.206
2010 Reichard JD, Prajapati SI, Austad SN, Keller C, Kunz TH. Thermal windows on Brazilian free-tailed bats facilitate thermoregulation during prolonged flight. Integrative and Comparative Biology. 50: 358-70. PMID 20811514 DOI: 10.1093/Icb/Icq033  0.204
2011 Huang E, Rubin BP, Keller C. The long road to immunotherapy for childhood rhabdomyosarcoma. Pediatric Blood & Cancer. 57: 899-901. PMID 21744478 DOI: 10.1002/Pbc.23136  0.203
2020 Ricker CA, Crawford K, Matlock K, Lathara M, Seguin B, Rudzinski ER, Berlow NE, Keller C. Defining an embryonal rhabdomyosarcoma endotype. Cold Spring Harbor Molecular Case Studies. 6. PMID 32238403 DOI: 10.1101/mcs.a005066  0.203
2000 Keller C, Langston C. Childhood Idiopathic Pulmonary Hemosiderosis The New England Journal of Medicine. 343: 781-781. PMID 10984566 DOI: 10.1056/Nejm200009143431105  0.201
2021 Woods AD, Purohit R, Mitchell L, Collier J, Collier K, Lathara M, Learned K, Vaske O, Geiger H, Wrzeszczynski KO, Jobanputra V, Srinivasa G, Rudzinski E, Whelan K, Beierle E, ... ... Keller C, et al. Metastatic Pediatric Sclerosing Epithelioid Fibrosarcoma. Cold Spring Harbor Molecular Case Studies. PMID 34362827 DOI: 10.1101/mcs.a006093  0.2
2017 Griger J, Schneider R, Lahmann I, Schöwel V, Keller C, Spuler S, Nazaré M, Birchmeier C. Loss of Ptpn11 (Shp2) drives satellite cells into quiescence. Elife. 6. PMID 28463680 DOI: 10.7554/eLife.21552  0.2
1996 Keller C, Kirkpatrick S, Lee K, Paul M, Hanson IC, Gilger M. Disseminated mycobacterium Avium Complex Presenting As Hematochezia In An Infant With Rapidly Progressive Acquired Immunodeficiency Syndrome Pediatric Infectious Disease Journal. 15: 713-715. PMID 8858681 DOI: 10.1097/00006454-199608000-00020  0.2
2020 Berlow NE, Grasso CS, Quist MJ, Cheng M, Gandour-Edwards R, Hernandez BS, Michalek JE, Ryan C, Spellman P, Pal R, Million LS, Renneker M, Keller C. Deep Functional and Molecular Characterization of a High-Risk Undifferentiated Pleomorphic Sarcoma. Sarcoma. 2020: 6312480. PMID 32565715 DOI: 10.1155/2020/6312480  0.193
2021 Rasmussen SV, Berlow NE, Price LH, Mansoor A, Cairo S, Rugonyi S, Keller C. Preclinical therapeutics ex ovo quail eggs as a biomimetic automation-ready xenograft platform. Scientific Reports. 11: 23302. PMID 34857796 DOI: 10.1038/s41598-021-02509-3  0.193
1998 Keller C, Reynolds A, Lee B, Garcia-Prats J. Congenital Myotonic Dystrophy Requiring Prolonged Endotracheal and Noninvasive Assisted Ventilation: Not a Uniformly Fatal Condition Pediatrics. 101: 704-705. PMID 9521960 DOI: 10.1542/Peds.101.4.704  0.191
2021 Tuohy JL, Byer BJ, Royer S, Keller C, Nagai-Singer MA, Regan DP, Seguin B. Evaluation of Myogenin and MyoD1 as Immunohistochemical Markers of Canine Rhabdomyosarcoma. Veterinary Pathology. 300985820988146. PMID 33691532 DOI: 10.1177/0300985820988146  0.191
1998 Keller C, Shapira SK, Clark GD. A urea cycle defect presenting as acute cerebellar ataxia in a 3-year-old girl. Journal of Child Neurology. 13: 93-5. PMID 9512312 DOI: 10.1177/088307389801300211  0.19
2022 Kim JA, Berlow NE, Lathara M, Bharathy N, Martin LR, Purohit R, Cleary MM, Liu Q, Michalek JE, Srinivasa G, Cole BL, Chen SD, Keller C. Sensitization of osteosarcoma to irradiation by targeting nuclear FGFR1. Biochemical and Biophysical Research Communications. 621: 101-108. PMID 35820279 DOI: 10.1016/j.bbrc.2022.07.002  0.189
2020 Ricker CA, Berlow NE, Crawford KA, Georgopapadakos T, Huelskamp AN, Woods AD, Dhimolea E, Ramkissoon SH, Spunt SL, Rudzinski ER, Keller C. Undifferentiated small round cell sarcoma in a young male: a case report. Cold Spring Harbor Molecular Case Studies. 6. PMID 32014859 DOI: 10.1101/mcs.a004812  0.185
2005 BADI A, KELLER C, NORMANN R, FRIEDLAND D. Three Dimensional Computed Tomography Reconstruction of the Temporal Bone at 21 Micron Resolution Otolaryngology - Head and Neck Surgery. 133: P84-P84. DOI: 10.1016/J.Otohns.2005.05.175  0.185
2023 Kim JA, Crawford KA, Spada PA, Martin LR, Zhang J, Wong R, Reid JM, Stewart CF, Frank TM, Liu Q, Michalek JE, Keller C. Non-chemotherapy adjuvant agents in TP53 mutant Ewing sarcoma. Scientific Reports. 13: 14360. PMID 37658148 DOI: 10.1038/s41598-023-40751-z  0.184
2023 Muench MO, Fomin ME, Gutierrez AG, López-Terrada D, Gilfanova R, Nosworthy C, Beyer AI, Ostolaza G, Kats D, Matlock KL, Cairo S, Keller C. CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastoma. Frontiers in Oncology. 13: 927852. PMID 36845728 DOI: 10.3389/fonc.2023.927852  0.184
2023 Rasmussen SV, Wozniak A, Lathara M, Goldenberg JM, Samudio BM, Bickford LR, Nagamori K, Wright H, Woods AD, Chauhan S, Lee CJ, Rudzinski ER, Swift MK, Kondo T, Fisher DE, ... ... Keller C, et al. Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma. British Journal of Cancer. PMID 36959380 DOI: 10.1038/s41416-023-02222-0  0.159
2016 Dey D, Bagarova J, Hatsell SJ, Armstrong KA, Huang L, Ermann J, Vonner AJ, Shen Y, Mohedas AH, Lee A, Eekhoff EM, van Schie A, Demay MB, Keller C, Wagers AJ, et al. Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification. Science Translational Medicine. 8: 366ra163. PMID 27881824 DOI: 10.1126/Scitranslmed.Aaf1090  0.158
2022 Frankel AO, Lathara M, Shaw CY, Wogmon O, Jackson JM, Clark MM, Eshraghi N, Keenen SE, Woods AD, Purohit R, Ishi Y, Moran N, Eguchi M, Ahmed FUA, Khan S, ... ... Keller C, et al. Machine learning for rhabdomyosarcoma histopathology. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 35449398 DOI: 10.1038/s41379-022-01075-x  0.157
2021 Pacenta HL, Allen-Rhoades W, Langenau D, Houghton PJ, Keller C, Heske CM, Deel MD, Linardic CM, Shern JF, Stewart E, Turpin B, Harrison DJ, Khan J, Mascarenhas L, Skapek SX, et al. Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force. Journal of Clinical Medicine. 10. PMID 33915882 DOI: 10.3390/jcm10071416  0.153
2021 Ricker C, Woods A, Simonson W, Lathara M, Srinivasa G, Rudzinski E, Mansoor A, Irwin R, Keller C, Berlow NE. Refractory Alveolar Rhabdomyosarcoma in a 11-year old male. Cold Spring Harbor Molecular Case Studies. PMID 33436392 DOI: 10.1101/mcs.a005983  0.15
2009 Pauws E, Hoshino A, Bentley L, Prajapati S, Keller C, Hammond P, Martinez-Barbera JP, Moore GE, Stanier P. Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes. Human Molecular Genetics. 18: 4171-9. PMID 19648291 DOI: 10.1093/hmg/ddp368  0.141
2022 Rasmussen SV, Jin JX, Bickford LR, Woods AD, Sahm F, Crawford KA, Nagamori K, Goto H, Torres KE, Sidoni A, Rudzinski ER, Thway K, Jones RL, Ciulli A, Wright H, ... ... Keller C, et al. Functional genomic analysis of epithelioid sarcoma reveals distinct proximal and distal subtype biology. Clinical and Translational Medicine. 12: e961. PMID 35839307 DOI: 10.1002/ctm2.961  0.13
2024 Espinoza AF, Patel RH, Patel KR, Badachhape AA, Whitlock R, Srivastava RK, Govindu SR, Duong A, Kona A, Kureti P, Armbruster B, Kats D, Srinivasan RR, Dobrolecki LE, Yu X, ... ... Keller C, et al. A Novel Treatment Strategy Utilizing Panobinostat for High-Risk and Treatment-Refractory Hepatoblastoma. Journal of Hepatology. PMID 38242326 DOI: 10.1016/j.jhep.2024.01.003  0.13
2014 Prajapati SI, Nevell L, Keller C. Microscopic computed tomography-based skeletal phenotyping for genetic model organisms. Methods in Molecular Biology (Clifton, N.J.). 1092: 221-6. PMID 24318823 DOI: 10.1007/978-1-60327-292-6_14  0.129
2014 Prajapati SI, Rodriguez DR, Keller C. Microscopic computed tomography-based virtual histology of embryos. Methods in Molecular Biology (Clifton, N.J.). 1092: 291-6. PMID 24318828 DOI: 10.1007/978-1-60327-292-6_19  0.105
2012 Topalidou I, Keller C, Kalebic N, Nguyen KC, Somhegyi H, Politi KA, Heppenstall P, Hall DH, Chalfie M. Genetically separable functions of the MEC-17 tubulin acetyltransferase affect microtubule organization. Current Biology : Cb. 22: 1057-65. PMID 22658602 DOI: 10.1016/J.Cub.2012.03.066  0.095
2023 Nicholas BA, Purohit R, Woods AD, Kannan K, Srinivasa G, Bridge JA, Kim JA, Keller C. BCR-ABL is enriched in S- and G-cell cycle phases. Leukemia Research. 126: 107036. PMID 36764024 DOI: 10.1016/j.leukres.2023.107036  0.089
2007 Keller CF. Global warming 2007. An update to global warming: the balance of evidence and its policy implications. Thescientificworldjournal. 7: 381-99. PMID 17370024 DOI: 10.1100/tsw.2007.91  0.08
2004 Zhang S, Arnadottir J, Keller C, Caldwell GA, Yao CA, Chalfie M. MEC-2 is recruited to the putative mechanosensory complex in C. elegans touch receptor neurons through its stomatin-like domain. Current Biology : Cb. 14: 1888-96. PMID 15530389 DOI: 10.1016/J.Cub.2004.10.030  0.072
2021 Lian X, Kats D, Rasmussen S, Martin LR, Karki A, Keller C, Berlow NE. Correction to: Design considerations of an IL13Rα2 antibody-drug conjugate for difuse intrinsic pontine glioma. Acta Neuropathologica Communications. 9: 114. PMID 34172087 DOI: 10.1186/s40478-021-01210-w  0.059
2003 Keller CF. Global warming: the balance of evidence and its policy implications. A review of the current state-of-the-controversy. Thescientificworldjournal. 3: 357-411. PMID 12806101 DOI: 10.1100/tsw.2003.26  0.051
2024 Ho DJ, Agaram NP, Frankel AO, Lathara M, Catchpoole D, Keller C, Hameed MR. Toward Deploying a Deep Learning Model for Diagnosis of Rhabdomyosarcoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 37: 100421. PMID 38335856 DOI: 10.1016/j.modpat.2024.100421  0.034
2014 Herzig R, Nehnevajova E, Pfistner C, Schwitzguebel JP, Ricci A, Keller C. Feasibility of labile Zn phytoextraction using enhanced tobacco and sunflower: results of five- and one-year field-scale experiments in Switzerland. International Journal of Phytoremediation. 16: 735-54. PMID 24933882 DOI: 10.1080/15226514.2013.856846  0.031
2022 Frankel AO, Lathara M, Shaw CY, Wogmon O, Jackson JM, Clark MM, Eshraghi N, Keenen SE, Woods AD, Purohit R, Ishi Y, Moran N, Eguchi M, Ahmed FUA, Khan S, ... ... Keller C, et al. Correction to: Machine learning for rhabdomyosarcoma histopathology. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 35578013 DOI: 10.1038/s41379-022-01098-4  0.01
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