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Mario R. Capecchi - Publications

Human Genetics University of Utah, Salt Lake City, UT 

238 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Panza E, Ozenberger BB, Straessler KM, Barrott JJ, Li L, Wang Y, Xie M, Boulet A, Titen SWA, Mason CC, Lazar AJ, Ding L, Capecchi MR, Jones KB. The clear cell sarcoma functional genomic landscape. The Journal of Clinical Investigation. PMID 34156976 DOI: 10.1172/JCI146301  0.4
2019 Tränkner D, Boulet A, Peden E, Focht R, Van Deren D, Capecchi M. A Microglia Sublineage Protects from Sex-Linked Anxiety Symptoms and Obsessive Compulsion. Cell Reports. 29: 791-799.e3. PMID 31644903 DOI: 10.1016/j.celrep.2019.09.045  0.4
2019 Patel N, Wang J, Shiozawa K, Jones KB, Zhang Y, Prokop JW, Davenport GG, Nihira NT, Hao Z, Wong D, Brandsmeier L, Meadows SK, Sampaio AV, Werff RV, Endo M, ... Capecchi MR, et al. HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression. Iscience. 13: 43-54. PMID 30818224 DOI: 10.1016/J.Isci.2019.02.008  0.4
2019 De S, Van Deren D, Peden E, Hockin M, Boulet A, Titen S, Capecchi MR. Correction: Two distinct ontogenies confer heterogeneity to mouse brain microglia (doi: 10.1242/dev.152306). Development (Cambridge, England). 146. PMID 30733225 DOI: 10.1242/dev.175901  0.4
2018 Yu D, Wang J, Zou H, Feng T, Chen L, Li J, Qi X, Li Z, Duan X, Xu C, Zhang L, Long X, Lan J, Chen C, Wang C, ... ... Capecchi MR, et al. Silencing of retrotransposon-derived imprinted gene RTL1 is the main cause for postimplantational failures in mammalian cloning. Proceedings of the National Academy of Sciences of the United States of America. PMID 30381455 DOI: 10.1073/pnas.1814514115  0.44
2018 Banito A, Li X, Laporte AN, Roe JS, Sanchez-Vega F, Huang CH, Dancsok AR, Hatzi K, Chen CC, Tschaharganeh DF, Chandwani R, Tasdemir N, Jones KB, Capecchi MR, Vakoc CR, et al. The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma. Cancer Cell. 34: 346-348. PMID 30107180 DOI: 10.1016/J.Ccell.2018.07.006  0.4
2018 De S, Van Deren D, Peden E, Hockin M, Boulet A, Titen S, Capecchi MR. Two distinct ontogenies confer heterogeneity to mouse brain microglia. Development (Cambridge, England). 145. PMID 29973370 DOI: 10.1242/dev.152306  0.4
2018 Banito A, Li X, Laporte AN, Roe JS, Sanchez-Vega F, Huang CH, Dancsok AR, Hatzi K, Chen CC, Tschaharganeh DF, Chandwani R, Tasdemir N, Jones KB, Capecchi MR, Vakoc CR, et al. The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma. Cancer Cell. PMID 29502955 DOI: 10.1016/J.Ccell.2018.01.018  0.4
2017 Barrott JJ, Illum BE, Jin H, Hedberg ML, Wang Y, Grossmann A, Haldar M, Capecchi MR, Jones KB. Paracrine osteoprotegerin and β-catenin stabilization support synovial sarcomagenesis in periosteal cells. The Journal of Clinical Investigation. PMID 29202462 DOI: 10.1172/Jci94955  0.68
2017 Nagarajan N, Jones BW, West PJ, Marc RE, Capecchi MR. Corticostriatal circuit defects in Hoxb8 mutant mice. Molecular Psychiatry. PMID 29180671 DOI: 10.1038/mp.2017.251  0.36
2017 Nagarajan N, Jones BW, West PJ, Marc RE, Capecchi MR. Corticostriatal circuit defects in Hoxb8 mutant mice. Molecular Psychiatry. PMID 28948967 DOI: 10.1038/mp.2017.180  0.36
2017 Barrott JJ, Zhu JF, Smith-Fry K, Susko AM, Nollner D, Burrell L, Pozner A, Capecchi MR, Yap JT, Cannon-Albright LA, Deng X, Jones KB. The influential role of BCL2 family members in synovial sarcomagenesis. Molecular Cancer Research : McR. PMID 28851813 DOI: 10.1158/1541-7786.MCR-17-0315  0.52
2017 Ruff JS, Saffarini RB, Ramoz LL, Morrison LC, Baker S, Laverty SM, Tvrdik P, Capecchi MR, Potts WK. Mouse fitness measures reveal incomplete functional redundancy of Hox paralogous group 1 proteins. Plos One. 12: e0174975. PMID 28380068 DOI: 10.1371/Journal.Pone.0174975  1
2017 Kim G, Nagarajan N, Pastuzyn E, Jenks K, Capecchi M, Shepherd J, Menon R. Deep-brain imaging via epi-fluorescence Computational Cannula Microscopy. Scientific Reports. 7: 44791. PMID 28317915 DOI: 10.1038/Srep44791  0.36
2017 Li S, Lan H, Men H, Wu Y, Li N, Capecchi MR, Bryda EC, Wu S. Derivation of Transgene-Free Rat Induced Pluripotent Stem Cells Approximating the Quality of Embryonic Stem Cells. Stem Cells Translational Medicine. 6: 340-351. PMID 28191784 DOI: 10.5966/Sctm.2015-0390  0.44
2017 Xu C, Qi X, Du X, Zou H, Gao F, Feng T, Lu H, Li S, An X, Zhang L, Wu Y, Liu Y, Li N, Capecchi MR, Wu S. piggyBac mediates efficient in vivo CRISPR library screening for tumorigenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28062688 DOI: 10.1073/pnas.1615735114  0.44
2017 Kim G, Nagarajan N, Pastuzyn E, Jenks K, Capecchi M, Shepherd J, Menon R. Computational Cannula Microscopy: Fluorescent imaging through ultra-thin glass needle Rundbrief Der Gi-Fachgruppe 5.10 Informationssystem-Architekturen. DOI: 10.1364/Isa.2017.Ith1E.2  0.36
2017 Kim G, Nagarajan N, Pastuzyn E, Jenks K, Capecchi M, Shepherd J, Menon R. Deep tissue fluorescent imaging via computational cannula microscopy Brain. DOI: 10.1364/Brain.2017.Brm4B.7  0.44
2016 Barrott JJ, Kafchinski LA, Jin H, Potter JW, Kannan SD, Kennedy R, Mosbruger T, Wang WL, Tsai JW, Araujo DM, Liu T, Capecchi MR, Lazar AJ, Jones KB. Modeling synovial sarcoma metastasis in the mouse: PI3'-lipid signaling and inflammation. The Journal of Experimental Medicine. 213: 2989-3005. PMID 27956588 DOI: 10.1084/jem.20160817  0.4
2016 Wu S, Mariotti M, Santesmasses D, Hill KE, Baclaocos J, Aparicio-Prat E, Li S, Mackrill J, Wu Y, Howard MT, Capecchi M, Guigó R, Burk RF, Atkins JF. Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements. Open Biology. 6. PMID 27881738 DOI: 10.1098/rsob.160241  0.44
2016 Zhang X, Wei X, Wu Y, Wang Y, Tan C, Hu X, Li N, Capecchi MR, Wu S. Genome-wide piggyBac transposon mediated screening reveals genes related to reprogramming. Protein & Cell. PMID 27761808 DOI: 10.1007/s13238-016-0332-z  1
2016 Li S, Lan H, Men H, Wu Y, Li N, Capecchi MR, Bryda EC, Wu S. Derivation of Transgene-Free Rat Induced Pluripotent Stem Cells Approximating the Quality of Embryonic Stem Cells. Stem Cells Translational Medicine. PMID 27625042 DOI: 10.5966/sctm.2015-0390  0.44
2016 Lan H, Li S, Guo Z, Men H, Wu Y, Li N, Bryda EC, Capecchi MR, Wu S. Efficient Generation of Selection-Gene-Free Rat Knockout Models by Homologous Recombination in ES Cells. Febs Letters. PMID 27597178 DOI: 10.1002/1873-3468.12388  0.44
2016 Jones KB, Barrott JJ, Xie M, Haldar M, Jin H, Zhu JF, Monument MJ, Mosbruger TL, Langer EM, Randall RL, Wilson RK, Cairns BR, Ding L, Capecchi MR. The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis. Oncogene. PMID 26947017 DOI: 10.1038/onc.2016.38  1
2016 Jones KB, Barrott JJ, Jin H, Haldar M, Capecchi MR. Abstract 03: The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis Clinical Cancer Research. 22: 3-3. DOI: 10.1158/1557-3265.Pmsclingen15-03  0.68
2015 Capecchi MR, Pozner A. ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination. Nature Communications. 6: 8763. PMID 26581405 DOI: 10.1038/ncomms9763  1
2015 Prigge JR, Hoyt TR, Dobrinen E, Capecchi MR, Schmidt EE, Meissner N. Type I IFNs Act upon Hematopoietic Progenitors To Protect and Maintain Hematopoiesis during Pneumocystis Lung Infection in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 26519535 DOI: 10.4049/Jimmunol.1501553  1
2015 Carroll LS, Capecchi MR. HOXC8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression, and Wnt/β-catenin signaling. Development (Cambridge, England). PMID 26459221 DOI: 10.1242/Dev.128298  1
2015 Roux M, Laforest B, Capecchi M, Bertrand N, Zaffran S. Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development. Developmental Biology. 406: 247-58. PMID 26284287 DOI: 10.1016/J.Ydbio.2015.08.015  1
2015 Barrott JJ, Illum BE, Jin H, Zhu JF, Mosbruger T, Monument MJ, Smith-Fry K, Cable MG, Wang Y, Grossmann AH, Capecchi MR, Jones KB. β-catenin stabilization enhances SS18-SSX2-driven synovial sarcomagenesis and blocks the mesenchymal to epithelial transition. Oncotarget. PMID 26259251 DOI: 10.18632/Oncotarget.4283  1
2015 Pozner A, Xu B, Palumbos S, Gee JM, Tvrdik P, Capecchi MR. Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse. Frontiers in Molecular Neuroscience. 8: 12. PMID 26005403 DOI: 10.3389/Fnmol.2015.00012  1
2015 Gee JM, Gibbons MB, Taheri M, Palumbos S, Morris SC, Smeal RM, Flynn KF, Economo MN, Cizek CG, Capecchi MR, Tvrdik P, Wilcox KS, White JA. Imaging activity in astrocytes and neurons with genetically encoded calcium indicators following in utero electroporation. Frontiers in Molecular Neuroscience. 8: 10. PMID 25926768 DOI: 10.3389/Fnmol.2015.00010  1
2015 Kim G, Nagarajan N, Meiri A, Merrill S, Capecchi M, Jorgensen EM, Menon R. A cannula-based computational fluorescence microscope Rundbrief Der Gi-Fachgruppe 5.10 Informationssystem-Architekturen. DOI: 10.1364/Isa.2015.It2A.3  0.36
2015 Kim G, Nagarajan N, Meiri A, Merrill S, Capecchi M, Jorgensen EM, Menon R. A cannula-based computational fluorescence microscope for neuronal imaging Conference On Lasers and Electro-Optics Europe - Technical Digest. 2015. DOI: 10.1364/CLEO_SI.2015.STu2K.7  1
2015 Kim G, Nagarajan N, Capecchi MR, Menon R. Cannula-based computational fluorescence microscopy Applied Physics Letters. 106. DOI: 10.1063/1.4923402  1
2014 Haldar M, Karan G, Watanabe S, Guenther S, Braun T, Capecchi MR. Response: Contributions of the Myf5-independent lineage to myogenesis. Developmental Cell. 31: 539-41. PMID 25490265 DOI: 10.1016/J.Devcel.2014.11.010  1
2014 Goodwin ML, Jin H, Straessler K, Smith-Fry K, Zhu JF, Monument MJ, Grossmann A, Randall RL, Capecchi MR, Jones KB. Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironment. Cancer Cell. 26: 851-62. PMID 25453902 DOI: 10.1016/j.ccell.2014.10.003  1
2014 Quist T, Jin H, Zhu JF, Smith-Fry K, Capecchi MR, Jones KB. The impact of osteoblastic differentiation on osteosarcomagenesis in the mouse. Oncogene. PMID 25347737 DOI: 10.1038/onc.2014.354  1
2014 Savai R, Al-Tamari HM, Sedding D, Kojonazarov B, Muecke C, Teske R, Capecchi MR, Weissmann N, Grimminger F, Seeger W, Schermuly RT, Pullamsetti SS. Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension. Nature Medicine. 20: 1289-300. PMID 25344740 DOI: 10.1038/nm.3695  1
2014 Chojnowski JL, Masuda K, Trau HA, Thomas K, Capecchi M, Manley NR. Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse. Development (Cambridge, England). 141: 3697-708. PMID 25249461 DOI: 10.1242/Dev.110833  1
2014 Gee JM, Smith NA, Fernandez FR, Economo MN, Brunert D, Rothermel M, Morris SC, Talbot A, Palumbos S, Ichida JM, Shepherd JD, West PJ, Wachowiak M, Capecchi MR, Wilcox KS, et al. Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse. Neuron. 83: 1058-72. PMID 25155958 DOI: 10.1016/J.Neuron.2014.07.024  1
2014 Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, ... ... Capecchi MR, et al. Lineage of origin in rhabdomyosarcoma informs pharmacological response. Genes & Development. 28: 1578-91. PMID 25030697 DOI: 10.1101/Gad.238733.114  1
2014 Wu S, Wu Y, Zhang X, Capecchi MR. Efficient germ-line transmission obtained with transgene-free induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 10678-83. PMID 25002522 DOI: 10.1073/pnas.1409933111  1
2014 Sui D, Sun Z, Xu C, Wu Y, Capecchi MR, Wu S, Li N. Fine-tuning of iPSC derivation by an inducible reprogramming system at the protein level. Stem Cell Reports. 2: 721-33. PMID 24936457 DOI: 10.1016/j.stemcr.2014.03.013  1
2014 Kurokawa S, Eriksson S, Rose KL, Wu S, Motley AK, Hill S, Winfrey VP, McDonald WH, Capecchi MR, Atkins JF, Arnér ES, Hill KE, Burk RF. Sepp1(UF) forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1. Free Radical Biology & Medicine. 69: 67-76. PMID 24434121 DOI: 10.1016/j.freeradbiomed.2014.01.010  1
2014 Hockin M, Sant HJ, Capecchi M, Gale BK. An inertial microfluidic device for rapid purification of native chromosomes 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 2510-2511.  1
2013 Prigge JR, Wiley JA, Talago EA, Young EM, Johns LL, Kundert JA, Sonsteng KM, Halford WP, Capecchi MR, Schmidt EE. Nuclear double-fluorescent reporter for in vivo and ex vivo analyses of biological transitions in mouse nuclei. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 24022199 DOI: 10.1007/S00335-013-9469-8  1
2013 Barham W, Frump AL, Sherrill TP, Garcia CB, Saito-Diaz K, VanSaun MN, Fingleton B, Gleaves L, Orton D, Capecchi MR, Blackwell TS, Lee E, Yull F, Eid JE. Targeting the Wnt pathway in synovial sarcoma models. Cancer Discovery. 3: 1286-301. PMID 23921231 DOI: 10.1158/2159-8290.Cd-13-0138  1
2013 Iverson SV, Eriksson S, Xu J, Prigge JR, Talago EA, Meade TA, Meade ES, Capecchi MR, Arnér ES, Schmidt EE. A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification. Free Radical Biology & Medicine. 63: 369-80. PMID 23743293 DOI: 10.1016/J.Freeradbiomed.2013.05.028  1
2013 Biehs B, Hu JK, Strauli NB, Sangiorgi E, Jung H, Heber RP, Ho S, Goodwin AF, Dasen JS, Capecchi MR, Klein OD. BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. Nature Cell Biology. 15: 846-52. PMID 23728424 DOI: 10.1038/Ncb2766  1
2013 Gahring LC, Enioutina EY, Myers EJ, Spangrude GJ, Efimova OV, Kelley TW, Tvrdik P, Capecchi MR, Rogers SW. Nicotinic receptor alpha7 expression identifies a novel hematopoietic progenitor lineage. Plos One. 8: e57481. PMID 23469197 DOI: 10.1371/Journal.Pone.0057481  1
2013 Straessler KM, Jones KB, Hu H, Jin H, van de Rijn M, Capecchi MR. Modeling clear cell sarcomagenesis in the mouse: cell of origin differentiation state impacts tumor characteristics. Cancer Cell. 23: 215-27. PMID 23410975 DOI: 10.1016/j.ccr.2012.12.019  1
2013 Jones KB, Datar M, Ravichandran S, Jin H, Jurrus E, Whitaker R, Capecchi MR. Toward an understanding of the short bone phenotype associated with multiple osteochondromas. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 651-7. PMID 23192691 DOI: 10.1002/Jor.22280  1
2013 Jones KB, Su L, Jin H, Lenz C, Randall RL, Underhill TM, Nielsen TO, Sharma S, Capecchi MR. SS18-SSX2 and the mitochondrial apoptosis pathway in mouse and human synovial sarcomas. Oncogene. 32: 2365-71, 2375.e1-5. PMID 22797074 DOI: 10.1038/onc.2012.247  1
2013 Jones KB, Illum B, Jin H, Mu JZ, Monument M, Grossmann A, Capecchi MR. Abstract C12: Beta-catenin enhances synovial sarcomagenesis and provides a therapeutic target. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C12  0.4
2012 Hill KE, Wu S, Motley AK, Stevenson TD, Winfrey VP, Capecchi MR, Atkins JF, Burk RF. Production of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasis. The Journal of Biological Chemistry. 287: 40414-24. PMID 23038251 DOI: 10.1074/jbc.M112.421404  1
2012 Boulet AM, Capecchi MR. Signaling by FGF4 and FGF8 is required for axial elongation of the mouse embryo. Developmental Biology. 371: 235-45. PMID 22954964 DOI: 10.1016/j.ydbio.2012.08.017  1
2012 Suo L, Lu H, Ying G, Capecchi MR, Wu Q. Protocadherin clusters and cell adhesion kinase regulate dendrite complexity through Rho GTPase. Journal of Molecular Cell Biology. 4: 362-76. PMID 22730554 DOI: 10.1093/Jmcb/Mjs034  1
2012 Rogers SW, Tvrdik P, Capecchi MR, Gahring LC. Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure. American Journal of Medical Genetics. Part A. 158: 1135-44. PMID 22473653 DOI: 10.1002/Ajmg.A.35372  1
2012 Su L, Sampaio AV, Jones KB, Pacheco M, Goytain A, Lin S, Poulin N, Yi L, Rossi FM, Kast J, Capecchi MR, Underhill TM, Nielsen TO. Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics. Cancer Cell. 21: 333-47. PMID 22439931 DOI: 10.1016/J.Ccr.2012.01.010  1
2012 Prigge JR, Eriksson S, Iverson SV, Meade TA, Capecchi MR, Arnér ES, Schmidt EE. Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1. Free Radical Biology & Medicine. 52: 803-10. PMID 22198266 DOI: 10.1016/J.Freeradbiomed.2011.11.025  1
2012 Yan KS, Chia LA, Li X, Ootani A, Su J, Lee JY, Su N, Luo Y, Heilshorn SC, Amieva MR, Sangiorgi E, Capecchi MR, Kuo CJ. The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. Proceedings of the National Academy of Sciences of the United States of America. 109: 466-71. PMID 22190486 DOI: 10.1073/Pnas.1118857109  1
2012 Makki N, Capecchi MR. Cardiovascular defects in a mouse model of HOXA1 syndrome. Human Molecular Genetics. 21: 26-31. PMID 21940751 DOI: 10.1093/Hmg/Ddr434  1
2012 Tvrdik P, Capecchi MR. Gene Targeting The Mouse Nervous System. 19-35. DOI: 10.1016/B978-0-12-369497-3.10002-0  1
2011 Makki N, Capecchi MR. Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development. Developmental Biology. 357: 295-304. PMID 21784065 DOI: 10.1016/J.Ydbio.2011.06.042  1
2011 Jones KB, Haldar M, Schiffman JD, Cannon-Albright L, Lessnick SL, Sharma S, Capecchi MR, Randall RL. Of mice and men: opportunities to use genetically engineered mouse models of synovial sarcoma for preclinical cancer therapeutic evaluation. Cancer Control : Journal of the Moffitt Cancer Center. 18: 196-203. PMID 21666582 DOI: 10.1177/107327481101800307  1
2011 Bertrand N, Roux M, Ryckebüsch L, Niederreither K, Dollé P, Moon A, Capecchi M, Zaffran S. Hox genes define distinct progenitor sub-domains within the second heart field. Developmental Biology. 353: 266-74. PMID 21385575 DOI: 10.1016/J.Ydbio.2011.02.029  1
2011 Angus-Hill ML, Elbert KM, Hidalgo J, Capecchi MR. T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 4914-9. PMID 21383188 DOI: 10.1073/Pnas.1102300108  1
2011 Rubin BP, Nishijo K, Chen HI, Yi X, Schuetze DP, Pal R, Prajapati SI, Abraham J, Arenkiel BR, Chen QR, Davis S, McCleish AT, Capecchi MR, Michalek JE, Zarzabal LA, et al. Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma. Cancer Cell. 19: 177-91. PMID 21316601 DOI: 10.1016/J.Ccr.2010.12.023  1
2011 Guo T, Mandai K, Condie BG, Wickramasinghe SR, Capecchi MR, Ginty DD. An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. Nature Neuroscience. 14: 31-6. PMID 21151121 DOI: 10.1038/Nn.2710  1
2011 Zadravec D, Tvrdik P, Guillou H, Haslam R, Kobayashi T, Napier JA, Capecchi MR, Jacobsson A. ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice. Journal of Lipid Research. 52: 245-55. PMID 21106902 DOI: 10.1194/Jlr.M011346  1
2010 Rollins MF, van der Heide DM, Weisend CM, Kundert JA, Comstock KM, Suvorova ES, Capecchi MR, Merrill GF, Schmidt EE. Hepatocytes lacking thioredoxin reductase 1 have normal replicative potential during development and regeneration. Journal of Cell Science. 123: 2402-12. PMID 20571049 DOI: 10.1242/Dev.055947  1
2010 Chen SK, Tvrdik P, Peden E, Cho S, Wu S, Spangrude G, Capecchi MR. Hematopoietic origin of pathological grooming in Hoxb8 mutant mice. Cell. 141: 775-85. PMID 20510925 DOI: 10.1016/J.Cell.2010.03.055  1
2010 Makki N, Capecchi MR. Hoxa1 lineage tracing indicates a direct role for Hoxa1 in the development of the inner ear, the heart, and the third rhombomere. Developmental Biology. 341: 499-509. PMID 20171203 DOI: 10.1016/J.Ydbio.2010.02.014  1
2010 Tripathi P, Guo Q, Wang Y, Coussens M, Liapis H, Jain S, Kuehn MR, Capecchi MR, Chen F. Midline signaling regulates kidney positioning but not nephrogenesis through Shh. Developmental Biology. 340: 518-27. PMID 20152829 DOI: 10.1016/j.ydbio.2010.02.007  1
2010 Jones KB, Piombo V, Searby C, Kurriger G, Yang B, Grabellus F, Roughley PJ, Morcuende JA, Buckwalter JA, Capecchi MR, Vortkamp A, Sheffield VC. A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes. Proceedings of the National Academy of Sciences of the United States of America. 107: 2054-9. PMID 20080592 DOI: 10.1073/Pnas.0910875107  1
2010 Haldar M, Hedberg ML, Jones KB, Capecchi MR. Abstract 4195: Tetracycline inducible expression of synovial sarcoma associated SYT-SSX2 fusion gene in a new mouse model Cancer Research. 70: 4195-4195. DOI: 10.1158/1538-7445.Am10-4195  0.68
2009 Suvorova ES, Lucas O, Weisend CM, Rollins MF, Merrill GF, Capecchi MR, Schmidt EE. Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes. Plos One. 4: e6158. PMID 19584930 DOI: 10.1371/Journal.Pone.0006158  1
2009 Xue H, Wu S, Papadeas ST, Spusta S, Swistowska AM, MacArthur CC, Mattson MP, Maragakis NJ, Capecchi MR, Rao MS, Zeng X, Liu Y. A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells. Stem Cells (Dayton, Ohio). 27: 1836-46. PMID 19544414 DOI: 10.1002/Stem.129  1
2009 Ootani A, Li X, Sangiorgi E, Ho QT, Ueno H, Toda S, Sugihara H, Fujimoto K, Weissman IL, Capecchi MR, Kuo CJ. Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche. Nature Medicine. 15: 701-6. PMID 19398967 DOI: 10.1038/nm.1951  1
2009 Sangiorgi E, Capecchi MR. Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 106: 7101-6. PMID 19372370 DOI: 10.1073/pnas.0902508106  1
2009 Haldar M, Hedberg ML, Hockin MF, Capecchi MR. A CreER-based random induction strategy for modeling translocation-associated sarcomas in mice. Cancer Research. 69: 3657-64. PMID 19351831 DOI: 10.1158/0008-5472.Can-08-4127  1
2009 Nishijo K, Hosoyama T, Bjornson CR, Schaffer BS, Prajapati SI, Bahadur AN, Hansen MS, Blandford MC, McCleish AT, Rubin BP, Epstein JA, Rando TA, Capecchi MR, Keller C. Biomarker system for studying muscle, stem cells, and cancer in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2681-90. PMID 19332644 DOI: 10.1096/Fj.08-128116  1
2009 Ying G, Wu S, Hou R, Huang W, Capecchi MR, Wu Q. The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain. Molecular and Cellular Biology. 29: 3045-61. PMID 19332558 DOI: 10.1128/Mcb.00011-09  1
2009 Taniguchi E, Cho MJ, Arenkiel BR, Hansen MS, Rivera OJ, McCleish AT, Qualman SJ, Guttridge DC, Scott MP, Capecchi MR, Keller C. Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma. Pediatric Blood & Cancer. 53: 136-44. PMID 19213072 DOI: 10.1002/Pbc.21968  1
2009 Capecchi MR. The role of Hox genes in hindbrain development Molecular and Cellular Approaches to Neural Development. DOI: 10.1093/acprof:oso/9780195111668.003.0009  1
2008 Capecchi M. The first transgenic mice: An interview with Mario Capecchi Dmm Disease Models and Mechanisms. 1: 197-201. PMID 19093023 DOI: 10.1242/dmm.001966  1
2008 Ray R, Capecchi M. An examination of the Chiropteran HoxD locus from an evolutionary perspective Evolution and Development. 10: 657-670. PMID 19021736 DOI: 10.1111/J.1525-142X.2008.00279.X  1
2008 Jia Q, McDill BW, Sankarapandian B, Wu S, Liapis H, Holzman LB, Capecchi MR, Miner JH, Chen F. Ablation of developing podocytes disrupts cellular interactions and nephrogenesis both inside and outside the glomerulus. American Journal of Physiology. Renal Physiology. 295: F1790-8. PMID 18842818 DOI: 10.1152/Ajprenal.90519.2008  1
2008 Sangiorgi E, Shuhua Z, Capecchi MR. In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette. Nucleic Acids Research. 36: e134. PMID 18829714 DOI: 10.1093/nar/gkn627  1
2008 Kundert JA, Sealey AL, Li Y, Capecchi MR, Schmidt EE. Syngeneic immune-dependent abortions in mice suggest paternal alloantigen-independent mechanisms. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 60: 290-7. PMID 18759828 DOI: 10.1111/J.1600-0897.2008.00622.X  1
2008 Haldar M, Randall RL, Capecchi MR. Synovial sarcoma: from genetics to genetic-based animal modeling. Clinical Orthopaedics and Related Research. 466: 2156-67. PMID 18563504 DOI: 10.1007/S11999-008-0340-2  1
2008 Capecchi MR. The making of a scientist II (Nobel Lecture). Chembiochem : a European Journal of Chemical Biology. 9: 1530-43. PMID 18551693 DOI: 10.1002/cbic.200800239  1
2008 Wu S, Ying G, Wu Q, Capecchi MR. A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond. Nature Protocols. 3: 1056-76. PMID 18546598 DOI: 10.1038/Nprot.2008.70  1
2008 Sangiorgi E, Capecchi MR. Bmi1 is expressed in vivo in intestinal stem cells. Nature Genetics. 40: 915-20. PMID 18536716 DOI: 10.1038/ng.165  1
2008 Haldar M, Karan G, Tvrdik P, Capecchi MR. Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis. Developmental Cell. 14: 437-45. PMID 18331721 DOI: 10.1016/J.Devcel.2008.01.002  1
2008 Vasquez SX, Hansen MS, Bahadur AN, Hockin MF, Kindlmann GL, Nevell L, Wu IQ, Grunwald DJ, Weinstein DM, Jones GM, Johnson CR, Vandeberg JL, Capecchi MR, Keller C. Optimization of volumetric computed tomography for skeletal analysis of model genetic organisms. Anatomical Record (Hoboken, N.J. : 2007). 291: 475-87. PMID 18286615 DOI: 10.1002/Ar.20670  1
2008 Capecchi MR. A Nobel lesson: the grant behind the prize. Response. Science (New York, N.Y.). 319: 900-1. PMID 18283726  1
2008 Fuchs S, Xiao HD, Hubert C, Michaud A, Campbell DJ, Adams JW, Capecchi MR, Corvol P, Bernstein KE. Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo. Hypertension. 51: 267-74. PMID 18158355 DOI: 10.1161/Hypertensionaha.107.097865  1
2008 Wu Y, Wang G, Scott SA, Capecchi MR. Hoxc10 and Hoxd10 regulate mouse columnar, divisional and motor pool identity of lumbar motoneurons. Development (Cambridge, England). 135: 171-82. PMID 18065432 DOI: 10.1242/dev.009225  1
2007 Barrow JR, Howell WD, Rule M, Hayashi S, Thomas KR, Capecchi MR, McMahon AP. Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Developmental Biology. 312: 312-20. PMID 18028899 DOI: 10.1016/J.Ydbio.2007.09.030  1
2007 Bondareva AA, Capecchi MR, Iverson SV, Li Y, Lopez NI, Lucas O, Merrill GF, Prigge JR, Siders AM, Wakamiya M, Wallin SL, Schmidt EE. Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radical Biology & Medicine. 43: 911-23. PMID 17697936 DOI: 10.1016/J.Freeradbiomed.2007.05.026  1
2007 McIntyre DC, Rakshit S, Yallowitz AR, Loken L, Jeannotte L, Capecchi MR, Wellik DM. Hox patterning of the vertebrate rib cage. Development (Cambridge, England). 134: 2981-9. PMID 17626057 DOI: 10.1242/Dev.007567  1
2007 Wu S, Ying G, Wu Q, Capecchi MR. Toward simpler and faster genome-wide mutagenesis in mice. Nature Genetics. 39: 922-30. PMID 17572674 DOI: 10.1038/Ng2060  1
2007 Shen XZ, Li P, Weiss D, Fuchs S, Xiao HD, Adams JA, Williams IR, Capecchi MR, Taylor WR, Bernstein KE. Mice with enhanced macrophage angiotensin-converting enzyme are resistant to melanoma. The American Journal of Pathology. 170: 2122-34. PMID 17525278 DOI: 10.2353/Ajpath.2007.061205  1
2007 Haldar M, Hancock JD, Coffin CM, Lessnick SL, Capecchi MR. A conditional mouse model of synovial sarcoma: insights into a myogenic origin. Cancer Cell. 11: 375-88. PMID 17418413 DOI: 10.1016/J.Ccr.2007.01.016  1
2007 Capecchi MR, Makki N. WITHDRAWN: Analysing the role of Hoxa1 in mammalian hindbrain, inner ear and cardiovascular development Developmental Biology. 306: 406. DOI: 10.1016/J.Ydbio.2007.03.435  1
2006 Tvrdik P, Capecchi MR. Reversal of Hox1 gene subfunctionalization in the mouse. Developmental Cell. 11: 239-50. PMID 16890163 DOI: 10.1016/j.devcel.2006.06.016  1
2006 Frenzel K, Wallace TA, McDoom I, Xiao HD, Capecchi MR, Bernstein KE, Sayeski PP. A functional Jak2 tyrosine kinase domain is essential for mouse development. Experimental Cell Research. 312: 2735-44. PMID 16887119 DOI: 10.1016/J.Yexcr.2006.05.004  1
2006 Vorbach C, Capecchi MR, Penninger JM. Evolution of the mammary gland from the innate immune system? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 28: 606-16. PMID 16700061 DOI: 10.1002/Bies.20423  1
2006 Johnson JT, Hansen MS, Wu I, Healy LJ, Johnson CR, Jones GM, Capecchi MR, Keller C. Virtual histology of transgenic mouse embryos for high-throughput phenotyping. Plos Genetics. 2: e61. PMID 16683035 DOI: 10.1371/Journal.Pgen.0020061  1
2006 Wu S, Wu Y, Capecchi MR. Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Development (Cambridge, England). 133: 581-90. PMID 16407399 DOI: 10.1242/dev.02236  1
2006 Westerberg R, Månsson JE, Golozoubova V, Shabalina IG, Backlund EC, Tvrdik P, Retterstøl K, Capecchi MR, Jacobsson A. ELOVL3 is an important component for early onset of lipid recruitment in brown adipose tissue. The Journal of Biological Chemistry. 281: 4958-68. PMID 16326704 DOI: 10.1074/Jbc.M511588200  1
2005 Kindlmann GL, Weinstein DM, Jones GM, Johnson CR, Capecchi MR, Keller C. Practical vessel imaging by computed tomography in live transgenic mouse models for human tumors. Molecular Imaging. 4: 417-24. PMID 16285903 DOI: 10.2310/7290.2005.05166  1
2005 Fuchs S, Frenzel K, Hubert C, Lyng R, Muller L, Michaud A, Xiao HD, Adams JW, Capecchi MR, Corvol P, Shur BD, Bernstein KE. Male fertility is dependent on dipeptidase activity of testis ACE. Nature Medicine. 11: 1140-2; author reply. PMID 16270063 DOI: 10.1038/Nm1105-1140  1
2005 Keller C, Capecchi MR. New genetic tactics to model alveolar rhabdomyosarcoma in the mouse. Cancer Research. 65: 7530-2. PMID 16140913 DOI: 10.1158/0008-5472.Can-05-0477  1
2005 Capecchi M. An interview with...Mario Capecchi. Interview by Magdalena Skipper Nature Reviews. Genetics. 6: 434. PMID 15934189 DOI: 10.1038/Nrg1647  1
2005 Capecchi MR. Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century. Nature Reviews. Genetics. 6: 507-12. PMID 15931173 DOI: 10.1038/nrg1619  1
2005 Schindehütte J, Fukumitsu H, Collombat P, Griesel G, Brink C, Baier PC, Capecchi MR, Mansouri A. In vivo and in vitro tissue-specific expression of green fluorescent protein using the cre-lox system in mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 10-5. PMID 15625119 DOI: 10.1634/stemcells.2004-0163  1
2004 Keller C, Hansen MS, Coffin CM, Capecchi MR. Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. Genes & Development. 18: 2608-13. PMID 15520281 DOI: 10.1101/Gad.1243904  1
2004 Keller C, Arenkiel BR, Coffin CM, El-Bardeesy N, DePinho RA, Capecchi MR. Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. Genes & Development. 18: 2614-26. PMID 15489287 DOI: 10.1101/Gad.1244004  1
2004 Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/Ng0904-921  1
2004 Xiao HD, Fuchs S, Campbell DJ, Lewis W, Dudley SC, Kasi VS, Hoit BD, Keshelava G, Zhao H, Capecchi MR, Bernstein KE. Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. The American Journal of Pathology. 165: 1019-32. PMID 15331425 DOI: 10.1016/S0002-9440(10)63363-9  1
2004 Boulet AM, Moon AM, Arenkiel BR, Capecchi MR. The roles of Fgf4 and Fgf8 in limb bud initiation and outgrowth. Developmental Biology. 273: 361-72. PMID 15328019 DOI: 10.1016/J.Ydbio.2004.06.012  1
2004 Arenkiel BR, Tvrdik P, Gaufo GO, Capecchi MR. Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitry. Genes & Development. 18: 1539-52. PMID 15198977 DOI: 10.1101/Gad.1207204  1
2004 Gaufo GO, Wu S, Capecchi MR. Contribution of Hox genes to the diversity of the hindbrain sensory system. Development (Cambridge, England). 131: 1259-66. PMID 14960494 DOI: 10.1242/Dev.01029  1
2004 Fuchs S, Xiao HD, Cole JM, Adams JW, Frenzel K, Michaud A, Zhao H, Keshelava G, Capecchi MR, Corvol P, Bernstein KE. Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice. The Journal of Biological Chemistry. 279: 15946-53. PMID 14757757 DOI: 10.1074/Jbc.M400149200  1
2004 Boulet AM, Capecchi MR. Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod. Development (Cambridge, England). 131: 299-309. PMID 14668414 DOI: 10.1242/dev.00936  1
2004 Westerberg R, Tvrdik P, Undén AB, Månsson JE, Norlén L, Jakobsson A, Holleran WH, Elias PM, Asadi A, Flodby P, Toftgård R, Capecchi MR, Jacobsson A. Role for ELOVL3 and fatty acid chain length in development of hair and skin function. The Journal of Biological Chemistry. 279: 5621-9. PMID 14581464 DOI: 10.1074/jbc.M310529200  1
2004 Wong KH, Wintch HD, Capecchi MR. Hoxa11 regulates stromal cell death and proliferation during neonatal uterine development. Molecular Endocrinology (Baltimore, Md.). 18: 184-93. PMID 14551265 DOI: 10.1210/me.2003-0222  1
2003 Vorbach C, Harrison R, Capecchi MR. Xanthine oxidoreductase is central to the evolution and function of the innate immune system. Trends in Immunology. 24: 512-7. PMID 12967676 DOI: 10.1016/S1471-4906(03)00237-0  1
2003 Gaufo GO, Thomas KR, Capecchi MR. Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motoneurons. Development (Cambridge, England). 130: 5191-201. PMID 12954718 DOI: 10.1242/Dev.00730  1
2003 Wellik DM, Capecchi MR. Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton. Science (New York, N.Y.). 301: 363-7. PMID 12869760 DOI: 10.1126/science.1085672  1
2003 Arenkiel BR, Gaufo GO, Capecchi MR. Hoxb1 neural crest preferentially form glia of the PNS. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 227: 379-86. PMID 12815623 DOI: 10.1002/Dvdy.10323  1
2003 Economides KD, Zeltser L, Capecchi MR. Hoxb13 mutations cause overgrowth of caudal spinal cord and tail vertebrae. Developmental Biology. 256: 317-30. PMID 12679105 DOI: 10.1016/S0012-1606(02)00137-9  1
2003 Economides KD, Capecchi MR. Hoxb13 is required for normal differentiation and secretory function of the ventral prostate. Development (Cambridge, England). 130: 2061-9. PMID 12668621 DOI: 10.1242/Dev.00432  1
2003 Cole JM, Khokhlova N, Sutliff RL, Adams JW, Disher KM, Zhao H, Capecchi MR, Corvol P, Bernstein KE. Mice lacking endothelial ACE: normal blood pressure with elevated angiotensin II. Hypertension. 41: 313-21. PMID 12574101 DOI: 10.1161/01.Hyp.0000050650.52007.83  1
2003 Barrow JR, Thomas KR, Boussadia-Zahui O, Moore R, Kemler R, Capecchi MR, McMahon AP. Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes & Development. 17: 394-409. PMID 12569130 DOI: 10.1101/Gad.1044903  1
2003 Schmidt EE, Bondareva AA, Radke JR, Capecchi MR. Fundamental cellular processes do not require vertebrate-specific sequences within the TATA-binding protein. The Journal of Biological Chemistry. 278: 6168-74. PMID 12471023 DOI: 10.1074/Jbc.M211205200  1
2002 Vorbach C, Scriven A, Capecchi MR. The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland. Genes & Development. 16: 3223-35. PMID 12502743 DOI: 10.1101/gad.1032702  1
2002 Frank DU, Fotheringham LK, Brewer JA, Muglia LJ, Tristani-Firouzi M, Capecchi MR, Moon AM. An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome. Development (Cambridge, England). 129: 4591-603. PMID 12223415  1
2002 Boulet AM, Capecchi MR. Duplication of the Hoxd11 gene causes alterations in the axial and appendicular skeleton of the mouse. Developmental Biology. 249: 96-107. PMID 12217321 DOI: 10.1006/dbio.2002.0755  1
2002 Hobbs NK, Bondareva AA, Barnett S, Capecchi MR, Schmidt EE. Removing the vertebrate-specific TBP N terminus disrupts placental beta2m-dependent interactions with the maternal immune system. Cell. 110: 43-54. PMID 12150996 DOI: 10.1016/S0092-8674(02)00806-1  1
2002 Wellik DM, Hawkes PJ, Capecchi MR. Hox11 paralogous genes are essential for metanephric kidney induction. Genes & Development. 16: 1423-32. PMID 12050119 DOI: 10.1101/gad.993302  1
2002 Cole J, Quach DL, Sundaram K, Corvol P, Capecchi MR, Bernstein KE. Mice lacking endothelial angiotensin-converting enzyme have a normal blood pressure. Circulation Research. 90: 87-92. PMID 11786523 DOI: 10.1161/Hh0102.102360  1
2002 Greer JM, Capecchi MR. Hoxb8 is required for normal grooming behavior in mice. Neuron. 33: 23-34. PMID 11779477 DOI: 10.1016/S0896-6273(01)00564-5  1
2001 Stadler HS, Higgins KM, Capecchi MR. Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs. Development (Cambridge, England). 128: 4177-88. PMID 11684655  1
2001 Capecchi MR. Generating mice with targeted mutations. Nature Medicine. 7: 1086-90. PMID 11590420 DOI: 10.1038/nm1001-1086  1
2001 Manley NR, Barrow JR, Zhang T, Capecchi MR. Hoxb2 and hoxb4 act together to specify ventral body wall formation. Developmental Biology. 237: 130-44. PMID 11518511 DOI: 10.1006/Dbio.2001.0365  1
2000 Cole J, Ertoy D, Lin H, Sutliff RL, Ezan E, Guyene TT, Capecchi M, Corvol P, Bernstein KE. Lack of angiotensin II-facilitated erythropoiesis causes anemia in angiotensin-converting enzyme-deficient mice Journal of Clinical Investigation. 106: 1391-1398. PMID 11104792 DOI: 10.1172/Jci10557  1
2000 Moon AM, Capecchi MR. Fgf8 is required for outgrowth and patterning of the limbs. Nature Genetics. 26: 455-9. PMID 11101845 DOI: 10.1038/82601  1
2000 Schmidt EE, Taylor DS, Prigge JR, Barnett S, Capecchi MR. Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids. Proceedings of the National Academy of Sciences of the United States of America. 97: 13702-7. PMID 11087830 DOI: 10.1073/Pnas.240471297  1
2000 Gaufo GO, Flodby P, Capecchi MR. Hoxb1 controls effectors of sonic hedgehog and Mash1 signaling pathways. Development (Cambridge, England). 127: 5343-54. PMID 11076756  1
2000 Capecchi MR. Choose your target. Nature Genetics. 26: 159-61. PMID 11017070 DOI: 10.1038/82825  1
2000 Greer JM, Puetz J, Thomas KR, Capecchi MR. Maintenance of functional equivalence during paralogous Hox gene evolution. Nature. 403: 661-5. PMID 10688203 DOI: 10.1038/35001077  1
2000 Moon AM, Boulet AM, Capecchi MR. Normal limb development in conditional mutants of Fgf4. Development (Cambridge, England). 127: 989-96. PMID 10662638  1
2000 Barrow JR, Stadler HS, Capecchi MR. Roles of Hoxa1 and Hoxa2 in patterning the early hindbrain of the mouse. Development (Cambridge, England). 127: 933-44. PMID 10662633  1
2000 Capecchi MR. How close are we to implementing gene targeting in animals other than the mouse? Proceedings of the National Academy of Sciences of the United States of America. 97: 956-7. PMID 10655465 DOI: 10.1073/pnas.97.3.956  1
1999 Godwin AR, Capecchi MR. Hair defects in Hoxc13 mutant mice. The Journal of Investigative Dermatology. Symposium Proceedings / the Society For Investigative Dermatology, Inc. [and] European Society For Dermatological Research. 4: 244-7. PMID 10674376 DOI: 10.1038/Sj.Jidsp.5640221  1
1999 Hashimoto J, Murakami G, Tsugane MH, Chisaka O, Capecchi MR, Ogino T. Lumbosacral plexus in Hoxa9 knockout mice with special reference to their nerve variations identified according to whether they were interphenotypic or intergenotypic differences. Kaibogaku Zasshi. Journal of Anatomy. 74: 609-30. PMID 10659578  1
1999 Rossel M, Capecchi MR. Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development (Cambridge, England). 126: 5027-40. PMID 10529420  1
1999 Barrow JR, Capecchi MR. Compensatory defects associated with mutations in Hoxa1 restore normal palatogenesis to Hoxa2 mutants. Development (Cambridge, England). 126: 5011-26. PMID 10529419  1
1999 Bunting M, Bernstein KE, Greer JM, Capecchi MR, Thomas KR. Targeting genes for self-excision in the germ line. Genes & Development. 13: 1524-8. PMID 10385621 DOI: 10.1101/Gad.13.12.1524  1
1999 Schmidt EE, Hanson ES, Capecchi MR. Sequence-independent assembly of spermatid mRNAs into messenger ribonucleoprotein particles. Molecular and Cellular Biology. 19: 3904-15. PMID 10207114 DOI: 10.1128/MCB.19.5.3904  1
1999 Chen F, Capecchi MR. Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy. Proceedings of the National Academy of Sciences of the United States of America. 96: 541-6. PMID 9892669 DOI: 10.1073/pnas.96.2.541  1
1998 Godwin AR, Stadler HS, Nakamura K, Capecchi MR. Detection of targeted GFP-Hox gene fusions during mouse embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 95: 13042-7. PMID 9789037 DOI: 10.1073/pnas.95.22.13042  1
1998 Chen F, Greer J, Capecchi MR. Analysis of Hoxa7/Hoxb7 mutants suggests periodicity in the generation of the different sets of vertebrae. Mechanisms of Development. 77: 49-57. PMID 9784603 DOI: 10.1016/S0925-4773(98)00126-9  1
1998 Manley NR, Capecchi MR. Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands. Developmental Biology. 195: 1-15. PMID 9520319 DOI: 10.1006/Dbio.1997.8827  1
1998 Hostikka SL, Capecchi MR. The mouse Hoxc11 gene: genomic structure and expression pattern. Mechanisms of Development. 70: 133-45. PMID 9510030 DOI: 10.1016/S0925-4773(97)00182-2  1
1998 Godwin AR, Capecchi MR. Hoxc13 mutant mice lack external hair. Genes & Development. 12: 11-20. PMID 9420327 DOI: 10.1101/Gad.12.1.11  1
1997 Capecchi MR. Hox genes and mammalian development. Cold Spring Harbor Symposia On Quantitative Biology. 62: 273-81. PMID 9598361 DOI: 10.1101/Sqb.1997.062.01.034  1
1997 Wilder PJ, Kelly D, Brigman K, Peterson CL, Nowling T, Gao QS, McComb RD, Capecchi MR, Rizzino A. Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny. Developmental Biology. 192: 614-29. PMID 9441693 DOI: 10.1006/Dbio.1997.8777  1
1997 Manley NR, Capecchi MR. Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. Developmental Biology. 192: 274-88. PMID 9441667 DOI: 10.1006/Dbio.1997.8765  1
1997 Carpenter EM, Goddard JM, Davis AP, Nguyen TP, Capecchi MR. Targeted disruption of Hoxd-10 affects mouse hindlimb development. Development (Cambridge, England). 124: 4505-14. PMID 9409668  1
1997 Condie BG, Bain G, Gottlieb DI, Capecchi MR. Cleft palate in mice with a targeted mutation in the gamma-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67. Proceedings of the National Academy of Sciences of the United States of America. 94: 11451-5. PMID 9326630 DOI: 10.1073/Pnas.94.21.11451  1
1997 Esther CR, Marino EM, Howard TE, Machaud A, Corvol P, Capecchi MR, Bernstein KE. The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice. The Journal of Clinical Investigation. 99: 2375-85. PMID 9153279 DOI: 10.1172/Jci119419  1
1997 Thomas KR, Capecchi MR. Recombinant DNA technique and sickle cell anemia research. Science (New York, N.Y.). 275: 1404-5. PMID 9072801 DOI: 10.1126/science.275.5305.1401e  1
1997 Humphries MM, Rancourt D, Farrar GJ, Kenna P, Hazel M, Bush RA, Sieving PA, Sheils DM, McNally N, Creighton P, Erven A, Boros A, Gulya K, Capecchi MR, Humphries P. Retinopathy induced in mice by targeted disruption of the rhodopsin gene. Nature Genetics. 15: 216-9. PMID 9020854 DOI: 10.1038/ng0297-216  1
1997 Chen F, Capecchi MR. Targeted mutations in hoxa-9 and hoxb-9 reveal synergistic interactions. Developmental Biology. 181: 186-96. PMID 9013929 DOI: 10.1006/dbio.1996.8440  1
1996 Barrow JR, Capecchi MR. Targeted disruption of the Hoxb-2 locus in mice interferes with expression of Hoxb-1 and Hoxb-4. Development (Cambridge, England). 122: 3817-28. PMID 9012503  1
1996 Esther CR, Howard TE, Zhou Y, Capecchi MR, Marrero MB, Bernstein KE. Lessons from angiotensin-converting enzyme-deficient mice. Current Opinion in Nephrology and Hypertension. 5: 463-7. PMID 8978990 DOI: 10.1097/00041552-199611000-00001  1
1996 Goddard JM, Rossel M, Manley NR, Capecchi MR. Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve. Development (Cambridge, England). 122: 3217-28. PMID 8898234  1
1996 Delort JP, Capecchi MR. TAXI/UAS: A molecular switch to control expression of genes in vivo. Human Gene Therapy. 7: 809-20. PMID 8860833 DOI: 10.1089/hum.1996.7.7-809  1
1996 Capecchi MR. Function of homeobox genes in skeletal development. Annals of the New York Academy of Sciences. 785: 34-7. PMID 8702174 DOI: 10.1111/J.1749-6632.1996.Tb56241.X  1
1996 Boulet AM, Capecchi MR. Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations. Developmental Biology. 177: 232-49. PMID 8660891 DOI: 10.1006/dbio.1996.0159  1
1996 Esther CR, Howard TE, Marino EM, Goddard JM, Capecchi MR, Bernstein KE. Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. Laboratory Investigation; a Journal of Technical Methods and Pathology. 74: 953-65. PMID 8642790  1
1996 Davis AP, Capecchi MR. A mutational analysis of the 5' HoxD genes: dissection of genetic interactions during limb development in the mouse. Development (Cambridge, England). 122: 1175-85. PMID 8620844  1
1995 Rancourt DE, Tsuzuki T, Capecchi MR. Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation. Genes & Development. 9: 108-22. PMID 7828847 DOI: 10.1101/Gad.9.1.108  1
1995 Manley NR, Capecchi MR. The role of Hoxa-3 in mouse thymus and thyroid development. Development (Cambridge, England). 121: 1989-2003. PMID 7635047  1
1995 Davis AP, Witte DP, Hsieh-Li HM, Potter SS, Capecchi MR. Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11. Nature. 375: 791-5. PMID 7596412 DOI: 10.1038/375791a0  1
1995 Zeiher BG, Eichwald E, Zabner J, Smith JJ, Puga AP, McCray PB, Capecchi MR, Welsh MJ, Thomas KR. A mouse model for the delta F508 allele of cystic fibrosis. The Journal of Clinical Investigation. 96: 2051-64. PMID 7560099 DOI: 10.1172/Jci118253  1
1995 Capecchi MR. Introduction: The molecular genetic analysis of mouse development Seminars in Developmental Biology. 6: 233-236.  1
1994 Capecchi MR. Targeted gene replacement. Scientific American. 270: 52-9. PMID 8134827 DOI: 10.1038/Scientificamerican0394-52  1
1994 Spyropoulos DD, Capecchi MR. Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus. Genes & Development. 8: 1949-61. PMID 7958869 DOI: 10.1101/Gad.8.16.1949  1
1994 Davis AP, Capecchi MR. Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. Development (Cambridge, England). 120: 2187-98. PMID 7925020  1
1994 Kostic D, Capecchi MR. Targeted disruptions of the murine Hoxa-4 and Hoxa-6 genes result in homeotic transformations of components of the vertebral column. Mechanisms of Development. 46: 231-47. PMID 7918106 DOI: 10.1016/0925-4773(94)90073-6  1
1994 Condie BG, Capecchi MR. Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions. Nature. 370: 304-7. PMID 7913519 DOI: 10.1038/370304A0  1
1993 Deng C, Thomas KR, Capecchi MR. Location of crossovers during gene targeting with insertion and replacement vectors. Molecular and Cellular Biology. 13: 2134-40. PMID 8455602 DOI: 10.1128/MCB.13.4.2134  1
1993 Mansour SL, Goddard JM, Capecchi MR. Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development (Cambridge, England). 117: 13-28. PMID 8223243  1
1993 Capecchi MR. Mouse genetics. YACs to the rescue. Nature. 362: 205-6. PMID 8096325 DOI: 10.1038/362205a0  1
1993 Condie BG, Capecchi MR. Mice homozygous for a targeted disruption of Hoxd-3 (Hox-4.1) exhibit anterior transformations of the first and second cervical vertebrae, the atlas and the axis. Development (Cambridge, England). 119: 579-95. PMID 7910549  1
1993 Carpenter EM, Goddard JM, Chisaka O, Manley NR, Capecchi MR. Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the murine hindbrain. Development (Cambridge, England). 118: 1063-75. PMID 7903632  1
1992 Thomas KR, Deng C, Capecchi MR. High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. Molecular and Cellular Biology. 12: 2919-23. PMID 1620105 DOI: 10.1128/MCB.12.7.2919  1
1992 Chisaka O, Musci TS, Capecchi MR. Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6. Nature. 355: 516-20. PMID 1346922 DOI: 10.1038/355516a0  1
1992 Deng C, Capecchi MR. Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Molecular and Cellular Biology. 12: 3365-71. PMID 1321331 DOI: 10.1128/Mcb.12.8.3365  1
1991 Thomas KR, Musci TS, Neumann PE, Capecchi MR. Swaying is a mutant allele of the proto-oncogene Wnt-1. Cell. 67: 969-76. PMID 1835670 DOI: 10.1016/0092-8674(91)90369-A  1
1991 Chisaka O, Capecchi MR. Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. Nature. 350: 473-9. PMID 1673020 DOI: 10.1038/350473a0  1
1990 Thomas KR, Capecchi MR. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature. 346: 847-50. PMID 2202907 DOI: 10.1038/346847a0  1
1990 Mansour SL, Thomas KR, Deng CX, Capecchi MR. Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 87: 7688-92. PMID 2120706 DOI: 10.1073/Pnas.87.19.7688  1
1989 Franklin NC, Davern CI, Goldenberg D, Capecchi MR, Gurney T, Gurney E, Hazelrigg T, Casjens SR, Herrick GS, Ehrenfeld E, Low D, Buchi KN, Ash JF. Petition on Dugway facility [2] Science. 243: 11-12. PMID 2911712  1
1989 Capecchi MR. The new mouse genetics: altering the genome by gene targeting. Trends in Genetics : Tig. 5: 70-6. PMID 2660363 DOI: 10.1016/0168-9525(89)90029-2  1
1989 Capecchi MR. Altering the genome by homologous recombination. Science (New York, N.Y.). 244: 1288-92. PMID 2660260 DOI: 10.1126/Science.2660260  1
1988 Mansour SL, Thomas KR, Capecchi MR. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature. 336: 348-52. PMID 3194019 DOI: 10.1038/336348A0  1
1987 Wong EA, Capecchi MR. Homologous recombination between coinjected DNA sequences peaks in early to mid-S phase. Molecular and Cellular Biology. 7: 2294-5. PMID 3600663 DOI: 10.1128/Mcb.7.6.2294  1
1987 Thomas KR, Capecchi MR. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell. 51: 503-12. PMID 2822260 DOI: 10.1016/0092-8674(87)90646-5  1
1986 Thomas KR, Capecchi MR. Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene. Nature. 324: 34-8. PMID 3785372 DOI: 10.1038/324034a0  1
1986 Thomas KR, Capecchi MR. Targeting of genes to specific sites in the mammalian genome. Cold Spring Harbor Symposia On Quantitative Biology. 51: 1101-13. PMID 3472755 DOI: 10.1101/SQB.1986.051.01.128  1
1986 Goddard JM, Weiland JJ, Capecchi MR. Isolation and characterization of Caenorhabditis elegans DNA sequences homologous to the v-abl oncogene. Proceedings of the National Academy of Sciences of the United States of America. 83: 2172-6. PMID 3457381 DOI: 10.1073/Pnas.83.7.2172  1
1986 Wong EA, Capecchi MR. Analysis of homologous recombination in cultured mammalian cells in transient expression and stable transformation assays. Somatic Cell and Molecular Genetics. 12: 63-72. PMID 3003931 DOI: 10.1007/BF01560728  1
1986 Thomas KR, Folger KR, Capecchi MR. High frequency targeting of genes to specific sites in the mammalian genome. Cell. 44: 419-28. PMID 3002636 DOI: 10.1016/0092-8674(86)90463-0  1
1985 Folger KR, Thomas K, Capecchi MR. Efficient correction of mismatched bases in plasmid heteroduplexes injected into cultured mammalian cell nuclei. Molecular and Cellular Biology. 5: 70-4. PMID 3982420 DOI: 10.1128/Mcb.5.1.70  1
1985 Frels WI, Bluestone JA, Hodes RJ, Capecchi MR, Singer DS. Expression of a microinjected porcine class I major histocompatibility complex gene in transgenic mice. Science (New York, N.Y.). 228: 577-80. PMID 3885396 DOI: 10.1126/Science.3885396  1
1985 Wong EA, Capecchi MR. Effect of cell cycle position on transformation by microinjection. Somatic Cell and Molecular Genetics. 11: 43-51. PMID 3856330 DOI: 10.1007/BF01534733  1
1985 Folger KR, Thomas K, Capecchi MR. Nonreciprocal exchanges of information between DNA duplexes coinjected into mammalian cell nuclei. Molecular and Cellular Biology. 5: 59-69. PMID 2984556 DOI: 10.1128/Mcb.5.1.59  1
1984 Folger K, Thomas K, Capecchi MR. Analysis of homologous recombination in cultured mammalian cells. Cold Spring Harbor Symposia On Quantitative Biology. 49: 123-38. PMID 6099232 DOI: 10.1101/Sqb.1984.049.01.016  1
1984 Laski FA, Belagaje R, Hudziak RM, Capecchi MR, Norton GP, Palese P, RajBhandary UL, Sharp PA. Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells. The Embo Journal. 3: 2445-52. PMID 6096120 DOI: 10.1002/J.1460-2075.1984.Tb02154.X  1
1983 Young JF, Capecchi M, Laski FA, RajBhandary UL, Sharp PA, Palese P. Measurement of suppressor transfer RNA activity. Science (New York, N.Y.). 221: 873-5. PMID 6308765 DOI: 10.1126/Science.6308765  1
1983 Luciw PA, Bishop JM, Varmus HE, Capecchi MR. Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA. Cell. 33: 705-16. PMID 6307525 DOI: 10.1016/0092-8674(83)90013-2  1
1982 Hudziak RM, Laski FA, RajBhandary UL, Sharp PA, Capecchi MR. Establishment of mammalian cell lines containing multiple nonsense mutations and functional suppressor tRNA genes. Cell. 31: 137-46. PMID 6760983 DOI: 10.1016/0092-8674(82)90413-5  1
1982 Folger KR, Wong EA, Wahl G, Capecchi MR. Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules. Molecular and Cellular Biology. 2: 1372-87. PMID 6298598 DOI: 10.1128/Mcb.2.11.1372  1
1980 Capecchi MR. High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell. 22: 479-88. PMID 6256082 DOI: 10.1016/0092-8674(80)90358-X  1
1977 Capecchi MR, Haar RA, Capecchi NE, Sveda MM. The isolation of a suppressible nonsense mutant in mammalian cells. Cell. 12: 371-81. PMID 912748 DOI: 10.1016/0092-8674(77)90113-1  1
1975 Capecchi MR, Hughes SH, Wahl GM. Yeast super-suppressors are altered tRNAs capable of translating a nonsense codon in vitro. Cell. 6: 269-77. PMID 802681 DOI: 10.1016/0092-8674(75)90178-6  1
1975 Hughes SH, Wahl GM, Capecchi MR. Purification and characterization of mouse hypoxanthine-guanine phosphoribosyltransferase. The Journal of Biological Chemistry. 250: 120-6. PMID 237883  1
1975 Wahl GM, Hughes SH, Capecchi MR. Immunological characterization of hypoxanthine-guanine phosphoribosyl transferase mutants of mouse L cells: evidence for mutations at different loci in the HGPRT gene. Journal of Cellular Physiology. 85: 307-20. PMID 47331 DOI: 10.1002/Jcp.1040850217  1
1974 Capecchi MR, Capecchi NE, Hughes SH, Wahl GM. Selective degradation of abnormal proteins in mammalian tissue culture cells. Proceedings of the National Academy of Sciences of the United States of America. 71: 4732-6. PMID 4531013 DOI: 10.1073/Pnas.71.12.4732  0.52
1966 Adams JM, Capecchi MR. N-formylmethionyl-sRNA as the initiator of protein synthesis. Proceedings of the National Academy of Sciences of the United States of America. 55: 147-55. PMID 5328638 DOI: 10.1073/Pnas.55.1.147  1
1966 Gussin GN, Capecchi MR, Adams JM, Argetsinger JE, Tooze J, Weber K, Watson JD. Protein synthesis directed by DNA phage messengers. Cold Spring Harbor Symposia On Quantitative Biology. 31: 157-71. PMID 4866373 DOI: 10.1101/Sqb.1966.031.01.034  0.8
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