Tom Povsic - Publications

Affiliations: 
Duke University, Durham, NC 

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Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
2003 Povsic TJ, Kohout TA, Lefkowitz RJ. Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis. The Journal of Biological Chemistry. 278: 51334-9. PMID 14534298 DOI: 10.1074/jbc.M309968200  0.218
2013 Becker RC, Chan MY, Vavalle JP, Povsic TJ. Anticoagulation and monitoring of a novel and reversible factor IXa inhibitor Drug Development Research. 74: 510-516. DOI: 10.1002/ddr.21109  0.158
2008 Zhu S, Evans S, Yan B, Povsic TJ, Tapson V, Goldschmidt-Clermont PJ, Dong C. Transcriptional regulation of Bim by FOXO3a and Akt mediates scleroderma serum-induced apoptosis in endothelial progenitor cells. Circulation. 118: 2156-65. PMID 18981303 DOI: 10.1161/Circulationaha.108.787200  0.146
2016 Povsic TJ, Roe MT, Ohman EM, Steg PG, James S, Plotnikov A, Mundl H, Welsh R, Bode C, Gibson CM. A randomized trial to compare the safety of rivaroxaban vs aspirin in addition to either clopidogrel or ticagrelor in acute coronary syndrome: The design of the GEMINI-ACS-1 phase II study. American Heart Journal. 174: 120-8. PMID 26995378 DOI: 10.1016/j.ahj.2016.01.004  0.143
2016 Nimjee SM, Povsic TJ, Sullenger BA, Becker RC. Translation and Clinical Development of Antithrombotic Aptamers. Nucleic Acid Therapeutics. PMID 26882082 DOI: 10.1089/Nat.2015.0581  0.14
2013 Povsic TJ, Junge C, Nada A, Schatz RA, Harrington RA, Davidson CJ, Fortuin FD, Kereiakes DJ, Mendelsohn FO, Sherman W, Schaer GL, White CJ, Stewart D, Story K, Losordo DW, et al. A phase 3, randomized, double-blinded, active-controlled, unblinded standard of care study assessing the efficacy and safety of intramyocardial autologous CD34+ cell administration in patients with refractory angina: design of the RENEW study. American Heart Journal. 165: 854-861.e2. PMID 23708155 DOI: 10.1016/j.ahj.2013.03.003  0.131
2010 Povsic TJ, Sullenger BA, Zelenkofske SL, Rusconi CP, Becker RC. Translating nucleic acid aptamers to antithrombotic drugs in cardiovascular medicine. Journal of Cardiovascular Translational Research. 3: 704-16. PMID 21080135 DOI: 10.1007/S12265-010-9230-6  0.13
2020 Shavadia JS, Granger CB, Alemayehu W, Westerhout CM, Povsic TJ, Van Diepen S, Defilippi C, Armstrong PW. Novel Biomarkers, ST-Elevation Resolution, and Clinical Outcomes Following Primary Percutaneous Coronary Intervention. Journal of the American Heart Association. e016033. PMID 32552321 DOI: 10.1161/JAHA.120.016033  0.126
2018 Fanaroff AC, Morrow V, Krucoff MW, Seltzer JH, Perin EC, Taylor DA, Miller LW, Zeiher AM, Fernández-Avilés F, Losordo DW, Henry TD, Povsic TJ. A Path Forward for Regenerative Medicine. Circulation Research. 123: 495-505. PMID 30355250 DOI: 10.1161/Circresaha.118.313261  0.125
2020 von Lewinski D, Selvanayagam JB, Schatz RA, Jilma B, Kubica J, Povsic TJ, Nix D, Henauer S, Wallner M. "Protocol for a phase 2, randomized, double-blind, placebo-controlled, safety and efficacy study of dutogliptin in combination with filgrastim in early recovery post-myocardial infarction": study protocol for a randomized controlled trial. Trials. 21: 744. PMID 32843081 DOI: 10.1186/s13063-020-04652-0  0.121
2011 Povsic TJ, Wargin WA, Alexander JH, Krasnow J, Krolick M, Cohen MG, Mehran R, Buller CE, Bode C, Zelenkofske SL, Rusconi CP, Becker RC. Pegnivacogin results in near complete FIX inhibition in acute coronary syndrome patients: RADAR pharmacokinetic and pharmacodynamic substudy. European Heart Journal. 32: 2412-9. PMID 21724623 DOI: 10.1093/eurheartj/ehr179  0.119
2010 Povsic TJ, O'Connor CM. Cell therapy for heart failure: the need for a new therapeutic strategy. Expert Review of Cardiovascular Therapy. 8: 1107-26. PMID 20670189 DOI: 10.1586/erc.10.99  0.119
2005 Povsic TJ, Peterson ED. Progenitor cell therapy of ischemic heart disease: the new frontier. Future Cardiology. 1: 87-98. PMID 19804064 DOI: 10.1517/14796678.1.1.87  0.111
1994 Gallo RL, Ono M, Povsic T, Page C, Eriksson E, Klagsbrun M, Bernfield M. Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds. Proceedings of the National Academy of Sciences of the United States of America. 91: 11035-9. PMID 7972004 DOI: 10.1073/Pnas.91.23.11035  0.111
2021 Povsic TJ, Henry TD, Ohman EM, Pepine CJ, Crystal RG, Rosengart TK, Reinhardt RR, Dittrich HC, Traverse JH, Answini GA, Mokadam NA. Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (The EXACT Trial): Rationale, Design, and Clinical Considerations. American Heart Journal. PMID 34224684 DOI: 10.1016/j.ahj.2021.06.013  0.11
2017 Ohman EM, Roe MT, Steg PG, James SK, Povsic TJ, White J, Rockhold F, Plotnikov A, Mundl H, Strony J, Sun X, Husted S, Tendera M, Montalescot G, Bahit MC, et al. Clinically significant bleeding with low-dose rivaroxaban versus aspirin, in addition to P2Y12 inhibition, in acute coronary syndromes (GEMINI-ACS-1): a double-blind, multicentre, randomised trial. Lancet (London, England). PMID 28325638 DOI: 10.1016/S0140-6736(17)30751-1  0.11
2011 Povsic TJ, Cohen MG, Mehran R, Buller CE, Bode C, Cornel JH, Kasprzak JD, Montalescot G, Joseph D, Wargin WA, Rusconi CP, Zelenkofske SL, Becker RC, Alexander JH. A randomized, partially blinded, multicenter, active-controlled, dose-ranging study assessing the safety, efficacy, and pharmacodynamics of the REG1 anticoagulation system in patients with acute coronary syndromes: design and rationale of the RADAR Phase IIb trial. American Heart Journal. 161: 261-268.e1-2. PMID 21315207 DOI: 10.1016/j.ahj.2010.10.022  0.106
2020 Makkar RR, Kereiakes DJ, Aguirre F, Kowalchuk G, Chakravarty T, Malliaras K, Francis GS, Povsic TJ, Schatz R, Traverse JH, Pogoda JM, Smith RR, Marbán L, Ascheim DD, Ostovaneh MR, et al. Intracoronary ALLogeneic heart STem cells to Achieve myocardial Regeneration (ALLSTAR): a randomized, placebo-controlled, double-blinded trial. European Heart Journal. PMID 32749459 DOI: 10.1093/eurheartj/ehaa541  0.105
2015 Lincoff AM, Mehran R, Povsic TJ, Zelenkofske SL, Huang Z, Armstrong PW, Steg PG, Bode C, Cohen MG, Buller C, Laanmets P, Valgimigli M, Marandi T, Fridrich V, Cantor WJ, et al. Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial. Lancet (London, England). PMID 26547100 DOI: 10.1016/S0140-6736(15)00515-2  0.105
2007 Povsic TJ, Zavodni KL, Kelly FL, Zhu S, Goldschmidt-Clermont PJ, Dong C, Peterson ED. Circulating progenitor cells can be reliably identified on the basis of aldehyde dehydrogenase activity. Journal of the American College of Cardiology. 50: 2243-8. PMID 18061073 DOI: 10.1016/J.Jacc.2007.08.033  0.103
2013 Povsic TJ, Vavalle JP, Aberle LH, Kasprzak JD, Cohen MG, Mehran R, Bode C, Buller CE, Montalescot G, Cornel JH, Rynkiewicz A, Ring ME, Zeymer U, Natarajan M, Delarche N, et al. A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial. European Heart Journal. 34: 2481-9. PMID 22859796 DOI: 10.1093/eurheartj/ehs232  0.102
2016 Chakravarty T, Makkar RR, Ascheim D, Traverse JH, Schatz R, DeMaria A, Francis GS, Povsic TJ, Smith R, Lima JA, Pogoda JM, Marbán L, Henry TD. ALLogeneic Heart STem Cells to Achieve Myocardial Regeneration (ALLSTAR) trial: Rationale & Design. Cell Transplantation. PMID 27543900 DOI: 10.3727/096368916X692933  0.102
2016 Fernandez CE, Yen RW, Perez SM, Bedell HW, Povsic TJ, Reichert WM, Truskey GA. Human Vascular Microphysiological System for in vitro Drug Screening. Scientific Reports. 6: 21579. PMID 26888719 DOI: 10.1038/Srep21579  0.102
2010 Melloni C, Rao SV, Povsic TJ, Melton L, Kim RJ, Kilaru R, Patel MR, Talan M, Ferrucci L, Longo DL, Lakatta EG, Najjar SS, Harrington RA. Design and rationale of the Reduction of Infarct Expansion and Ventricular Remodeling with Erythropoietin after Large Myocardial Infarction (REVEAL) trial. American Heart Journal. 160: 795-803.e2. PMID 21095264 DOI: 10.1016/j.ahj.2010.09.007  0.1
2016 Henry TD, Pepine C, Lambert C, Traverse JH, Schatz R, Costa M, Povsic TJ, Anderson RD, Kesten S, Perin EC. The Athena Trials: Autologous Adipose-Derived Regenerative Cells (ADRCs) for Refractory Chronic Myocardial Ischemia with Left Ventricular Dysfunction. Catheterization and Cardiovascular Interventions : Official Journal of the Society For Cardiac Angiography & Interventions. PMID 27148802 DOI: 10.1002/ccd.26601  0.099
2016 Welsh RC, Roe MT, Steg PG, James S, Povsic TJ, Bode C, Gibson CM, Ohman EM. A critical reappraisal of aspirin for secondary prevention in patients with ischemic heart disease. American Heart Journal. 181: 92-100. PMID 27823698 DOI: 10.1016/j.ahj.2016.08.008  0.099
2019 Normand C, Kaye DM, Povsic TJ, Dickstein K. Beyond pharmacological treatment: an insight into therapies that target specific aspects of heart failure pathophysiology. Lancet (London, England). 393: 1045-1055. PMID 30860030 DOI: 10.1016/S0140-6736(18)32216-5  0.098
2010 Becker RC, Povsic T, Cohen MG, Rusconi CP, Sullenger B. Nucleic acid aptamers as antithrombotic agents: Opportunities in extracellular therapeutics Thrombosis and Haemostasis. 103: 586-595. PMID 20135076 DOI: 10.1160/Th09-10-0716  0.097
2016 Bartunek J, Terzic A, Davison BA, Filippatos GS, Radovanovic S, Beleslin B, Merkely B, Musialek P, Wojakowski W, Andreka P, Horvath IG, Katz A, Dolatabadi D, El Nakadi B, Arandjelovic A, ... ... Povsic TJ, et al. Cardiopoietic cell therapy for advanced ischemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial. European Heart Journal. PMID 28025189 DOI: 10.1093/Eurheartj/Ehw543  0.094
2014 Vavalle JP, Rusconi CP, Zelenkofske S, Wargin WA, Ortel TL, Alexander JH, Povsic TJ, Becker RC. The effect of the REG2 Anticoagulation System on thrombin generation kinetics: a pharmacodynamic and pharmacokinetic first-in-human study. Journal of Thrombosis and Thrombolysis. 38: 275-84. PMID 24880800 DOI: 10.1007/s11239-014-1081-6  0.094
2011 Povsic TJ, O'Connor CM, Henry T, Taussig A, Kereiakes DJ, Fortuin FD, Niederman A, Schatz R, Spencer R, Owens D, Banks M, Joseph D, Roberts R, Alexander JH, Sherman W. A double-blind, randomized, controlled, multicenter study to assess the safety and cardiovascular effects of skeletal myoblast implantation by catheter delivery in patients with chronic heart failure after myocardial infarction. American Heart Journal. 162: 654-662.e1. PMID 21982657 DOI: 10.1016/J.Ahj.2011.07.020  0.093
2015 Povsic TJ, Broderick S, Anstrom KJ, Shaw LK, Ohman EM, Eisenstein EL, Smith PK, Alexander JH. Predictors of long-term clinical endpoints in patients with refractory angina. Journal of the American Heart Association. 4. PMID 25637344 DOI: 10.1161/Jaha.114.001287  0.093
2018 Povsic TJ. Emerging Therapies for Congestive Heart Failure. Clinical Pharmacology and Therapeutics. 103: 77-87. PMID 29044498 DOI: 10.1002/cpt.913  0.091
2009 Povsic TJ, Henry T, Taussig A, Kereiakis D, Fortuin FD, Niederman A, Schatz R, Spencer R, Owens D, Banks M, Joseph D, Roberts R, O'Connor CM, Sherman W. MARVEL-1; A Double-Blind, Randomized, Controlled, Multicenter Study to Assess The Safety And Cardiovascular Effects of Myocell™ Implantation by a Catheter Delivery System in Congestive Heart Failure Patients Post Myocardial Infarction(s) Journal of Cardiac Failure. 15: 814-815. DOI: 10.1016/J.Cardfail.2009.10.015  0.088
2021 Povsic TJ, Gersh BJ. Stem Cells in Cardiovascular Diseases: 30,000-Foot View. Cells. 10. PMID 33803227 DOI: 10.3390/cells10030600  0.087
2016 Bartunek J, Davison B, Sherman W, Povsic T, Henry TD, Gersh B, Metra M, Filippatos G, Hajjar R, Behfar A, Homsy C, Cotter G, Wijns W, Tendera M, Terzic A. Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial design. European Journal of Heart Failure. 18: 160-8. PMID 26662998 DOI: 10.1002/Ejhf.434  0.085
2013 Say EA, Melamud A, Esserman DA, Povsic TJ, Chavala SH. Comparative analysis of circulating endothelial progenitor cells in age-related macular degeneration patients using automated rare cell analysis (ARCA) and fluorescence activated cell sorting (FACS). Plos One. 8: e55079. PMID 23359346 DOI: 10.1371/journal.pone.0055079  0.085
2006 Povsic TJ, Peterson ED. Stem cells for the ischaemic heart. Expert Opinion On Biological Therapy. 6: 427-42. PMID 16610974 DOI: 10.1517/14712598.6.5.427  0.084
2011 Povsic TJ, Cohen MG, Chan MY, Zelenkofske SL, Wargin WA, Harrington RA, Alexander JH, Rusconi CP, Becker RC. Dose selection for a direct and selective factor IXa inhibitor and its complementary reversal agent: translating pharmacokinetic and pharmacodynamic properties of the REG1 system to clinical trial design. Journal of Thrombosis and Thrombolysis. 32: 21-31. PMID 21503856 DOI: 10.1007/s11239-011-0588-3  0.084
2013 Povsic TJ, Najjar SS, Prather K, Zhou J, Adams SD, Zavodni KL, Kelly F, Melton LG, Hasselblad V, Heitner JF, Raman SV, Barsness GW, Patel MR, Kim RJ, Lakatta EG, et al. EPC mobilization after erythropoietin treatment in acute ST-elevation myocardial infarction: the REVEAL EPC substudy. Journal of Thrombosis and Thrombolysis. 36: 375-83. PMID 23700090 DOI: 10.1007/s11239-013-0944-6  0.084
2020 Gilotra NA, Devore A, Hays A, Hahn V, Agunbiade TA, Chen R, Davis R, Satlin A, Povsic T, Kass D. Cardiac and Hemodynamic Effects of Acute Phosphodiesterase-1 Inhibition in Human Heart Failure Journal of Cardiac Failure. 26: S12. DOI: 10.1016/J.CARDFAIL.2020.09.042  0.082
2020 Ostovaneh MR, Makkar R, Ambale Venkatesh B, Ascheim D, Chakravarty T, Henry TD, Kowalchuk G, Aguirre FV, Kereiakes DJ, Povsic TJ, Schatz RA, TRAVERSE JH, Pogoda J, Smith RD, Marban LS, et al. Abstract 12730: Cardiosphere-derived Cells Improve Segmental Myocardial Circumferential Strain by Magnetic Resonance Imaging: Results From the Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration Study Circulation. 142. DOI: 10.1161/circ.142.suppl_3.12730  0.081
2012 Povsic TJ, Losordo DW, Story K, Junge CE, Schatz RA, Harrington RA, Henry TD. Incidence and clinical significance of cardiac biomarker elevation during stem cell mobilization, apheresis, and intramyocardial delivery American Heart Journal. 164: 689-e3. PMID 23137499 DOI: 10.1016/j.ahj.2012.06.022  0.081
2011 Losordo DW, Henry TD, Davidson C, Sup Lee J, Costa MA, Bass T, Mendelsohn F, Fortuin FD, Pepine CJ, Traverse JH, Amrani D, Ewenstein BM, Riedel N, Story K, Barker K, ... Povsic TJ, et al. Intramyocardial, autologous CD34+ cell therapy for refractory angina Circulation Research. 109: 428-436. PMID 21737787 DOI: 10.1161/CIRCRESAHA.111.245993  0.078
2017 Teerlink JR, Metra M, Filippatos GS, Davison BA, Bartunek J, Terzic A, Gersh BJ, Povsic TJ, Henry TD, Alexandre B, Homsy C, Edwards C, Seron A, Wijns W, Cotter G, et al. Benefit of cardiopoietic mesenchymal stem cell therapy on left ventricular remodelling: results from the Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) study. European Journal of Heart Failure. PMID 28560782 DOI: 10.1002/Ejhf.898  0.077
2019 Shavadia JS, Granger CB, Alemayehu W, Westerhout CM, Povsic TJ, Brener SJ, van Diepen S, Defilippi C, Armstrong PW. High-throughput targeted proteomics discovery approach and spontaneous reperfusion in ST-segment elevation myocardial infarction. American Heart Journal. 220: 137-144. PMID 31812755 DOI: 10.1016/j.ahj.2019.09.015  0.077
2013 Jones LW, Fels DR, West M, Allen JD, Broadwater G, Barry WT, Wilke LG, Masko E, Douglas PS, Dash RC, Povsic TJ, Peppercorn J, Marcom PK, Blackwell KL, Kimmick G, et al. Modulation of circulating angiogenic factors and tumor biology by aerobic training in breast cancer patients receiving neoadjuvant chemotherapy. Cancer Prevention Research (Philadelphia, Pa.). 6: 925-37. PMID 23842792 DOI: 10.1158/1940-6207.Capr-12-0416  0.077
2017 Welsh RC, Roe MT, Steg PG, James S, Povsic TJ, Bode C, Gibson CM, Ohman EM. Corrigendum to "A critical reappraisal of aspirin for secondary prevention in patients with ischemic heart disease" [Am Heart J 181 (2016) 92-100]. American Heart Journal. 184: 156. PMID 28224931 DOI: 10.1016/j.ahj.2017.01.004  0.075
2020 Bartunek J, Terzic A, Davison BA, Behfar A, Sanz-Ruiz R, Wojakowski W, Sherman W, Heyndrickx GR, Metra M, Filippatos GS, Waldman SA, Teerlink JR, Henry TD, Gersh BJ, Hajjar R, ... ... Povsic TJ, et al. Cardiopoietic stem cell therapy in ischaemic heart failure: long-term clinical outcomes. Esc Heart Failure. PMID 33094909 DOI: 10.1002/ehf2.13031  0.075
2011 Najjar SS, Rao SV, Melloni C, Raman SV, Povsic TJ, Melton L, Barsness GW, Prather K, Heitner JF, Kilaru R, Gruberg L, Hasselblad V, Greenbaum AB, Patel M, Kim RJ, et al. Intravenous erythropoietin in patients with ST-segment elevation myocardial infarction: REVEAL: a randomized controlled trial. Jama. 305: 1863-72. PMID 21558517 DOI: 10.1001/jama.2011.592  0.072
2014 Povsic TJ, Vavalle JP, Alexander JH, Aberle LH, Zelenkofske SL, Becker RC, Buller CE, Cohen MG, Cornel JH, Kasprzak JD, Montalescot G, Fail PS, Sarembock IJ, Mehran R. Use of the REG1 anticoagulation system in patients with acute coronary syndromes undergoing percutaneous coronary intervention: results from the phase II RADAR-PCI study. Eurointervention : Journal of Europcr in Collaboration With the Working Group On Interventional Cardiology of the European Society of Cardiology. 10: 431-8. PMID 24929350 DOI: 10.4244/EIJY14M06_01  0.072
2021 Januzzi JL, Canty JM, Das S, DeFilippi CR, Gintant GA, Gutstein DE, Jaffe A, Kaushik EP, Leptak C, Mehta C, Pina I, Povsic TJ, Rambaran C, Rhyne RF, Salas M, et al. Gaining Efficiency in Clinical Trials With Cardiac Biomarkers: JACC Review Topic of the Week. Journal of the American College of Cardiology. 77: 1922-1933. PMID 33858628 DOI: 10.1016/j.jacc.2021.02.040  0.069
2021 Povsic TJ, Sanz-Ruiz R, Climent AM, Bolli R, Taylor DA, Gersh BJ, Menasché P, Perin EC, Pompilio G, Atsma DE, Badimon L, DeMaria AN, Hare JM, Henry TD, Janssens S, et al. Reparative cell therapy for the heart: critical internal appraisal of the field in response to recent controversies. Esc Heart Failure. PMID 33652498 DOI: 10.1002/ehf2.13256  0.069
2021 Povsic TJ, Henry TD, Ohman EM. Therapeutic Approaches for the No-Option Refractory Angina Patient. Circulation. Cardiovascular Interventions. CIRCINTERVENTIONS120. PMID 33541098 DOI: 10.1161/CIRCINTERVENTIONS.120.009002  0.069
2019 Povsic TJ, Ohman EM, Roe MT, White J, Rockhold FW, Montalescot G, Cornel JH, Nicolau JC, Steg PG, James S, Bode C, Welsh RC, Plotnikov AN, Mundl H, Gibson CM. P2Y12 Inhibitor Switching in Response to Routine Notification of CYP2C19 Clopidogrel Metabolizer Status Following Acute Coronary Syndromes. Jama Cardiology. PMID 31141104 DOI: 10.1001/jamacardio.2019.1510  0.069
2008 Povsic TJ, Goldschmidt-Clermont PJ. Endothelial progenitor cells: markers of vascular reparative capacity. Therapeutic Advances in Cardiovascular Disease. 2: 199-213. PMID 19124422 DOI: 10.1177/1753944708093412  0.068
2018 Fanaroff AC, Clare R, Pieper KS, Mahaffey KW, Melloni C, Green J, Alexander JH, Jones WS, Harrison RW, Mehta RH, Povsic TJ, Moreira HG, Al-Khatib SM, Roe MT, Kong DF, et al. Frequency, Regional Variation, and Predictors of Undetermined Cause of Death in Cardiometabolic Clinical Trials: A Pooled Analysis of 9,259 Deaths in 9 Trials. Circulation. PMID 30586739 DOI: 10.1161/CIRCULATIONAHA.118.037202  0.068
2013 Vavalle JP, Povsic TJ, Aberle LH, Zelenkofske SL, Mehran R, Kasprzak JD, Bode C, Buller CE, Montalescot G, Cornel JH, Becker RC, Alexander JH, Cohen MG. Safety of very early sheath removal in patients treated with REG1 for acute coronary syndromes: insights from the RADAR trial. The Journal of Invasive Cardiology. 25: 593-9. PMID 24184894  0.067
2018 Henry TD, Losordo DW, Traverse JH, Schatz RA, Jolicoeur EM, Schaer GL, Clare R, Chiswell K, White CJ, Fortuin FD, Kereiakes DJ, Zeiher AM, Sherman W, Hunt AS, Povsic TJ. Autologous CD34+ cell therapy improves exercise capacity, angina frequency and reduces mortality in no-option refractory angina: a patient-level pooled analysis of randomized double-blinded trials. European Heart Journal. PMID 29315376 DOI: 10.1093/eurheartj/ehx764  0.067
2015 Henry TD, Povsic TJ. Repeat Cell Therapy for Refractory Angina: Déjà vu All Over Again? Circulation. Cardiovascular Interventions. 8. PMID 26259771 DOI: 10.1161/CIRCINTERVENTIONS.115.003049  0.066
2012 Inrig JK, Van Buren P, Kim C, Vongpatanasin W, Povsic TJ, Toto R. Probing the mechanisms of intradialytic hypertension: a pilot study targeting endothelial cell dysfunction. Clinical Journal of the American Society of Nephrology : Cjasn. 7: 1300-9. PMID 22700888 DOI: 10.2215/CJN.10010911  0.066
2019 Shavadia J, Granger CB, Alemayehu W, Westerhout C, Povsic T, Brener S, DeFilippi C, Armstrong P. IDENTIFYING BIOMARKERS INDEPENDENTLY ASSOCIATED WITH SPONTANEOUS REPERFUSION IN ST ELEVATION MYOCARDIAL INFARCTION Journal of the American College of Cardiology. 73: 234. DOI: 10.1016/S0735-1097(19)30842-3  0.064
2020 Johnson GL, Henry TD, Povsic TJ, Losordo DW, Garberich RF, Stanberry LI, Strauss CE, Traverse JH. CD34 Cell Therapy Significantly Reduces Adverse Cardiac Events, Health Care Expenditures, and Mortality in Patients with Refractory Angina. Stem Cells Translational Medicine. PMID 32531108 DOI: 10.1002/sctm.20-0046  0.063
2016 Povsic TJ, Henry TD, Traverse JH, Fortuin FD, Schaer GL, Kereiakes DJ, Schatz RA, Zeiher AM, White CJ, Stewart DJ, Jolicoeur EM, Bass T, Henderson DA, Dignacco P, Gu Z, et al. The RENEW Trial: Efficacy and Safety of Intramyocardial Autologous CD34(+) Cell Administration in Patients With Refractory Angina. Jacc. Cardiovascular Interventions. 9: 1576-85. PMID 27491607 DOI: 10.1016/j.jcin.2016.05.003  0.063
2009 Stroncek JD, Grant BS, Brown MA, Povsic TJ, Truskey GA, Reichert WM. Comparison of endothelial cell phenotypic markers of late-outgrowth endothelial progenitor cells isolated from patients with coronary artery disease and healthy volunteers. Tissue Engineering. Part A. 15: 3473-86. PMID 19435420 DOI: 10.1089/Ten.Tea.2008.0673  0.062
2016 Povsic TJ. Current State of Stem Cell Therapy for Ischemic Heart Disease. Current Cardiology Reports. 18: 17. PMID 26768743 DOI: 10.1007/s11886-015-0693-6  0.061
2017 Chung MJ, Hansen JD, Schulteis RD, Boggan JC, Jones WS, Povsic TJ, Roberts S, Krucoff MW, Rao SV. Understanding operator stent choice in the catheterization laboratory using a pre-procedure survey: Opportunities for quality improvement. Cardiovascular Revascularization Medicine : Including Molecular Interventions. PMID 28529095 DOI: 10.1016/j.carrev.2017.05.004  0.06
2013 Povsic TJ, Sloane R, Green JB, Zhou J, Pieper CF, Pearson MP, Peterson ED, Cohen HJ, Morey MC. Depletion of circulating progenitor cells precedes overt diabetes: a substudy from the VA enhanced fitness trial. Journal of Diabetes and Its Complications. 27: 633-6. PMID 24055327 DOI: 10.1016/j.jdiacomp.2013.08.004  0.06
2020 Marquis-Gravel G, Huang Z, Zelenkofske SL, Lincoff AM, Mehran R, Steg PG, Bode C, Alexander JH, Povsic TJ. Interplay between PCI access site, anticoagulant agent, and bleeding: Insights from the REGULATE-PCI randomized trial. American Heart Journal. 223: 84-86. PMID 32199152 DOI: 10.1016/j.ahj.2020.02.013  0.06
2010 Lou J, Povsic TJ, Allen JD, Adams SD, Myles S, Starr AZ, Ortel TL, Becker RC. The effect of aspirin on endothelial progenitor cell biology: preliminary investigation of novel properties. Thrombosis Research. 126: e175-9. PMID 20659762 DOI: 10.1016/j.thromres.2009.11.017  0.058
2015 Patel MR, Conte MS, Cutlip DE, Dib N, Geraghty P, Gray W, Hiatt WR, Ho M, Ikeda K, Ikeno F, Jaff MR, Jones WS, Kawahara M, Lookstein RA, Mehran R, ... ... Povsic TJ, et al. Evaluation and treatment of patients with lower extremity peripheral artery disease: consensus definitions from Peripheral Academic Research Consortium (PARC). Journal of the American College of Cardiology. 65: 931-41. PMID 25744011 DOI: 10.1016/J.Jacc.2014.12.036  0.057
2016 Povsic TJ, Lawrence MG, Lincoff AM, Mehran R, Rusconi CP, Zelenkofske SL, Huang Z, Sailstad J, Armstrong PW, Steg PG, Bode C, Becker RC, Alexander JH, Adkinson NF, Levinson AI, et al. Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer. The Journal of Allergy and Clinical Immunology. PMID 27522158 DOI: 10.1016/J.Jaci.2016.04.058  0.057
2010 Povsic TJ, Zhou J, Adams SD, Bolognesi MP, Attarian DE, Peterson ED. Aging is not associated with bone marrow-resident progenitor cell depletion. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 65: 1042-50. PMID 20591876 DOI: 10.1093/gerona/glq110  0.057
2019 Ward R, Huang Z, Rockhold FW, Baumgartner I, Berger JS, Blomster JI, Fowkes FGR, Katona BG, Mahaffey KW, Norgren L, Vemulapalli S, Povsic TJ, Mehta R, Hiatt WR, Patel MR, et al. Major bleeding in patients with peripheral artery disease: Insights from the EUCLID trial. American Heart Journal. 220: 51-58. PMID 31783279 DOI: 10.1016/j.ahj.2019.11.007  0.057
2009 Povsic TJ, Adams SD, Zavodni KL, Kelly F, Melton LG, Rao SV, Najjar SS, Harrington RA, Peterson ED. Aldehyde dehydrogenase activity allows reliable EPC enumeration in stored peripheral blood samples. Journal of Thrombosis and Thrombolysis. 28: 259-65. PMID 19184616 DOI: 10.1007/s11239-009-0306-6  0.057
2013 Povsic TJ, Sloane R, Zhou J, Pieper CF, Pearson MP, Peterson ED, Green JB, Cohen HJ, Morey MC. Lower levels of circulating progenitor cells are associated with low physical function and performance in elderly men with impaired glucose tolerance: a pilot substudy from the VA Enhanced Fitness trial. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 1559-66. PMID 23682163 DOI: 10.1093/gerona/glt067  0.055
2016 Povsic T, Henry T, Jolicoeur M, Traverse J, Schatz R, Hunt A, Losordo D. TCT-821 Intramyocardial Autologous CD34+ Cell Therapy Reduces Mortality and Improves Exercise Capacity in Patients with Refractory Angina Journal of the American College of Cardiology. 68: B332-B333. DOI: 10.1016/j.jacc.2016.09.849  0.055
2018 Fanaroff AC, Clare R, Pieper K, Mahaffey K, Melloni C, Green J, Alexander J, Jones W, Harrison R, Mehta R, Povsic T, Moreira H, Al-Khatib S, Roe M, Kong D, et al. UNDETERMINED CAUSE OF DEATH: A POOLED ANALYSIS OF 9,307 DEATHS ACROSS 9 CARDIOVASCULAR TRIALS Journal of the American College of Cardiology. 71: A90. DOI: 10.1016/s0735-1097(18)30631-4  0.052
2016 Povsic TJ, Zeiher AM. IxCELL-DCM: rejuvenation for cardiac regenerative therapy? Lancet (London, England). 387: 2362-3. PMID 27059889 DOI: 10.1016/S0140-6736(16)30138-6  0.05
2014 Granger CB, Povsic TJ. Another biomarker for risk assessment in acute myocardial infarction? Journal of the American College of Cardiology. 64: 1708-10. PMID 25323259 DOI: 10.1016/j.jacc.2014.06.1200  0.05
2018 Povsic TJ. Approaching Regulatory Approval of Cardiovascular Regenerative Therapy. Circulation Research. 122: 552-554. PMID 29449363 DOI: 10.1161/CIRCRESAHA.117.312520  0.047
2011 Inrig JK, Van Buren P, Kim C, Vongpatanasin W, Povsic TJ, Toto RD. Intradialytic hypertension and its association with endothelial cell dysfunction. Clinical Journal of the American Society of Nephrology : Cjasn. 6: 2016-24. PMID 21757643 DOI: 10.2215/CJN.11351210  0.046
2009 Mills JS, N'diaye CS, Yow E, Urtz M, Povsic TJ, Greenfield JC, Phillips HR. Preliminary observations using optical coherence tomography to assess neointimal coverage of a metal stent in a porcine model Cardiovascular Revascularization Medicine. 10: 229-235. PMID 19815170 DOI: 10.1016/j.carrev.2008.11.003  0.044
2020 Povsic T, Sietsema W, Wang J, Takagi H, Kotynski C, Losordo D. Design of a confirmatory pivotal study with intramyocardial GCSF-mobilized autologous CD34 cells (CLBS14) for the treatment of an orphan-sized population with no-option refractory disabling angina Cytotherapy. 22: S64. DOI: 10.1016/j.jcyt.2020.03.096  0.043
1989 Povsic TJ, Dervan PB. Triple helix formation by oligonucleotides on DNA extended to the physiological pH range Journal of the American Chemical Society. 111: 3059-3061. DOI: 10.1021/Ja00190A047  0.043
1990 Povsic TJ, Dervan PB. Sequence-specific alkylation of double-helical DNA by oligonucleotide-directed triple-helix formation Journal of the American Chemical Society. 112: 9428-9430. DOI: 10.1021/Ja00181A075  0.042
1992 Povsic TJ, Strobel SA, Dervan PB. Sequence-specific double-strand alkylation and cleavage of DNA mediated by triple-helix formation Journal of the American Chemical Society. 114: 5934-5941. DOI: 10.1021/Ja00041A005  0.041
2017 Povsic TJ, Scott R, Mahaffey KW, Blaustein R, Edelberg JM, Lefkowitz MP, Solomon SD, Fox JC, Healy KE, Khakoo AY, Losordo DW, Malik FI, Monia BP, Montgomery RL, Riesmeyer J, et al. Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference. Cardiovascular Drugs and Therapy. PMID 28735360 DOI: 10.1007/S10557-017-6739-9  0.038
2015 Ganson NJ, Povsic TJ, Sullenger BA, Alexander JH, Zelenkofske SL, Sailstad JM, Rusconi CP, Hershfield MS. Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer. The Journal of Allergy and Clinical Immunology. PMID 26688515 DOI: 10.1016/J.Jaci.2015.10.034  0.037
2015 Povsic TJ, Sloane R, Pieper CF, Pearson MP, Peterson ED, Cohen HJ, Morey MC. Endothelial Progenitor Cell Levels Predict Future Physical Function: An Exploratory Analysis From the VA Enhanced Fitness Study. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26511012 DOI: 10.1093/gerona/glv180  0.035
2011 Mills JS, Stack-N'diaye C, Povsic T, Yow E, Urtz M, Greenfield J, Phillips H. OPTICAL COHERENCE TOMOGRAPHY ACCURATELY DETERMINES NEOINTIMAL COVERAGE AND STENT AREA OF BARE METAL AND DRUG-ELUTING CORONARY STENTS Journal of the American College of Cardiology. 57: E1743. DOI: 10.1016/S0735-1097(11)61743-9  0.034
2009 Povsic TJ, Zavodni KL, Vainorius E, Kherani JF, Goldschmidt-Clermont PJ, Peterson ED. Common endothelial progenitor cell assays identify discrete endothelial progenitor cell populations. American Heart Journal. 157: 335-44. PMID 19185643 DOI: 10.1016/J.Ahj.2008.10.010  0.031
2021 Goldsweig AM, Povsic TJ. Complex Percutaneous Coronary Intervention: Discrete Entity or Just Another Subgroup to Analyze? Circulation. Cardiovascular Interventions. CIRCINTERVENTIONS121. PMID 34130479 DOI: 10.1161/CIRCINTERVENTIONS.121.010891  0.029
2016 Fernandez CE, Yen RW, Perez SM, Bedell HW, Povsic TJ, Reichert WM, Truskey GA. Human vascular microphysiological system for in vitro drug screening Scientific Reports. 6. DOI: 10.1038/srep21579  0.024
2015 Patel MR, Conte MS, Cutlip DE, Dib N, Geraghty P, Gray W, Hiatt WR, Ho M, Ikeda K, Ikeno F, Jaff MR, Jones WS, Kawahara M, Lookstein RA, Mehran R, ... ... Povsic TJ, et al. Erratum: Evaluation and treatment of patients with lower extremity peripheral artery disease: Consensus definitions from Peripheral Academic Research Consortium (PARC) (Journal of the American College of Cardiology (2015) 65:(931-41)) Journal of the American College of Cardiology. 65: 2578-2579. DOI: 10.1016/J.Jacc.2015.04.049  0.023
2014 Al-Khatib SM, Allen LaPointe NM, Chatterjee R, Crowley MJ, Dupre ME, Kong DF, Lopes RD, Povsic TJ, Raju SS, Shah B, Kosinski AS, McBroom AJ, Sanders GD. Rate- and rhythm-control therapies in patients with atrial fibrillation: a systematic review. Annals of Internal Medicine. 160: 760-73. PMID 24887617 DOI: 10.7326/M13-1467  0.021
2019 Povsic TJ, Ohman EM, Gibson CM. Logistical Challenges Associated With Implementing Precision Medicine-Reply. Jama Cardiology. PMID 31664432 DOI: 10.1001/jamacardio.2019.4175  0.01
2018 Henry TD, Povsic TJ, Losordo DW. The (Translational) Road Less Traveled. Circulation Research. 122: 207-209. PMID 29348249 DOI: 10.1161/CIRCRESAHA.117.311987  0.01
2016 Povsic TJ, Losordo DW. Getting Back to Normal: Can Enhanced Regeneration Maintain Health? Circulation Research. 118: 1863-5. PMID 27283528 DOI: 10.1161/CIRCRESAHA.116.308936  0.01
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