Richard Thomas Layer - Publications

Affiliations: 
InVivo Therapeutics 
Area:
Neuropharmacology, Spinal Cord Injury

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Allen JW, Hofer K, McCumber D, Wagstaff JD, Layer RT, McCabe RT, Yaksh TL. An assessment of the antinociceptive efficacy of intrathecal and epidural contulakin-G in rats and dogs. Anesthesia and Analgesia. 104: 1505-13, table of co. PMID 17513650 DOI: 10.1213/01.ANE.0000219586.65112.FA  1
2006 Bulaj G, Zhang MM, Green BR, Fiedler B, Layer RT, Wei S, Nielsen JS, Low SJ, Klein BD, Wagstaff JD, Chicoine L, Harty TP, Terlau H, Yoshikami D, Olivera BM. Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity. Biochemistry. 45: 7404-14. PMID 16752929 DOI: 10.1021/bi060159+  1
2006 Layer RT, McIntosh JM. Conotoxins: Therapeutic potential and application Marine Drugs. 4: 119-142. DOI: 10.3390/md403119  1
2005 Lubbers NL, Campbell TJ, Polakowski JS, Bulaj G, Layer RT, Moore J, Gross GJ, Cox BF. Postischemic administration of CGX-1051, a peptide from cone snail venom, reduces infarct size in both rat and dog models of myocardial ischemia and reperfusion. Journal of Cardiovascular Pharmacology. 46: 141-6. PMID 16044024 DOI: 10.1097/01.fjc.0000167015.84715.27  1
2004 Layer RT, Wagstaff JD, White HS. Conantokins: peptide antagonists of NMDA receptors. Current Medicinal Chemistry. 11: 3073-84. PMID 15579001  1
2001 Layer RT. Saturation analysis of ligand binding using a centrifugation procedure. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit7.7. PMID 18428533 DOI: 10.1002/0471142301.ns0707s02  1
2000 Adams AC, Layer RT, McCabe RT, Keefe KA. Effects of conantokins on L-3,4-dihydroxyphenylalanine-induced behavior and immediate early gene expression. European Journal of Pharmacology. 404: 303-13. PMID 10996596 DOI: 10.1016/S0014-2999(00)00640-3  1
2000 McIntosh JM, Corpuz GO, Layer RT, Garrett JE, Wagstaff JD, Bulaj G, Vyazovkina A, Yoshikami D, Cruz LJ, Olivera BM. Isolation and characterization of a novel conus peptide with apparent antinociceptive activity. The Journal of Biological Chemistry. 275: 32391-7. PMID 10900201 DOI: 10.1074/jbc.M003619200  1
2000 Shen GS, Layer RT, McCabe RT. Conopeptides: From deadly venoms to novel therapeutics. Drug Discovery Today. 5: 98-106. PMID 10675883 DOI: 10.1016/S1359-6446(99)01454-3  1
1998 McCabe RT, Sofia RD, Layer RT, Leiner KA, Faull RL, Narang N, Wamsley JK. Felbamate increases [3H]glycine binding in rat brain and sections of human postmortem brain. The Journal of Pharmacology and Experimental Therapeutics. 286: 991-9. PMID 9694960  1
1997 Huang NY, Strakhova M, Layer RT, Skolnick P. Chronic antidepressant treatments increase cytochrome b mRNA levels in mouse cerebral cortex. Journal of Molecular Neuroscience : Mn. 9: 167-76. PMID 9481618 DOI: 10.1007/BF02800499  1
1997 Hill RA, Wallace LJ, Miller DD, Weinstein DM, Shams G, Tai H, Layer RT, Willins D, Uretsky NJ, Danthi SN. Structure--activity studies for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid receptors: acidic hydroxyphenylalanines. Journal of Medicinal Chemistry. 40: 3182-91. PMID 9379437 DOI: 10.1021/jm950028z  1
1996 Layer RT, Skolnick P, Bertha CM, Bandarage UK, Kuehne ME, Popik P. Structurally modified ibogaine analogs exhibit differing affinities for NMDA receptors. European Journal of Pharmacology. 309: 159-65. PMID 8874134 DOI: 10.1016/0014-2999(96)00304-4  1
1996 Skolnick P, Layer RT, Popik P, Nowak G, Paul IA, Trullas R. Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression. Pharmacopsychiatry. 29: 23-6. PMID 8852530 DOI: 10.1055/s-2007-979537  1
1995 Popik P, Lewin A, Berrang B, Nowak G, Layer R, Skolnick P. [3H]1-aminocyclopropanecarboxylic acid, a novel probe for strychnine- insensitive glycine receptors. European Journal of Pharmacology. 291: 221-7. PMID 8719405 DOI: 10.1016/0922-4106(95)90061-6  1
1995 Layer RT, Popik P, Olds T, Skolnick P. Antidepressant-like actions of the polyamine site NMDA antagonist, eliprodil (SL-82.0715). Pharmacology, Biochemistry, and Behavior. 52: 621-7. PMID 8545484 DOI: 10.1016/0091-3057(95)00155-P  1
1995 Popik P, Layer RT, Skolnick P. 100 years of ibogaine: neurochemical and pharmacological actions of a putative anti-addictive drug. Pharmacological Reviews. 47: 235-53. PMID 7568327  1
1995 Popik P, Layer RT, Fossom LH, Benveniste M, Geter-Douglass B, Witkin JM, Skolnick P. NMDA antagonist properties of the putative antiaddictive drug, ibogaine. The Journal of Pharmacology and Experimental Therapeutics. 275: 753-60. PMID 7473163  1
1994 Paul IA, Nowak G, Layer RT, Popik P, Skolnick P. Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments. The Journal of Pharmacology and Experimental Therapeutics. 269: 95-102. PMID 8169857  1
1994 Popik P, Layer RT, Skolnick P. The putative anti-addictive drug ibogaine is a competitive inhibitor of [3H]MK-801 binding to the NMDA receptor complex. Psychopharmacology. 114: 672-4. PMID 7531855 DOI: 10.1007/BF02245000  1
1993 Layer RT, Kaddis FG, Wallace LJ. The NMDA receptor antagonist MK-801 elicits conditioned place preference in rats. Pharmacology, Biochemistry, and Behavior. 44: 245-7. PMID 8430127 DOI: 10.1016/0091-3057(93)90306-E  1
1993 Layer RT, Uretsky NJ, Wallace LJ. Effects of the AMPA/kainate receptor antagonist DNQX in the nucleus accumbens on drug-induced conditioned place preference. Brain Research. 617: 267-73. PMID 8402155 DOI: 10.1016/0006-8993(93)91094-9  1
1993 Layer RT, Bland LR, Skolnick P. MK-801, but not drugs acting at strychnine-insensitive glycine receptors, attenuate methamphetamine nigrostriatal toxicity. Brain Research. 625: 38-44. PMID 8242398 DOI: 10.1016/0006-8993(93)90135-A  1
1993 Nowak G, Trullas R, Layer RT, Skolnick P, Paul IA. Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid. The Journal of Pharmacology and Experimental Therapeutics. 265: 1380-6. PMID 8099620  1
1993 Paul IA, Layer RT, Skolnick P, Nowak G. Adaptation of the NMDA receptor in rat cortex following chronic electroconvulsive shock or imipramine. European Journal of Pharmacology. 247: 305-11. PMID 7905831 DOI: 10.1016/0922-4106(93)90199-J  1
1992 Layer RT, Uretsky NJ, Wallace LJ. Effect of serotonergic agonists in the nucleus accumbens on d-amphetamine-stimulated locomotion. Life Sciences. 50: 813-20. PMID 1740965 DOI: 10.1016/0024-3205(92)90187-T  1
1992 Boldry RC, Layer RT, Wallace LJ, Uretsky NJ. Stimulation of locomotor activity by intra-accumbens AMPA is not inhibited by neonatal 6-hydroxydopamine-induced lesions. Neuroscience Letters. 138: 265-9. PMID 1376874 DOI: 10.1016/0304-3940(92)90930-6  1
1991 Layer RT, Uretsky NJ, Wallace LJ. Effects of morphine in the nucleus accumbens on stimulant-induced locomotion. Pharmacology, Biochemistry, and Behavior. 40: 21-6. PMID 1685784 DOI: 10.1016/0091-3057(91)90315-S  1
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