Matthew J. LaVoie - Publications

Affiliations: 
Brigham and Women's Hospital/Harvard Medical School, Boston, MA, United States 
Area:
Neurodegeneration

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Charan RA, LaVoie MJ. Pathologic and therapeutic implications for the cell biology of parkin. Molecular and Cellular Neurosciences. 66: 62-71. PMID 25697646 DOI: 10.1016/j.mcn.2015.02.008  1
2014 Schapansky J, Nardozzi JD, LaVoie MJ. The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease. Neuroscience. PMID 25284317 DOI: 10.1016/j.neuroscience.2014.09.049  1
2014 Ashrafi G, Schlehe JS, LaVoie MJ, Schwarz TL. Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. The Journal of Cell Biology. 206: 655-70. PMID 25154397 DOI: 10.1083/jcb.201401070  1
2014 Renella R, Schlehe JS, Selkoe DJ, Williams DA, LaVoie MJ. Genetic deletion of the GATA1-regulated protein α-synuclein reduces oxidative stress and nitric oxide synthase levels in mature erythrocytes. American Journal of Hematology. 89: 974-7. PMID 25043722 DOI: 10.1002/ajh.23796  1
2014 Charan RA, Johnson BN, Zaganelli S, Nardozzi JD, LaVoie MJ. Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin. Cell Death & Disease. 5: e1313. PMID 24991765 DOI: 10.1038/cddis.2014.278  1
2014 Schapansky J, Nardozzi JD, Felizia F, LaVoie MJ. Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy. Human Molecular Genetics. 23: 4201-14. PMID 24682598 DOI: 10.1093/hmg/ddu138  1
2013 Schlehe JS, Journel MS, Taylor KP, Amodeo KD, LaVoie MJ. The mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stress. Neurobiology of Disease. 58: 57-67. PMID 23702311 DOI: 10.1016/j.nbd.2013.05.007  1
2012 Johnson BN, Charan RA, LaVoie MJ. Recognizing the cooperative and independent mitochondrial functions of Parkin and PINK1. Cell Cycle (Georgetown, Tex.). 11: 2775-6. PMID 22801534 DOI: 10.4161/cc.21261  1
2012 Johnson BN, Berger AK, Cortese GP, Lavoie MJ. The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax. Proceedings of the National Academy of Sciences of the United States of America. 109: 6283-8. PMID 22460798 DOI: 10.1073/pnas.1113248109  1
2011 Wang X, Winter D, Ashrafi G, Schlehe J, Wong YL, Selkoe D, Rice S, Steen J, LaVoie MJ, Schwarz TL. PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell. 147: 893-906. PMID 22078885 DOI: 10.1016/j.cell.2011.10.018  1
2011 Bosco DA, LaVoie MJ, Petsko GA, Ringe D. Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis. Cold Spring Harbor Perspectives in Biology. 3: a007500. PMID 21844169 DOI: 10.1101/cshperspect.a007500  1
2011 Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, LaVoie MJ, Gris D, Park DS, Angel JB, Shen J, et al. Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 795-808. PMID 21552986 DOI: 10.1007/s00702-011-0653-2  1
2010 Berger Z, Smith KA, Lavoie MJ. Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation. Biochemistry. 49: 5511-23. PMID 20515039 DOI: 10.1021/bi100157u  1
2010 Chen AC, Guo LY, Ostaszewski BL, Selkoe DJ, LaVoie MJ. Aph-1 associates directly with full-length and C-terminal fragments of gamma-secretase substrates. The Journal of Biological Chemistry. 285: 11378-91. PMID 20145246 DOI: 10.1074/jbc.M109.088815  1
2009 Venderova K, Kabbach G, Abdel-Messih E, Zhang Y, Parks RJ, Imai Y, Gehrke S, Ngsee J, Lavoie MJ, Slack RS, Rao Y, Zhang Z, Lu B, Haque ME, Park DS. Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease. Human Molecular Genetics. 18: 4390-404. PMID 19692353 DOI: 10.1093/hmg/ddp394  1
2009 Berger AK, Cortese GP, Amodeo KD, Weihofen A, Letai A, LaVoie MJ. Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release. Human Molecular Genetics. 18: 4317-28. PMID 19679562 DOI: 10.1093/hmg/ddp384  1
2009 Rappley I, Myers DS, Milne SB, Ivanova PT, Lavoie MJ, Brown HA, Selkoe DJ. Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with alpha-synuclein genotype. Journal of Neurochemistry. 111: 15-25. PMID 19627450 DOI: 10.1111/j.1471-4159.2009.06290.x  1
2009 Rappley I, Gitler AD, Selvy PE, LaVoie MJ, Levy BD, Brown HA, Lindquist S, Selkoe DJ. Evidence that alpha-synuclein does not inhibit phospholipase D. Biochemistry. 48: 1077-83. PMID 19146388 DOI: 10.1021/bi801871h  1
2008 Piasecki BP, LaVoie M, Tam LW, Lefebvre PA, Silflow CD. The Uni2 phosphoprotein is a cell cycle regulated component of the basal body maturation pathway in Chlamydomonas reinhardtii. Molecular Biology of the Cell. 19: 262-73. PMID 17942595 DOI: 10.1091/mbc.E07-08-0798  1
2007 LaVoie MJ, Cortese GP, Ostaszewski BL, Schlossmacher MG. The effects of oxidative stress on parkin and other E3 ligases. Journal of Neurochemistry. 103: 2354-68. PMID 17883392 DOI: 10.1111/j.1471-4159.2007.04911.x  1
2005 Fraering PC, Ye W, LaVoie MJ, Ostaszewski BL, Selkoe DJ, Wolfe MS. gamma-Secretase substrate selectivity can be modulated directly via interaction with a nucleotide-binding site. The Journal of Biological Chemistry. 280: 41987-96. PMID 16236717 DOI: 10.1074/jbc.M501368200  1
2005 LaVoie MJ, Ostaszewski BL, Weihofen A, Schlossmacher MG, Selkoe DJ. Dopamine covalently modifies and functionally inactivates parkin. Nature Medicine. 11: 1214-21. PMID 16227987 DOI: 10.1038/nm1314  1
2004 Baulac S, LaVoie MJ, Strahle J, Schlossmacher MG, Xia W. Dimerization of Parkinson's disease-causing DJ-1 and formation of high molecular weight complexes in human brain. Molecular and Cellular Neurosciences. 27: 236-46. PMID 15519239 DOI: 10.1016/j.mcn.2004.06.014  1
2004 Fraering PC, Ye W, Strub JM, Dolios G, LaVoie MJ, Ostaszewski BL, van Dorsselaer A, Wang R, Selkoe DJ, Wolfe MS. Purification and characterization of the human gamma-secretase complex. Biochemistry. 43: 9774-89. PMID 15274632 DOI: 10.1021/bi0494976  1
2004 LaVoie MJ, Card JP, Hastings TG. Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity. Experimental Neurology. 187: 47-57. PMID 15081587 DOI: 10.1016/j.expneurol.2004.01.010  1
2004 Fraering PC, LaVoie MJ, Ye W, Ostaszewski BL, Kimberly WT, Selkoe DJ, Wolfe MS. Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex. Biochemistry. 43: 323-33. PMID 14717586 DOI: 10.1021/bi035748j  1
2003 Whitaker C, Eckman C, Almeida C, Feinstein D, Atwood C, Eckman E, Crutcher K, Hersh L, Leissring M, LaVoie M, Ertekin-Taner N, Shapiro P, Takahashi R, Yamin R, Mansourian S, et al. Live discussion: Amyloid-β degradation: The forgotten half of Alzheimer's disease Journal of Alzheimer's Disease. 5: 491-497. PMID 14765518  1
2003 Baulac S, LaVoie MJ, Kimberly WT, Strahle J, Wolfe MS, Selkoe DJ, Xia W. Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates. Neurobiology of Disease. 14: 194-204. PMID 14572442 DOI: 10.1016/S0969-9961(03)00123-2  1
2003 LaVoie MJ, Fraering PC, Ostaszewski BL, Ye W, Kimberly WT, Wolfe MS, Selkoe DJ. Assembly of the gamma-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin. The Journal of Biological Chemistry. 278: 37213-22. PMID 12857757 DOI: 10.1074/jbc.M303941200  1
2003 LaVoie MJ, Selkoe DJ. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments. The Journal of Biological Chemistry. 278: 34427-37. PMID 12826675 DOI: 10.1074/jbc.M302659200  1
2003 Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ. gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochemistry. 42: 6664-73. PMID 12779321 DOI: 10.1021/bi027375c  1
2003 Kimberly WT, LaVoie MJ, Ostaszewski BL, Ye W, Wolfe MS, Selkoe DJ. Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2. Proceedings of the National Academy of Sciences of the United States of America. 100: 6382-7. PMID 12740439 DOI: 10.1073/pnas.1037392100  1
2003 Kathir P, LaVoie M, Brazelton WJ, Haas NA, Lefebvre PA, Silflow CD. Molecular map of the Chlamydomonas reinhardtii nuclear genome. Eukaryotic Cell. 2: 362-79. PMID 12684385 DOI: 10.1128/EC.2.2.362-379.2003  1
2002 Kimberly WT, LaVoie MJ, Ostaszewski BL, Ye W, Wolfe MS, Selkoe DJ. Complex N-linked glycosylated nicastrin associates with active gamma-secretase and undergoes tight cellular regulation. The Journal of Biological Chemistry. 277: 35113-7. PMID 12130643 DOI: 10.1074/jbc.M204446200  1
2001 Silflow CD, Lavoie M, Tam LW, Tousey S, Sanders M, Wu WC, Borodovsky M, Lefebvre PA. The Vfl1 protein in Chlamydomonas localizes in a rotationally asymmetric pattern at the distal ends of the basal bodies Journal of Cell Biology. 153: 63-74. PMID 11285274 DOI: 10.1083/jcb.153.1.63  1
1999 Silflow CD, Liu B, LaVoie M, Richardson EA, Palevitz BA. γ-tubulin in Chlamydomonas: Characterization of the gene and localization of the gene product in cells Cell Motility and the Cytoskeleton. 42: 285-297. PMID 10223635 DOI: 10.1002/(SICI)1097-0169(1999)42:4<285::AID-CM3>3.0.CO;2-Z  1
1999 LaVoie MJ, Hastings TG. Dopamine quinone formation and protein modification associated with the striatal neurotoxicity of methamphetamine: evidence against a role for extracellular dopamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1484-91. PMID 9952424  1
1995 Vassilev A, Kimble M, Silflow CD, LaVoie M, Kuriyama R. Identification of intrinsic dimer and overexpressed monomeric forms of γ-tubulin in Sf9 cells infected with baculovirus containing the Chlamydomonas γ-tubulin sequence Journal of Cell Science. 108: 1083-1092. PMID 7622595  1
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