| Year |
Citation |
Score |
| 2024 |
Sasmita AO, Depp C, Nazarenko T, Sun T, Siems SB, Ong EC, Nkeh YB, Böhler C, Yu X, Bues B, Evangelista L, Mao S, Morgado B, Wu Z, Ruhwedel T, ... ... Eggert S, et al. Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice. Nature Neuroscience. PMID 39103558 DOI: 10.1038/s41593-024-01730-3 |
0.467 |
|
| 2023 |
Schilling S, August A, Meleux M, Conradt C, Tremmel LM, Teigler S, Adam V, Müller UC, Koo EH, Kins S, Eggert S. APP family member dimeric complexes are formed predominantly in synaptic compartments. Cell & Bioscience. 13: 141. PMID 37533067 DOI: 10.1186/s13578-023-01092-6 |
0.657 |
|
| 2023 |
Schilling S, Pradhan A, Heesch A, Helbig A, Blennow K, Koch C, Bertgen L, Koo EH, Brinkmalm G, Zetterberg H, Kins S, Eggert S. Differential effects of familial Alzheimer's disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity. Acta Neuropathologica Communications. 11: 87. PMID 37259128 DOI: 10.1186/s40478-023-01577-y |
0.642 |
|
| 2022 |
Busch L, Eggert S, Endres K, Bufe B. The Hidden Role of Non-Canonical Amyloid β Isoforms in Alzheimer's Disease. Cells. 11. PMID 36359817 DOI: 10.3390/cells11213421 |
0.429 |
|
| 2021 |
Eggert S, Kins S, Endres K, Brigadski T. Brothers in arms: proBDNF/BDNF and sAPPα/Aβ-signaling and their common interplay with ADAM10, TrkB, p75NTR, sortilin, and sorLA in the progression of Alzheimer's disease. Biological Chemistry. PMID 34619027 DOI: 10.1515/hsz-2021-0330 |
0.345 |
|
| 2020 |
Eggert S, Gruebl T, Rajender R, Rupp C, Sander B, Heesch A, Zimmermann M, Hoepfner S, Zentgraf H, Kins S. The Rab5 activator RME-6 is required for amyloid precursor protein endocytosis depending on the YTSI motif. Cellular and Molecular Life Sciences : Cmls. PMID 32065241 DOI: 10.1007/s00018-020-03467-1 |
0.499 |
|
| 2017 |
Eggert S, Thomas C, Kins S, Hermey G. Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin. Molecular Neurobiology. PMID 29079999 DOI: 10.1007/s12035-017-0806-x |
0.485 |
|
| 2017 |
Eggert S, Gonzalez AC, Thomas C, Schilling S, Schwarz SM, Tischer C, Adam V, Strecker P, Schmidt V, Willnow TE, Hermey G, Pietrzik CU, Koo EH, Kins S. Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA. Cellular and Molecular Life Sciences : Cmls. PMID 28799085 DOI: 10.1007/S00018-017-2625-7 |
0.758 |
|
| 2017 |
Herr UM, Strecker P, Storck SE, Thomas C, Rabiej V, Junker A, Schilling S, Schmidt N, Dowds CM, Eggert S, Pietrzik CU, Kins S. LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State. Frontiers in Molecular Neuroscience. 10: 118. PMID 28496400 DOI: 10.3389/fnmol.2017.00118 |
0.649 |
|
| 2017 |
Schilling S, Mehr A, Ludewig S, Stephan J, Zimmermann M, August A, Strecker P, Korte M, Koo EH, Müller U, Kins S, Eggert S. APLP1 is a synaptic cell adhesion molecule, supporting maintenance of dendritic spines and basal synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28450540 DOI: 10.1523/Jneurosci.1875-16.2017 |
0.662 |
|
| 2014 |
Stahl R, Schilling S, Soba P, Rupp C, Hartmann T, Wagner K, Merdes G, Eggert S, Kins S. Shedding of APP limits its synaptogenic activity and cell adhesion properties. Frontiers in Cellular Neuroscience. 8: 410. PMID 25520622 DOI: 10.3389/Fncel.2014.00410 |
0.754 |
|
| 2014 |
Baumkötter F, Schmidt N, Vargas C, Schilling S, Weber R, Wagner K, Fiedler S, Klug W, Radzimanowski J, Nickolaus S, Keller S, Eggert S, Wild K, Kins S. Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11159-72. PMID 25122912 DOI: 10.1523/JNEUROSCI.0180-14.2014 |
0.334 |
|
| 2013 |
Nagahara AH, Mateling M, Kovacs I, Wang L, Eggert S, Rockenstein E, Koo EH, Masliah E, Tuszynski MH. Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15596-602. PMID 24068826 DOI: 10.1523/Jneurosci.5195-12.2013 |
0.584 |
|
| 2013 |
Thyrock A, Ossendorf E, Stehling M, Kail M, Kurtz T, Pohlentz G, Waschbüsch D, Eggert S, Formstecher E, Müthing J, Dreisewerd K, Kins S, Goud B, Barnekow A. A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6. Plos One. 8: e64149. PMID 23737971 DOI: 10.1371/Journal.Pone.0064149 |
0.406 |
|
| 2012 |
Tyan SH, Shih AY, Walsh JJ, Maruyama H, Sarsoza F, Ku L, Eggert S, Hof PR, Koo EH, Dickstein DL. Amyloid precursor protein (APP) regulates synaptic structure and function. Molecular and Cellular Neurosciences. 51: 43-52. PMID 22884903 DOI: 10.1016/J.Mcn.2012.07.009 |
0.688 |
|
| 2012 |
Midthune B, Tyan SH, Walsh JJ, Sarsoza F, Eggert S, Hof PR, Dickstein DL, Koo EH. Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. Molecular and Cellular Neurosciences. 49: 448-55. PMID 22353605 DOI: 10.1016/J.Mcn.2012.02.001 |
0.755 |
|
| 2012 |
Isbert S, Wagner K, Eggert S, Schweitzer A, Multhaup G, Weggen S, Kins S, Pietrzik CU. APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms. Cellular and Molecular Life Sciences : Cmls. 69: 1353-75. PMID 22105709 DOI: 10.1007/S00018-011-0882-4 |
0.738 |
|
| 2012 |
Baumkötter F, Wagner K, Eggert S, Wild K, Kins S. Structural aspects and physiological consequences of APP/APLP trans-dimerization. Experimental Brain Research. 217: 389-95. PMID 21952790 DOI: 10.1007/s00221-011-2878-6 |
0.524 |
|
| 2011 |
Kukar TL, Ladd TB, Robertson P, Pintchovski SA, Moore B, Bann MA, Ren Z, Jansen-West K, Malphrus K, Eggert S, Maruyama H, Cottrell BA, Das P, Basi GS, Koo EH, et al. Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane region. The Journal of Biological Chemistry. 286: 39804-12. PMID 21868378 DOI: 10.1074/Jbc.M111.274696 |
0.668 |
|
| 2010 |
Walsh JJ, Tyan S, Midthune B, Yu-Jung Shih A, Eggert S, Hof PR, Koo E, Dickstein DL. P1-135: Comparison of neuronal morphology in pyramidal neurons of the CA1, dentate gyrus, and prefrontal cortex of APP knockout and APLP2 knockout mice Alzheimer's & Dementia. 6: S213-S213. DOI: 10.1016/J.Jalz.2010.05.684 |
0.686 |
|
| 2010 |
Kukar T, Ladd T, Robertson P, Moore B, Jansen-West K, Eggert S, Koo E, Golde T. O2-03-01: Insight into the mechanism of gamma-secretase cleavage: Juxtamembrane amino acids are key to the length of secreted amyloid beta peptide Alzheimer's & Dementia. 6: S100-S100. DOI: 10.1016/J.Jalz.2010.05.314 |
0.565 |
|
| 2010 |
Nagahara AH, Mateling M, Eggert S, Blesch A, Rockenstein E, Koo EH, Masliah E, Tuszynski MH. P3-323: Early BDNF gene delivery into entorhinal cortex in APP transgenic mice ameliorates cells loss and preserves context-dependent fear conditioning Alzheimer's & Dementia. 6: S547-S547. DOI: 10.1016/J.Jalz.2010.05.1824 |
0.506 |
|
| 2010 |
Tyan S, Midthune B, Eggert S, Dickstein DL, Koo EH. P2-328: Role of amyloid precursor proteins and beta-amyloid-induced synaptic dysfunction Alzheimer's & Dementia. 6: S409-S409. DOI: 10.1016/J.Jalz.2010.05.1379 |
0.74 |
|
| 2009 |
Eggert S, Midthune B, Cottrell B, Koo EH. Induced dimerization of the amyloid precursor protein leads to decreased amyloid-beta protein production. The Journal of Biological Chemistry. 284: 28943-52. PMID 19596858 DOI: 10.1074/Jbc.M109.038646 |
0.758 |
|
| 2006 |
Kuan YH, Gruebl T, Soba P, Eggert S, Nesic I, Back S, Kirsch J, Beyreuther K, Kins S. PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2. The Journal of Biological Chemistry. 281: 40114-23. PMID 17050537 DOI: 10.1074/Jbc.M605407200 |
0.783 |
|
| 2005 |
Soba P, Eggert S, Wagner K, Zentgraf H, Siehl K, Kreger S, Löwer A, Langer A, Merdes G, Paro R, Masters CL, Müller U, Kins S, Beyreuther K. Homo- and heterodimerization of APP family members promotes intercellular adhesion. The Embo Journal. 24: 3624-34. PMID 16193067 DOI: 10.1038/Sj.Emboj.7600824 |
0.761 |
|
| 2004 |
Eggert S, Paliga K, Soba P, Evin G, Masters CL, Weidemann A, Beyreuther K. The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation. The Journal of Biological Chemistry. 279: 18146-56. PMID 14970212 DOI: 10.1074/Jbc.M311601200 |
0.777 |
|
| 2003 |
Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ. gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochemistry. 42: 6664-73. PMID 12779321 DOI: 10.1021/Bi027375C |
0.631 |
|
| 2002 |
Weidemann A, Eggert S, Reinhard FB, Vogel M, Paliga K, Baier G, Masters CL, Beyreuther K, Evin G. A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing. Biochemistry. 41: 2825-35. PMID 11851430 DOI: 10.1021/Bi015794O |
0.596 |
|
| 2000 |
Reinhard FB, Eggert S, Kreger S, Soba PA, Weidemann A. Analysis of the role of charge residues in the transmembrane domains of presenilin-2 Neurobiology of Aging. 21: 112. DOI: 10.1016/S0197-4580(00)82304-0 |
0.609 |
|
| Show low-probability matches. |