| Year |
Citation |
Score |
| 2023 |
Faleschini T, Syafni N, Schulte HL, Garifulina A, Hering S, Espindola LS, Hamburger M. A neolignan from Connarus tuberosus as an allosteric GABA receptor modulator at the neurosteroid binding site. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 161: 114498. PMID 36906973 DOI: 10.1016/j.biopha.2023.114498 |
0.505 |
|
| 2022 |
Heider J, Kilian J, Garifulina A, Hering S, Langer T, Seidel T. : A Versatile Workflow for the Generation of Receptor-based Pharmacophore Models for Virtual Screening. Journal of Chemical Information and Modeling. 63: 101-110. PMID 36526584 DOI: 10.1021/acs.jcim.2c00814 |
0.314 |
|
| 2022 |
Garifulina A, Friesacher T, Stadler M, Zangerl-Plessl EM, Ernst M, Stary-Weinzinger A, Willam A, Hering S. β subunits of GABA receptors form proton-gated chloride channels: Insights into the molecular basis. Communications Biology. 5: 784. PMID 35922471 DOI: 10.1038/s42003-022-03720-2 |
0.308 |
|
| 2022 |
Syafni N, Faleschini MT, Garifulina A, Danton O, Gupta MP, Hering S, Hamburger M. Clerodane Diterpenes from as Allosteric GABA Receptor Modulators. Journal of Natural Products. PMID 35475609 DOI: 10.1021/acs.jnatprod.1c00840 |
0.547 |
|
| 2019 |
Syafni N, Moradi-Afrapoli F, Danton O, Wilhelm A, Stadler M, Hering S, Potterat O, Hamburger M. HPLC-Based Activity Profiling for GABAA Receptor Modulators in Murraya exotica Natural Product Communications. 14: 1934578X1901400. DOI: 10.1177/1934578X1901400112 |
0.546 |
|
| 2018 |
Stadler M, Monticelli S, Seidel T, Luger D, Salzer I, Boehm S, Holzer W, Schwarzer C, Urban E, Khom S, Langer T, Pace V, Hering S. Design, synthesis and pharmacological evaluation of novel β2/3 subunit-selective γ-Aminobutyric Acid Type A (GABAA) receptor modulators. Journal of Medicinal Chemistry. PMID 30289721 DOI: 10.1021/acs.jmedchem.8b00859 |
0.762 |
|
| 2017 |
Moradi-Afrapoli F, van der Merwe H, De Mieri M, Wilhelm A, Stadler M, Zietsman PC, Hering S, Swart K, Hamburger M. HPLC-Based Activity Profiling for GABAA Receptor Modulators in Searsia pyroides Using a Larval Zebrafish Locomotor Assay. Planta Medica. PMID 28511229 DOI: 10.1055/s-0043-110768 |
0.374 |
|
| 2016 |
Khom S, Hintersteiner J, Luger D, Haider M, Pototschnig G, Mihovilovic MD, Schwarzer C, Hering S. Analysis of β-Subunit-dependent GABAA Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives. The Journal of Pharmacology and Experimental Therapeutics. 357: 580-90. PMID 27190170 DOI: 10.1124/jpet.116.232983 |
0.691 |
|
| 2015 |
Bernaskova M, Schoeffmann A, Schuehly W, Hufner A, Baburin I, Hering S. Nitrogenated honokiol derivatives allosterically modulate GABAA receptors and act as strong partial agonists. Bioorganic & Medicinal Chemistry. 23: 6757-62. PMID 26410663 DOI: 10.1016/j.bmc.2015.08.034 |
0.374 |
|
| 2015 |
Luger D, Poli G, Wieder M, Stadler M, Ke S, Ernst M, Hohaus A, Linder T, Seidel T, Langer T, Khom S, Hering S. Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis. British Journal of Pharmacology. PMID 26375408 DOI: 10.1111/bph.13329 |
0.699 |
|
| 2015 |
Wimmer L, Schönbauer D, Pakfeifer P, Schöffmann A, Khom S, Hering S, Mihovilovic MD. Developing piperine towards TRPV1 and GABAA receptor ligands--synthesis of piperine analogs via Heck-coupling of conjugated dienes. Organic & Biomolecular Chemistry. 13: 990-4. PMID 25438036 DOI: 10.1039/c4ob02242d |
0.711 |
|
| 2014 |
Rueda DC, Raith M, De Mieri M, Schöffmann A, Hering S, Hamburger M. Identification of dehydroabietc acid from Boswellia thurifera resin as a positive GABAA receptor modulator. Fitoterapia. 99: 28-34. PMID 25200370 DOI: 10.1016/j.fitote.2014.09.002 |
0.491 |
|
| 2014 |
Strommer B, Khom S, Kastenberger I, Cicek SS, Stuppner H, Schwarzer C, Hering S. A cycloartane glycoside derived from Actaea racemosa L. modulates GABAA receptors and induces pronounced sedation in mice. The Journal of Pharmacology and Experimental Therapeutics. 351: 234-42. PMID 25161170 DOI: 10.1124/jpet.114.218024 |
0.757 |
|
| 2014 |
Schöffmann A, Wimmer L, Goldmann D, Khom S, Hintersteiner J, Baburin I, Schwarz T, Hintersteininger M, Pakfeifer P, Oufir M, Hamburger M, Erker T, Ecker GF, Mihovilovic MD, Hering S. Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives. Journal of Medicinal Chemistry. 57: 5602-19. PMID 24905252 DOI: 10.1021/Jm5002277 |
0.68 |
|
| 2014 |
Hintersteiner J, Haider M, Luger D, Schwarzer C, Reznicek G, Jäger W, Khom S, Mihovilovic MD, Hering S. Esters of valerenic acid as potential prodrugs. European Journal of Pharmacology. 735: 123-31. PMID 24680924 DOI: 10.1016/j.ejphar.2014.03.019 |
0.763 |
|
| 2014 |
Rueda DC, De Mieri M, Hering S, Hamburger M. HPLC-based activity profiling for GABAA receptor modulators in Adenocarpus cincinnatus. Journal of Natural Products. 77: 640-9. PMID 24571311 DOI: 10.1021/np500016z |
0.47 |
|
| 2014 |
Rueda DC, Schöffmann A, De Mieri M, Raith M, Jähne EA, Hering S, Hamburger M. Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators. Bioorganic & Medicinal Chemistry. 22: 1276-84. PMID 24462176 DOI: 10.1016/j.bmc.2014.01.008 |
0.568 |
|
| 2013 |
Schramm A, Ebrahimi SN, Raith M, Zaugg J, Rueda DC, Hering S, Hamburger M. Phytochemical profiling of Curcuma kwangsiensis rhizome extract, and identification of labdane diterpenoids as positive GABAA receptor modulators. Phytochemistry. 96: 318-29. PMID 24011802 DOI: 10.1016/j.phytochem.2013.08.004 |
0.408 |
|
| 2013 |
Khom S, Strommer B, Schöffmann A, Hintersteiner J, Baburin I, Erker T, Schwarz T, Schwarzer C, Zaugg J, Hamburger M, Hering S. GABAA receptor modulation by piperine and a non-TRPV1 activating derivative. Biochemical Pharmacology. 85: 1827-36. PMID 23623790 DOI: 10.1016/J.Bcp.2013.04.017 |
0.8 |
|
| 2013 |
Rueda D, de Mieri M, Hering S, Hamburger M. Isoflavonoid derivatives from Adenocarpus cincinnatus as positive GABAA receptor modulators Planta Medica. 79. DOI: 10.1055/S-0033-1352179 |
0.389 |
|
| 2013 |
Rueda D, Schöffmann A, de Mieri M, Raith M, Jähne E, Hering S, Hamburger M. Identification of dihydrostilbenes as a new scaffold for GABAA receptor modulators in Pholidota chinensis stems and roots Planta Medica. 79. DOI: 10.1055/s-0033-1351811 |
0.3 |
|
| 2012 |
Kim HJ, Baburin I, Zaugg J, Ebrahimi SN, Hering S, Hamburger M. HPLC-based activity profiling--discovery of sanggenons as GABAA receptor modulators in the traditional Chinese drug Sang bai pi (Morus alba root bark). Planta Medica. 78: 440-7. PMID 22294264 DOI: 10.1055/s-0031-1298229 |
0.575 |
|
| 2012 |
Rueda DC, Zaugg J, Quitschau M, Reich E, Hering S, Hamburger M. Discovery of GABA(A) receptor modulator aristolactone in a commercial sample of the Chinese herbal drug "Chaihu" (Bupleurum chinense roots) unravels adulteration by nephrotoxic Aristolochia manshuriensis roots. Planta Medica. 78: 207-10. PMID 22271081 DOI: 10.1055/s-0031-1298171 |
0.33 |
|
| 2012 |
Singhuber J, Baburin I, Khom S, Zehl M, Urban E, Hering S, Kopp B. GABA(A) receptor modulators from the Chinese herbal drug Junci Medulla--the pith of Juncus effusus. Planta Medica. 78: 455-8. PMID 22271080 DOI: 10.1055/s-0031-1298174 |
0.786 |
|
| 2012 |
Singhuber J, Baburin I, Kählig H, Urban E, Kopp B, Hering S. GABA(A) receptor modulators from Chinese herbal medicines traditionally applied against insomnia and anxiety. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 19: 334-40. PMID 22118921 DOI: 10.1016/j.phymed.2011.10.009 |
0.547 |
|
| 2011 |
Zaugg J, Ebrahimi SN, Smiesko M, Baburin I, Hering S, Hamburger M. Identification of GABA A receptor modulators in Kadsura longipedunculata and assignment of absolute configurations by quantum-chemical ECD calculations. Phytochemistry. 72: 2385-95. PMID 21889177 DOI: 10.1016/j.phytochem.2011.08.014 |
0.544 |
|
| 2011 |
Zaugg J, Khom S, Eigenmann D, Baburin I, Hamburger M, Hering S. Identification and characterization of GABA(A) receptor modulatory diterpenes from Biota orientalis that decrease locomotor activity in mice. Journal of Natural Products. 74: 1764-72. PMID 21793559 DOI: 10.1021/np200317p |
0.75 |
|
| 2011 |
Singhuber J, Baburin I, Ecker GF, Kopp B, Hering S. Insights into structure-activity relationship of GABAA receptor modulating coumarins and furanocoumarins. European Journal of Pharmacology. 668: 57-64. PMID 21749864 DOI: 10.1016/J.Ejphar.2011.06.034 |
0.415 |
|
| 2011 |
Taferner B, Schuehly W, Huefner A, Baburin I, Wiesner K, Ecker GF, Hering S. Modulation of GABAA-receptors by honokiol and derivatives: subtype selectivity and structure-activity relationship. Journal of Medicinal Chemistry. 54: 5349-61. PMID 21699169 DOI: 10.1021/Jm200186N |
0.366 |
|
| 2011 |
Zaugg J, Eickmeier E, Ebrahimi SN, Baburin I, Hering S, Hamburger M. Positive GABA(A) receptor modulators from Acorus calamus and structural analysis of (+)-dioxosarcoguaiacol by 1D and 2D NMR and molecular modeling. Journal of Natural Products. 74: 1437-43. PMID 21563811 DOI: 10.1021/np200181d |
0.393 |
|
| 2011 |
Yang X, Baburin I, Plitzko I, Hering S, Hamburger M. HPLC-based activity profiling for GABAA receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root). Molecular Diversity. 15: 361-72. PMID 21207144 DOI: 10.1007/s11030-010-9297-7 |
0.572 |
|
| 2011 |
Zaugg J, Eickmeier E, Rueda DC, Hering S, Hamburger M. HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes. Fitoterapia. 82: 434-40. PMID 21147202 DOI: 10.1016/j.fitote.2010.12.001 |
0.586 |
|
| 2010 |
Cicek SS, Khom S, Taferner B, Hering S, Stuppner H. Bioactivity-guided isolation of GABA(A) receptor modulating constituents from the rhizomes of Actaea racemosa. Journal of Natural Products. 73: 2024-8. PMID 21082802 DOI: 10.1021/np100479w |
0.771 |
|
| 2010 |
Khom S, Strommer B, Ramharter J, Schwarz T, Schwarzer C, Erker T, Ecker GF, Mulzer J, Hering S. Valerenic acid derivatives as novel subunit-selective GABAA receptor ligands - in vitro and in vivo characterization. British Journal of Pharmacology. 161: 65-78. PMID 20718740 DOI: 10.1111/J.1476-5381.2010.00865.X |
0.793 |
|
| 2010 |
Li Y, Plitzko I, Zaugg J, Hering S, Hamburger M. HPLC-based activity profiling for GABA(A) receptor modulators: a new dihydroisocoumarin from Haloxylon scoparium. Journal of Natural Products. 73: 768-70. PMID 20210326 DOI: 10.1021/np900803w |
0.554 |
|
| 2010 |
Zaugg J, Baburin I, Strommer B, Kim H, Hering S, Hamburger M. HPLC-Based Activity Profiling: Discovery of Piperine as a Positive GABAA Receptor Modulator Targeting a Benzodiazepine-Independent Binding Site Journal of Natural Products. 73: 185-191. PMID 20085307 DOI: 10.1021/Np900656G |
0.467 |
|
| 2010 |
Rueda D, Zaugg J, Hering S, Hamburger M. Identification of γ-aminobutyric acid type A (GABAA) receptor modulators: HPLC-based activity profiling of Asarum heterotropoides Planta Medica. 76. DOI: 10.1055/S-0030-1264920 |
0.449 |
|
| 2009 |
Baburin I, Khom S, Timin E, Hohaus A, Sieghart W, Hering S. Benzodiazepines modulate GABAA receptors by reducing a gamma-subunit-mediated inhibition of GABA sensitivity Bmc Pharmacology. 9: A23. DOI: 10.1186/1471-2210-9-S2-A23 |
0.768 |
|
| 2009 |
Zaugg J, Baburin I, Hering S, Hamburger M. Identifying GABAA receptor ligands in black pepper by activity profiling, LC-TOFMS, and offline microprobe NMR Planta Medica. 75. DOI: 10.1055/S-0029-1234276 |
0.317 |
|
| 2008 |
Baburin I, Khom S, Timin E, Hohaus A, Sieghart W, Hering S. Estimating the efficiency of benzodiazepines on GABA(A) receptors comprising gamma1 or gamma2 subunits. British Journal of Pharmacology. 155: 424-33. PMID 18604239 DOI: 10.1038/bjp.2008.271 |
0.768 |
|
| 2008 |
Kim HJ, Baburin I, Khom S, Hering S, Hamburger M. HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes. Planta Medica. 74: 521-6. PMID 18543148 DOI: 10.1055/s-2008-1074491 |
0.76 |
|
| 2008 |
Trauner G, Khom S, Baburin I, Benedek B, Hering S, Kopp B. Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid. Planta Medica. 74: 19-24. PMID 18095218 DOI: 10.1055/s-2007-993761 |
0.733 |
|
| 2007 |
Khom S, Baburin I, Timin E, Hohaus A, Trauner G, Kopp B, Hering S. Valerenic acid potentiates and inhibits GABA(A) receptors: molecular mechanism and subunit specificity. Neuropharmacology. 53: 178-87. PMID 17585957 DOI: 10.1016/j.neuropharm.2007.04.018 |
0.754 |
|
| 2007 |
Kim H, Khom S, Baburin I, Hering S, Hamburger M. HPLC-based activity profiling of plant and fungal extracts for GABAA receptor ligands using a functional assay with Xenopus oocytes Planta Medica. 73. DOI: 10.1055/s-2007-986720 |
0.679 |
|
| 2006 |
Khom S, Baburin I, Timin EN, Hohaus A, Sieghart W, Hering S. Pharmacological properties of GABAA receptors containing gamma1 subunits. Molecular Pharmacology. 69: 640-9. PMID 16272224 DOI: 10.1124/mol.105.017236 |
0.749 |
|
| 2006 |
Brattström A, Baburin I, Khom S, Hering S, Koetter U. Valerian extract modulates the GABAA-action on its receptors Planta Medica. 72. DOI: 10.1055/S-2006-950024 |
0.72 |
|
| 2006 |
Trauner G, Khom S, Benedek B, Hering S, Kopp B. Identification of GABAA-modulators obtained from Valeriana officinalis L Planta Medica. 72. DOI: 10.1055/S-2006-949848 |
0.628 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2019 |
Hamulić D, Stadler M, Hering S, Padrón JM, Bassett R, Rivas F, Loza-Mejía MA, Dea-Ayuela MA, González-Cardenete MA. Synthesis and Biological Studies of (+)-Liquiditerpenoic Acid A (Abietopinoic Acid) and Representative Analogues: SAR Studies. Journal of Natural Products. PMID 30840453 DOI: 10.1021/Acs.Jnatprod.8B00884 |
0.256 |
|
| 2021 |
González-Cardenete MA, Rivas F, Basset R, Stadler M, Hering S, Padrón JM, Zaragozá RJ, Dea-Ayuela MA. Biological Profiling of Semisynthetic C19-Functionalized Ferruginol and Sugiol Analogues. Antibiotics (Basel, Switzerland). 10. PMID 33673350 DOI: 10.3390/antibiotics10020184 |
0.249 |
|
| 2010 |
Singhuber J, Baburin I, Zehl M, Hering S, Kopp B. Natural coumarins and furanocoumarins as positive gabaergic modulators Planta Medica. 76. DOI: 10.1055/S-0030-1264209 |
0.232 |
|
| 1997 |
Sinnegger MJ, Wang Z, Grabner M, Hering S, Striessnig J, Glossmann H, Mitterdorfer J. Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel alpha1A subunit. Role of L-type Met1188. The Journal of Biological Chemistry. 272: 27686-93. PMID 9346909 DOI: 10.1074/Jbc.272.44.27686 |
0.223 |
|
| 2015 |
De Mieri M, Du K, Neuburger M, Saxena P, Zietsman PC, Hering S, van der Westhuizen JH, Hamburger M. hERG Channel Inhibitory Daphnane Diterpenoid Orthoesters and Polycephalones A and B with Unprecedented Skeletons from Gnidia polycephala. Journal of Natural Products. PMID 26091146 DOI: 10.1021/acs.jnatprod.5b00344 |
0.219 |
|
| 1996 |
Mitterdorfer J, Wang Z, Sinnegger MJ, Hering S, Striessnig J, Grabner M, Glossmann H. Two amino acid residues in the IIIS5 segment of L-type calcium channels differentially contribute to 1,4-dihydropyridine sensitivity. The Journal of Biological Chemistry. 271: 30330-5. PMID 8939992 DOI: 10.1074/Jbc.271.48.30330 |
0.215 |
|
| 1989 |
Hering S, Kleppisch T, Timin EN, Bodewei R. Characterization of the calcium channel state transitions induced by the enantiomers of the 1,4-dihydropyridine Sandoz 202 791 in neonatal rat heart cells. A nonmodulated receptor model. Pflugers Archiv : European Journal of Physiology. 414: 690-700. PMID 2554248 DOI: 10.1007/BF00582137 |
0.215 |
|
| 1997 |
Degtiar VE, Aczél S, Döring F, Timin EN, Berjukow S, Kimball D, Mitterdorfer J, Hering S. Calcium channel block by (-)devapamil is affected by the sequence environment and composition of the phenylalkylamine receptor site. Biophysical Journal. 73: 157-67. PMID 9199780 DOI: 10.1016/S0006-3495(97)78056-1 |
0.208 |
|
| 2011 |
Schramm A, Baburin I, Hering S, Hamburger M. HERG channel inhibitors in extracts of Coptidis rhizoma. Planta Medica. 77: 692-7. PMID 21412693 DOI: 10.1055/s-0030-1270920 |
0.204 |
|
| 1998 |
Kraus RL, Hering S, Grabner M, Ostler D, Striessnig J. Molecular mechanism of diltiazem interaction with L-type Ca2+ channels. The Journal of Biological Chemistry. 273: 27205-12. PMID 9765241 DOI: 10.1074/Jbc.273.42.27205 |
0.203 |
|
| 2015 |
Du K, De Mieri M, Saxena P, Phungula KV, Wilhelm A, Hrubaru MM, van Rensburg E, Zietsman PC, Hering S, van der Westhuizen JH, Hamburger M. HPLC-Based Activity Profiling for hERG Channel Inhibitors in the South African Medicinal Plant Galenia africana. Planta Medica. PMID 25922911 DOI: 10.1055/s-0035-1545929 |
0.201 |
|
| 1999 |
Berjukow S, Gapp F, Aczél S, Sinnegger MJ, Mitterdorfer J, Glossmann H, Hering S. Sequence differences between alpha1C and alpha1S Ca2+ channel subunits reveal structural determinants of a guarded and modulated benzothiazepine receptor. The Journal of Biological Chemistry. 274: 6154-60. PMID 10037699 DOI: 10.1074/Jbc.274.10.6154 |
0.199 |
|
| 1993 |
Hering S, Hughes AD, Timin EN, Bolton TB. Modulation of calcium channels in arterial smooth muscle cells by dihydropyridine enantiomers. The Journal of General Physiology. 101: 393-410. PMID 7682596 DOI: 10.1085/JGP.101.3.393 |
0.197 |
|
| 2018 |
Baburin I, Varkevisser R, Schramm A, Saxena P, Beyl S, Szkokan P, Linder T, Stary-Weinzinger A, van der Heyden MAG, Houtman M, Takanari H, Jonsson M, Beekman JHD, Hamburger M, Vos MA, ... Hering S, et al. Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are Iblockers with proarrhythmic effects in vitro and in vivo. Pharmacological Research. PMID 29477480 DOI: 10.1016/j.phrs.2018.02.024 |
0.197 |
|
| 1993 |
Strübing C, Hering S, Glossmann H. Evidence for an external location of the dihydropyridine agonist receptor site on smooth muscle and skeletal muscle calcium channels. British Journal of Pharmacology. 108: 884-91. PMID 7683566 DOI: 10.1111/j.1476-5381.1993.tb13482.x |
0.195 |
|
| 1996 |
Berjukow S, Döring F, Froschmayr M, Grabner M, Glossmann H, Hering S. Endogenous calcium channels in human embryonic kidney (HEK293) cells. British Journal of Pharmacology. 118: 748-54. PMID 8762103 DOI: 10.1111/J.1476-5381.1996.Tb15463.X |
0.192 |
|
| 2015 |
Goldmann D, Pakfeifer P, Hering S, Ecker GF. Novel scaffolds for modulation of TRPV1 identified with pharmacophore modeling and virtual screening. Future Medicinal Chemistry. 7: 243-56. PMID 25826358 DOI: 10.4155/Fmc.14.168 |
0.191 |
|
| 1996 |
Hering S, Aczél S, Grabner M, Döring F, Berjukow S, Mitterdorfer J, Sinnegger MJ, Striessnig J, Degtiar VE, Wang Z, Glossmann H. Transfer of high sensitivity for benzothiazepines from L-type to class A (BI) calcium channels. The Journal of Biological Chemistry. 271: 24471-5. PMID 8798706 DOI: 10.1074/Jbc.271.40.24471 |
0.186 |
|
| 2001 |
Berjukow S, Marksteiner R, Sokolov S, Weiss RG, Margreiter E, Hering S. Amino acids in segment IVS6 and beta-subunit interaction support distinct conformational changes during Ca(v)2.1 inactivation. The Journal of Biological Chemistry. 276: 17076-82. PMID 11350979 DOI: 10.1074/JBC.M010491200 |
0.175 |
|
| 2000 |
Sokolov S, Weiss RG, Timin EN, Hering S. Modulation of slow inactivation in class A Ca2+ channels by beta-subunits. The Journal of Physiology. 445-54. PMID 10990532 DOI: 10.1111/j.1469-7793.2000.t01-1-00445.x |
0.172 |
|
| 1996 |
Döring F, Degtiar VE, Grabner M, Striessnig J, Hering S, Glossman H. Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A. The Journal of Biological Chemistry. 271: 11745-9. PMID 8662622 DOI: 10.1074/Jbc.271.20.11745 |
0.17 |
|
| 2016 |
Li J, Casteels T, Frogne T, Ingvorsen C, Honoré C, Courtney M, Huber KV, Schmitner N, Kimmel RA, Romanov RA, Sturtzel C, Lardeau CH, Klughammer J, Farlik M, Sdelci S, ... ... Hering S, et al. Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity. Cell. PMID 27916275 DOI: 10.1016/J.Cell.2016.11.010 |
0.17 |
|
| 2000 |
Berjukow S, Marksteiner R, Gapp F, Sinnegger MJ, Hering S. Molecular mechanism of calcium channel block by isradipine. Role of a drug-induced inactivated channel conformation. The Journal of Biological Chemistry. 275: 22114-20. PMID 10766758 DOI: 10.1074/jbc.M908836199 |
0.169 |
|
| 2015 |
Grienke U, Mair CE, Saxena P, Baburin I, Scheel O, Ganzera M, Schuster D, Hering S, Rollinger JM. Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. Journal of Agricultural and Food Chemistry. 63: 5634-9. PMID 26035250 DOI: 10.1021/acs.jafc.5b01901 |
0.167 |
|
| 1999 |
Sokolov S, Weiss RG, Kurka B, Gapp F, Hering S. Inactivation determinant in the I-II loop of the Ca2+ channel alpha1-subunit and beta-subunit interaction affect sensitivity for the phenylalkylamine (-)gallopamil. The Journal of Physiology. 315-22. PMID 10457051 DOI: 10.1111/j.1469-7793.1999.0315m.x |
0.167 |
|
| 1990 |
Hughes AD, Hering S, Bolton TB. The action of caffeine on inward barium current through voltage-dependent calcium channels in single rabbit ear artery cells. Pflugers Archiv : European Journal of Physiology. 416: 462-6. PMID 1697946 DOI: 10.1007/BF00370755 |
0.165 |
|
| 2014 |
Saxena P, Linder T, Stary-Weinzinger A, IJzerman AP, Timin E, Franz Ecker G, Hering S. Insights into Molecular Basis of hERG Inhibition by Studying a Library of Dofetilide Derivatives Biophysical Journal. 106: 138a. DOI: 10.1016/J.Bpj.2013.11.806 |
0.163 |
|
| 2023 |
Baltov B, Beyl S, Baburin I, Reinhardt J, Szkokan P, Garifulina A, Timin E, Kraushaar U, Potterat O, Hamburger M, Kügler P, Hering S. Assay for evaluation of proarrhythmic effects of herbal products: Case study with 12 preparations. Toxicology Reports. 10: 589-599. PMID 37213814 DOI: 10.1016/j.toxrep.2023.04.014 |
0.157 |
|
| 1993 |
Glossmann H, Hering S, Savchenko A, Berger W, Friedrich K, Garcia ML, Goetz MA, Liesch JM, Zink DL, Kaczorowski GJ. A light stabilizer (Tinuvin 770) that elutes from polypropylene plastic tubes is a potent L-type Ca(2+)-channel blocker. Proceedings of the National Academy of Sciences of the United States of America. 90: 9523-7. PMID 8415734 DOI: 10.1073/Pnas.90.20.9523 |
0.153 |
|
| 1990 |
Kleppisch T, Timin EN, Bodewei R, Hering S. Receptor models of 1,4-dihydropyridine action on calcium channels in single cultured neonatal rat ventricular heart cells Journal of Molecular and Cellular Cardiology. 22: S18. DOI: 10.1016/0022-2828(90)91583-S |
0.149 |
|
| 2016 |
Saxena P, Zangerl-Plessl EM, Linder T, Windisch A, Hohaus A, Timin E, Hering S, Stary-Weinzinger A. New potential binding determinant for hERG channel inhibitors. Scientific Reports. 6: 24182. PMID 27067805 DOI: 10.1038/srep24182 |
0.149 |
|
| 2016 |
Saxena P, Hortigon-Vinagre M, Beyl S, Baburin I, Costa A, IJzerman AP, Kügler P, Timin E, Smith G, Hering S. On the Relation between HERG Channel Block in Cell Line and Action Potential Prolongation in Human iPSC Cardiomyocytes Biophysical Journal. 110: 527a. DOI: 10.1016/J.Bpj.2015.11.2819 |
0.145 |
|
| 1996 |
Grabner M, Wang Z, Hering S, Striessnig J, Glossmann H. Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels. Neuron. 16: 207-18. PMID 8562085 DOI: 10.1016/S0896-6273(00)80037-9 |
0.145 |
|
| 2017 |
Andranovits S, Beyl S, Hohaus A, Zangerl-Plessl EM, Timin E, Hering S. Key role of segment IS4 in Cav1.2 inactivation: link between activation and inactivation. Pflugers Archiv : European Journal of Physiology. 469: 1485-1493. PMID 28766141 DOI: 10.1007/s00424-017-2038-3 |
0.144 |
|
| 1995 |
Wang Z, Grabner M, Berjukow S, Savchenko A, Glossmann H, Hering S. Chimeric L-type Ca2+ channels expressed in Xenopus laevis oocytes reveal role of repeats III and IV in activation gating. The Journal of Physiology. 486: 131-7. PMID 7562629 DOI: 10.1113/Jphysiol.1995.Sp020797 |
0.144 |
|
| 1988 |
Hering S, Beech DJ, Bolton TB, Lim SP. Action of nifedipine or BAY K8644 is dependent on calcium channel state in single smooth muscle cells from rabbit ear artery. Pflugers Archiv : European Journal of Physiology. 411: 590-2. PMID 2455273 DOI: 10.1007/BF00582383 |
0.142 |
|
| 2001 |
Berjukow S, Hering S. Voltage-dependent acceleration of Ca(v)1.2 channel current decay by (+)- and (-)-isradipine. British Journal of Pharmacology. 133: 959-66. PMID 11487504 DOI: 10.1038/sj.bjp.0704181 |
0.14 |
|
| 1982 |
Bodewei R, Hering S, Lemke B, Rosenshtraukh LV, Undrovinas AI, Wollenberger A. Characterization of the fast sodium current in isolated rat myocardial cells: simulation of the clamped membrane potential The Journal of Physiology. 325: 301-315. PMID 7108778 DOI: 10.1113/jphysiol.1982.sp014151 |
0.139 |
|
| 1998 |
Striessnig J, Grabner M, Mitterdorfer J, Hering S, Sinnegger MJ, Glossmann H. Structural basis of drug binding to L Ca2+ channels. Trends in Pharmacological Sciences. 19: 108-15. PMID 9584627 DOI: 10.1016/S0165-6147(98)01171-7 |
0.138 |
|
| 2011 |
Beyl S, Depil K, Hohaus A, Stary-Weinzinger A, Timin E, Shabbir W, Kudrnac M, Hering S. Physicochemical properties of pore residues predict activation gating of Ca V1.2: a correlation mutation analysis. Pflugers Archiv : European Journal of Physiology. 461: 53-63. PMID 20924598 DOI: 10.1007/s00424-010-0885-2 |
0.137 |
|
| 1986 |
Schubert B, Hering S, Bodewei R, Rosenshtraukh LV, Wollenberger A. Use- and voltage-dependent depression by ethmozine (moricizine) of the rapid inward sodium current in single rat ventricular muscle cells. Journal of Cardiovascular Pharmacology. 8: 358-66. PMID 2422475 DOI: 10.1097/00005344-198603000-00019 |
0.136 |
|
| 1997 |
Hering S, Aczél S, Kraus RL, Berjukow S, Striessnig J, Timin EN. Molecular mechanism of use-dependent calcium channel block by phenylalkylamines: role of inactivation. Proceedings of the National Academy of Sciences of the United States of America. 94: 13323-8. PMID 9371844 DOI: 10.1073/Pnas.94.24.13323 |
0.135 |
|
| 2006 |
Baburin I, Beyl S, Hering S. Automated fast perfusion of Xenopus oocytes for drug screening. Pflugers Archiv : European Journal of Physiology. 453: 117-23. PMID 16953425 DOI: 10.1007/s00424-006-0125-y |
0.134 |
|
| 1986 |
Schubert B, Bodewei R, Hering S, Wollenberger A. A patch clamp study of the action of ethacyzine on the rapid inward sodium current in single rat heart muscle cells. European Journal of Pharmacology. 126: 309-12. PMID 2428635 DOI: 10.1016/0014-2999(86)90063-4 |
0.133 |
|
| 1983 |
Hering S, Bodewei R, Wollenberger A. Sodium current in freshly isolated and in cultured single rat myocardial cells: frequency and voltage-dependent block by mexiletine. Journal of Molecular and Cellular Cardiology. 15: 431-44. PMID 6620395 DOI: 10.1016/0022-2828(83)90263-8 |
0.133 |
|
| 2017 |
Saxena P, Hortigon-Vinagre MP, Beyl S, Baburin I, Andranovits S, Iqbal SM, Costa A, IJzerman AP, Kügler P, Timin E, Smith GL, Hering S. Correlation between hERG channel inhibition and action potential prolongation. British Journal of Pharmacology. PMID 28681507 DOI: 10.1111/Bph.13942 |
0.127 |
|
| 1996 |
Berjukov S, Aczel S, Beyer B, Kimball SD, Dichtl M, Hering S, Striessnig J. Extra- and intracellular action of quaternary devapamil on muscle L-type Ca(2+)-channels. British Journal of Pharmacology. 119: 1197-202. PMID 8937723 DOI: 10.1111/J.1476-5381.1996.Tb16022.X |
0.127 |
|
| 2012 |
Beyl S, Depil K, Hohaus A, Stary-Weinzinger A, Linder T, Timin E, Hering S. Neutralisation of a single voltage sensor affects gating determinants in all four pore-forming S6 segments of Ca(V)1.2: a cooperative gating model. PflüGers Archiv : European Journal of Physiology. 464: 391-401. PMID 22941337 DOI: 10.1007/s00424-012-1144-5 |
0.126 |
|
| 1995 |
Brauns T, Cai ZW, Kimball SD, Kang KC, Haugland RP, Berger W, Berjukov S, Hering S, Glossmann H, Striessnig J. Benzothiazepine binding domain of purified L-type calcium channels: direct labeling using a novel fluorescent diltiazem analogue. Biochemistry. 34: 3461-9. PMID 7880840 |
0.126 |
|
| 2002 |
Hering S. beta-Subunits: fine tuning of Ca(2+) channel block. Trends in Pharmacological Sciences. 23: 509-13. PMID 12413805 DOI: 10.1016/s0165-6147(02)02104-1 |
0.126 |
|
| 1996 |
Pichler M, Wang Z, Grabner-Weiss C, Reimer D, Hering S, Grabner M, Glossmann H, Striessnig J. Block of P/Q-type calcium channels by therapeutic concentrations of aminoglycoside antibiotics. Biochemistry. 35: 14659-64. PMID 8931565 DOI: 10.1021/Bi961657T |
0.125 |
|
| 2016 |
Kratz JM, Mair CE, Oettl SK, Saxena P, Scheel O, Schuster D, Hering S, Rollinger JM. hERG Channel Blocking Ipecac Alkaloids Identified by Combined In Silico - In Vitro Screening. Planta Medica. PMID 27145237 DOI: 10.1055/s-0042-105572 |
0.125 |
|
| 2019 |
Qile M, Beekman HDM, Sprenkeler DJ, Houtman MJC, van Ham WB, Stary-Weinzinger A, Beyl S, Hering S, van den Berg DJ, de Lange ECM, Heitman LH, IJzerman AP, Vos MA, van der Heyden MAG. LUF7244, an allosteric modulator/activator of K 11.1 channels, counteracts dofetilide-induced TdP arrhythmia in the chronic atrioventricular block dog model. British Journal of Pharmacology. PMID 31339551 DOI: 10.1111/Bph.14798 |
0.124 |
|
| 1991 |
Hughes AD, Hering S, Bolton TB. Evidence that agonist and antagonist enantiomers of the dihydropyridine PN 202-791 act at different sites on the voltage-dependent calcium channel of vascular muscle. British Journal of Pharmacology. 101: 3-5. PMID 2282463 DOI: 10.1111/j.1476-5381.1990.tb12076.x |
0.123 |
|
| 2019 |
Kalaba P, Ilić M, Aher NY, Dragačević V, Wieder M, Zehl M, Wackerlig J, Beyl S, Sartori SB, Ebner K, Roller A, Lukic N, Beryozkina TV, González ERP, Neill PJ, ... ... Hering S, et al. Structure Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters. Journal of Medicinal Chemistry. PMID 31841637 DOI: 10.1021/Acs.Jmedchem.9B01938 |
0.121 |
|
| 2000 |
Eller P, Berjukov S, Wanner S, Huber I, Hering S, Knaus HG, Toth G, Kimball SD, Striessnig J. High affinity interaction of mibefradil with voltage-gated calcium and sodium channels. British Journal of Pharmacology. 130: 669-77. PMID 10821797 DOI: 10.1038/Sj.Bjp.0703352 |
0.12 |
|
| 2014 |
Schramm A, Saxena P, Chlebek J, Cahlíková L, Baburin I, Hering S, Hamburger M. Natural products as potential human ether-a-go-go-related gene channel inhibitors - screening of plant-derived alkaloids. Planta Medica. 80: 740-6. PMID 24963621 DOI: 10.1055/s-0034-1368590 |
0.118 |
|
| 1998 |
Mitterdorfer J, Grabner M, Kraus RL, Hering S, Prinz H, Glossmann H, Striessnig J. Molecular basis of drug interaction with L-type Ca2+ channels. Journal of Bioenergetics and Biomembranes. 30: 319-34. PMID 9758329 DOI: 10.1023/A:1021933504909 |
0.115 |
|
| 2009 |
Schiesaro A, Richter L, Windisch A, Timin E, Hering S, Ecker GF. Docking into Symmetric Binding Sites: Problems and Solutions Exemplified on the hERG Potassium Channel Scientia Pharmaceutica. 77: 206-206. DOI: 10.3797/Scipharm.Oephg.21.Po-07 |
0.115 |
|
| 2016 |
Beyl S, Hohaus A, Andranovits S, Timin E, Hering S. Upward movement of IS4 and IIIS4 is a rate-limiting stage in Ca1.2 activation. Pflugers Archiv : European Journal of Physiology. 468: 1895-1907. PMID 27796578 DOI: 10.1007/s00424-016-1895-5 |
0.114 |
|
| 2004 |
Sinnegger-Brauns MJ, Hetzenauer A, Huber IG, Renström E, Wietzorrek G, Berjukov S, Cavalli M, Walter D, Koschak A, Waldschütz R, Hering S, Bova S, Rorsman P, Pongs O, Singewald N, et al. Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca 2+ channels. The Journal of Clinical Investigation. 113: 1430-9. PMID 15146240 DOI: 10.1172/Jci20208 |
0.112 |
|
| 1989 |
Hering S, Bolton TB, Beech DJ, Lim SP. Mechanism of calcium channel block by D600 in single smooth muscle cells from rabbit ear artery. Circulation Research. 64: 928-36. PMID 2539923 DOI: 10.1161/01.RES.64.5.928 |
0.111 |
|
| 2014 |
Vos M, Varkevisser R, Baburin I, Schramm A, van der Heyden M, Houtman M, Jonsson M, Takanari H, Beekman J, Hamburger M, Hering S. DEHYDROEVODIAMINE, ISOLATED FROM THE DRIED UNRIPE FRUIT OF EVODIA RUTAECARPA PRESENT IN THE TRADITIONAL CHINESE MEDICINE WU CHU YU, HAS PROARRHYTHMIC EFFECTS IN VITRO AND IN VIVO THAT DISAPPEAR AT HIGHER CONCENTRATIONS Heart Rhythm. 11: 2130. DOI: 10.1016/J.HRTHM.2014.09.015 |
0.11 |
|
| 2014 |
Kratz JM, Schuster D, Edtbauer M, Saxena P, Mair CE, Kirchebner J, Matuszczak B, Baburin I, Hering S, Rollinger JM. Experimentally validated HERG pharmacophore models as cardiotoxicity prediction tools. Journal of Chemical Information and Modeling. 54: 2887-901. PMID 25148533 DOI: 10.1021/ci5001955 |
0.109 |
|
| 2010 |
Thai KM, Windisch A, Stork D, Weinzinger A, Schiesaro A, Guy RH, Timin EN, Hering S, Ecker GF. The hERG potassium channel and drug trapping: Insight from docking studies with propafenone derivatives Chemmedchem. 5: 436-442. PMID 20146282 DOI: 10.1002/Cmdc.200900374 |
0.108 |
|
| 2005 |
Hohaus A, Beyl S, Kudrnac M, Berjukow S, Timin EN, Marksteiner R, Maw MA, Hering S. Structural determinants of L-type channel activation in segment IIS6 revealed by a retinal disorder. The Journal of Biological Chemistry. 280: 38471-7. PMID 16157588 DOI: 10.1074/jbc.M507013200 |
0.107 |
|
| 2000 |
Hering S, Berjukow S, Sokolov S, Marksteiner R, Weiss RG, Kraus R, Timin EN. Molecular determinants of inactivation in voltage-gated Ca2+ channels. The Journal of Physiology. 237-49. PMID 11034614 DOI: 10.1111/j.1469-7793.2000.t01-1-00237.x |
0.106 |
|
| 2014 |
Schramm A, Jähne EA, Baburin I, Hering S, Hamburger M. Natural products as potential human ether-a-go-go-related gene channel inhibitors - outcomes from a screening of widely used herbal medicines and edible plants. Planta Medica. 80: 1045-50. PMID 25089737 DOI: 10.1055/s-0034-1382907 |
0.106 |
|
| 2016 |
Saxena P, Hortigon-Vinagre MP, Costa A, Timin E, Beyl S, Baburin I, Smith GL, Hering S. Comparison of HERG ion channel effects in HEK cells and action potential duration in human iPSC cardiomyocytes Journal of Pharmacological and Toxicological Methods. 81: 347. DOI: 10.1016/J.Vascn.2016.02.041 |
0.105 |
|
| 1999 |
Aczél S, Kurka B, Hering S. Mechanism of voltage- and use-dependent block of class A Ca2+ channels by mibefradil. British Journal of Pharmacology. 125: 447-54. PMID 9806326 DOI: 10.1038/sj.bjp.0702092 |
0.104 |
|
| 1998 |
Kraus RL, Sinnegger MJ, Glossmann H, Hering S, Striessnig J. Familial hemiplegic migraine mutations change alpha1A Ca2+ channel kinetics. The Journal of Biological Chemistry. 273: 5586-90. PMID 9488686 DOI: 10.1074/Jbc.273.10.5586 |
0.104 |
|
| 2009 |
Kudrnac M, Beyl S, Hohaus A, Stary A, Peterbauer T, Timin E, Hering S. Independent Contributions Of Segments IS6 And IIS6 To Activation Gating Of CaV1.2 Biophysical Journal. 96: 184a. DOI: 10.1016/J.BPJ.2008.12.863 |
0.104 |
|
| 2010 |
Beyl S, Hohaus A, Timin E, Hering S. Activation Gating Determinants in Segments IS6 - IIIS6 of Cav1.2 Biophysical Journal. 98: 516a. DOI: 10.1016/j.bpj.2009.12.2809 |
0.101 |
|
| 2009 |
Windisch A, Schiesaro A, Thai K-, Timin E, Hohaus A, Ecker GF, Hering S. Ligand Determinants of Drug Trapping in hERG Potassium Channels Scientia Pharmaceutica. 77: 226-226. DOI: 10.3797/Scipharm.Oephg.21.Po-27 |
0.1 |
|
| 2007 |
Stork D, Timin EN, Berjukow S, Huber C, Hohaus A, Auer M, Hering S. State dependent dissociation of HERG channel inhibitors. British Journal of Pharmacology. 151: 1368-76. PMID 17592502 DOI: 10.1038/sj.bjp.0707356 |
0.1 |
|
| 2013 |
Beyl S, Kügler P, Hohaus A, Depil K, Hering S, Timin E. Methods for quantification of pore-voltage sensor interaction in Ca(V)1.2. Pflugers Archiv : European Journal of Physiology. 466: 265-74. PMID 23873350 DOI: 10.1007/s00424-013-1319-8 |
0.099 |
|
| 2010 |
Karmazinova M, Beyl S, Stary-Weinzinger A, Suwattanasophon C, Klugbauer N, Hering S, Lacinova L. Cysteines in the loop between IS5 and the pore helix of Ca(V)3.1 are essential for channel gating. Pflugers Archiv : European Journal of Physiology. 460: 1015-28. PMID 20827487 DOI: 10.1007/s00424-010-0874-5 |
0.098 |
|
| 1988 |
Schubert B, Bodewei R, Hering S, Wollenberger A. Cell-attached patch clamp measurement of macroscopic rapid inward sodium current in cultured heart cell reaggregates. Journal of Molecular and Cellular Cardiology. 19: 1129-39. PMID 2449533 DOI: 10.1016/S0022-2828(87)80356-5 |
0.098 |
|
| 2016 |
Beyl S, Hohaus A, Adranovits S, Timin E, Hering S. Different Roles of IS4 and IIS4 Segments in CaV1.2 Gating Biophysical Journal. 110: 443a. DOI: 10.1016/J.BPJ.2015.11.2384 |
0.097 |
|
| 1980 |
Undrovinas AI, Yushmanova AV, Hering S, Rosenshtraukh LV. Voltage clamp method on single cardiac cells from adult rat heart. Experientia. 36: 572-4. PMID 7379958 DOI: 10.1007/BF01965808 |
0.096 |
|
| 2005 |
Hemara-Wahanui A, Berjukow S, Hope CI, Dearden PK, Wu SB, Wilson-Wheeler J, Sharp DM, Lundon-Treweek P, Clover GM, Hoda JC, Striessnig J, Marksteiner R, Hering S, Maw MA. A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation. Proceedings of the National Academy of Sciences of the United States of America. 102: 7553-8. PMID 15897456 DOI: 10.1073/pnas.0501907102 |
0.094 |
|
| 2011 |
Windisch A, Timin E, Schwarz T, Stork-Riedler D, Erker T, Ecker G, Hering S. Trapping and dissociation of propafenone derivatives in HERG channels British Journal of Pharmacology. 162: 1542-1552. PMID 21175572 DOI: 10.1111/J.1476-5381.2010.01159.X |
0.093 |
|
| 2007 |
Beyl S, Timin EN, Hohaus A, Stary A, Kudrnac M, Guy RH, Hering S. Probing the architecture of an L-type calcium channel with a charged phenylalkylamine: evidence for a widely open pore and drug trapping. The Journal of Biological Chemistry. 282: 3864-70. PMID 17138559 DOI: 10.1074/jbc.M609153200 |
0.093 |
|
| 2001 |
Sokolov S, Timin E, Hering S. On the role of Ca(2+)- and voltage-dependent inactivation in Ca(v)1.2 sensitivity for the phenylalkylamine (-)gallopamil. Circulation Research. 89: 700-8. PMID 11597993 DOI: 10.1161/HH2001.098983 |
0.092 |
|
| 2011 |
Shabbir W, Beyl S, Timin EN, Schellmann D, Erker T, Hohaus A, Hockerman GH, Hering S. Interaction of diltiazem with an intracellularly accessible binding site on Ca(V)1.2. British Journal of Pharmacology. 162: 1074-82. PMID 20973779 DOI: 10.1111/j.1476-5381.2010.01091.x |
0.092 |
|
| 2016 |
Linder T, Bernsteiner H, Saxena P, Bauer F, Erker T, Timin E, Hering S, Stary-Weinzinger A. Drug trapping in hERG K channels: (not) a matter of drug size? Medchemcomm. 7: 512-518. PMID 28337337 DOI: 10.1039/c5md00443h |
0.091 |
|
| 2011 |
Depil K, Beyl S, Stary-Weinzinger A, Hohaus A, Timin E, Hering S. Timothy mutation disrupts the link between activation and inactivation in Ca(V)1.2 protein. The Journal of Biological Chemistry. 286: 31557-64. PMID 21685391 DOI: 10.1074/jbc.M111.255273 |
0.09 |
|
| 2001 |
Marksteiner R, Schurr P, Berjukow S, Margreiter E, Perez-Reyes E, Hering S. Inactivation determinants in segment IIIS6 of Ca(v)3.1. The Journal of Physiology. 537: 27-34. PMID 11711558 DOI: 10.1111/j.1469-7793.2001.0027k.x |
0.089 |
|
| 2018 |
Hering S, Zangerl-Plessl EM, Beyl S, Hohaus A, Andranovits S, Timin EN. Calcium channel gating. Pflugers Archiv : European Journal of Physiology. 470: 1291-1309. PMID 29951751 DOI: 10.1007/s00424-018-2163-7 |
0.089 |
|
| 2009 |
Beyl S, Kügler P, Kudrnac M, Hohaus A, Hering S, Timin E. Different pathways for activation and deactivation in CaV1.2: a minimal gating model. The Journal of General Physiology. 134: 231-41; S1-2. PMID 19687230 DOI: 10.1085/jgp.200910272 |
0.088 |
|
| 2013 |
Saxena P, Erker T, Bauer F, Stary-Weinzinger A, Linder T, Hering S, Timin E. Drug Trapping in hERG Channels does not Require Closure of the Activation Gate Biophysical Journal. 104: 266a. DOI: 10.1016/J.BPJ.2012.11.1493 |
0.086 |
|
| 1992 |
Timin EN, Hering S. A method for estimation of drug affinity constants to the open conformational state of calcium channels. Biophysical Journal. 63: 808-14. PMID 1330037 DOI: 10.1016/S0006-3495(92)81636-3 |
0.086 |
|
| 1998 |
Hering S. Small-volume and rapid extracellular solution exchange around Xenopus oocytes during voltage-clamp recordings. Pflugers Archiv : European Journal of Physiology. 436: 303-7. PMID 9594032 DOI: 10.1007/s004240050636 |
0.086 |
|
| 1986 |
SCHUBERT B, HERING S, BODEWEI R. Patch voltage clamp measurement of ionic currents in cultured heart cell reaggregates Journal of Molecular and Cellular Cardiology. 18: 70-70. DOI: 10.1016/S0022-2828(86)80688-5 |
0.085 |
|
| 2011 |
Böhmdorfer M, Maier-Salamon A, Taferner B, Reznicek G, Thalhammer T, Hering S, Hüfner A, Schühly W, Jäger W. In vitro metabolism and disposition of honokiol in rat and human livers. Journal of Pharmaceutical Sciences. 100: 3506-3516. PMID 21404278 DOI: 10.1002/jps.22536 |
0.084 |
|
| 2014 |
Linder T, Saxena P, Timin E, Hering S, Stary-Weinzinger A. Structural insights into trapping and dissociation of small molecules in K⁺ channels. Journal of Chemical Information and Modeling. 54: 3218-28. PMID 25297379 DOI: 10.1021/ci500353r |
0.081 |
|
| 2009 |
Kudrnac M, Beyl S, Hohaus A, Stary A, Peterbauer T, Timin E, Hering S. Coupled and independent contributions of residues in IS6 and IIS6 to activation gating of CaV1.2. The Journal of Biological Chemistry. 284: 12276-84. PMID 19265197 DOI: 10.1074/jbc.M808402200 |
0.08 |
|
| 2015 |
Wilhelm A, van der Westhuizen J, Phungula K, van Rensburg E, Zietsman P, Hering S. An investigation into consumed South African plant species as potential hERG channel blockers Planta Medica. 81. DOI: 10.1055/s-0035-1565737 |
0.076 |
|
| 2008 |
Stary A, Kudrnac M, Beyl S, Hohaus A, Timin EN, Wolschann P, Guy HR, Hering S. Molecular dynamics and mutational analysis of a channelopathy mutation in the IIS6 helix of Ca V 1.2. Channels (Austin, Tex.). 2: 216-23. PMID 18836301 DOI: 10.4161/chan.2.3.6160 |
0.074 |
|
| 2013 |
Kratz J, Edtbauer M, Mair C, Hering S, Schuster D, Rollinger J. Pharmacophore-based identification of novel hERG channel blockers of natural origin - Development of a virtual screening workflow and experimental validation Planta Medica. 79. DOI: 10.1055/S-0033-1351851 |
0.073 |
|
| 2011 |
Schramm A, Baburin I, Hering S, Hamburger M. Risk assessment of hERG channel inhibition by natural products – screening and activity directed analysis of spices, food and medicinal plants Planta Medica. 77. DOI: 10.1055/S-0031-1282100 |
0.066 |
|
| 2008 |
Stary A, Shafrir Y, Hering S, Wolschann P, Guy HR. Structural model of the Ca V 1.2 pore. Channels (Austin, Tex.). 2: 210-5. PMID 18836302 DOI: 10.4161/Chan.2.3.6158 |
0.064 |
|
| 1988 |
Hering S, Beech DJ, Bolton TB. A simple method of fast extracellular solution exchange for the study of whole-cell or single channel currents using patch-clamp technique. Pflugers Archiv : European Journal of Physiology. 410: 335-7. PMID 2446257 DOI: 10.1007/BF00580285 |
0.064 |
|
| 2011 |
Depil K, Beyl S, Stary-Weinzinger A, Hohaus A, Timin E, Hering S. Timothy mutation affects tightly sealing point of CaV1.2 activation gate Bmc Pharmacology. 11. DOI: 10.1186/1471-2210-11-S2-A12 |
0.063 |
|
| 2008 |
Hering S, Beyl S, Stary A, Kudrnac M, Hohaus A, Guy HR, Timin E. Pore stability and gating in voltage-activated calcium channels. Channels (Austin, Tex.). 2: 61-9. PMID 18849656 DOI: 10.4161/chan.2.2.5999 |
0.063 |
|
| 1986 |
Schubert B, Hering S, Bodewei R, Wollenberger A. Frequency-dependent blockade of Na channels of isolated rat cariomyocytes by the antiarrhythmic ethmozine Bulletin of Experimental Biology and Medicine. 101: 638-640. DOI: 10.1007/BF00835885 |
0.058 |
|
| 2011 |
Svoboda M, Wlcek K, Taferner B, Hering S, Stieger B, Tong D, Zeillinger R, Thalhammer T, Jäger W. Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 65: 417-26. PMID 21719246 DOI: 10.1016/j.biopha.2011.04.031 |
0.056 |
|
| 2016 |
Kratz JM, Mair CE, Oettl SK, Saxena P, Scheel O, Schuster D, Hering S, Rollinger JM. Pick your poison: hERG-blocking alkaloids in the emetic herbal drug ipecac. Planta Medica. 81: S1-S381. PMID 27976234 DOI: 10.1055/s-0036-1597035 |
0.056 |
|
| 2014 |
Grienke U, Mair C, Saxena P, Kratz J, Baburin I, Schuster D, Hering S, Rollinger J. The 'Lotus Leave Diet' – A life-threatening experience? hERG channel blocking aporphine alkaloids from Nelumbo nucifera Gaertn Planta Medica. 80. DOI: 10.1055/S-0034-1394533 |
0.056 |
|
| 1995 |
Savchenko A, Glossmann H, Hering S. Improved micro-perfusion chamber for multiple and rapid solution exchange in adherent single cells. Pflã¼Gers Archiv : European Journal of Physiology. 429: 436-42. PMID 7539128 DOI: 10.1007/Bf00374161 |
0.051 |
|
| 2005 |
Ott HC, Kroess R, Bonaros N, Marksteiner R, Margreiter E, Schachner T, Laufer G, Hering S. Intramyocardial microdepot injection increases the efficacy of skeletal myoblast transplantation. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 27: 1017-21. PMID 15896611 DOI: 10.1016/j.ejcts.2005.01.065 |
0.05 |
|
| 2007 |
Stork D, Windisch A, Timin EN, Hohaus A, Auer M, Ecker G, Hering S. State-dependent dissociation of HERG channel inhibitors Bmc Pharmacology. 7: A13. DOI: 10.1186/1471-2210-7-S2-A13 |
0.049 |
|
| 2009 |
Beyl S, Kuegler P, Kudrnac M, Hohaus A, Hering S, Timin E. Membrane Voltage More Efficient In Closing Than Opening CaV1.2? Biophysical Journal. 96: 180a. DOI: 10.1016/J.BPJ.2008.12.840 |
0.049 |
|
| 2015 |
Carl D, Grüllich C, Hering S, Schabet M. Steroid responsive encephalopathy associated with autoimmune thyroiditis following ipilimumab therapy: a case report. Bmc Research Notes. 8: 316. PMID 26209970 DOI: 10.1186/s13104-015-1283-9 |
0.049 |
|
| 2004 |
Berjukow S, Margreiter E, Marksteiner R, Strasser H, Bartsch G, Hering S. Membrane properties of single muscle cells of the rhabdosphincter of the male urethra. The Prostate. 58: 238-47. PMID 14743462 DOI: 10.1002/pros.10334 |
0.048 |
|
| 2011 |
Beyl S, Shabbir W, Timin E, Schellmann D, Erker T, Hohaus A, Hockerman GH, Hering S. Interaction of Diltiazem with an Intracellularly Accessible Binding Site on CaV1.2 Biophysical Journal. 100: 568a. DOI: 10.1016/j.bpj.2010.12.3295 |
0.043 |
|
| 1999 |
Hering S, Berjukow S, Aczél S, Timin EN. Ca2+ channel block and inactivation: common molecular determinants. Trends in Pharmacological Sciences. 19: 439-43. PMID 9850606 DOI: 10.1016/S0165-6147(98)01258-9 |
0.039 |
|
| 2023 |
Schmidt C, Deyett A, Ilmer T, Haendeler S, Torres Caballero A, Novatchkova M, Netzer MA, Ceci Ginistrelli L, Mancheno Juncosa E, Bhattacharya T, Mujadzic A, Pimpale L, Jahnel SM, Cirigliano M, Reumann D, ... ... Hering S, et al. Multi-chamber cardioids unravel human heart development and cardiac defects. Cell. PMID 38029745 DOI: 10.1016/j.cell.2023.10.030 |
0.038 |
|
| 2016 |
Linder T, Bernsteiner H, Saxena P, Bauer F, Erker T, Timin E, Hering S, Stary-Weinzinger A. Drug trapping in hERG K+ channels: (Not) a matter of drug size? Medchemcomm. 7: 512-518. DOI: 10.1039/c5md00443h |
0.035 |
|
| 2017 |
Chatzitomaris A, Hoermann R, Midgley JE, Hering S, Urban A, Dietrich B, Abood A, Klein HH, Dietrich JW. Thyroid Allostasis-Adaptive Responses of Thyrotropic Feedback Control to Conditions of Strain, Stress, and Developmental Programming. Frontiers in Endocrinology. 8: 163. PMID 28775711 DOI: 10.3389/Fendo.2017.00163 |
0.034 |
|
| 1987 |
HERING S, BEECH D, BOLTON T. The mechanism of calcium channel blockade by D600 and nifedipine in single smoothmuscle cells of rabbit ear artery Journal of Molecular and Cellular Cardiology. 19: S33-S33. DOI: 10.1016/S0022-2828(87)80107-4 |
0.034 |
|
| 2006 |
Peterbauer T, Heitz J, Olbrich M, Hering S. Simple and versatile methods for the fabrication of arrays of live mammalian cells. Lab On a Chip. 6: 857-63. PMID 16804589 DOI: 10.1039/b601803c |
0.033 |
|
| 2008 |
Dietrich JW, Stachon A, Antic B, Klein HH, Hering S. The AQUA-FONTIS study: protocol of a multidisciplinary, cross-sectional and prospective longitudinal study for developing standardized diagnostics and classification of non-thyroidal illness syndrome. Bmc Endocrine Disorders. 8: 13. PMID 18851740 DOI: 10.1186/1472-6823-8-13 |
0.029 |
|
| 2011 |
Pennekamp W, Roggenland D, Hering S, Lemburg S, Peters S, Sterl S, Schwenke C, Nicolas V. Intra-individual, randomised comparison of the MRI contrast agents gadobutrol and gadoterate in imaging the distal lower limb of patients with known or suspected osteomyelitis, evaluated in an off-site blinded read. European Radiology. 21: 1058-67. PMID 21174098 DOI: 10.1007/s00330-010-2008-z |
0.029 |
|
| 2008 |
Rebollar E, Frischauf I, Olbrich M, Peterbauer T, Hering S, Preiner J, Hinterdorfer P, Romanin C, Heitz J. Proliferation of aligned mammalian cells on laser-nanostructured polystyrene. Biomaterials. 29: 1796-806. PMID 18237776 DOI: 10.1016/j.biomaterials.2007.12.039 |
0.029 |
|
| 2012 |
Beyl S, Depil K, Hohaus A, Stary-Weinzinger A, Timin E, Hering S. Neutralizing the Charges in a Voltage Sensor Repairs Gating Perturbations in the Pore of CaV1.2 Biophysical Journal. 102: 126a. DOI: 10.1016/j.bpj.2011.11.704 |
0.027 |
|
| 2008 |
Mitterberger M, Pinggera GM, Marksteiner R, Margreiter E, Fussenegger M, Frauscher F, Ulmer H, Hering S, Bartsch G, Strasser H. Adult stem cell therapy of female stress urinary incontinence. European Urology. 53: 169-75. PMID 17683852 DOI: 10.1016/j.eururo.2007.07.026 |
0.026 |
|
| 2011 |
Weinzinger A, Depil K, Beyl S, Timin E, Hering S. Mutational Analysis in the Bundle Crossing Region Guides the Design of Cav1.2 Homology Models Biophysical Journal. 100: 569a. DOI: 10.1016/J.BPJ.2010.12.3298 |
0.024 |
|
| 2013 |
Schuster D, Edtbauer M, Kratz JM, Mair CE, Hering S, Rollinger JM. Pharmacophore-based virtual screening as a prioritization tool to assess mechanism-based cardiotoxic effects of small organic molecules Toxicology Letters. 221: S84. DOI: 10.1016/J.TOXLET.2013.05.095 |
0.021 |
|
| 2020 |
Thurner M, Deutsch M, Janke K, Messner F, Kreutzer C, Beyl S, Couillard-Després S, Hering S, Troppmair J, Marksteiner R. Generation of myogenic progenitor cell-derived smooth muscle cells for sphincter regeneration. Stem Cell Research & Therapy. 11: 233. PMID 32532320 DOI: 10.1186/S13287-020-01749-W |
0.021 |
|
| 2010 |
Manolopoulos KN, Barthel A, Nicolas V, Klein HH, Hering S. Necrotizing fasciitis of the back musculature as a complication of acquired perforating collagenosis in diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. 95: 11-2. PMID 20056807 DOI: 10.1210/jc.2009-1621 |
0.01 |
|
| 2008 |
Stachon A, Segbers E, Hering S, Kempf R, Holland-Letz T, Krieg M. A laboratory-based risk score for medical intensive care patients. Clinical Chemistry and Laboratory Medicine. 46: 855-62. PMID 18601610 DOI: 10.1515/CCLM.2008.136 |
0.01 |
|
| 2007 |
Stachon A, Segbers E, Holland-Letz T, Kempf R, Hering S, Krieg M. Nucleated red blood cells in the blood of medical intensive care patients indicate increased mortality risk: a prospective cohort study. Critical Care (London, England). 11: R62. PMID 17550592 DOI: 10.1186/cc5932 |
0.01 |
|
| 2006 |
Bonaros N, Rauf R, Wolf D, Margreiter E, Tzankov A, Schlechta B, Kocher A, Ott H, Schachner T, Hering S, Bonatti J, Laufer G. Combined transplantation of skeletal myoblasts and angiopoietic progenitor cells reduces infarct size and apoptosis and improves cardiac function in chronic ischemic heart failure. The Journal of Thoracic and Cardiovascular Surgery. 132: 1321-8. PMID 17140950 DOI: 10.1016/j.jtcvs.2006.07.023 |
0.01 |
|
| 2004 |
Strasser H, Berjukow S, Marksteiner R, Margreiter E, Hering S, Bartsch G, Hering S. Stem cell therapy for urinary stress incontinence. Experimental Gerontology. 39: 1259-65. PMID 15489048 DOI: 10.1016/j.exger.2004.07.003 |
0.01 |
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