| Year |
Citation |
Score |
| 2023 |
Hoertel N, Rezaei K, Sánchez-Rico M, Delgado-Álvarez A, Kornhuber J, Gulbins E, Olfson M, Ouazana-Vedrines C, Carpinteiro A, Cougoule C, Becker KA, Alvarado JM, Limosin F. Medications Modulating the Acid Sphingomyelinase/Ceramide System and 28-Day Mortality among Patients with SARS-CoV-2: An Observational Study. Pharmaceuticals (Basel, Switzerland). 16. PMID 37631022 DOI: 10.3390/ph16081107 |
0.325 |
|
| 2023 |
Choi BJ, Park MH, Park KH, Han WH, Yoon HJ, Jung HY, Hong JY, Chowdhury MR, Kim KY, Lee J, Song IS, Pang M, Choi MK, Gulbins E, Reichel M, et al. Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer's disease. Nature Communications. 14: 1631. PMID 36959217 DOI: 10.1038/s41467-023-37316-z |
0.34 |
|
| 2022 |
Péricat D, Leon-Icaza SA, Sanchez Rico M, Mühle C, Zoicas I, Schumacher F, Planès R, Mazars R, Gros G, Carpinteiro A, Becker KA, Izopet J, Strub-Wourgaft N, Sjö P, Neyrolles O, ... ... Gulbins E, et al. Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model. International Journal of Molecular Sciences. 23. PMID 36362409 DOI: 10.3390/ijms232113623 |
0.361 |
|
| 2022 |
Hoertel N, Sánchez-Rico M, Kornhuber J, Gulbins E, Reiersen AM, Lenze EJ, Fritz BA, Jalali F, Mills EJ, Cougoule C, Carpinteiro A, Mühle C, Becker KA, Boulware DR, Blanco C, et al. Antidepressant Use and Its Association with 28-Day Mortality in Inpatients with SARS-CoV-2: Support for the FIASMA Model against COVID-19. Journal of Clinical Medicine. 11. PMID 36233753 DOI: 10.3390/jcm11195882 |
0.301 |
|
| 2022 |
Edwards MJ, Wilson GC, Keitsch S, Soddemann M, Wilker B, Müller CP, Kornhuber J, Gulbins E. Molecular targets of endothelial phosphatidic acid regulating major depressive disorder. Journal of Neurochemistry. PMID 36227646 DOI: 10.1111/jnc.15708 |
0.4 |
|
| 2022 |
Schumacher F, Carpinteiro A, Edwards MJ, Wilson GC, Keitsch S, Soddemann M, Wilker B, Kleuser B, Becker KA, Müller CP, Kornhuber J, Gulbins E. Stress induces major depressive disorder by a neutral sphingomyelinase 2-mediated accumulation of ceramide-enriched exosomes in the blood plasma. Journal of Molecular Medicine (Berlin, Germany). PMID 36045177 DOI: 10.1007/s00109-022-02250-y |
0.365 |
|
| 2022 |
Schumacher F, Edwards MJ, Mühle C, Carpinteiro A, Wilson G, Wilker B, Soddemann M, Keitsch S, Scherbaum N, Müller BW, Lang UE, Linnemann C, Kleuser B, Müller CP, Kornhuber J, ... Gulbins E, et al. Ceramide levels in blood plasma correlate with major depressive disorder severity and its neutralization abrogates depressive behavior in mice. The Journal of Biological Chemistry. 102185. PMID 35753355 DOI: 10.1016/j.jbc.2022.102185 |
0.391 |
|
| 2022 |
Kalinichenko LS, Gulbins E, Kornhuber J, Müller CP. Sphingolipid control of cognitive functions in health and disease. Progress in Lipid Research. 86: 101162. PMID 35318099 DOI: 10.1016/j.plipres.2022.101162 |
0.321 |
|
| 2021 |
Kornhuber J, Hoertel N, Gulbins E. The acid sphingomyelinase/ceramide system in COVID-19. Molecular Psychiatry. PMID 34608263 DOI: 10.1038/s41380-021-01309-5 |
0.39 |
|
| 2021 |
Kalinichenko LS, Mühle C, Jia T, Anderheiden F, Datz M, Eberle AL, Eulenburg V, Granzow J, Hofer M, Hohenschild J, Huber SE, Kämpf S, Kogias G, Lacatusu L, Lugmair C, ... ... Gulbins E, et al. Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects. Molecular Psychiatry. PMID 34584229 DOI: 10.1038/s41380-021-01304-w |
0.319 |
|
| 2021 |
Kornhuber J, Gulbins E. New Molecular Targets for Antidepressant Drugs. Pharmaceuticals (Basel, Switzerland). 14. PMID 34577594 DOI: 10.3390/ph14090894 |
0.329 |
|
| 2021 |
Hoertel N, Sánchez-Rico M, Cougoule C, Gulbins E, Kornhuber J, Carpinteiro A, Becker KA, Reiersen AM, Lenze EJ, Seftel D, Lemogne C, Limosin F. Repurposing antidepressants inhibiting the sphingomyelinase acid/ceramide system against COVID-19: current evidence and potential mechanisms. Molecular Psychiatry. PMID 34385600 DOI: 10.1038/s41380-021-01254-3 |
0.341 |
|
| 2021 |
Rhein C, Zoicas I, Marx LM, Zeitler S, Hepp T, von Zimmermann C, Mühle C, Richter-Schmidinger T, Lenz B, Erim Y, Reichel M, Gulbins E, Kornhuber J. mRNA Expression of Encoding Acid Sphingomyelinase Decreases upon Antidepressant Treatment. International Journal of Molecular Sciences. 22. PMID 34071826 DOI: 10.3390/ijms22115700 |
0.367 |
|
| 2021 |
Carpinteiro A, Gripp B, Hoffmann M, Pöhlmann S, Hoertel N, Edwards MJ, Kamler M, Kornhuber J, Becker KA, Gulbins E. Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells. The Journal of Biological Chemistry. 100701. PMID 33895135 DOI: 10.1016/j.jbc.2021.100701 |
0.401 |
|
| 2021 |
Becker KA, Carpinteiro A, Hoffmann M, Pöhlmann S, Kornhuber J, Gulbins E. assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells. Star Protocols. 2: 100356. PMID 33558862 DOI: 10.1016/j.xpro.2021.100356 |
0.346 |
|
| 2020 |
Carpinteiro A, Edwards MJ, Hoffmann M, Kochs G, Gripp B, Weigang S, Adams C, Carpinteiro E, Gulbins A, Keitsch S, Sehl C, Soddemann M, Wilker B, Kamler M, Bertsch T, ... ... Gulbins E, et al. Pharmacological inhibition of acid sphingomyelinase prevents uptake of SARS-CoV-2 by epithelial cells. Cell Reports. Medicine. 100142. PMID 33163980 DOI: 10.1016/j.xcrm.2020.100142 |
0.385 |
|
| 2020 |
Kalinichenko LS, Abdel-Hafiz L, Wang AL, Mühle C, Rösel N, Schumacher F, Kleuser B, Smaga I, Frankowska M, Filip M, Schaller G, Richter-Schmidinger T, Lenz B, Gulbins E, Kornhuber J, et al. Neutral Sphingomyelinase is an Affective Valence-Dependent Regulator of Learning and Memory. Cerebral Cortex (New York, N.Y. : 1991). PMID 33043975 DOI: 10.1093/cercor/bhaa298 |
0.306 |
|
| 2020 |
Kalinichenko LS, Wang AL, Mühle C, Abdel-Hafiz L, Gulbins E, Kornhuber J, Oliveira AWC, Barros M, Huston JP, Müller CP. Neutral ceramidase is a marker for cognitive performance in rats and monkeys. Pharmacological Reports : Pr. PMID 32936422 DOI: 10.1007/S43440-020-00159-2 |
0.422 |
|
| 2020 |
Frankowska M, Jesus FM, Mühle C, Pacheco JVN, Maior RS, Sadakierska-Chudy A, Smaga I, Piechota M, Kalinichenko LS, Gulbins E, Kornhuber J, Filip M, Müller CP, Barros M. Cocaine attenuates acid sphingomyelinase activity during establishment of addiction-related behavior-A translational study in rats and monkeys. Addiction Biology. e12955. PMID 32761719 DOI: 10.1111/Adb.12955 |
0.386 |
|
| 2020 |
Gardner AI, Haq IJ, Simpson AJ, Becker KA, Gallagher J, Saint-Criq V, Verdon B, Mavin E, Trigg A, Gray MA, Koulman A, McDonnell MJ, Fisher AJ, Kramer EL, Clancy JP, ... ... Gulbins E, et al. Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 32569477 DOI: 10.1164/Rccm.202001-0180Oc |
0.351 |
|
| 2020 |
Zoicas I, Schumacher F, Kleuser B, Reichel M, Gulbins E, Fejtova A, Kornhuber J, Rhein C. The Forebrain-Specific Overexpression of Acid Sphingomyelinase Induces Depressive-Like Symptoms in Mice. Cells. 9. PMID 32443534 DOI: 10.3390/Cells9051244 |
0.443 |
|
| 2020 |
Zoicas I, Mühle C, Schmidtner AK, Gulbins E, Neumann ID, Kornhuber J. Anxiety and Depression Are Related to Higher Activity of Sphingolipid Metabolizing Enzymes in the Rat Brain. Cells. 9. PMID 32429522 DOI: 10.3390/Cells9051239 |
0.411 |
|
| 2020 |
Verhaegh R, Becker KA, Edwards MJ, Gulbins E. Sphingosine kills bacteria by binding to cardiolipin. The Journal of Biological Chemistry. PMID 32327486 DOI: 10.1074/Jbc.Ra119.012325 |
0.314 |
|
| 2020 |
Lang J, Bohn P, Bhat H, Jastrow H, Walkenfort B, Cansiz F, Fink J, Bauer M, Olszewski D, Ramos-Nascimento A, Duhan V, Friedrich SK, Becker KA, Krawczyk A, Edwards MJ, ... ... Gulbins E, et al. Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease. Nature Communications. 11: 1338. PMID 32165633 DOI: 10.1038/S41467-020-15072-8 |
0.303 |
|
| 2020 |
Naser E, Kadow S, Schumacher F, Mohamed ZH, Kappe C, Hessler G, Pollmeier B, Kleuser B, Arenz C, Becker KA, Gulbins E, Carpinteiro A. Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase . Journal of Lipid Research. PMID 32156719 DOI: 10.1194/Jlr.Ra120000682 |
0.337 |
|
| 2019 |
Beckmann N, Becker KA, Kadow S, Schumacher F, Kramer M, Kühn C, Schulz-Schaeffer WJ, Edwards MJ, Kleuser B, Gulbins E, Carpinteiro A. Acid Sphingomyelinase Deficiency Ameliorates Farber Disease. International Journal of Molecular Sciences. 20. PMID 31835809 DOI: 10.3390/Ijms20246253 |
0.317 |
|
| 2019 |
Zoicas I, Huber SE, Kalinichenko LS, Gulbins E, Müller CP, Kornhuber J. Ceramides affect alcohol consumption and depressive-like and anxiety-like behavior in a brain region- and ceramide species-specific way in male mice. Addiction Biology. e12847. PMID 31828921 DOI: 10.1111/Adb.12847 |
0.408 |
|
| 2019 |
Wigger D, Gulbins E, Kleuser B, Schumacher F. Monitoring the Sphingolipid Synthesis by Stable-Isotope Labeling and Liquid Chromatography-Mass Spectrometry. Frontiers in Cell and Developmental Biology. 7: 210. PMID 31632963 DOI: 10.3389/Fcell.2019.00210 |
0.303 |
|
| 2019 |
Kalinichenko LS, Mühle C, Eulenburg V, Praetner M, Reichel M, Gulbins E, Kornhuber J, Müller CP. Enhanced Alcohol Preference and Anxiolytic Alcohol Effects in Niemann-Pick Disease Model in Mice. Frontiers in Neurology. 10: 731. PMID 31333574 DOI: 10.3389/Fneur.2019.00731 |
0.41 |
|
| 2019 |
Mühle C, Wagner CJ, Färber K, Richter-Schmidinger T, Gulbins E, Lenz B, Kornhuber J. Secretory Acid Sphingomyelinase in the Serum of Medicated Patients Predicts the Prospective Course of Depression. Journal of Clinical Medicine. 8. PMID 31200571 DOI: 10.3390/Jcm8060846 |
0.431 |
|
| 2019 |
Baduva K, Büchter L, Kreyenkamp K, Westphal L, Wilker B, Kohnen M, Schuchman EH, Edwards MJ, Becker KA, Gulbins E, Carpinteiro A. Signalling Effects Induced by Acid Ceramidase in Human Epithelial Or Leukemic Cell Lines. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 52: 1092-1102. PMID 30977990 DOI: 10.33594/000000074 |
0.344 |
|
| 2019 |
Li C, Wang A, Wu Y, Gulbins E, Grassmé H, Zhao Z. Acid Sphingomyelinase-Ceramide System in Bacterial Infections. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 52: 280-301. PMID 30816675 DOI: 10.33594/000000021 |
0.356 |
|
| 2019 |
Kalinichenko LS, Hammad L, Reichel M, Kohl Z, Gulbins E, Kornhuber J, Müller CP. Acid sphingomyelinase controls dopamine activity and responses to appetitive stimuli in mice. Brain Research Bulletin. 146: 310-319. PMID 30716394 DOI: 10.1016/J.Brainresbull.2019.01.026 |
0.418 |
|
| 2019 |
Bodas M, Pehote G, Silverberg D, Gulbins E, Vij N. Autophagy augmentation alleviates cigarette smoke-induced CFTR-dysfunction, ceramide-accumulation and COPD-emphysema pathogenesis. Free Radical Biology & Medicine. 131: 81-97. PMID 30500419 DOI: 10.1016/J.Freeradbiomed.2018.11.023 |
0.362 |
|
| 2019 |
Kalinichenko L, Wang A, Roesel N, Muehle C, Lenz B, Gulbins E, Silva MAdS, Kornhuber J, Huston JP, Mueller CP. Ceramide system contributes to learning and memory Ibro Reports. 6: S76-S77. DOI: 10.1016/J.Ibror.2019.07.251 |
0.346 |
|
| 2018 |
Gulbins A, Schumacher F, Becker KA, Wilker B, Soddemann M, Boldrin F, Müller CP, Edwards MJ, Goodman M, Caldwell CC, Kleuser B, Kornhuber J, Szabo I, Gulbins E. Antidepressants regulate autophagy by targeting acid sphingomyelinase. Molecular Psychiatry. 23: 2251. PMID 30552418 DOI: 10.1038/S41380-018-0319-7 |
0.427 |
|
| 2018 |
Mühle C, Weinland C, Gulbins E, Lenz B, Kornhuber J. Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls. International Journal of Molecular Sciences. 19. PMID 30551571 DOI: 10.3390/Ijms19124028 |
0.431 |
|
| 2018 |
Wu Y, Li C, Riehle A, Pollmeier B, Gulbins E, Grassmé H. Mycobacterial Infection is Promoted by Neutral Sphingomyelinase 2 Regulating a Signaling Cascade Leading to Activation of β1-Integrin. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 51: 1815-1829. PMID 30504725 DOI: 10.1159/000495683 |
0.301 |
|
| 2018 |
Park MH, Lee JY, Park KH, Jung IK, Kim KT, Lee YS, Ryu HH, Jeong Y, Kang M, Schwaninger M, Gulbins E, Reichel M, Kornhuber J, Yamaguchi T, Kim HJ, et al. Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM. Neuron. 100: 762. PMID 30408445 DOI: 10.1016/J.Neuron.2018.10.038 |
0.375 |
|
| 2018 |
Reichel M, Rhein C, Hofmann LM, Monti J, Japtok L, Langgartner D, Füchsl AM, Kleuser B, Gulbins E, Hellerbrand C, Reber SO, Kornhuber J. Chronic Psychosocial Stress in Mice Is Associated With Increased Acid Sphingomyelinase Activity in Liver and Serum and With Hepatic C16:0-Ceramide Accumulation. Frontiers in Psychiatry. 9: 496. PMID 30386262 DOI: 10.3389/Fpsyt.2018.00496 |
0.428 |
|
| 2018 |
Park MH, Lee JY, Park KH, Jung IK, Kim KT, Lee YS, Ryu HH, Jeong Y, Kang M, Schwaninger M, Gulbins E, Reichel M, Kornhuber J, Yamaguchi T, Kim HJ, et al. Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM. Neuron. PMID 30269989 DOI: 10.1016/J.Neuron.2018.09.010 |
0.425 |
|
| 2018 |
Rhein C, Löber S, Gmeiner P, Gulbins E, Tripal P, Kornhuber J. Derivatization of common antidepressant drugs increases inhibition of acid sphingomyelinase and reduces induction of phospholipidosis. Journal of Neural Transmission (Vienna, Austria : 1996). 125: 1837-1845. PMID 30191367 DOI: 10.1007/S00702-018-1923-Z |
0.45 |
|
| 2018 |
Gulbins A, Schumacher F, Becker KA, Wilker B, Soddemann M, Boldrin F, Müller CP, Edwards MJ, Goodman M, Caldwell CC, Kleuser B, Kornhuber J, Szabo I, Gulbins E. Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide. Molecular Psychiatry. PMID 30038230 DOI: 10.1038/S41380-018-0090-9 |
0.463 |
|
| 2018 |
Beckmann N, Kadow S, Schumacher F, Göthert JR, Kesper S, Draeger A, Schulz-Schaeffer WJ, Wang J, Becker JU, Kramer M, Kühn C, Kleuser B, Becker KA, Gulbins E. Pathological manifestations of Farber disease in a new mouse model. Biological Chemistry. PMID 29908121 DOI: 10.1515/Hsz-2018-0170 |
0.312 |
|
| 2018 |
Becker KA, Riethmüller J, Seitz AP, Gardner A, Boudreau R, Kamler M, Kleuser B, Schuchman E, Caldwell CC, Edwards MJ, Grassmé H, Brodlie M, Gulbins E. Sphingolipids as targets for inhalation treatment of cystic fibrosis. Advanced Drug Delivery Reviews. PMID 29698625 DOI: 10.1016/J.Addr.2018.04.015 |
0.367 |
|
| 2018 |
Kim Y, Abplanalp WA, Jung AD, Schuster RM, Lentsch AB, Gulbins E, Caldwell CC, Pritts TA. Endocytosis of Red Blood Cell Microparticles by Pulmonary Endothelial Cells is Mediated By Rab5. Shock (Augusta, Ga.). 49: 288-294. PMID 29438268 DOI: 10.1097/Shk.0000000000000995 |
0.327 |
|
| 2018 |
Kalinichenko LS, Gulbins E, Kornhuber J, Müller CP. The role of sphingolipids in psychoactive drug use and addiction. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 29322265 DOI: 10.1007/S00702-018-1840-1 |
0.418 |
|
| 2017 |
Becker KA, Fahsel B, Kemper H, Mayeres J, Li C, Wilker B, Keitsch S, Soddemann M, Sehl C, Kohnen M, Edwards MJ, Grassmé H, Caldwell CC, Seitz A, Fraunholz M, ... Gulbins E, et al. Staphylococcus aureus α-toxin disrupts endothelial tight junctions via acid sphingomyelinase and ceramide. Infection and Immunity. PMID 29084896 DOI: 10.1128/Iai.00606-17 |
0.334 |
|
| 2017 |
Venturini E, Leanza L, Azzolini M, Kadow S, Mattarei A, Weller M, Tabatabai G, Edwards MJ, Zoratti M, Paradisi C, Szabò I, Gulbins E, Becker KA. Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells. Neuro-Signals. 25: 26-38. PMID 28869943 DOI: 10.1159/000480643 |
0.305 |
|
| 2017 |
Li C, Wu Y, Orian-Rousseau V, Zhang Y, Gulbins E, Grassme H. Regulation of Staphylococcus aureus infection of macrophages by CD44, reactive oxygen species and acid sphingomyelinase. Antioxidants & Redox Signaling. PMID 28747072 DOI: 10.1089/Ars.2017.6994 |
0.306 |
|
| 2017 |
Schumacher F, Neuber C, Finke H, Nieschalke K, Baesler J, Gulbins E, Kleuser B. The sphingosine 1-phosphate breakdown product, (2)-hexadecenal, forms protein adducts and glutathione conjugates in vitro. Journal of Lipid Research. 58: 1648-1660. PMID 28588048 DOI: 10.1194/Jlr.M076562 |
0.308 |
|
| 2017 |
Leanza L, Romio M, Becker KA, Azzolini M, Trentin L, Managò A, Venturini E, Zaccagnino A, Mattarei A, Carraretto L, Urbani A, Kadow S, Biasutto L, Martini V, Severin F, ... ... Gulbins E, et al. Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo. Cancer Cell. 31: 516-531.e10. PMID 28399409 DOI: 10.1016/J.Ccell.2017.03.003 |
0.314 |
|
| 2017 |
Martin GE, Boudreau RM, Couch C, Becker KA, Edwards MJ, Caldwell CC, Gulbins E, Seitz A. Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic. Biochimie. PMID 28341550 DOI: 10.1016/J.Biochi.2017.03.014 |
0.326 |
|
| 2017 |
Rhein C, Reichel M, Kramer M, Rotter A, Lenz B, Mühle C, Gulbins E, Kornhuber J. Alternative splicing of SMPD1 coding for acid sphingomyelinase in major depression. Journal of Affective Disorders. 209: 10-15. PMID 27866044 DOI: 10.1016/J.Jad.2016.09.019 |
0.437 |
|
| 2016 |
Müller CP, Kalinichenko LS, Tiesel J, Witt M, Stöckl T, Sprenger E, Fuchser J, Beckmann J, Praetner M, Huber SE, Amato D, Mühle C, Büttner C, Ekici AB, Smaga I, ... ... Gulbins E, et al. Paradoxical antidepressant effects of alcohol are related to acid sphingomyelinase and its control of sphingolipid homeostasis. Acta Neuropathologica. PMID 28000031 DOI: 10.1007/S00401-016-1658-6 |
0.416 |
|
| 2016 |
Wang L, Chen Y, Li X, Zhang Y, Gulbins E, Zhang Y. Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation. Oncotarget. PMID 27689324 DOI: 10.18632/Oncotarget.12302 |
0.315 |
|
| 2016 |
Hollmann C, Werner S, Avota E, Reuter D, Japtok L, Kleuser B, Gulbins E, Becker KA, Schneider-Schaulies J, Beyersdorf N. Inhibition of Acid Sphingomyelinase Allows for Selective Targeting of CD4+ Conventional versus Foxp3+ Regulatory T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 27638864 DOI: 10.4049/Jimmunol.1600691 |
0.34 |
|
| 2016 |
Makdessi SA, Sweidan H, Schmid E, Weimar U, Gulbins E, Lang F. Quantitative Determination of Ceramide Molecular Species in Dendritic Cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 1608-1617. PMID 27627650 DOI: 10.1159/000447862 |
0.368 |
|
| 2016 |
Zoicas I, Reichel M, Gulbins E, Kornhuber J. Role of Acid Sphingomyelinase in the Regulation of Social Behavior and Memory. Plos One. 11: e0162498. PMID 27598773 DOI: 10.1371/Journal.Pone.0162498 |
0.404 |
|
| 2016 |
Zhou Y, Salker MS, Walker B, Münzer P, Borst O, Gawaz M, Gulbins E, Singh Y, Lang F. Acid Sphingomyelinase (ASM) is a Negative Regulator of Regulatory T Cell (Treg) Development. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 985-995. PMID 27512981 DOI: 10.1159/000447806 |
0.32 |
|
| 2016 |
Gulbins A, Grassmé H, Hoehn R, Kohnen M, Edwards MJ, Kornhuber J, Gulbins E. Role of Janus-Kinases in Major Depressive Disorder. Neuro-Signals. 24: 71-80. PMID 27487096 DOI: 10.1159/000442613 |
0.434 |
|
| 2016 |
Gulbins A, Grassmé H, Hoehn R, Wilker B, Soddemann M, Kohnen M, Edwards MJ, Kornhuber J, Gulbins E. Regulation of Neuronal Stem Cell Proliferation in the Hippocampus by Endothelial Ceramide. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 790-801. PMID 27475812 DOI: 10.1159/000447789 |
0.428 |
|
| 2016 |
Hoehn R, Monse M, Pohl E, Wranik S, Wilker B, Keitsch S, Soddemann M, Kornhuber J, Kohnen M, Edwards MJ, Grassmé H, Gulbins E. Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System. Neuro-Signals. 24: 48-58. PMID 27398923 DOI: 10.1159/000442611 |
0.447 |
|
| 2016 |
Hoehn RS, Jernigan PL, Chang AL, Edwards MJ, Caldwell CC, Gulbins E, Pritts TA. Acid Sphingomyelinase Inhibition Prevents Hemolysis During Erythrocyte Storage. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 331-340. PMID 27352097 DOI: 10.1159/000445627 |
0.307 |
|
| 2016 |
Schneider M, Levant B, Reichel M, Gulbins E, Kornhuber J, Müller CP. Lipids in psychiatric disorders and preventive medicine. Neuroscience and Biobehavioral Reviews. PMID 27317860 DOI: 10.1016/J.Neubiorev.2016.06.002 |
0.427 |
|
| 2016 |
Huston JP, Kornhuber J, Mühle C, Japtok L, Komorowski M, Mattern C, Reichel M, Gulbins E, Kleuser B, Topic B, De Souza Silva MA, Müller CP. A sphingolipid mechanism for behavioral extinction. Journal of Neurochemistry. PMID 26788861 DOI: 10.1111/Jnc.13537 |
0.428 |
|
| 2016 |
Carpinteiro A, Beckmann N, Seitz A, Hessler G, Wilker B, Soddemann M, Helfrich I, Edelmann B, Gulbins E, Becker KA. Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 38: 1-14. PMID 26741636 DOI: 10.1159/000438604 |
0.304 |
|
| 2016 |
Li C, Peng H, Japtok L, Seitz A, Riehle A, Wilker B, Soddemann M, Kleuser B, Edwards M, Lammas D, Zhang Y, Gulbins E, Grassme H. Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis. Frontiers in Bioscience (Elite Edition). 8: 311-25. PMID 26709664 DOI: 10.2741/E769 |
0.327 |
|
| 2015 |
Jernigan PL, Hoehn RS, Grassmé H, Edwards MJ, Müller CP, Kornhuber J, Gulbins E. Sphingolipids in Major Depression. Neuro-Signals. 23: 49-58. PMID 26684792 DOI: 10.1159/000442603 |
0.421 |
|
| 2015 |
Grassmé H, Jernigan PL, Hoehn RS, Wilker B, Soddemann M, Edwards MJ, Müller CP, Kornhuber J, Gulbins E. Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression. Neuro-Signals. 23: 84-92. PMID 26682751 DOI: 10.1159/000442606 |
0.441 |
|
| 2015 |
Managò A, Leanza L, Carraretto L, Sassi N, Grancara S, Quintana-Cabrera R, Trimarco V, Toninello A, Scorrano L, Trentin L, Semenzato G, Gulbins E, Zoratti M, Szabò I. Early effects of the antineoplastic agent salinomycin on mitochondrial function. Cell Death & Disease. 6: e1930. PMID 26492365 DOI: 10.1038/Cddis.2015.263 |
0.319 |
|
| 2015 |
Reichel M, Hönig S, Liebisch G, Lüth A, Kleuser B, Gulbins E, Schmitz G, Kornhuber J. Alterations of plasma glycerophospholipid and sphingolipid species in male alcohol-dependent patients. Biochimica Et Biophysica Acta. 1851: 1501-10. PMID 26291032 DOI: 10.1016/J.Bbalip.2015.08.005 |
0.377 |
|
| 2015 |
Gulbins E, Walter S, Becker KA, Halmer R, Liu Y, Reichel M, Edwards MJ, Müller CP, Fassbender K, Kornhuber J. A central role for the acid sphingomyelinase/ceramide system in neurogenesis and major depression. Journal of Neurochemistry. 134: 183-92. PMID 25925550 DOI: 10.1111/Jnc.13145 |
0.424 |
|
| 2015 |
Carpinteiro A, Becker KA, Japtok L, Hessler G, Keitsch S, Požgajovà M, Schmid KW, Adams C, Müller S, Kleuser B, Edwards MJ, Grassmé H, Helfrich I, Gulbins E. Regulation of hematogenous tumor metastasis by acid sphingomyelinase. Embo Molecular Medicine. 7: 714-34. PMID 25851537 DOI: 10.15252/Emmm.201404571 |
0.315 |
|
| 2015 |
Seitz AP, Grassmé H, Edwards MJ, Pewzner-Jung Y, Gulbins E. Ceramide and sphingosine in pulmonary infections. Biological Chemistry. 396: 611-20. PMID 25720061 DOI: 10.1515/Hsz-2014-0285 |
0.323 |
|
| 2015 |
Managò A, Becker KA, Carpinteiro A, Wilker B, Soddemann M, Seitz AP, Edwards MJ, Grassmé H, Szabò I, Gulbins E. Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase. Antioxidants & Redox Signaling. 22: 1097-110. PMID 25686490 DOI: 10.1089/Ars.2014.5979 |
0.333 |
|
| 2015 |
Lang E, Bissinger R, Gulbins E, Lang F. Ceramide in the regulation of eryptosis, the suicidal erythrocyte death. Apoptosis : An International Journal On Programmed Cell Death. 20: 758-67. PMID 25637185 DOI: 10.1007/S10495-015-1094-4 |
0.348 |
|
| 2015 |
Peng H, Li C, Kadow S, Henry BD, Steinmann J, Becker KA, Riehle A, Beckmann N, Wilker B, Li PL, Pritts T, Edwards MJ, Zhang Y, Gulbins E, Grassmé H. Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis. Journal of Molecular Medicine (Berlin, Germany). 93: 675-89. PMID 25616357 DOI: 10.1007/S00109-014-1246-Y |
0.314 |
|
| 2015 |
Müller CP, Reichel M, Mühle C, Rhein C, Gulbins E, Kornhuber J. Brain membrane lipids in major depression and anxiety disorders. Biochimica Et Biophysica Acta. 1851: 1052-1065. PMID 25542508 DOI: 10.1016/J.Bbalip.2014.12.014 |
0.457 |
|
| 2015 |
Chen Y, Li X, Boini KM, Pitzer AL, Gulbins E, Zhang Y, Li PL. Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis. Biochimica Et Biophysica Acta. 1853: 396-408. PMID 25450976 DOI: 10.1016/J.Bbamcr.2014.11.012 |
0.32 |
|
| 2015 |
Leanza L, Venturini E, Kadow S, Carpinteiro A, Gulbins E, Becker KA. Targeting a mitochondrial potassium channel to fight cancer. Cell Calcium. 58: 131-138. PMID 25443654 DOI: 10.1016/J.Ceca.2014.09.006 |
0.327 |
|
| 2015 |
Henry BD, Neill DR, Becker KA, Gore S, Bricio-Moreno L, Ziobro R, Edwards MJ, Mühlemann K, Steinmann J, Kleuser B, Japtok L, Luginbühl M, Wolfmeier H, Scherag A, Gulbins E, et al. Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice. Nature Biotechnology. 33: 81-8. PMID 25362245 DOI: 10.1038/Nbt.3037 |
0.308 |
|
| 2015 |
Pewzner-Jung Y, Tabazavareh ST, Grassmé H, Becker KA, Japtok L, Steinmann J, Joseph T, Lang S, Tümmler B, Schuchman EH, Lentsch AB, Kleuser B, Edwards MJ, Futerman AH, Gulbins E. 38 Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa Journal of Cystic Fibrosis. 14. DOI: 10.1016/S1569-1993(15)30215-0 |
0.318 |
|
| 2014 |
Beckmann N, Sharma D, Gulbins E, Becker KA, Edelmann B. Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons. Frontiers in Physiology. 5: 331. PMID 25228885 DOI: 10.3389/Fphys.2014.00331 |
0.353 |
|
| 2014 |
Pewzner-Jung Y, Tavakoli Tabazavareh S, Grassmé H, Becker KA, Japtok L, Steinmann J, Joseph T, Lang S, Tuemmler B, Schuchman EH, Lentsch AB, Kleuser B, Edwards MJ, Futerman AH, Gulbins E. Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa. Embo Molecular Medicine. 6: 1205-14. PMID 25085879 DOI: 10.15252/Emmm.201404075 |
0.318 |
|
| 2014 |
Reichel M, Richter-Schmidinger T, Mühle C, Rhein C, Alexopoulos P, Schwab SG, Gulbins E, Kornhuber J. The common acid sphingomyelinase polymorphism p.G508R is associated with self-reported allergy. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 34: 82-91. PMID 24977483 DOI: 10.1159/000362986 |
0.476 |
|
| 2014 |
Mühle C, Amova V, Biermann T, Bayerlein K, Richter-Schmidinger T, Kraus T, Reichel M, Gulbins E, Kornhuber J. Sex-dependent decrease of sphingomyelinase activity during alcohol withdrawal treatment. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 34: 71-81. PMID 24977482 DOI: 10.1159/000362985 |
0.418 |
|
| 2014 |
Grassmé H, Carpinteiro A, Edwards MJ, Gulbins E, Becker KA. Regulation of the inflammasome by ceramide in cystic fibrosis lungs. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 34: 45-55. PMID 24977480 DOI: 10.1159/000362983 |
0.333 |
|
| 2014 |
Simonis A, Hebling S, Gulbins E, Schneider-Schaulies S, Schubert-Unkmeir A. Differential activation of acid sphingomyelinase and ceramide release determines invasiveness of Neisseria meningitidis into brain endothelial cells. Plos Pathogens. 10. PMID 24945304 DOI: 10.1371/Journal.Ppat.1004160 |
0.333 |
|
| 2014 |
Kornhuber J, Müller CP, Becker KA, Reichel M, Gulbins E. The ceramide system as a novel antidepressant target. Trends in Pharmacological Sciences. 35: 293-304. PMID 24793541 DOI: 10.1016/J.Tips.2014.04.003 |
0.432 |
|
| 2014 |
Li X, Zhang Y, Xia M, Gulbins E, Boini KM, Li PL. Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis. Plos One. 9: e87552. PMID 24475307 DOI: 10.1371/Journal.Pone.0087552 |
0.32 |
|
| 2014 |
Yang W, Schmid E, Nurbaeva MK, Szteyn K, Leibrock C, Yan J, Schaller M, Gulbins E, Shumilina E, Lang F. Role of acid sphingomyelinase in the regulation of mast cell function. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 44: 79-90. PMID 24164338 DOI: 10.1111/Cea.12229 |
0.319 |
|
| 2014 |
Szabò I, Leanza L, Managò A, Frezzato F, Becker K, Trentin L, Semenzato G, Gulbins E, Zoratti M. Inhibition of a Mitochondrial Potassium Channel as a New Therapeutic Strategy for Chronic Lymphocytic Leukemia Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.052 |
0.34 |
|
| 2013 |
Xu M, Li XX, Xiong J, Xia M, Gulbins E, Zhang Y, Li PL. Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes. Biochimica Et Biophysica Acta. 1833: 3228-36. PMID 24095928 DOI: 10.1016/J.Bbamcr.2013.09.015 |
0.314 |
|
| 2013 |
Gulbins E, Palmada M, Reichel M, Lüth A, Böhmer C, Amato D, Müller CP, Tischbirek CH, Groemer TW, Tabatabai G, Becker KA, Tripal P, Staedtler S, Ackermann TF, van Brederode J, et al. Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs. Nature Medicine. 19: 934-8. PMID 23770692 DOI: 10.1038/Nm.3214 |
0.461 |
|
| 2013 |
Gramatzki D, Herrmann C, Happold C, Becker KA, Gulbins E, Weller M, Tabatabai G. Glioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway. Plos One. 8: e63527. PMID 23667632 DOI: 10.1371/Journal.Pone.0063527 |
0.319 |
|
| 2013 |
Mühle C, Huttner HB, Walter S, Reichel M, Canneva F, Lewczuk P, Gulbins E, Kornhuber J. Characterization of acid sphingomyelinase activity in human cerebrospinal fluid. Plos One. 8: e62912. PMID 23658784 DOI: 10.1371/Journal.Pone.0062912 |
0.44 |
|
| 2013 |
Kornhuber J, Tripal P, Gulbins E, Muehlbacher M. Functional inhibitors of acid sphingomyelinase (FIASMAs). Handbook of Experimental Pharmacology. 169-86. PMID 23579455 DOI: 10.1007/978-3-7091-1368-4_9 |
0.459 |
|
| 2013 |
Mühle C, Reichel M, Gulbins E, Kornhuber J. Sphingolipids in psychiatric disorders and pain syndromes. Handbook of Experimental Pharmacology. 431-56. PMID 23563670 DOI: 10.1007/978-3-7091-1511-4_22 |
0.397 |
|
| 2013 |
Henry B, Möller C, Dimanche-Boitrel MT, Gulbins E, Becker KA. Targeting the ceramide system in cancer. Cancer Letters. 332: 286-94. PMID 21862212 DOI: 10.1016/J.Canlet.2011.07.010 |
0.302 |
|
| 2013 |
Reichel M, Palmada M, Lüth A, Böhmer C, Amato D, Müller CP, Tischbirek CH, Groemer TW, Tabatabai G, Becker KA, Tripal P, Staedtler S, Brederode Jv, Alzheimer C, Weller M, ... ... Gulbins E, et al. D.11 - The Acid Sphingomyelinase/Ceramide System As A New Pathway For Anti-Depressant Action Behavioural Pharmacology. 24. DOI: 10.1097/01.Fbp.0000434818.88064.6E |
0.419 |
|
| 2012 |
Li X, Gulbins E, Zhang Y. Role of kinase suppressor of ras-1 in lipopolysaccharide-induced acute lung injury. Cellular Physiology and Biochemistry. 30: 905-914. PMID 23221422 DOI: 10.1159/000341468 |
0.306 |
|
| 2012 |
Abed M, Towhid ST, Mia S, Pakladok T, Alesutan I, Borst O, Gawaz M, Gulbins E, Lang F. Sphingomyelinase-induced adhesion of eryptotic erythrocytes to endothelial cells. American Journal of Physiology-Cell Physiology. 303. PMID 22954799 DOI: 10.1152/Ajpcell.00239.2012 |
0.307 |
|
| 2012 |
Li X, Gulbins E, Zhang Y. Oxidative Stress Triggers Ca2+-Dependent Lysosome Trafficking And Activation Of Acid Sphingomyelinase Cellular Physiology and Biochemistry. 30: 815-826. PMID 22890197 DOI: 10.1159/000341460 |
0.365 |
|
| 2012 |
Leanza L, Zoratti M, Gulbins E, Szabo I. Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels. Current Medicinal Chemistry. 19: 5394-5404. PMID 22856664 DOI: 10.2174/092986712803833281 |
0.334 |
|
| 2012 |
Rhein C, Tripal P, Seebahn A, Konrad A, Kramer M, Nagel C, Kemper J, Bode J, Mühle C, Gulbins E, Reichel M, Becker CM, Kornhuber J. Functional implications of novel human acid sphingomyelinase splice variants. Plos One. 7: e35467. PMID 22558155 DOI: 10.1371/Journal.Pone.0035467 |
0.462 |
|
| 2012 |
Leanza L, Henry B, Sassi N, Zoratti M, Chandy KG, Gulbins E, Szabò I. Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells. Embo Molecular Medicine. 4: 577-93. PMID 22496117 DOI: 10.1002/Emmm.201200235 |
0.315 |
|
| 2012 |
Becker KA, Henry B, Ziobro R, Tümmler B, Gulbins E, Grassmé H. Role of CD95 in pulmonary inflammation and infection in cystic fibrosis. Journal of Molecular Medicine (Berlin, Germany). 90: 1011-23. PMID 22314624 DOI: 10.1007/S00109-012-0867-2 |
0.314 |
|
| 2011 |
Hörste MMz, Ströher E, Berchner-Pfannschmidt U, Schmitz-Spanke S, Pink M, Göthert JR, Fischer JW, Gulbins E, Eckstein AK. A novel mechanism involved in the pathogenesis of Graves ophthalmopathy (GO): clathrin is a possible targeting molecule for inhibiting local immune response in the orbit. The Journal of Clinical Endocrinology and Metabolism. 96. PMID 21917865 DOI: 10.1210/Jc.2011-1156 |
0.309 |
|
| 2011 |
Kornhuber J, Muehlbacher M, Trapp S, Pechmann S, Friedl A, Reichel M, Mühle C, Terfloth L, Groemer TW, Spitzer GM, Liedl KR, Gulbins E, Tripal P. Identification of novel functional inhibitors of acid sphingomyelinase. Plos One. 6: e23852. PMID 21909365 DOI: 10.1371/Journal.Pone.0023852 |
0.445 |
|
| 2011 |
Becker KA, Henry B, Ziobro R, Riethmüller J, Gulbins E. Lipids in cystic fibrosis. Expert Review of Respiratory Medicine. 5: 527-35. PMID 21859272 DOI: 10.1586/Ers.11.36 |
0.3 |
|
| 2011 |
Dimanche-Boitrel M, Rebillard A, Gulbins E. Ceramide in chemotherapy of tumors. Recent Patents On Anti-Cancer Drug Discovery. 6: 284-293. PMID 21762073 DOI: 10.2174/157489211796957838 |
0.332 |
|
| 2011 |
Lang F, Ullrich S, Gulbins E. Ceramide formation as a target in beta-cell survival and function. Expert Opinion On Therapeutic Targets. 15: 1061-1071. PMID 21635197 DOI: 10.1517/14728222.2011.588209 |
0.334 |
|
| 2011 |
Reichel M, Beck J, Mühle C, Rotter A, Bleich S, Gulbins E, Kornhuber J. Activity of secretory sphingomyelinase is increased in plasma of alcohol-dependent patients. Alcoholism, Clinical and Experimental Research. 35: 1852-9. PMID 21595704 DOI: 10.1111/J.1530-0277.2011.01529.X |
0.448 |
|
| 2011 |
Cheng Y, Gulbins E, Siemen D. Activation of the permeability transition pore by Bax via inhibition of the mitochondrial BK channel. Cellular Physiology and Biochemistry. 27: 191-200. PMID 21471707 DOI: 10.1159/000327944 |
0.301 |
|
| 2011 |
Avota E, Gulbins E, Schneider-Schaulies S. DC-SIGN Mediated Sphingomyelinase-Activation and Ceramide Generation Is Essential for Enhancement of Viral Uptake in Dendritic Cells Plos Pathogens. 7. PMID 21379338 DOI: 10.1371/Journal.Ppat.1001290 |
0.319 |
|
| 2011 |
Zhang Y, Li X, Carpinteiro A, Goettel JA, Soddemann M, Gulbins E. Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections. Nature Medicine. 17: 341-6. PMID 21297617 DOI: 10.1038/Nm.2296 |
0.315 |
|
| 2011 |
Szabo I, Soddemann M, Leanza L, Zoratti M, Gulbins E. Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax- and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis. Cell Death & Differentiation. 18: 427-438. PMID 20885444 DOI: 10.1038/Cdd.2010.112 |
0.31 |
|
| 2010 |
Becker KA, Tümmler B, Gulbins E, Grassmé H. Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death. Biochemical and Biophysical Research Communications. 403: 368-74. PMID 21078296 DOI: 10.1016/J.Bbrc.2010.11.038 |
0.337 |
|
| 2010 |
Perrotta C, Bizzozero L, Cazzato D, Morlacchi S, Assi E, Simbari F, Zhang Y, Gulbins E, Bassi MT, Rosa P, Clementi E. Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function Journal of Biological Chemistry. 285: 40240-40251. PMID 20956541 DOI: 10.1074/Jbc.M110.139287 |
0.382 |
|
| 2010 |
Grassmé H, Becker KA, Zhang Y, Gulbins E. CFTR-dependent susceptibility of the cystic fibrosis-host to Pseudomonas aeruginosa. International Journal of Medical Microbiology : Ijmm. 300: 578-83. PMID 20951085 DOI: 10.1016/J.Ijmm.2010.08.011 |
0.32 |
|
| 2010 |
Verdurmen WPR, Thanos M, Ruttekolk IR, Gulbins E, Brock R. Cationic cell-penetrating peptides induce ceramide formation via acid sphingomyelinase: implications for uptake. Journal of Controlled Release. 147: 171-179. PMID 20620184 DOI: 10.1016/J.Jconrel.2010.06.030 |
0.316 |
|
| 2010 |
Xuan NT, Shumilina E, Schmid E, Bhavsar SK, Rexhepaj R, Götz F, Gulbins E, Lang F. Role of acidic sphingomyelinase in thymol-mediated dendritic cell death Molecular Nutrition and Food Research. 54: 1833-1841. PMID 20603831 DOI: 10.1002/Mnfr.200900577 |
0.354 |
|
| 2010 |
Becker KA, Riethmüller J, Zhang Y, Gulbins E. The role of sphingolipids and ceramide in pulmonary inflammation in cystic fibrosis. The Open Respiratory Medicine Journal. 4: 39-47. PMID 20556203 DOI: 10.2174/1874306401004020039 |
0.318 |
|
| 2010 |
Becker KA, Grassmé H, Zhang Y, Gulbins E. Ceramide in Pseudomonas aeruginosa infections and cystic fibrosis. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 26: 57-66. PMID 20502005 DOI: 10.1159/000315106 |
0.328 |
|
| 2010 |
Lang F, Gulbins E, Lang PA, Zappulla D, Föller M. Ceramide in suicidal death of erythrocytes. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 26: 21-8. PMID 20502001 DOI: 10.1159/000315102 |
0.359 |
|
| 2010 |
Kornhuber J, Tripal P, Reichel M, Mühle C, Rhein C, Muehlbacher M, Groemer TW, Gulbins E. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 26: 9-20. PMID 20502000 DOI: 10.1159/000315101 |
0.428 |
|
| 2010 |
Zhang Y, Li X, Grassmé H, Döring G, Gulbins E. Alterations in Ceramide Concentration and pH Determine the Release of Reactive Oxygen Species by Cftr-Deficient Macrophages on Infection Journal of Immunology. 184: 5104-5111. PMID 20351190 DOI: 10.4049/Jimmunol.0902851 |
0.315 |
|
| 2010 |
Xuan NT, Shumilina E, Gulbins E, Gu S, Götz F, Lang F. Triggering of dendritic cell apoptosis by xanthohumol Molecular Nutrition and Food Research. 54: S214-S224. PMID 20333722 DOI: 10.1002/Mnfr.200900324 |
0.351 |
|
| 2010 |
Gulbins E, Sassi N, Grassmè H, Zoratti M, Szabò I. Role of Kv1.3 mitochondrial potassium channel in apoptotic signalling in lymphocytes. Biochimica Et Biophysica Acta. 1797: 1251-1259. PMID 20114030 DOI: 10.1016/J.Bbabio.2010.01.018 |
0.336 |
|
| 2010 |
Sassi N, Marchi UD, Fioretti B, Biasutto L, Gulbins E, Franciolini F, Szabò I, Zoratti M. An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1 Biochimica Et Biophysica Acta. 1797: 1260-1267. PMID 20036632 DOI: 10.1016/J.Bbabio.2009.12.015 |
0.314 |
|
| 2010 |
Reichel M, Greiner E, Richter-Schmidinger T, Yedibela O, Tripal P, Jacobi A, Bleich S, Gulbins E, Kornhuber J. Increased acid sphingomyelinase activity in peripheral blood cells of acutely intoxicated patients with alcohol dependence. Alcoholism, Clinical and Experimental Research. 34: 46-50. PMID 19860808 DOI: 10.1111/J.1530-0277.2009.01064.X |
0.436 |
|
| 2010 |
Becker KA, Riethmüller J, Lüth A, Döring G, Kleuser B, Gulbins E. Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis. American Journal of Respiratory Cell and Molecular Biology. 42: 716-24. PMID 19635928 DOI: 10.1165/Rcmb.2009-0174Oc |
0.334 |
|
| 2010 |
Becker KA, Riethmüller J, Zhang Y, Gulbins E. The Role of Sphingolipids and Ceramide in Pulmonary Inflammation in Cystic Fibrosis The Open Respiratory Medicine Journal. 4: 39-47. DOI: 10.2174/1874306401004010039 |
0.318 |
|
| 2009 |
Kornhuber J, Reichel M, Tripal P, Groemer TW, Henkel AW, Mühle C, Gulbins E. The role of ceramide in major depressive disorder. European Archives of Psychiatry and Clinical Neuroscience. 259: S199-204. PMID 19876679 DOI: 10.1007/S00406-009-0061-X |
0.463 |
|
| 2009 |
Gassert E, Avota E, Harms H, Krohne G, Gulbins E, Schneider-Schaulies S. Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression. Plos Pathogens. 5. PMID 19834551 DOI: 10.1371/Journal.Ppat.1000623 |
0.336 |
|
| 2009 |
Dumitru CA, Sandalcioglu IE, Wagner M, Weller M, Gulbins E. Lysosomal ceramide mediates gemcitabine-induced death of glioma cells. Journal of Molecular Medicine. 87: 1123-1132. PMID 19763526 DOI: 10.1007/S00109-009-0514-8 |
0.382 |
|
| 2009 |
Braun M, Föller M, Gulbins E, Lang F. Eryptosis triggered by bismuth Biometals. 22: 453-460. PMID 19048190 DOI: 10.1007/S10534-008-9180-5 |
0.314 |
|
| 2008 |
Lang F, Gulbins E, Lerche H, Huber SM, Kempe DS, Föller M. Eryptosis, a Window to Systemic Disease Cellular Physiology and Biochemistry. 22: 373-380. PMID 19088418 DOI: 10.1159/000185448 |
0.332 |
|
| 2008 |
Szabó I, Bock J, Grassmé H, Soddemann M, Wilker B, Lang F, Zoratti M, Gulbins E. Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 105: 14861-14866. PMID 18818304 DOI: 10.1073/Pnas.0804236105 |
0.303 |
|
| 2008 |
Grassmé H, Becker KA, Zhang Y, Gulbins E. Ceramide in bacterial infections and cystic fibrosis. Biological Chemistry. 389: 1371-9. PMID 18783339 DOI: 10.1515/Bc.2008.162 |
0.339 |
|
| 2008 |
Zhang Y, Li X, Carpinteiro A, Gulbins E. Acid Sphingomyelinase Amplifies Redox Signaling in Pseudomonas aeruginosa -Induced Macrophage Apoptosis Journal of Immunology. 181: 4247-4254. PMID 18768882 DOI: 10.4049/Jimmunol.181.6.4247 |
0.364 |
|
| 2008 |
Uhlig S, Gulbins E. Sphingolipids in the Lungs American Journal of Respiratory and Critical Care Medicine. 178: 1100-1114. PMID 18755926 DOI: 10.1164/Rccm.200804-595So |
0.328 |
|
| 2008 |
Becker KA, Gellhaus A, Winterhager E, Gulbins E. Ceramide-enriched membrane domains in infectious biology and development. Sub-Cellular Biochemistry. 49: 523-38. PMID 18751925 DOI: 10.1007/978-1-4020-8831-5_20 |
0.344 |
|
| 2008 |
Rebillard A, Rioux-Leclercq N, Muller C, Bellaud P, Jouan F, Meurette O, Jouan E, Vernhet L, Quément CL, Carpinteiro A, Schenck M, Lagadic-Gossmann D, Gulbins E, Dimanche-Boitrel MT. Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage. Oncogene. 27: 6590-6595. PMID 18679423 DOI: 10.1038/Onc.2008.257 |
0.322 |
|
| 2008 |
Hassan M, Alaoui A, Feyen O, Mirmohammadsadegh A, Essmann F, Tannapfel A, Gulbins E, Schulze-Osthoff K, Hengge UR. The BH3-only member Noxa causes apoptosis in melanoma cells by multiple pathways. Oncogene. 27: 4557-68. PMID 18408751 DOI: 10.1038/Onc.2008.90 |
0.323 |
|
| 2008 |
Möröy T, Zeng H, Jin J, Schmid KW, Carpinteiro A, Gulbins E. The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response. Immunobiology. 213: 341-52. PMID 18406379 DOI: 10.1016/J.Imbio.2007.11.004 |
0.308 |
|
| 2008 |
Teichgräber V, Ulrich M, Endlich N, Riethmüller J, Wilker B, De Oliveira-Munding CC, van Heeckeren AM, Barr ML, von Kürthy G, Schmid KW, Weller M, Tümmler B, Lang F, Grassme H, Döring G, ... Gulbins E, et al. Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nature Medicine. 14: 382-91. PMID 18376404 DOI: 10.1038/Nm1748 |
0.357 |
|
| 2008 |
Carpinteiro A, Dumitru C, Schenck M, Gulbins E. Ceramide-induced cell death in malignant cells. Cancer Letters. 264: 1-10. PMID 18353542 DOI: 10.1016/J.Canlet.2008.02.020 |
0.364 |
|
| 2008 |
Kornhuber J, Tripal P, Reichel M, Terfloth L, Bleich S, Wiltfang J, Gulbins E. Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of Medicinal Chemistry. 51: 219-37. PMID 18027916 DOI: 10.1021/Jm070524A |
0.433 |
|
| 2007 |
Lang F, Föller M, Lang K, Lang P, Ritter M, Vereninov A, Szabo I, Huber SM, Gulbins E. Cell volume regulatory ion channels in cell proliferation and cell death. Methods in Enzymology. 428: 209-25. PMID 17875419 DOI: 10.1016/S0076-6879(07)28011-5 |
0.32 |
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| 2007 |
Rebillard A, Tekpli X, Meurette O, Sergent O, LeMoigne-Muller G, Vernhet L, Gorria M, Chevanne M, Christmann M, Kaina B, Counillon L, Gulbins E, Lagadic-Gossmann D, Dimanche-Boitrel M. Cisplatin-Induced Apoptosis Involves Membrane Fluidification via Inhibition of NHE1 in Human Colon Cancer Cells Cancer Research. 67: 7865-7874. PMID 17699793 DOI: 10.1158/0008-5472.Can-07-0353 |
0.342 |
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| 2007 |
Dumitru CA, Zhang Y, Li X, Gulbins E. Ceramide: a novel player in reactive oxygen species-induced signaling? Antioxidants & Redox Signaling. 9: 1535-1540. PMID 17678446 DOI: 10.1089/Ars.2007.1692 |
0.317 |
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| 2007 |
Grammatikos G, Teichgräber V, Carpinteiro A, Trarbach T, Weller M, Hengge UR, Gulbins E. Overexpression of acid sphingomyelinase sensitizes glioma cells to chemotherapy. Antioxidants & Redox Signaling. 9: 1449-1456. PMID 17576160 DOI: 10.1089/Ars.2007.1673 |
0.315 |
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| 2007 |
Dumitru CA, Carpinteiro A, Trarbach T, Hengge UR, Gulbins E. Doxorubicin enhances TRAIL-induced cell death via ceramide-enriched membrane platforms Apoptosis. 12: 1533-1541. PMID 17520194 DOI: 10.1007/S10495-007-0081-9 |
0.33 |
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| 2007 |
Grassmé H, Riethmüller J, Gulbins E. Biological aspects of ceramide-enriched membrane domains. Progress in Lipid Research. 46: 161-170. PMID 17490747 DOI: 10.1016/J.Plipres.2007.03.002 |
0.33 |
|
| 2007 |
Schenck M, Carpinteiro A, Grassmé H, Lang F, Gulbins E. Ceramide: physiological and pathophysiological aspects. Archives of Biochemistry and Biophysics. 462: 171-175. PMID 17467652 DOI: 10.1016/J.Abb.2007.03.031 |
0.351 |
|
| 2007 |
Lang PA, Schenck M, Nicolay JP, Becker JU, Kempe DS, Lupescu A, Koka S, Eisele K, Klarl BA, Rübben H, Schmid KW, Mann K, Hildenbrand S, Hefter H, Huber SM, ... ... Gulbins E, et al. Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nature Medicine. 13: 164-70. PMID 17259995 DOI: 10.1038/Nm1539 |
0.309 |
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| 2007 |
Kempe DS, Akel A, Lang PA, Hermle T, Biswas R, Muresanu J, Friedrich B, Dreischer P, Wolz C, Schumacher U, Peschel A, Götz F, Döring G, Wieder T, Gulbins E, et al. Suicidal erythrocyte death in sepsis. Journal of Molecular Medicine (Berlin, Germany). 85: 273-81. PMID 17180345 DOI: 10.1007/S00109-006-0123-8 |
0.304 |
|
| 2007 |
Tripal P, Reichel M, Gulbins E, Kornhuber J. Prediction of functional inhibition of acid sphingomyelinase and acid ceramidase Pharmacopsychiatry. 40. DOI: 10.1055/S-2007-991891 |
0.409 |
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| 2007 |
Riethmüller J, Riehle A, Grassmé H, Gulbins E. Ceramide in Pseudomonas aeruginosa infections European Journal of Lipid Science and Technology. 109: 998-1002. DOI: 10.1002/Ejlt.200700045 |
0.358 |
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| 2006 |
Riethmüller J, Riehle A, Grassmé H, Gulbins E. Membrane rafts in host-pathogen interactions. Biochimica Et Biophysica Acta. 1758: 2139-2147. PMID 17094939 DOI: 10.1016/J.Bbamem.2006.07.017 |
0.333 |
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| 2006 |
Lang F, Shumilina E, Ritter M, Gulbins E, Vereninov A, Huber SM. Ion channels and cell volume in regulation of cell proliferation and apoptotic cell death. Contributions to Nephrology. 152: 142-160. PMID 17065810 DOI: 10.1159/000096321 |
0.311 |
|
| 2006 |
Lang PA, Huober J, Bachmann C, Kempe DS, Sobiesiak M, Akel A, Niemoeller OM, Dreischer P, Eisele K, Klarl BA, Gulbins E, Lang F, Wieder T. Stimulation of erythrocyte phosphatidylserine exposure by paclitaxel. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 18: 151-64. PMID 16914900 DOI: 10.1159/000095190 |
0.315 |
|
| 2006 |
Grassmé H, Jin J, Wilker B, Kürthy Gv, Wick W, Weller M, Möröy T, Gulbins E. Regulation of pulmonary Pseudomonas aeruginosa infection by the transcriptional repressor Gfi1. Cellular Microbiology. 8: 1096-1105. PMID 16819963 DOI: 10.1111/J.1462-5822.2006.00690.X |
0.346 |
|
| 2006 |
Dumitru CA, Gulbins E. TRAIL activates acid sphingomyelinase via a redox mechanism and releases ceramide to trigger apoptosis. Oncogene. 25: 5612-5625. PMID 16636669 DOI: 10.1038/Sj.Onc.1209568 |
0.346 |
|
| 2006 |
Dumitru CA, Dreschers S, Gulbins E. Rhinoviral infections activate p38MAP-kinases via membrane rafts and RhoA. Cellular Physiology and Biochemistry. 17: 159-166. PMID 16543732 DOI: 10.1159/000092077 |
0.308 |
|
| 2006 |
Kirschnek S, Gulbins E. Phospholipase A2 Functions in Pseudomonas aeruginosa- Induced Apoptosis Infection and Immunity. 74: 850-860. PMID 16428727 DOI: 10.1128/Iai.74.2.850-860.2006 |
0.364 |
|
| 2006 |
Gulbins E, Li PL. Physiological and pathophysiological aspects of ceramide. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R11-26. PMID 16352856 DOI: 10.1152/Ajpregu.00416.2005 |
0.347 |
|
| 2006 |
Zhang AY, Yi F, Zhang G, Gulbins E, Li PL. Lipid raft clustering and redox signaling platform formation in coronary arterial endothelial cells. Hypertension. 47: 74-80. PMID 16344372 DOI: 10.1161/01.Hyp.0000196727.53300.62 |
0.317 |
|
| 2005 |
Lang F, Föller M, Lang KS, Lang PA, Ritter M, Gulbins E, Vereninov A, Huber SM. Ion channels in cell proliferation and apoptotic cell death Journal of Membrane Biology. 205: 147-157. PMID 16362503 DOI: 10.1007/S00232-005-0780-5 |
0.325 |
|
| 2005 |
Kornhuber J, Medlin A, Bleich S, Jendrossek V, Henkel AW, Wiltfang J, Gulbins E. High activity of acid sphingomyelinase in major depression Journal of Neural Transmission. 112: 1583-1590. PMID 16245071 DOI: 10.1007/S00702-005-0374-5 |
0.452 |
|
| 2005 |
Bollinger CR, Teichgräber V, Gulbins E. Ceramide-enriched membrane domains. Biochimica Et Biophysica Acta. 1746: 284-294. PMID 16226325 DOI: 10.1016/J.Bbamcr.2005.09.001 |
0.328 |
|
| 2005 |
Grassmé H, Riehle A, Wilker B, Gulbins E. Rhinoviruses infect human epithelial cells via ceramide-enriched membrane platforms. Journal of Biological Chemistry. 280: 26256-26262. PMID 15888438 DOI: 10.1074/Jbc.M500835200 |
0.349 |
|
| 2005 |
Church LD, Hessler G, Goodall JE, Rider DA, Workman CJ, Vignali DA, Bacon PA, Gulbins E, Young SP. TNFR1-induced sphingomyelinase activation modulates TCR signaling by impairing store-operated Ca2+ influx. Journal of Leukocyte Biology. 78: 266-78. PMID 15817701 DOI: 10.1189/Jlb.1003456 |
0.306 |
|
| 2005 |
Wieder T, Lang PA, Lang KS, Kempe DS, Niemoeller OM, Duranton C, Gulbins E, Huber SM, Lang F. Studying mechanisms of eryptosis Cytotechnology. 49: 117-132. DOI: 10.1007/S10616-006-6335-5 |
0.332 |
|
| 2004 |
Lang F, Gulbins E, Szabo I, Lepple-Wienhues A, Huber SM, Duranton C, Lang KS, Lang PA, Wieder T. Cell volume and the regulation of apoptotic cell death. Journal of Molecular Recognition : Jmr. 17: 473-80. PMID 15362107 DOI: 10.1002/Jmr.705 |
0.352 |
|
| 2004 |
Scheel-Toellner D, Wang K, Craddock R, Webb PR, McGettrick HM, Assi LK, Parkes N, Clough LE, Gulbins E, Salmon M, Lord JM. Reactive oxygen species limit neutrophil life span by activating death receptor signaling Blood. 104: 2557-2564. PMID 15238425 DOI: 10.1182/Blood-2004-01-0191 |
0.336 |
|
| 2004 |
Gulbins E, Dreschers S, Wilker B, Grassmé H. Ceramide, membrane rafts and infections. Journal of Molecular Medicine. 82: 357-363. PMID 15069600 DOI: 10.1007/S00109-004-0539-Y |
0.342 |
|
| 2004 |
Göggel R, Winoto-Morbach S, Vielhaber G, Imai Y, Lindner K, Brade L, Brade H, Ehlers S, Slutsky AS, Schütze S, Gulbins E, Uhlig S. PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide Nature Medicine. 10: 155-160. PMID 14704790 DOI: 10.1038/Nm977 |
0.313 |
|
| 2003 |
Gulbins E, Kolesnick R. Raft ceramide in molecular medicine. Oncogene. 22: 7070-7. PMID 14557812 DOI: 10.1038/Sj.Onc.1207146 |
0.344 |
|
| 2003 |
Bock J, Szabó I, Gamper N, Adams C, Gulbins E. Ceramide inhibits the potassium channel Kv1.3 by the formation of membrane platforms Biochemical and Biophysical Research Communications. 305: 890-897. PMID 12767914 DOI: 10.1016/S0006-291X(03)00763-0 |
0.313 |
|
| 2003 |
Gulbins E. Regulation of death receptor signaling and apoptosis by ceramide Pharmacological Research. 47: 393-399. PMID 12676513 DOI: 10.1016/S1043-6618(03)00052-5 |
0.357 |
|
| 2003 |
Grassmé H, Jendrossek V, Riehle A, von Kürthy G, Berger J, Schwarz H, Weller M, Kolesnick R, Gulbins E. Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts. Nature Medicine. 9: 322-30. PMID 12563314 DOI: 10.1038/Nm823 |
0.352 |
|
| 2003 |
Gulbins E, Dreschers S, Bock J. Role of mitochondria in apoptosis. Experimental Physiology. 88: 85-90. PMID 12525857 DOI: 10.1113/Eph8802503 |
0.3 |
|
| 2002 |
Gulbins E, Grassmé H. Ceramide and cell death receptor clustering. Biochimica Et Biophysica Acta. 1585: 139-145. PMID 12531547 DOI: 10.1016/S1388-1981(02)00334-7 |
0.319 |
|
| 2002 |
Bock J, Szabo I, Jekle A, Gulbins E. Actinomycin D-induced apoptosis involves the potassium channel Kv1.3. Biochemical and Biophysical Research Communications. 295: 526-531. PMID 12150982 DOI: 10.1016/S0006-291X(02)00695-2 |
0.325 |
|
| 2002 |
Gulbins E, Kolesnick R. Acid sphingomyelinase-derived ceramide signaling in apoptosis. Sub-Cellular Biochemistry. 36: 229-44. PMID 12037984 DOI: 10.1007/0-306-47931-1_12 |
0.343 |
|
| 2001 |
Grassmé H, Jendrossek V, Gulbins E. Molecular mechanisms of bacteria induced apoptosis Apoptosis. 6: 441-445. PMID 11595833 DOI: 10.1023/A:1012485506972 |
0.328 |
|
| 2001 |
Esen M, Schreiner B, Jendrossek V, Lang F, Fassbender K, Grassmé H, Gulbins E. Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells Apoptosis. 6: 431-439. PMID 11595832 DOI: 10.1023/A:1012445925628 |
0.347 |
|
| 2001 |
Wagenknecht B, Roth W, Gulbins E, Wolburg H, Weller M. C2-ceramide signaling in glioma cells: synergistic enhancement of CD95-mediated, caspase-dependent apoptosis. Cell Death & Differentiation. 8: 595-602. PMID 11536010 DOI: 10.1038/Sj.Cdd.4400848 |
0.316 |
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| 2001 |
Röhn TA, Wagenknecht B, Roth W, Naumann U, Gulbins E, Krammer PH, Walczak H, Weller M. CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release Oncogene. 20: 4128-4137. PMID 11464279 DOI: 10.1038/Sj.Onc.1204534 |
0.306 |
|
| 2001 |
Cremesti A, Paris F, Grassmé H, Holler N, Tschopp J, Fuks Z, Gulbins E, Kolesnick R. Ceramide enables fas to cap and kill. The Journal of Biological Chemistry. 276: 23954-61. PMID 11287428 DOI: 10.1074/Jbc.M101866200 |
0.335 |
|
| 2001 |
Jendrossek V, Grassmé H, Mueller I, Lang F, Gulbins E. Pseudomonas aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases Infection and Immunity. 69: 2675-2683. PMID 11254634 DOI: 10.1128/Iai.69.4.2675-2683.2001 |
0.365 |
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| 2000 |
Lepple-Wienhues A, Szabò I, Wieland U, Heil L, Gulbins E, Lang F. Tyrosine Kinases Open Lymphocyte Chloride Channels Cellular Physiology and Biochemistry. 10: 307-312. PMID 11125210 DOI: 10.1159/000016363 |
0.329 |
|
| 2000 |
Paris F, Grassmé H, Cremesti A, Zager J, Fong Y, Haimovitz-Friedman A, Fuks Z, Gulbins E, Kolesnick R. Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes. The Journal of Biological Chemistry. 276: 8297-305. PMID 11096096 DOI: 10.1074/Jbc.M008732200 |
0.324 |
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| 2000 |
Uhlemann A, Müller C, Madlung J, Gulbins E, Lang F. Inhibition of CD95/Fas-induced DNA degradation by osmotic cell shrinkage. Cellular Physiology and Biochemistry. 10: 219-228. PMID 11093032 DOI: 10.1159/000016353 |
0.347 |
|
| 2000 |
Lang F, Madlung J, Bock J, Lükewille U, Kaltenbach S, Lang KS, Belka C, Wagner CA, Lang HJ, Gulbins E, Lepple-Wienhues A. Inhibition of Jurkat-T-lymphocyte Na+/H+-exchanger by CD95(Fas/Apo-1)-receptor stimulation. PflüGers Archiv: European Journal of Physiology. 440: 902-907. PMID 11041557 DOI: 10.1007/S004240000358 |
0.316 |
|
| 2000 |
Grassmé H, Kirschnek S, Riethmueller J, Riehle A, von Kürthy G, Lang F, Weller M, Gulbins E. CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa. Science (New York, N.Y.). 290: 527-30. PMID 11039936 DOI: 10.1126/Science.290.5491.527 |
0.306 |
|
| 2000 |
Hauck CR, Grassmé H, Bock J, Jendrossek V, Ferlinz K, Meyer TF, Gulbins E. Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosis of Neisseria gonorrhoeae. Febs Letters. 478: 260-266. PMID 10930579 DOI: 10.1016/S0014-5793(00)01851-2 |
0.343 |
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| 2000 |
Kirschnek S, Paris F, Weller M, Grassme H, Ferlinz K, Riehle A, Fuks Z, Kolesnick R, Gulbins E. CD95-mediated apoptosis in vivo involves acid sphingomyelinase. The Journal of Biological Chemistry. 275: 27316-23. PMID 10867001 DOI: 10.1074/Jbc.M002957200 |
0.326 |
|
| 2000 |
Lang F, Madlung J, Siemen D, Ellory C, Lepple-Wienhues A, Gulbins E. The involvement of caspases in the CD95(Fas/Apo-1)- but not swelling-induced cellular taurine release from Jurkat T-lymphocytes. PflüGers Archiv: European Journal of Physiology. 440: 93-99. PMID 10864002 DOI: 10.1007/S004240000247 |
0.315 |
|
| 2000 |
Walev I, Tappe D, Gulbins E, Bhakdi S. Streptolysin O-permeabilized granulocytes shed L-selectin concomitantly with ceramide generation via neutral sphingomyelinase. Journal of Leukocyte Biology. 68: 865-872. DOI: 10.1189/Jlb.68.6.865 |
0.319 |
|
| 1999 |
Lang F, Szabo I, Lepple-Wienhues A, Siemen D, Gulbins E. Physiology of Receptor-Mediated Lymphocyte Apoptosis Physiology. 14: 194-200. PMID 11390850 DOI: 10.1152/Physiologyonline.1999.14.5.194 |
0.317 |
|
| 1999 |
Lepple-Wienhues A, Belka C, Laun T, Jekle A, Walter B, Wieland U, Welz M, Heil L, Kun J, Busch G, Weller M, Bamberg M, Gulbins E, Lang F. Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids. Proceedings of the National Academy of Sciences of the United States of America. 96: 13795-800. PMID 10570152 DOI: 10.1073/Pnas.96.24.13795 |
0.313 |
|
| 1999 |
Belka C, Marini P, Lepple-Wienhues A, Budach W, Jekle A, Los MJ, Lang F, Schulze-Osthoff K, Gulbins E, Bamberg M. The tyrosine kinase lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation. Oncogene. 18: 4983-4992. PMID 10490833 DOI: 10.1038/Sj.Onc.1202878 |
0.307 |
|
| 1999 |
Lang F, Uhlemann AC, Lepple-Wienhues A, Szabo I, Siemen D, Nilius B, Gulbins E. Cell volume regulatory mechanisms in apoptotic cell death. Herz. 24: 232-235. PMID 10412647 DOI: 10.1007/Bf03044966 |
0.352 |
|
| 1999 |
Roller A, Bähr OR, Streffer J, Winter S, Heneka M, Deininger M, Meyermann R, Naumann U, Gulbins E, Weller M. Selective potentiation of drug cytotoxicity by NSAID in human glioma cells: the role of COX-1 and MRP. Biochemical and Biophysical Research Communications. 259: 600-605. PMID 10364464 DOI: 10.1006/Bbrc.1999.0825 |
0.303 |
|
| 1999 |
Wagenknecht B, Schulz JB, Gulbins E, Weller M. Crm-A, bcl-2 and NDGA inhibit CD95L-induced apoptosis of malignant glioma cells at the level of caspase 8 processing. Cell Death and Differentiation. 5: 894-900. PMID 10203695 DOI: 10.1038/Sj.Cdd.4400435 |
0.336 |
|
| 1999 |
Belka C, Marini P, Heinrich V, Budach W, Lepple-Wienhues A, Lang F, Gulbins E, Bamberg M. Taxane induced apoptosis occurs independently of AP-1 and acidic sphingomyelinase activation European Journal of Cancer. 35: S193. DOI: 10.1016/S0959-8049(99)81173-3 |
0.315 |
|
| 1998 |
Brenner B, Ferlinz K, Grassmé H, Weller M, Koppenhoefer U, Dichgans J, Sandhoff K, Lang F, Gulbins E. Fas/CD95/Apo-I activates the acidic sphingomyelinase via caspases. Cell Death and Differentiation. 5: 29-37. PMID 10200443 DOI: 10.1038/Sj.Cdd.4400307 |
0.338 |
|
| 1998 |
Lang F, Madlung J, Uhlemann AC, Risler T, Gulbins E. Cellular taurine release triggered by stimulation of the Fas(CD95) receptor in Jurkat lymphocytes PflüGers Archiv: European Journal of Physiology. 436: 377-383. PMID 9644219 DOI: 10.1007/S004240050646 |
0.314 |
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| 1998 |
Szabò I, Lepple-Wienhues A, Kaba KN, Zoratti M, Gulbins E, Lang F. Tyrosine Kinase-Dependent Activation of a Chloride Channel in CD95-Induced Apoptosis in T Lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 95: 6169-6174. PMID 9600936 DOI: 10.1073/Pnas.95.11.6169 |
0.34 |
|
| 1998 |
Lepple-Wienhues A, Szabò I, Laun T, Kaba NK, Gulbins E, Lang F. The tyrosine kinase p56lck mediates activation of swelling-induced chloride channels in lymphocytes. Journal of Cell Biology. 141: 281-286. PMID 9531565 DOI: 10.1083/Jcb.141.1.281 |
0.303 |
|
| 1997 |
Grassmé H, Gulbins E, Brenner B, Ferlinz K, Sandhoff K, Harzer K, Lang F, Meyer TF. Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells. Cell. 91: 605-15. PMID 9393854 DOI: 10.1016/S0092-8674(00)80448-1 |
0.324 |
|
| 1997 |
Koppenhoefer U, Brenner B, Lang F, Gulbins E. The CD40-ligand stimulates T-lymphocytes via the neutral sphingomyelinase: a novel function of the CD40-ligand as signalling molecule. Febs Letters. 414: 444-448. PMID 9315737 DOI: 10.1016/S0014-5793(97)01035-1 |
0.301 |
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| 1997 |
Gulbins E, Welsch J, Lepple-Wienhuis A, Heinle H, Lang F. Inhibition of Fas-Induced Apoptotic Cell Death by Osmotic Cell Shrinkage Biochemical and Biophysical Research Communications. 236: 517-521. PMID 9240472 DOI: 10.1006/Bbrc.1997.6775 |
0.35 |
|
| 1997 |
Wagenknecht B, Gulbins E, Lang F, Dichgans J, Weller M. Lipoxygenase inhibitors block CD95 ligand-mediated apoptosis of human malignant glioma cells. Febs Letters. 409: 17-23. PMID 9199495 DOI: 10.1016/S0014-5793(97)00468-7 |
0.325 |
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| 1997 |
Sammar M, Gulbins E, Hilbert K, Lang F, Altevogt P. Mouse CD24 as a signaling molecule for integrin-mediated cell binding: functional and physical association with src-kinases. Biochemical and Biophysical Research Communications. 234: 330-334. PMID 9177270 DOI: 10.1006/Bbrc.1997.6639 |
0.303 |
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| 1997 |
Wagenknecht B, Trepel M, Deimling Av, Grimmei C, Rollbrocke B, Hayash Y, Lang F, Dichgans J, Gulbins E, Weller M. p53 Accumulation Promotes Dephosphorylation and Proteolytic Cleavage of Retinoblastoma Protein in Human Malignant Glioma Cells Cellular Physiology and Biochemistry. 7: 304-311. DOI: 10.1159/000154888 |
0.321 |
|
| 1997 |
Szabò I, Gulbins E, Lang F. Regulation of Kv1.3 during Fas-Induced Apoptosis Cellular Physiology and Biochemistry. 7: 148-158. DOI: 10.1159/000154870 |
0.332 |
|
| 1996 |
Gulbins E, Brenner B, Schlottmann K, Welsch J, Heinle H, Koppenhoefer U, Linderkamp O, Coggeshall KM, Lang F. Fas-induced programmed cell death is mediated by a Ras-regulated O2- synthesis. Immunology. 89: 205-12. PMID 8943716 DOI: 10.1046/J.1365-2567.1996.D01-743.X |
0.308 |
|
| 1996 |
Schlottmann KE, Gulbins E, Lau SM, Coggeshall KM. Activation of Src-family tyrosine kinases during Fas-induced apoptosis. Journal of Leukocyte Biology. 60: 546-54. PMID 8864141 DOI: 10.1002/Jlb.60.4.546 |
0.33 |
|
| 1996 |
Szabò I, Gulbins E, Apfel H, Zhang X, Barth P, Busch AE, Schlottmann K, Pongs O, Lang F. Tyrosine phosphorylation-dependent suppression of a voltage-gated K+ channel in T lymphocytes upon Fas stimulation. The Journal of Biological Chemistry. 271: 20465-9. PMID 8702786 DOI: 10.1074/Jbc.271.34.20465 |
0.32 |
|
| 1993 |
Gulbins E, Coggeshall KM, Baier G, Katzav S, Burn P, Altman A. Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation. Science (New York, N.Y.). 260: 822-5. PMID 8484124 DOI: 10.1126/Science.8484124 |
0.304 |
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