Aubin Moutal, Ph.D - Publications

2014- University of Arizona, Tucson, AZ 
trafficking, synapse, pain, neurofibromatosis type 1

92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gomez K, Santiago U, Nelson TS, Allen HN, Calderon-Rivera A, Hestehave S, Rodríguez Palma EJ, Zhou Y, Duran P, Loya-Lopez S, Zhu E, Kumar U, Shields R, Koseli E, McKiver B, ... ... Moutal A, et al. A peptidomimetic modulator of the Ca2.2 N-type calcium channel for chronic pain. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305215120. PMID 37972067 DOI: 10.1073/pnas.2305215120  0.51
2023 Gomez K, Allen HN, Duran P, Loya-Lopez S, Calderon-Rivera A, Moutal A, Tang C, Nelson TS, Perez-Miller S, Khanna R. Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain. Pain. PMID 37862053 DOI: 10.1097/j.pain.0000000000003080  0.579
2023 Gomez K, Stratton HJ, Duran P, Loya S, Tang C, Calderon-Rivera A, François-Moutal L, Khanna M, Madura CL, Luo S, McKiver B, Choi E, Ran D, Boinon L, Perez-Miller S, ... ... Moutal A, et al. Identification and targeting of a unique Na1.7 domain driving chronic pain. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217800120. PMID 37498871 DOI: 10.1073/pnas.2217800120  0.482
2023 Gomez K, Duran P, Tonello R, Allen HN, Boinon L, Calderon-Rivera A, Loya-López S, Nelson TS, Ran D, Moutal A, Bunnett NW, Khanna R. Neuropilin-1 is essential for vascular endothelial growth factor A-mediated increase of sensory neuron activity and development of pain-like behaviors. Pain. PMID 37366599 DOI: 10.1097/j.pain.0000000000002970  0.588
2023 Wu XQ, Tan B, Du Y, Yang L, Hu TT, Ding YL, Qiu XY, Moutal A, Khanna R, Yu J, Chen Z. Glutamatergic and GABAergic neurons in the vLGN mediate the nociceptive effects of green and red light on neuropathic pain. Neurobiology of Disease. 106164. PMID 37217103 DOI: 10.1016/j.nbd.2023.106164  0.484
2022 Stratton HJ, Boinon L, Gomez K, Martin L, Duran P, Ran D, Zhou Y, Luo S, Perez-Miller S, Patek M, Ibrahim MM, Patwardhan A, Moutal A, Khanna R. Targeting the vascular endothelial growth factor A/neuropilin 1 axis for relief of neuropathic pain. Pain. PMID 36729125 DOI: 10.1097/j.pain.0000000000002850  0.546
2022 Jiang YP, Wang S, Lai WD, Wu XQ, Jin Y, Xu ZH, Moutal A, Khanna R, Park KD, Shan ZM, Wen CP, Yu J. Neuronal CRMP2 phosphorylation inhibition by the flavonoid, naringenin, contributes to the reversal of spinal sensitization and arthritic pain improvement. Arthritis Research & Therapy. 24: 277. PMID 36564853 DOI: 10.1186/s13075-022-02975-8  0.51
2022 Loya-López SI, Duran P, Ran D, Calderon-Rivera A, Gomez K, Moutal A, Khanna R. Cell specific regulation of NaV1.7 activity and trafficking in rat nodose ganglia neurons. Neurobiology of Pain (Cambridge, Mass.). 12: 100109. PMID 36531612 DOI: 10.1016/j.ynpai.2022.100109  0.584
2022 Duran P, Loya-López S, Ran D, Tang C, Calderon-Rivera A, Gomez K, Stratton HJ, Huang S, Xu YM, Wijeratne EMK, Perez-Miller S, Shan Z, Cai S, Gabrielsen AT, Dorame A, ... ... Moutal A, et al. The natural product Argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels. British Journal of Pharmacology. PMID 36245395 DOI: 10.1111/bph.15974  0.525
2022 Gomez K, Tang C, Tan B, Perez-Miller S, Ran D, Loya S, Calderon-Rivera A, Stratton HJ, Duran P, Masterson KA, Gabrielsen AT, Alsbiei O, Dorame A, Serafini M, Moutal A, et al. Stereospecific Effects of Benzimidazolonepiperidine Compounds on T-Type Ca Channels and Pain. Acs Chemical Neuroscience. PMID 35671441 DOI: 10.1021/acschemneuro.2c00256  0.516
2022 François-Moutal L, Scott DD, Ambrose AJ, Zerio CJ, Rodriguez-Sanchez M, Dissanayake K, May DG, Carlson JM, Barbieri E, Moutal A, Roux KJ, Shorter J, Khanna R, Barmada SJ, McGurk L, et al. Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology. Scientific Reports. 12: 8140. PMID 35581326 DOI: 10.1038/s41598-022-12191-8  0.398
2022 Ito H, Navratilova E, Vagnerova B, Watanabe M, Kopruszinski C, Moreira de Souza LH, Yue X, Ikegami D, Moutal A, Patwardhan A, Khanna R, Yamazaki M, Guerrero M, Rosen H, Roberts E, et al. Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance. Brain : a Journal of Neurology. PMID 35485490 DOI: 10.1093/brain/awac153  0.433
2022 Watanabe M, Kopruszinski CM, Moutal A, Ikegami D, Khanna R, Chen Y, Ross S, Mackenzie K, Stratton J, Dodick DW, Navratilova E, Porreca F. Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine. Brain : a Journal of Neurology. PMID 35325034 DOI: 10.1093/brain/awac104  0.455
2022 Boinon L, Yu J, Madura CL, Chefdeville A, Feinstein DL, Moutal A, Khanna R. Conditional knockout of CRMP2 in neurons, but not astrocytes, disrupts spinal nociceptive neurotransmission to control the initiation and maintenance of chronic neuropathic pain. Pain. 163: e368-e381. PMID 35029600 DOI: 10.1097/j.pain.0000000000002344  0.563
2021 Martin L, Ibrahim M, Gomez K, Yu J, Cai S, Chew LA, Bellampalli SS, Moutal A, Largent-Milnes T, Porreca F, Khanna R, Olivera BM, Patwardhan A. Conotoxin contulakin-G engages a neurotensin receptor 2 /R-type calcium channel (Cav2.3) pathway to mediate spinal antinociception. Pain. PMID 35050960 DOI: 10.1097/j.pain.0000000000002561  0.538
2021 Rivas CM, Schiff HV, Moutal A, Khanna R, Kiela PR, Dussor G, Price TJ, Vagner J, DeFea KA, Boitano S. Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression. Biochemical and Biophysical Research Communications. 591: 13-19. PMID 34990903 DOI: 10.1016/j.bbrc.2021.12.090  0.379
2021 Cai S, Moutal A, Yu J, Chew LA, Isensee J, Chawla R, Gomez K, Luo S, Zhou Y, Chefdeville A, Madura C, Perez-Miller S, Bellampalli SS, Dorame A, Scott DD, et al. Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents. Science Translational Medicine. 13: eabh1314. PMID 34757807 DOI: 10.1126/scitranslmed.abh1314  0.473
2021 Ikegami D, Navratilova E, Yue X, Moutal A, Kopruszinski CM, Khanna R, Patwardhan A, Dodick DW, Porreca F. A prolactin-dependent sexually dimorphic mechanism of migraine chronification. Cephalalgia : An International Journal of Headache. 3331024211039813. PMID 34510920 DOI: 10.1177/03331024211039813  0.361
2021 Martin LF, Moutal A, Cheng K, Washington SM, Calligaro H, Goel V, Kranz T, Largent-Milnes TM, Khanna R, Patwardhan A, Ibrahim MM. Green light antinociceptive and reversal of thermal and mechanical hypersensitivity effects rely on endogenous opioid system stimulation. The Journal of Pain. PMID 34157406 DOI: 10.1016/j.jpain.2021.05.006  0.468
2021 Zhang H, Lipinski AA, Liktor-Busa E, Smith AF, Moutal A, Khanna R, Langlais PR, Largent-Milnes TM, Vanderah TW. The Effects of Repeated Morphine Treatment on the Endogenous Cannabinoid System in the Ventral Tegmental Area. Frontiers in Pharmacology. 12: 632757. PMID 33953672 DOI: 10.3389/fphar.2021.632757  0.376
2021 Jeanne M, Demory H, Moutal A, Vuillaume ML, Blesson S, Thépault RA, Marouillat S, Halewa J, Maas SM, Motazacker MM, Mancini GMS, van Slegtenhorst MA, Andreou A, Cox H, Vogt J, et al. Missense variants in DPYSL5 cause a neurodevelopmental disorder with corpus callosum agenesis and cerebellar abnormalities. American Journal of Human Genetics. PMID 33894126 DOI: 10.1016/j.ajhg.2021.04.004  0.549
2021 Perez-Miller S, Patek M, Moutal A, Duran P, Cabel CR, Thorne CA, Campos SK, Khanna R. Novel Compounds Targeting Neuropilin Receptor 1 with Potential To Interfere with SARS-CoV-2 Virus Entry. Acs Chemical Neuroscience. PMID 33787218 DOI: 10.1021/acschemneuro.0c00619  0.46
2021 Gomez K, Ran D, Madura CL, Moutal A, Khanna R. Non-SUMOylated CRMP2 decreases Na1.7 currents via the endocytic proteins Numb, Nedd4-2 and Eps15. Molecular Brain. 14: 20. PMID 33478555 DOI: 10.1186/s13041-020-00714-1  0.536
2021 Cai S, Gomez K, Moutal A, Khanna R. Targeting T-type/CaV3.2 channels for chronic pain. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 33422652 DOI: 10.1016/j.trsl.2021.01.002  0.571
2021 Ran D, Gomez K, Moutal A, Patek M, Perez-Miller S, Khanna R. Comparison of quinazoline and benzoylpyrazoline chemotypes targeting the CaVα-β interaction as antagonists of the N-type CaV2.2 channel. Channels (Austin, Tex.). 15: 128-135. PMID 33416017 DOI: 10.1080/19336950.2020.1863595  0.508
2020 Dhanalakshmi C, Janakiraman U, Moutal A, Fukunaga K, Khanna R, Nelson MA. Evaluation of the effects of the T-type calcium channel enhancer SAK3 in a rat model of TAF1 deficiency. Neurobiology of Disease. 105224. PMID 33359140 DOI: 10.1016/j.nbd.2020.105224  0.472
2020 Moutal A, Martin LF, Boinon L, Gomez K, Ran D, Zhou Y, Stratton HJ, Cai S, Luo S, Gonzalez KB, Perez-Miller S, Patwardhan A, Ibrahim MM, Khanna R. SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia. Pain. PMID 33009246 DOI: 10.1097/j.pain.0000000000002097  0.478
2020 Perez-Miller S, Patek M, Moutal A, Cabel CR, Thorne CA, Campos SK, Khanna R. In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike protein. Biorxiv : the Preprint Server For Biology. PMID 32995772 DOI: 10.1101/2020.09.22.308783  0.466
2020 Krall RF, Moutal A, Phillips MB, Asraf H, Johnson JW, Khanna R, Hershfinkel M, Aizenman E, Tzounopoulos T. Synaptic zinc inhibition of NMDA receptors depends on the association of GluN2A with the zinc transporter ZnT1. Science Advances. 6. PMID 32937457 DOI: 10.1126/Sciadv.Abb1515  0.45
2020 Schulien AJ, Yeh CY, Orange BN, Pav OJ, Hopkins MP, Moutal A, Khanna R, Sun D, Justice JA, Aizenman E. Targeted disruption of Kv2.1-VAPA association provides neuroprotection against ischemic stroke in mice by declustering Kv2.1 channels. Science Advances. 6. PMID 32937450 DOI: 10.1126/Sciadv.Aaz8110  0.495
2020 Moutal A, Martin LF, Boinon L, Gomez K, Ran D, Zhou Y, Stratton HJ, Cai S, Luo S, Gonzalez KB, Perez-Miller S, Patwardhan A, Ibrahim MM, Khanna R. SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia. Biorxiv : the Preprint Server For Biology. PMID 32869019 DOI: 10.1101/2020.07.17.209288  0.478
2020 Quach TT, Moutal A, Khanna R, Deems NP, Duchemin AM, Barrientos RM. Collapsin Response Mediator Proteins: Novel Targets for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32804096 DOI: 10.3233/Jad-200721  0.477
2020 Gomez K, Vallecillo TGM, Moutal A, Perez-Miller S, Delgado-Lezama R, Felix R, Khanna R. The role of cyclin dependent kinase 5 (Cdk5) in neuropathic pain. Pain. PMID 32773603 DOI: 10.1097/J.Pain.0000000000002027  0.618
2020 Alles SRA, Gomez K, Moutal A, Khanna R. Putative roles of SLC7A5 (LAT1) transporter in pain. Neurobiology of Pain (Cambridge, Mass.). 8: 100050. PMID 32715162 DOI: 10.1016/J.Ynpai.2020.100050  0.611
2020 Khanna R, Moutal A, Perez-Miller S, Chefdeville A, Boinon L, Patek M. Druggability of CRMP2 for neurodegenerative diseases. Acs Chemical Neuroscience. PMID 32693579 DOI: 10.1021/Acschemneuro.0C00307  0.551
2020 Janakiraman U, Dhanalakshmi C, Yu J, Moutal A, Boinon L, Fukunaga K, Khanna R, Nelson MA. The investigation of the T-type calcium channel enhancer SAK3 in an animal model of TAF1 intellectual disability syndrome. Neurobiology of Disease. 143: 105006. PMID 32622085 DOI: 10.1016/J.Nbd.2020.105006  0.502
2020 Moutal A, Ji Y, Bellampalli SS, Khanna R. Differential expression of Cdk5-phosphorylated CRMP2 following a spared nerve injury. Molecular Brain. 13: 97. PMID 32571373 DOI: 10.1186/S13041-020-00633-1  0.595
2020 Moutal A, Cai S, Yu J, Stratton HJ, Chefdeville A, Gomez K, Ran D, Madura CL, Boinon L, Soto M, Zhou Y, Shan Z, Chew LA, Rodgers KE, Khanna R. Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific NaV1.7 regulation in the pathogenesis of chronic neuropathic pain. Pain. PMID 32569093 DOI: 10.1097/J.Pain.0000000000001951  0.604
2020 Cai S, Tuohy P, Ma C, Kitamura N, Gomez K, Zhou Y, Ran D, Bellampalli SS, Yu J, Luo S, Dorame A, Ngan Pham NY, Molnar G, Streicher JM, Patek M, ... ... Moutal A, et al. A modulator of the low-voltage activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies. Pain. PMID 32541387 DOI: 10.1097/J.Pain.0000000000001955  0.575
2020 Stratton H, Boinon L, Moutal A, Khanna R. Coordinating Synaptic Signaling with CRMP2. The International Journal of Biochemistry & Cell Biology. 105759. PMID 32437854 DOI: 10.1016/J.Biocel.2020.105759  0.506
2020 Zhou Y, Cai S, Gomez K, Wijeratne EMK, Ji Y, Bellampalli SS, Luo S, Moutal A, Gunatilaka AAL, Khanna R. 1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain. Molecular Brain. 13: 73. PMID 32393368 DOI: 10.1186/S13041-020-00616-2  0.608
2020 Chen Y, Moutal A, Navratilova E, Kopruszinski C, Yue X, Ikegami M, Chow M, Kanazawa I, Bellampalli SS, Xie J, Patwardhan A, Rice K, Fields H, Akopian A, Neugebauer V, et al. Erratum: The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females (Science Translational Medicine DOI: 10.1126/scitranslmed.aay7550) Science Translational Medicine. 12. PMID 32132219 DOI: 10.1126/Scitranslmed.Abb4549  0.461
2020 Chen Y, Moutal A, Navratilova E, Kopruszinski C, Yue X, Ikegami M, Chow M, Kanazawa I, Bellampalli SS, Xie J, Patwardhan A, Rice K, Fields H, Akopian A, Neugebauer V, et al. The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females. Science Translational Medicine. 12. PMID 32024801 DOI: 10.1126/Scitranslmed.Aay7550  0.52
2019 de Macedo FHP, Aires RD, Fonseca EG, Ferreira RCM, Machado DPD, Chen L, Zhang FX, Souza IA, Lemos VS, Romero TRL, Moutal A, Khanna R, Zamponi GW, Cruz JS. TNF-α mediated upregulation of Na1.7 currents in rat dorsal root ganglion neurons is independent of CRMP2 SUMOylation. Molecular Brain. 12: 117. PMID 31888677 DOI: 10.1186/S13041-019-0538-0  0.53
2019 Khanna R, Patwardhan A, Yang X, Li W, Cai S, Ji Y, Chew LA, Dorame A, Bellampalli SS, Schmoll RW, Gordon J, Moutal A, Vanderah TW, Porreca F, Ibrahim MM. Erratum to ‛Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light': The Journal of Pain 20 (2019) 1293-1306. The Journal of Pain : Official Journal of the American Pain Society. 20: 1509. PMID 31818395 DOI: 10.1016/J.Jpain.2019.11.012  0.526
2019 Moutal A, Kalinin S, Kowal K, Marangoni N, Dupree J, Lin SX, Lis K, Lisi L, Hensley K, Khanna R, Feinstein DL. Neuronal Conditional Knockout of Collapsin Response Mediator Protein 2 Ameliorates Disease Severity in a Mouse Model of Multiple Sclerosis. Asn Neuro. 11: 1759091419892090. PMID 31795726 DOI: 10.1177/1759091419892090  0.473
2019 Zhou Y, Cai S, Moutal A, Yu J, Gomez K, Madura CL, Shan Z, Ngan Pham NY, Serafini MJ, Dorame A, Scott DD, Francois-Moutal L, Perez-Miller S, Patek M, Khanna M, et al. The natural flavonoid Naringenin elicits analgesia through inhibition of NaV1.8 voltage-gated sodium channels. Acs Chemical Neuroscience. PMID 31697467 DOI: 10.1021/Acschemneuro.9B00547  0.591
2019 Moutal A, Shan Z, Miranda VG, François-Moutal L, Madura CL, Khanna M, Khanna R. Evaluation of edonerpic maleate as a CRMP2 inhibitor for pain relief. Channels (Austin, Tex.). 13: 498-504. PMID 31680630 DOI: 10.1080/19336950.2019.1684608  0.628
2019 Buchta WC, Moutal A, Hines B, Garcia-Keller C, Smith ACW, Kalivas P, Khanna R, Riegel AC. Dynamic CRMP2 Regulation of CaV2.2 in the Prefrontal Cortex Contributes to the Reinstatement of Cocaine Seeking. Molecular Neurobiology. PMID 31359322 DOI: 10.1007/S12035-019-01711-9  0.477
2019 Janakiraman U, Yu J, Moutal A, Raman DS, Boinon L, Batchelor SN, Annadurai A, Khanna R, Nelson MA. TAF1-gene editing alters the morphology and function of the cerebellum. Neurobiology of Disease. 104539. PMID 31344492 DOI: 10.1016/J.Nbd.2019.104539  0.506
2019 Yeh CY, Ye Z, Moutal A, Gaur S, Henton AM, Kouvaros S, Saloman JL, Hartnett-Scott KA, Tzounopoulos T, Khanna R, Aizenman E, Camacho CJ. Defining the Kv2.1-syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant. Proceedings of the National Academy of Sciences of the United States of America. PMID 31308225 DOI: 10.1073/Pnas.1903401116  0.538
2019 Khanna R, Moutal A, White KA, Chefdeville A, Negrao de Assis P, Cai S, Swier VJ, Bellampalli SS, Giunta MD, Darbro BW, Quelle DE, Sieren JC, Wallace MR, Rogers CS, Meyerholz DK, et al. Assessment of nociception and related quality of life measures in a porcine model of Neurofibromatosis type 1. Pain. PMID 31246731 DOI: 10.1097/J.Pain.0000000000001648  0.568
2019 Moutal A, Luo S, Largent-Milnes TM, Vanderah TW, Khanna R. Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain. Neurobiology of Pain (Cambridge, Mass.). 5. PMID 31080913 DOI: 10.1016/J.Ynpai.2018.07.003  0.602
2019 Khanna R, Patwardhan A, Yang X, Li W, Cai S, Ji Y, Chew LA, Dorame A, Bellampalli SS, Schmoll RW, Gordon J, Moutal A, Vanderah TW, Porreca F, Ibrahim MM. Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light. The Journal of Pain : Official Journal of the American Pain Society. PMID 31054915 DOI: 10.1016/J.Jpain.2019.04.008  0.548
2019 Cai S, Shan Z, Zhang Z, Moutal A, Khanna R. Activity of T-type calcium channels is independent of CRMP2 in sensory neurons. Channels (Austin, Tex.). 13: 147-152. PMID 31025580 DOI: 10.1080/19336950.2019.1608129  0.552
2019 Shan Z, Cai S, Yu J, Zhang Z, Vallecillo TGM, Serafini MJ, Thomas AM, Pham NYN, Bellampalli SS, Moutal A, Zhou Y, Xu GB, Xu YM, Luo S, Patek M, et al. Reversal of peripheral neuropathic pain by the small-molecule natural product physalin F via block of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels. Acs Chemical Neuroscience. PMID 30946560 DOI: 10.1021/Acschemneuro.9B00166  0.596
2019 Khanna R, Yu J, Yang X, Moutal A, Chefdeville A, Gokhale V, Shuja Z, Chew LA, Bellampalli SS, Luo S, François-Moutal L, Serafini MJ, Ha T, Perez-Miller S, Park KD, et al. Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy. Pain. PMID 30933958 DOI: 10.1097/J.Pain.0000000000001524  0.617
2019 Moutal A, White KA, Chefdeville A, Laufmann RN, Vitiello PF, Feinstein D, Weimer JM, Khanna R. Dysregulation of CRMP2 Post-Translational Modifications Drive Its Pathological Functions. Molecular Neurobiology. PMID 30915713 DOI: 10.1007/S12035-019-1568-4  0.543
2019 Moutal A, Dustrude ET, Largent-Milnes TM, Vanderah TW, Khanna M, Khanna R. Blocking CRMP2 SUMOylation reverses neuropathic pain. Molecular Psychiatry. 23: 2119-2121. PMID 28533518 DOI: 10.1038/Mp.2017.117  0.491
2018 Hurst SE, Liktor-Busa E, Moutal A, Parker S, Rice S, Szelinger S, Senner G, Hammer MF, Johnstone L, Ramsey K, Narayanan V, Perez-Miller S, Khanna M, Dahlin H, Lewis K, et al. A novel variant in affects gene expression and is associated with X-linked intellectual disability syndrome. Neuronal Signaling. 2: NS20180141. PMID 32714589 DOI: 10.1042/NS20180141  0.41
2018 Yu J, Moutal A, Dorame A, Bellampalli SS, Chefdeville A, Kanazawa I, Pham NYN, Park KD, Weimer JM, Khanna R. Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission. Molecular Neurobiology. PMID 30565051 DOI: 10.1007/S12035-018-1445-6  0.583
2018 Cai S, Bellampalli SS, Yu J, Li W, Ji Y, Wijeratne EMK, Dorame A, Luo S, Shan Z, Khanna M, Moutal A, Streicher JM, Gunatilaka AAL, Khanna R. (-)-Hardwickiic acid and Hautriwaic acid induce antinociception via blockade of tetrodotoxin-sensitive voltage-dependent sodium channels. Acs Chemical Neuroscience. PMID 30525440 DOI: 10.1021/Acschemneuro.8B00617  0.604
2018 Alberio L, Locarno A, Saponaro A, Romano E, Bercier V, Albadri S, Simeoni F, Moleri S, Pelucchi S, Porro A, Marcello E, Barsotti N, Kukovetz K, Boender AJ, Contestabile A, ... ... Moutal A, et al. A light-gated potassium channel for sustained neuronal inhibition. Nature Methods. PMID 30377377 DOI: 10.1038/S41592-018-0186-9  0.573
2018 Parker SS, Moutal A, Cai S, Chandrasekaran S, Roman MR, Koshy AA, Khanna R, Zinsmaier KE, Mouneimne G. High Fidelity Cryopreservation and Recovery of Primary Rodent Cortical Neurons. Eneuro. 5. PMID 30263951 DOI: 10.1523/ENEURO.0135-18.2018  0.415
2018 Bellampalli SS, Ji Y, Moutal A, Cai S, Wijeratne EMK, Gandini MA, Yu J, Chefdeville A, Dorame A, Chew LA, Madura CL, Luo S, Molnar G, Khanna M, Streicher JM, et al. Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels. Pain. PMID 30169422 DOI: 10.1097/J.Pain.0000000000001385  0.596
2018 Francois-Moutal L, Jahanbakhsh S, Nelson A, Ray D, Scott DD, Hennefarth M, Moutal A, Perez-Miller S, Ambrose AJ, Al-Shamari A, Coursodon P, Meechoovet B, Reiman R, Lyons E, Beilstein M, et al. A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B). Acs Chemical Biology. PMID 30141626 DOI: 10.1021/Acschembio.8B00745  0.42
2018 White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, ... ... Moutal A, et al. A porcine model of neurofibromatosis type 1 that mimics the human disease. Jci Insight. 3. PMID 29925695 DOI: 10.1172/Jci.Insight.120402  0.477
2018 François-Moutal L, Dustrude ET, Wang Y, Brustovetsky T, Dorame A, Ju W, Moutal A, Perez-Miller S, Brustovetsky N, Gokhale V, Khanna M, Khanna R. Inhibition of the Ubc9 E2 SUMO conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain. Pain. PMID 29847471 DOI: 10.1097/J.Pain.0000000000001294  0.61
2018 Moutal A, Sun L, Yang X, Li W, Cai S, Luo S, Khanna R. CRMP2 Neurofibromin Interface Drives NF1-related Pain. Neuroscience. PMID 29655575 DOI: 10.1016/J.Neuroscience.2018.04.002  0.571
2018 Parrilla-Carrero J, Buchta WC, Goswamee P, Culver O, McKendrick G, Harlan B, Moutal A, Penrod R, Khanna R, Kalivas P, Riegel AC. Restoration of Kv7 channel mediated inhibition reduces cued-reinstatement of cocaine seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29636392 DOI: 10.1523/Jneurosci.2767-17.2018  0.505
2018 Moutal A, Khanna R. Unconventional Signaling by Extracellular CRMP2: Possible Role as an Atypical Neurotransmitter? Neuroscience. 376: 224-226. PMID 29555038 DOI: 10.1016/J.Neuroscience.2018.02.025  0.44
2017 Naudet N, Moutal A, Vu HN, Chounlamountri N, Watrin C, Cavagna S, Malleval C, Benetollo C, Bardel C, Dronne MA, Honnorat J, Meissirel C, Besançon R. Transcriptional regulation of CRMP5 controls neurite outgrowth through Sox5. Cellular and Molecular Life Sciences : Cmls. PMID 28864883 DOI: 10.1007/S00018-017-2634-6  0.541
2017 Moutal A, Cai S, Luo S, Voisin R, Khanna R. CRMP2 is necessary for Neurofibromatosis type 1 related pain. Channels (Austin, Tex.). 0. PMID 28837387 DOI: 10.1080/19336950.2017.1370524  0.606
2017 Moutal A, Yang X, Li W, Gilbraith KB, Luo S, Cai S, François-Moutal L, Chew LA, Yeon SK, Bellampalli SS, Qu C, Xie JY, Ibrahim MM, Khanna M, Park KD, et al. CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide. Pain. PMID 28809766 DOI: 10.1097/J.Pain.0000000000001002  0.607
2017 Moutal A, Wang Y, Yang X, Ji Y, Luo S, Dorame A, Bellampalli SS, Chew LA, Cai S, Dustrude ET, Keener JE, Marty MT, Vanderah TW, Khanna R. Dissecting the role of the CRMP2-Neurofibromin complex on pain behaviors. Pain. PMID 28767512 DOI: 10.1097/J.Pain.0000000000001026  0.602
2017 Moutal A, Villa LS, Yeon SK, Householder KT, Park KD, Sirianni RW, Khanna R. CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation. Molecular Neurobiology. PMID 28660485 DOI: 10.1007/S12035-017-0653-9  0.484
2017 Sandweiss AJ, McIntosh MI, Moutal A, Davidson-Knapp R, Hu J, Giri AK, Yamamoto T, Hruby VJ, Khanna R, Largent-Milnes TM, Vanderah TW. Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential. Molecular Psychiatry. PMID 28485408 DOI: 10.1038/Mp.2017.102  0.548
2017 Yeh CY, Bulas AM, Moutal A, Saloman JL, Hartnett KA, Anderson CT, Tzounopoulos T, Sun D, Khanna R, Aizenman E. Targeting a Potassium Channel/Syntaxin Interaction Ameliorates Cell Death in Ischemic Stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28483976 DOI: 10.1523/Jneurosci.3811-16.2017  0.531
2017 Dustrude ET, Perez-Miller S, François-Moutal L, Moutal A, Khanna M, Khanna R. A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function. Channels (Austin, Tex.). 0. PMID 28277940 DOI: 10.1080/19336950.2017.1299838  0.489
2017 Moutal A, Li W, Wang Y, Ju W, Luo S, Cai S, François-Moutal L, Perez-Miller S, Hu J, Dustrude ET, Vanderah TW, Gokhale V, Khanna M, Khanna R. Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of CRMP2-derived peptides. British Journal of Pharmacology. PMID 28161890 DOI: 10.1111/Bph.13737  0.618
2017 Ibrahim MM, Patwardhan A, Gilbraith KB, Moutal A, Yang X, Chew LA, Largent-Milnes T, Malan TP, Vanderah TW, Porreca F, Khanna R. Long-lasting antinociceptive effects of green light in acute and chronic pain in rats. Pain. 158: 347-360. PMID 28092651 DOI: 10.1097/J.Pain.0000000000000767  0.567
2016 Dustrude ET, Moutal A, Yang X, Wang Y, Khanna M, Khanna R. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function. Proceedings of the National Academy of Sciences of the United States of America. PMID 27940916 DOI: 10.1073/Pnas.1610531113  0.596
2016 Moutal A, Eyde N, Telemi E, Park KD, Xie JY, Dodick DW, Porreca F, Khanna R. Efficacy of (S)-Lacosamide in preclinical models of cephalic pain. Pain Reports (Baltimore, Md.). 1. PMID 27917413 DOI: 10.1097/PR9.0000000000000565  0.516
2016 Xie JY, Chew LA, Yang X, Wang Y, Qu C, Wang Y, Federici LM, Fitz SD, Ripsch MS, Due MR, Moutal A, Khanna M, White FA, Vanderah TW, Johnson PL, et al. Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential. Pain. 157: 2124-2140. PMID 27537210 DOI: 10.1097/J.Pain.0000000000000628  0.595
2016 Moutal A, Dustrude ET, Khanna R. Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1. Molecular Neurobiology. PMID 27167129 DOI: 10.1007/S12035-016-9907-1  0.504
2016 Moutal A, Chew LA, Yang X, Wang Y, Yeon SK, Telemi E, Meroueh S, Park KD, Shrinivasan R, Gilbraith KB, Qu C, Xie JY, Patwardhan A, Vanderah TW, Khanna M, et al. (S)-Lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology. Pain. PMID 26967696 DOI: 10.1097/J.Pain.0000000000000555  0.626
2015 Moutal A, Honnorat J, Massoma P, Désormeaux P, Bertrand C, Malleval C, Watrin C, Chounlamountri N, Mayeur ME, Besançon R, Naudet N, Magadoux L, Khanna R, Ducray F, Meyronet D, et al. CRMP5 Controls Glioblastoma Cell Proliferation and Survival through Notch-Dependent Signaling. Cancer Research. 75: 3519-28. PMID 26122847 DOI: 10.1158/0008-5472.Can-14-0631  0.74
2015 Moutal A, François-Moutal L, Perez-Miller S, Cottier K, Chew LA, Yeon SK, Dai J, Park KD, Khanna M, Khanna R. (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5. Molecular Neurobiology. PMID 25846820 DOI: 10.1007/S12035-015-9141-2  0.507
2015 François-Moutal L, Wang Y, Moutal A, Cottier KE, Melemedjian OK, Yang X, Wang Y, Ju W, Largent-Milnes TM, Khanna M, Vanderah TW, Khanna R. A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Pain. 156: 1247-64. PMID 25782368 DOI: 10.1097/j.pain.0000000000000147  0.524
2015 Wang Y, Francois-Moutal L, Moutal A, Cottier K, Melemedjian O, Khanna M, Vanderah T, Khanna R. (399) A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses post-operative pain behaviors The Journal of Pain. 16: S75. DOI: 10.1016/J.Jpain.2015.01.318  0.503
2014 Moutal A, François-Moutal L, Brittain JM, Khanna M, Khanna R. Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides. Frontiers in Cellular Neuroscience. 8: 471. PMID 25674050 DOI: 10.3389/Fncel.2014.00471  0.488
2014 Wilson SM, Moutal A, Melemedjian OK, Wang Y, Ju W, François-Moutal L, Khanna M, Khanna R. The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth. Frontiers in Cellular Neuroscience. 8: 196. PMID 25104922 DOI: 10.3389/Fncel.2014.00196  0.533
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