Year |
Citation |
Score |
2020 |
Louis-Dit-Picard H, Kouranti I, Rafael C, Loisel-Ferreira I, Chavez-Canales M, Abdel Khalek W, Argaiz E, Baron S, Vacle S, Migeon T, Coleman R, Do Cruzeiro M, Hureaux M, Thurairajasingam N, Decramer S, et al. Mutations affecting the conserved acidic WNK1 motif cause inherited hyperkalemic hyperchloremic acidosis. The Journal of Clinical Investigation. PMID 32790646 DOI: 10.1172/Jci94171 |
0.439 |
|
2019 |
Murthy M, O'Shaughnessy KM. Modified HEK cells simulate DCT cells in their sensitivity and response to changes in extracellular K. Physiological Reports. 7: e14280. PMID 31762176 DOI: 10.14814/phy2.14280 |
0.518 |
|
2019 |
Sandilands AJ, O'Shaughnessy KM, Yasmin Y. 1-adrenoceptor polymorphisms and blood pressure: 49S variant increases plasma renin but not blood pressure in hypertensive patients. American Journal of Hypertension. PMID 30753253 DOI: 10.1093/Ajh/Hpz019 |
0.744 |
|
2018 |
Maskari RA, Hardege I, Cleary S, Figg N, Li Y, Siew K, Khir A, Yu Y, Liu P, Wilkinson I, O'Shaughnessy K, Yasmin. Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness. European Journal of Human Genetics : Ejhg. 26: 1648-1657. PMID 30089823 DOI: 10.1038/s41431-018-0226-z |
0.677 |
|
2018 |
Yasmin, Maskari RA, McEniery CM, Cleary SE, Li Y, Siew K, Figg NL, Khir AW, Cockcroft JR, Wilkinson IB, O'Shaughnessy KM. The matrix proteins aggrecan and fibulin-1 play a key role in determining aortic stiffness. Scientific Reports. 8: 8550. PMID 29867203 DOI: 10.1038/s41598-018-25851-5 |
0.709 |
|
2017 |
Hardege I, Long L, Al Maskari R, Figg N, O'Shaughnessy KM. Targeted disruption of the KCNJ5 gene in the female mouse lowers aldosterone levels. Clinical Science (London, England : 1979). PMID 29222092 DOI: 10.1042/Cs20171285 |
0.775 |
|
2017 |
Ware JS, Wain LV, Channavajjhala SK, Jackson VE, Edwards E, Lu R, Siew K, Jia W, Shrine N, Kinnear S, Jalland M, Henry AP, Clayton J, O'Shaughnessy KM, Tobin MD, et al. Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia. The Journal of Clinical Investigation. 127: 3367-3374. PMID 28783044 DOI: 10.1172/JCI89812 |
0.734 |
|
2016 |
Murthy M, Kurz T, O'Shaughnessy KM. WNK signalling pathways in blood pressure regulation. Cellular and Molecular Life Sciences : Cmls. PMID 27815594 DOI: 10.1007/s00018-016-2402-z |
0.581 |
|
2016 |
Al Maskari R, Yasmin, Cleary S, Figg N, Mehta S, Rassl D, Wilkinson I, O'Shaughnessy KM. A missense TGFB2 variant p.(Arg320Cys) causes a paradoxical and striking increase in aortic TGFB1/2 expression. European Journal of Human Genetics : Ejhg. PMID 27782106 DOI: 10.1038/Ejhg.2016.143 |
0.733 |
|
2016 |
Murthy M, Kurz T, O'Shaughnessy KM. ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403-459 mutation. Physiological Reports. 4. PMID 27378813 DOI: 10.14814/Phy2.12850 |
0.649 |
|
2015 |
Hardege I, Xu S, Gordon RD, Thompson AJ, Figg N, Stowasser M, Murrell-Lagnado R, O'Shaughnessy KM. Novel insertion mutation in KCNJ5 channel produces constitutive aldosterone release from H295R cells. Molecular Endocrinology (Baltimore, Md.). me20151195. PMID 26340408 DOI: 10.1210/Me.2015-1195 |
0.738 |
|
2015 |
Schumacher FR, Siew K, Zhang J, Johnson C, Wood N, Cleary SE, Al Maskari RS, Ferryman JT, Hardege I, Yasmin, Figg NL, Enchev R, Knebel A, O'Shaughnessy KM, Kurz T. Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia. Embo Molecular Medicine. 7: 1285-306. PMID 26286618 DOI: 10.15252/emmm.201505444 |
0.754 |
|
2015 |
Zhang J, Siew K, Macartney T, O'Shaughnessy KM, Alessi DR. Critical role of the SPAK protein kinase CCT domain in controlling blood pressure. Human Molecular Genetics. 24: 4545-58. PMID 25994507 DOI: 10.1093/hmg/ddv185 |
0.745 |
|
2015 |
Barber J, McKeever TM, McDowell SE, Clayton JA, Ferner RE, Gordon RD, Stowasser M, O'Shaughnessy KM, Hall IP, Glover M. A systematic review and meta-analysis of thiazide-induced hyponatraemia: time to reconsider electrolyte monitoring regimens after thiazide initiation? British Journal of Clinical Pharmacology. 79: 566-77. PMID 25139696 DOI: 10.1111/Bcp.12499 |
0.521 |
|
2014 |
O'Shaughnessy KM. Gordon Syndrome: a continuing story. Pediatric Nephrology (Berlin, Germany). PMID 25503323 DOI: 10.1007/s00467-014-2956-7 |
0.3 |
|
2014 |
Murthy M, Xu S, Massimo G, Wolley M, Gordon RD, Stowasser M, O'Shaughnessy KM. Role for germline mutations and a rare coding single nucleotide polymorphism within the KCNJ5 potassium channel in a large cohort of sporadic cases of primary aldosteronism. Hypertension. 63: 783-9. PMID 24420545 DOI: 10.1161/Hypertensionaha.113.02234 |
0.626 |
|
2014 |
Glover M, Ware JS, Henry A, Wolley M, Walsh R, Wain LV, Xu S, Van't Hoff WG, Tobin MD, Hall IP, Cook S, Gordon RD, Stowasser M, O'Shaughnessy KM. Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome). Clinical Science (London, England : 1979). 126: 721-6. PMID 24266877 DOI: 10.1042/Cs20130326 |
0.586 |
|
2014 |
Siew K, de los Heros P, Alessi DR, O'Shaughnessy KM. Erratum: PD.1. Blood pressure maintenance in MO25β has no physiological role in electrolyte homeostasis or systemic blood pressure maintenance in the mouse Journal of Human Hypertension. 28: 342-342. DOI: 10.1038/Jhh.2013.120 |
0.64 |
|
2014 |
Maskari RA, Cleary S, Li Y, Khir A, Mitchell G, Wilkinson I, O'Shaughnessy K, Yasmin. Genetic variations on chromosome 14 influence BCL11B gene expression levels and aortic stiffness Artery Research. 8: 126-127. DOI: 10.1016/J.Artres.2014.09.070 |
0.718 |
|
2014 |
Yasmin, McEniery C, Cleary S, Lam B, Kuper H, Endo Y, Kinra S, Chen D, Chandak G, Deanfield J, Lawlor D, Cockcroft J, Wilkinson I, O'Shaughnessy K. Genome wide association scan identifies loci for arterial stiffness in young healthy adults Artery Research. 8: 122. DOI: 10.1016/J.Artres.2014.09.050 |
0.693 |
|
2013 |
Glover M, O'Shaughnessy KM. Molecular insights from dysregulation of the thiazide-sensitive WNK/SPAK/NCC pathway in the kidney: Gordon syndrome and thiazide-induced hyponatraemia. Clinical and Experimental Pharmacology & Physiology. 40: 876-84. PMID 23683032 DOI: 10.1111/1440-1681.12115 |
0.631 |
|
2013 |
Siew K, O'Shaughnessy KM. Extrarenal roles of the with-no-lysine[K] kinases (WNKs). Clinical and Experimental Pharmacology & Physiology. 40: 885-94. PMID 23662678 DOI: 10.1111/1440-1681.12108 |
0.69 |
|
2012 |
Murthy M, Azizan EA, Brown MJ, O'Shaughnessy KM. Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma. Journal of Hypertension. 30: 1827-33. PMID 22743686 DOI: 10.1097/HJH.0b013e328356139f |
0.56 |
|
2012 |
Azizan EA, Murthy M, Stowasser M, Gordon R, Kowalski B, Xu S, Brown MJ, O'Shaughnessy KM. Somatic mutations affecting the selectivity filter of KCNJ5 are frequent in 2 large unselected collections of adrenal aldosteronomas. Hypertension. 59: 587-91. PMID 22252394 DOI: 10.1161/Hypertensionaha.111.186239 |
0.587 |
|
2012 |
Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Yasmin, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, et al. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circulation. Cardiovascular Genetics. 5: 81-90. PMID 22068335 DOI: 10.1161/Circgenetics.111.959817 |
0.365 |
|
2012 |
Gordon R, Stowasser M, Xu S, Wolley M, Glover M, O'Shaughnessy K. Relevance of plasma aldosterone responsiveness to upright posture, hybrid steroids and histology of Aldosterone-Producing Adenomas (APAs) to the finding of KCNJ5 mutations in some APAs American Journal of Hypertension. 25: 1315-1315. DOI: 10.1038/Ajh.2012.134 |
0.554 |
|
2011 |
Glover M, Zuber AM, O'Shaughnessy KM. Hypertension, dietary salt intake, and the role of the thiazide-sensitive sodium chloride transporter NCCT. Cardiovascular Therapeutics. 29: 68-76. PMID 21167012 DOI: 10.1111/J.1755-5922.2010.00180.X |
0.574 |
|
2011 |
Glover M, O'shaughnessy KM. SPAK and WNK kinases: a new target for blood pressure treatment? Current Opinion in Nephrology and Hypertension. 20: 16-22. PMID 21088576 DOI: 10.1097/Mnh.0B013E32834132Bc |
0.597 |
|
2010 |
Glover M, Sweeny C, Davis B, O'Shaughnessy KM. A Single Amino Acid Substitution Makes WNK4 Susceptible to SB 203580 and SB 202190. The Open Medicinal Chemistry Journal. 4: 57-61. PMID 21249167 DOI: 10.2174/1874104501004010057 |
0.544 |
|
2010 |
Glover M, Mercier Zuber A, Figg N, O'Shaughnessy KM. The activity of the thiazide-sensitive Na(+)-Cl(-) cotransporter is regulated by protein phosphatase PP4. Canadian Journal of Physiology and Pharmacology. 88: 986-95. PMID 20962898 DOI: 10.1139/y10-080 |
0.569 |
|
2010 |
Rafiqi FH, Zuber AM, Glover M, Richardson C, Fleming S, Jovanović S, Jovanović A, O'Shaughnessy KM, Alessi DR. Role of the WNK-activated SPAK kinase in regulating blood pressure. Embo Molecular Medicine. 2: 63-75. PMID 20091762 DOI: 10.1002/Emmm.200900058 |
0.68 |
|
2009 |
Glover M, Zuber AM, O'Shaughnessy KM. Renal and brain isoforms of WNK3 have opposite effects on NCCT expression. Journal of the American Society of Nephrology : Jasn. 20: 1314-22. PMID 19470686 DOI: 10.1681/Asn.2008050542 |
0.577 |
|
2008 |
Murthy M, Cope G, O'Shaughnessy KM. The acidic motif of WNK4 is crucial for its interaction with the K channel ROMK. Biochemical and Biophysical Research Communications. 375: 651-4. PMID 18755144 DOI: 10.1016/j.bbrc.2008.08.076 |
0.513 |
|
2007 |
Burton TJ, O'Shaughnessy KM, Brown MJ. The epithelial Na+ channel as a determinant of blood pressure Current Hypertension Reviews. 3: 45-49. DOI: 10.2174/157340207779815491 |
0.444 |
|
2006 |
Golbang AP, Cope G, Hamad A, Murthy M, Liu CH, Cuthbert AW, O'shaughnessy KM. Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved. American Journal of Physiology. Renal Physiology. 291: F1369-76. PMID 16788137 DOI: 10.1152/ajprenal.00468.2005 |
0.567 |
|
2006 |
Cope G, Murthy M, Golbang AP, Hamad A, Liu CH, Cuthbert AW, O'Shaughnessy KM. WNK1 affects surface expression of the ROMK potassium channel independent of WNK4. Journal of the American Society of Nephrology : Jasn. 17: 1867-74. PMID 16775035 DOI: 10.1681/ASN.2005111224 |
0.576 |
|
2006 |
Yasmin, O'Shaughnessy KM, McEniery CM, Cockcroft JR, Wilkinson IB. Genetic variation in fibrillin-1 gene is not associated with arterial stiffness in apparently healthy individuals. Journal of Hypertension. 24: 499-502. PMID 16467653 DOI: 10.1097/01.Hjh.0000209986.74477.18 |
0.402 |
|
2005 |
Golbang AP, Murthy M, Hamad A, Liu CH, Cope G, Van't Hoff W, Cuthbert A, O'Shaughnessy KM. A new kindred with pseudohypoaldosteronism type II and a novel mutation (564D>H) in the acidic motif of the WNK4 gene. Hypertension. 46: 295-300. PMID 15998707 DOI: 10.1161/01.HYP.0000174326.96918.d6 |
0.557 |
|
2005 |
Cope G, Golbang A, O'Shaughnessy KM. WNK kinases and the control of blood pressure. Pharmacology & Therapeutics. 106: 221-31. PMID 15866321 DOI: 10.1016/J.Pharmthera.2004.11.010 |
0.405 |
|
2003 |
Hong G, Lockhart A, Davis B, Rahmoune H, Baker S, Ye L, Thompson P, Shou Y, O'Shaughnessy K, Ronco P, Brown J. PPARgamma activation enhances cell surface ENaCalpha via up-regulation of SGK1 in human collecting duct cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1966-8. PMID 12923071 DOI: 10.1096/Fj.03-0181Fje |
0.354 |
|
2001 |
O'Shaughnessy KM, Fu B, Downing S, Morris NH. Thrombophilic polymorphisms in pre-eclampsia: altered frequency of the functional 98C>T polymorphism of glycoprotein IIIa. Journal of Medical Genetics. 38: 775-7. PMID 11732486 DOI: 10.1136/Jmg.38.11.775 |
0.36 |
|
2001 |
O'Shaughnessy KM. The genetics of essential hypertension. British Journal of Clinical Pharmacology. 51: 5-11. PMID 11167660 DOI: 10.1046/J.1365-2125.2001.01254.X |
0.364 |
|
1998 |
O'Shaughnessy KM, Fu B, Johnson A, Gordon RD. Linkage of Gordon's syndrome to the long arm of chromosome 17 in a region recently linked to familial essential hypertension. Journal of Human Hypertension. 12: 675-8. PMID 9819014 DOI: 10.1038/Sj.Jhh.1000705 |
0.312 |
|
Low-probability matches (unlikely to be authored by this person) |
2009 |
Burton TJ, Cope G, Wang J, Sim JC, Azizan EAB, O'Shaughnessy KM, Brown MJ. Corrigendum to: "Expression of the epithelial Na+ channel and other components of an aldosterone response pathway in human adrenocortical cells" [European Journal of Pharmacology 613 (2009) 176-181] (DOI:10.1016/j.ejphar.2009.04.005) European Journal of Pharmacology. 617: 131. DOI: 10.1016/J.Ejphar.2009.06.034 |
0.295 |
|
2003 |
Sandilands AJ, O'Shaughnessy KM, Brown MJ. Greater inotropic and cyclic AMP responses evoked by noradrenaline through Arg389 beta 1-adrenoceptors versus Gly389 beta 1-adrenoceptors in isolated human atrial myocardium. British Journal of Pharmacology. 138: 386-92. PMID 12540530 DOI: 10.1038/Sj.Bjp.0705030 |
0.291 |
|
2005 |
Sandilands AJ, O'Shaughnessy KM. The functional significance of genetic variation within the beta-adrenoceptor. British Journal of Clinical Pharmacology. 60: 235-43. PMID 16120061 DOI: 10.1111/J.1365-2125.2005.02438.X |
0.282 |
|
2004 |
Hiby SE, Walker JJ, O'shaughnessy KM, Redman CW, Carrington M, Trowsdale J, Moffett A. Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. The Journal of Experimental Medicine. 200: 957-65. PMID 15477349 DOI: 10.1084/Jem.20041214 |
0.28 |
|
2004 |
Sandilands A, Yeo G, Brown MJ, O'Shaughnessy KM. Functional responses of human beta1 adrenoceptors with defined haplotypes for the common 389R>G and 49S>G polymorphisms. Pharmacogenetics. 14: 343-9. PMID 15247626 DOI: 10.1097/00008571-200406000-00003 |
0.278 |
|
2011 |
Mercier-Zuber A, O'Shaughnessy KM. Role of SPAK and OSR1 signalling in the regulation of NaCl cotransporters. Current Opinion in Nephrology and Hypertension. 20: 534-40. PMID 21610494 DOI: 10.1097/MNH.0b013e3283484b06 |
0.276 |
|
2013 |
Chowdhury JA, Liu CH, Zuber AM, O'Shaughnessy KM. An inducible transgenic mouse model for familial hypertension with hyperkalaemia (Gordon's syndrome or pseudohypoaldosteronism type II). Clinical Science (London, England : 1979). 124: 701-8. PMID 23336180 DOI: 10.1042/CS20120430 |
0.273 |
|
2000 |
O'shaughnessy KM, Fu B, Dickerson C, Thurston D, Brown MJ. The gain-of-function G389R variant of the β1-adrenoceptor does not influence blood pressure or heart rate response to β-blockade in hypertensive subjects Clinical Science. 99: 233-238. DOI: 10.1042/Cs0990233 |
0.269 |
|
2009 |
O'Shaughnessy KM. Dissecting complex traits: recent advances in hypertension genomics. Genome Medicine. 1: 43. PMID 19439027 DOI: 10.1186/gm43 |
0.242 |
|
2008 |
Yasmin, O'Shaughnessy KM. Genetics of arterial structure and function: towards new biomarkers for aortic stiffness? Clinical Science (London, England : 1979). 114: 661-77. PMID 18442360 DOI: 10.1042/CS20070369 |
0.242 |
|
1997 |
Hingorani A, Liang C, Fatibene J, Parsons A, Hopper R, Trutwein D, Stephens N, O'Shaughnessy K, Brown M. A Variant of the Endothelial Nitric Oxide Synthase Gene is a Risk Factor for Coronary Atherosclerosis Clinical Science. 93: 18P-18P. DOI: 10.1042/Cs093018Pa |
0.24 |
|
2006 |
Yasmin, McEniery CM, O'Shaughnessy KM, Harnett P, Arshad A, Wallace S, Maki-Petaja K, McDonnell B, Ashby MJ, Brown J, Cockcroft JR, Wilkinson IB. Variation in the human matrix metalloproteinase-9 gene is associated with arterial stiffness in healthy individuals. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1799-805. PMID 16709939 DOI: 10.1161/01.ATV.0000227717.46157.32 |
0.238 |
|
2023 |
O'Shaughnessy KM. Genetic Markers Regulating Blood Pressure in Extreme Discordant Sib Pairs. Genes. 14. PMID 37895212 DOI: 10.3390/genes14101862 |
0.236 |
|
1983 |
Heal DJ, O'Shaughnessy KM, Smith SL, Nutt DJ. Hypophysectomy alters both 5-hydroxytryptamine- and alpha 2-adrenoceptor-mediated behavioural changes in the rat. European Journal of Pharmacology. 89: 167-71. PMID 6305683 DOI: 10.1016/0014-2999(83)90624-6 |
0.235 |
|
2000 |
Sharma P, Fatibene J, Ferraro F, Jia H, Monteith S, Brown C, Clayton D, O'Shaughnessy K, Brown MJ. Genome-wide search for susceptibility loci to human essential hypertension Hypertension. 35: 1291-1296. PMID 10856279 DOI: 10.1161/01.Hyp.35.6.1291 |
0.228 |
|
2001 |
Farzaneh-Far A, Davies JD, Braam LA, Spronk HM, Proudfoot D, Chan SW, O'Shaughnessy KM, Weissberg PL, Vermeer C, Shanahan CM. A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. The Journal of Biological Chemistry. 276: 32466-73. PMID 11425864 DOI: 10.1074/Jbc.M104909200 |
0.227 |
|
2001 |
Foo R, O'Shaughnessy KM, Brown MJ. Hyperaldosteronism: recent concepts, diagnosis, and management. Postgraduate Medical Journal. 77: 639-44. PMID 11571370 DOI: 10.1136/Pmj.77.912.639 |
0.224 |
|
1999 |
Lewis I, Lachmeijer G, Downing S, Dekker G, Glazebrook C, Clayton D, Morris NH, O'Shaughnessy KM. Failure to detect linkage of preeclampsia to the region of the NOS3 locus on chromosome 7q. American Journal of Human Genetics. 64: 310-3. PMID 9915975 DOI: 10.1086/302179 |
0.216 |
|
2011 |
Carss KJ, Stowasser M, Gordon RD, O'Shaughnessy KM. Further study of chromosome 7p22 to identify the molecular basis of familial hyperaldosteronism type II. Journal of Human Hypertension. 25: 560-4. PMID 20927129 DOI: 10.1038/jhh.2010.93 |
0.213 |
|
2001 |
Hu CT, O'Shaughnessy KM. Glycerol-enhanced mini-polyacrylamide gel electrophoresis for the separation of differentially expressed DNA fragments in cDNA representational difference analysis. Electrophoresis. 22: 1063-8. PMID 11358126 DOI: 10.1002/1522-2683()22:6<1063::Aid-Elps1063>3.0.Co;2-S |
0.205 |
|
2000 |
O'Shaughnessy KM, Fu B, Dickerson C, Thurston D, Brown MJ. The gain-of-function G389R variant of the beta1-adrenoceptor does not influence blood pressure or heart rate response to beta-blockade in hypertensive subjects. Clinical Science (London, England : 1979). 99: 233-8. PMID 11787477 |
0.202 |
|
2006 |
O'Shaughnessy KM, Karet FE. Salt handling and hypertension. Annual Review of Nutrition. 26: 343-65. PMID 16602929 DOI: 10.1146/annurev.nutr.26.061505.111316 |
0.198 |
|
2004 |
O'Shaughnessy KM, Karet FE. Salt handling and hypertension. The Journal of Clinical Investigation. 113: 1075-81. PMID 15085183 DOI: 10.1172/JCI21560 |
0.194 |
|
2009 |
Burton TJ, Cope G, Wang J, Sim JC, Azizan EA, O'Shaughnessy KM, Brown MJ. Expression of the epithelial Na(+) channel and other components of an aldosterone response pathway in human adrenocortical cells. European Journal of Pharmacology. 613: 176-81. PMID 19371736 DOI: 10.1016/J.Ejphar.2009.04.005 |
0.188 |
|
2006 |
Yasmin, Wilkinson IB, O'Shaughnessy KM. Influence of fibrillin-1 genotype on aortic stiffness in men: a note of caution. Journal of Applied Physiology (Bethesda, Md. : 1985). 100: 1431; author reply 1. PMID 16540720 DOI: 10.1152/japplphysiol.01408.2005 |
0.179 |
|
2006 |
O'Shaughnessy KM. Role of diet in hypertension management. Current Hypertension Reports. 8: 292-7. PMID 16884659 |
0.176 |
|
2010 |
Cheriyan J, O'Shaughnessy KM, Brown MJ. Primary prevention of CVD: treating hypertension. Bmj Clinical Evidence. 2010. PMID 21733198 |
0.172 |
|
1999 |
O'Shaughnessy KM, Fu B, Ferraro F, Lewis I, Downing S, Morris NH. Factor V Leiden and thermolabile methylenetetrahydrofolate reductase gene variants in an East Anglian preeclampsia cohort. Hypertension. 33: 1338-41. PMID 10373212 |
0.161 |
|
2006 |
O'Shaughnessy KM. HapMap, pharmacogenomics, and the goal of personalized prescribing. British Journal of Clinical Pharmacology. 61: 783-6. PMID 16722846 DOI: 10.1111/j.1365-2125.2006.02683.x |
0.15 |
|
1999 |
Hingorani AD, Liang CF, Fatibene J, Lyon A, Monteith S, Parsons A, Haydock S, Hopper RV, Stephens NG, O'Shaughnessy KM, Brown MJ. A common variant of the endothelial nitric oxide synthase (Glu298-->Asp) is a major risk factor for coronary artery disease in the UK. Circulation. 100: 1515-20. PMID 10510054 DOI: 10.1161/01.Cir.100.14.1515 |
0.147 |
|
2008 |
Brenner T, O'Shaughnessy KM. Both TASK-3 and TREK-1 two-pore loop K channels are expressed in H295R cells and modulate their membrane potential and aldosterone secretion. American Journal of Physiology. Endocrinology and Metabolism. 295: E1480-6. PMID 18854423 DOI: 10.1152/ajpendo.90652.2008 |
0.143 |
|
2005 |
Sandilands AJ, Parameshwar J, Large S, Brown MJ, O'Shaughnessy KM. Confirmation of a role for the 389R>G beta-1 adrenoceptor polymorphism on exercise capacity in heart failure. Heart (British Cardiac Society). 91: 1613-4. PMID 16287753 DOI: 10.1136/Hrt.2004.047282 |
0.143 |
|
1997 |
Sharma P, Pathan S, Fatibene J, Jia H, Thompson D, Monteith S, Clayton D, O'Shaughnessy K, Brown MJ. Annual Scientific Meeting of the British Hypertension Society. Wills Hall, University of Bristol, 15-17 September 1997. Genome wide search for susceptibility loci in essential hypertension: Early results Journal of Hypertension. 15: 1529. |
0.142 |
|
1998 |
Liyou N, Simons L, Friedlander Y, Simons J, McCallum J, O'Shaughnessy K, Davis D, Johnson A. Coronary artery disease is not associated with the E298→D variant of the constitutive, endothelial nitric oxide synthase gene [2] Clinical Genetics. 54: 528-529. PMID 9894802 |
0.112 |
|
2021 |
Kulkarni S, Rao R, Goodman JDH, Connolly K, O'Shaughnessy KM. Nonadherence to antihypertensive medications amongst patients with uncontrolled hypertension: A retrospective study. Medicine. 100: e24654. PMID 33832064 DOI: 10.1097/MD.0000000000024654 |
0.103 |
|
2000 |
O'shaughnessy KM, Ferraro F, Fu B, Downing S, Morris NH. Identification of monozygotic twins that are concordant for preeclampsia. American Journal of Obstetrics and Gynecology. 182: 1156-7. PMID 10819852 DOI: 10.1067/mob.2000.105429 |
0.098 |
|
1992 |
O'Shaughnessy KM, Newman CM, Warren JB. Inhibition in the rat of nitric oxide synthesis in vivo does not attenuate the hypotensive action of acetylcholine, ATP or bradykinin. Experimental Physiology. 77: 285-92. PMID 1581056 |
0.094 |
|
2007 |
Broughton Pipkin F, Kalsheker N, Morgan L, O'Malley S, Henfrey M, Arulkumaran S, Symonds I, Cameron A, Dominiczak A, McDade M, Kwong Lee W, McCulloch J, Caulfield M, Farrall M, Kilby M, et al. Babies, pre-eclamptic mothers and grandparents: A three-generation phenotyping study Journal of Hypertension. 25: 849-854. PMID 17351378 DOI: 10.1097/Hjh.0B013E32803Fb634 |
0.092 |
|
1994 |
Hirokawa K, O'Shaughnessy KM, Ramrakha P, Wilkins MR. Inhibition of nitric oxide synthesis in vascular smooth muscle by retinoids. British Journal of Pharmacology. 113: 1448-54. PMID 7534188 |
0.088 |
|
1992 |
Kobayashi H, Adachi M, Satoh H, Nishikata H, Imai T, O'Shaughnessy KM, Fuller RW, Takahashi T. Mechanisms of PAF-induced airway hyperresponsiveness in the dog: The effect of ketotifen and the role of thromboxane A2 Immunology and Allergy Practice. 14: 433-443. |
0.084 |
|
1991 |
Taylor IK, Ward PS, O'Shaughnessy KM, Dollery CT, Black P, Barrow SE, Taylor GW, Fuller RW. Thromboxane A2 biosynthesis in acute asthma and after antigen challenge. The American Review of Respiratory Disease. 143: 119-25. PMID 1986668 DOI: 10.1164/ajrccm/143.1.119 |
0.077 |
|
2016 |
Kennard L, O'Shaughnessy KM. Treating hypertension in patients with medical comorbidities. Bmj (Clinical Research Ed.). 352: i101. PMID 26884124 DOI: 10.1136/bmj.i101 |
0.075 |
|
1986 |
Heal DJ, Philpot J, O'Shaughnessy KM, Davies CL. The influence of central noradrenergic function on 5-HT2-mediated head-twitch responses in mice: possible implications for the actions of antidepressant drugs. Psychopharmacology. 89: 414-20. PMID 3018823 DOI: 10.1007/BF02412113 |
0.074 |
|
1983 |
O'Shaughnessy K, Hladky SB. Transient currents carried by the uncoupler, carbonyl cyanide m-chlorophenylhydrazone Bba - Bioenergetics. 724: 381-387. PMID 6615824 DOI: 10.1016/0005-2728(83)90097-X |
0.067 |
|
1994 |
Sala A, Folco G, O'Shaughnessy KM. Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion [1] American Journal of Respiratory and Critical Care Medicine. 150: 287. PMID 8025766 |
0.051 |
|
1993 |
O'Shaughnessy KM, Wellings R, Gillies B, Fuller RW. Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion. The American Review of Respiratory Disease. 147: 1472-6. PMID 8389108 DOI: 10.1164/ajrccm/147.6_Pt_1.1472 |
0.051 |
|
1992 |
Taylor IK, O'Shaughnessy KM, Choudry NB, Adachi M, Palmer JB, Fuller RW. A comparative study in atopic subjects with asthma of the effects of salmeterol and salbutamol on allergen-induced bronchoconstriction, increase in airway reactivity, and increase in urinary leukotriene E4 excretion. The Journal of Allergy and Clinical Immunology. 89: 575-83. PMID 1346794 DOI: 10.1016/0091-6749(92)90325-V |
0.049 |
|
1991 |
O'Shaughnessy KM, Taylor IK, Fuller RW. β2-agonists in asthma (VII) Lancet. 337: 45-46. |
0.034 |
|
1993 |
O'Shaughnessy KM, Taylor IK, O'Connor B, O'Connell F, Thomson H, Dollery CT. Potent leukotriene D4 receptor antagonist ICI 204,219 given by the inhaled route inhibits the early but not the late phase of allergen-induced bronchoconstriction. The American Review of Respiratory Disease. 147: 1431-5. PMID 8389105 DOI: 10.1164/ajrccm/147.6_Pt_1.1431 |
0.031 |
|
1991 |
Taylor IK, O'Shaughnessy KM, Fuller RW, Dollery CT. Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects. Lancet (London, England). 337: 690-4. PMID 1672176 DOI: 10.1016/0140-6736(91)90277-V |
0.028 |
|
1996 |
Taylor IK, Hill AA, Hayes M, Rhodes CG, O'Shaughnessy KM, O'Connor BJ, Jones HA, Hughes JM, Jones T, Pride NB, Fuller RW. Imaging allergen-invoked airway inflammation in atopic asthma with [18F]-fluorodeoxyglucose and positron emission tomography. Lancet (London, England). 347: 937-40. PMID 8598758 DOI: 10.1016/S0140-6736(96)91416-6 |
0.024 |
|
2016 |
O'Shaughnessy KM, Kennard L. Authors' reply to Ninan and Millar and Abou-saleh. Bmj (Clinical Research Ed.). 353: i2253. PMID 27118732 |
0.023 |
|
2016 |
O'Shaughnessy KM, Kennard L. Authors' reply to Ninan and Millar and Abou-saleh Bmj (Online). 353. DOI: 10.1136/bmj.i2253 |
0.023 |
|
1997 |
Taylor IK, Rhodes CG, O'Shaughnessy KM, Liistro G. Noninvasive imaging of airway inflammation in asthma Monaldi Archives For Chest Disease. 52: 197. |
0.017 |
|
2018 |
O'Shaughnessy K. SUPPORTIVE CARE NEEDS OF PROSTATE CANCER SURVIVORS. Australian Nursing & Midwifery Journal. 24: 34. PMID 29251471 |
0.017 |
|
2000 |
Ramkissoon Y, Ghoorahoo H, Haydock SF, O'Shaughnessy KM. An unusual complication of carcinoma of the caecum. Postgraduate Medical Journal. 76: 438, 451-2. PMID 10878219 |
0.013 |
|
2011 |
Baulis H, Montagu A, Davies E, Wake M, O'Shaughnessy K, Deuter K, Gillham D, McCutcheon H. The use of audio-visual communication strategies in the emergency waiting room to improve patient and staff satisfaction Australasian Emergency Nursing Journal. 14: S28-S29. DOI: 10.1016/j.aenj.2011.09.072 |
0.01 |
|
2006 |
O'Shaughnessy K. Pharmacogenomics, Methods and Protocols British Journal of Clinical Pharmacology. 62: 253-253. DOI: 10.1111/j.1365-2125.2006.02624.x |
0.01 |
|
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