Thomas Scammell - Publications

Harvard Medical School, Boston, MA, United States 
sleep anatomy and physiology, narcolepsy

115 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Balmuth EA, Scammell TE. Harriet Tubman's Hypersomnia: Insights from Historical and Medical Perspectives. Journal of General Internal Medicine. PMID 37740167 DOI: 10.1007/s11606-023-08414-x  0.317
2022 Dauvilliers Y, Bogan RK, Arnulf I, Scammell TE, St Louis EK, Thorpy MJ. Clinical considerations for the diagnosis of idiopathic hypersomnia. Sleep Medicine Reviews. 66: 101709. PMID 36401976 DOI: 10.1016/j.smrv.2022.101709  0.301
2022 Kroeger D, Thundercliffe J, Phung A, De Luca R, Geraci C, Bragg S, McCafferty KJ, Bandaru SS, Arrigoni E, Scammell TE. Glutamatergic PPT neurons control wakefulness and locomotion via distinct axonal projections. Sleep. PMID 36170177 DOI: 10.1093/sleep/zsac242  0.383
2022 De Luca R, Nardone S, Grace KP, Venner A, Cristofolini M, Bandaru SS, Sohn LT, Kong D, Mochizuki T, Viberti B, Zhu L, Zito A, Scammell TE, Saper CB, Lowell BB, et al. Orexin neurons inhibit sleep to promote arousal. Nature Communications. 13: 4163. PMID 35851580 DOI: 10.1038/s41467-022-31591-y  0.616
2022 Scammell TE, Saper CB. Major advances in sleep neurology: 2002-22. The Lancet. Neurology. 21: 678-680. PMID 35841898 DOI: 10.1016/S1474-4422(22)00263-0  0.541
2022 Burgess CR, Scammell TE. Catching Up on REMs. The New England Journal of Medicine. 386: 1950-1952. PMID 35584160 DOI: 10.1056/NEJMcibr2203101  0.708
2022 Shi SQ, Mahoney CE, Houdek P, Zhao W, Anderson MP, Zhuo X, Beaudet A, Sumova A, Scammell TE, Johnson CH. Circadian Rhythms and Sleep Are Dependent Upon Expression Levels of Key Ubiquitin Ligase . Frontiers in Behavioral Neuroscience. 16: 837523. PMID 35401134 DOI: 10.3389/fnbeh.2022.837523  0.403
2021 Coffey AA, Joyal AA, Yamanaka A, Scammell TE. The Impacts of Age and Sex in a Mouse Model of Childhood Narcolepsy. Frontiers in Neuroscience. 15: 644757. PMID 33746708 DOI: 10.3389/fnins.2021.644757  0.345
2021 Maski KP, Colclasure A, Little E, Steinhart E, Scammell TE, Navidi W, Diniz Behn C. Stability of Nocturnal Wake and Sleep Stages Defines CNS Disorders of Hypersomnolence. Sleep. PMID 33512510 DOI: 10.1093/sleep/zsab021  0.31
2020 Maski K, Pizza F, Liu S, Steinhart E, Little E, Colclasure A, Diniz Behn C, Vandi S, Antelmi E, Weller E, Scammell TE, Plazzi G. Defining Disrupted Nighttime Sleep and Assessing its Diagnostic Utility for Pediatric Narcolepsy Type 1. Sleep. PMID 32253429 DOI: 10.1093/Sleep/Zsaa066  0.373
2020 Adamantidis AR, Schmidt MH, Carter ME, Burdakov D, Peyron C, Scammell TE. A circuit perspective on narcolepsy. Sleep. PMID 31919524 DOI: 10.1093/Sleep/Zsz296  0.376
2020 Maski KP, Colclasure A, Little E, Steinhart E, Scammell T, Navidi W, Behn CD. 0951 Sleep Stabilization Patterns Define Pediatric CNS Hypersomnia Conditions Sleep. 43. DOI: 10.1093/Sleep/Zsaa056.947  0.417
2020 Maski KP, Pizza F, Colclasure A, Steinhart E, Little E, Behn CD, Vandi S, Antelmi E, Plazzi G, Scammell T. 0941 Defining Disrupted Nighttime Sleep in Pediatric Narcolepsy Sleep. 43. DOI: 10.1093/Sleep/Zsaa056.937  0.449
2020 Kroeger D, Thundercliffe JA, Phung A, Geraci C, DeLuca R, Bragg S, Arrigoni E, Scammell TE. 0156 Activation of Glutamatergic PPT Neurons and Their Projections Promotes Arousal, and Distinct Wake Behaviors Sleep. 43: A61-A62. DOI: 10.1093/Sleep/Zsaa056.154  0.476
2020 Mahoney CE, Zhao W, Coffey A, Woods C, Kroeger D, Scammell T. 0005 Cataplexy Triggered by Social Cues: A Role for Oxytocin in the Amygdala Sleep. 43: A2-A2. DOI: 10.1093/Sleep/Zsaa056.004  0.46
2019 Mahoney CE, Mochizuki T, Scammell TE. Dual orexin receptor antagonists increase sleep and cataplexy in wild type mice. Sleep. PMID 31830270 DOI: 10.1093/Sleep/Zsz302  0.337
2019 Lombardi F, Gómez-Extremera M, Bernaola-Galván P, Vetrivelan R, Saper CB, Scammell TE, Ivanov PC. Critical dynamics and coupling in bursts of cortical rhythms indicate non-homeostatic mechanism for sleep-stage transitions and dual role of VLPO neurons in both sleep and wake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31694962 DOI: 10.1523/JNEUROSCI.1278-19.2019  0.571
2019 Venner A, Mochizuki T, De Luca R, Anaclet C, Scammell TE, Saper CB, Arrigoni E, Fuller PM. Reassessing the role of histaminergic tuberomammillary neurons in arousal control. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31548232 DOI: 10.1523/Jneurosci.1032-19.2019  0.553
2019 Gisabella B, Scammell T, Bandaru SS, Saper CB. Regulation of hippocampal dendritic spines following sleep deprivation. The Journal of Comparative Neurology. PMID 31454077 DOI: 10.1002/cne.24764  0.593
2019 Bassetti CLA, Adamantidis A, Burdakov D, Han F, Gay S, Kallweit U, Khatami R, Koning F, Kornum BR, Lammers GJ, Liblau RS, Luppi PH, Mayer G, Pollmächer T, Sakurai T, ... ... Scammell TE, et al. Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment. Nature Reviews. Neurology. PMID 31324898 DOI: 10.1038/S41582-019-0226-9  0.373
2019 McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, ... ... Scammell TE, et al. Sleep modulates haematopoiesis and protects against atherosclerosis. Nature. PMID 30760925 DOI: 10.1038/S41586-019-0948-2  0.37
2019 Agostinelli LJ, Geerling JC, Scammell TE. Basal forebrain subcortical projections. Brain Structure & Function. PMID 30612231 DOI: 10.1007/S00429-018-01820-6  0.668
2019 Sullivan L, Scammell T, Pavlova M, Wang W, Pham J, Videnovic A. 0620 Effect Of Antidepressants On Sleep Architecture Sleep. 42. DOI: 10.1093/Sleep/Zsz067.618  0.444
2019 Maski K, Colclasure A, Little E, Steinhart E, Scammell T, Navidi W, Behn CD. Sleep stabilization patterns define pediatric CNS hypersomnia conditions Sleep Medicine. 64. DOI: 10.1016/J.Sleep.2019.11.689  0.417
2019 Maski K, Colclasure A, Behn CD, Scammell T, Plazzi G, Vandi S, Antelmi E, Pizza F. Defining disrupted nighttime sleep (DNS) in pediatric narcolepsy Sleep Medicine. 64. DOI: 10.1016/J.Sleep.2019.11.688  0.449
2018 Mahoney CE, Cogswell A, Koralnik IJ, Scammell TE. The neurobiological basis of narcolepsy. Nature Reviews. Neuroscience. PMID 30546103 DOI: 10.1038/S41583-018-0097-X  0.364
2018 Kroeger D, Absi G, Gagliardi C, Bandaru SS, Madara JC, Ferrari LL, Arrigoni E, Münzberg H, Scammell TE, Saper CB, Vetrivelan R. Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice. Nature Communications. 9: 4129. PMID 30297727 DOI: 10.1038/S41467-018-06590-7  0.621
2018 Scammell TE, Jackson AC, Franks NP, Wisden W, Dauvilliers Y. Histamine: Neural circuits and new medications. Sleep. PMID 30239935 DOI: 10.1093/Sleep/Zsy183  0.348
2018 Naganuma F, Bandaru S, Absi G, Mahoney CE, Scammell TE, Vetrivelan R. Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy. Neurobiology of Disease. PMID 30149182 DOI: 10.1016/J.Nbd.2018.08.012  0.468
2017 Svetnik V, Snyder ES, Tao P, Scammell TE, Roth T, Lines C, Herring WJ. Insight into Reduction of Wakefulness by Suvorexant in Patients with Insomnia: Analysis of Wake Bouts. Sleep. PMID 29112763 DOI: 10.1093/sleep/zsx178  0.323
2017 Schoch SF, Werth E, Poryazova R, Scammell TE, Baumann CR, Imbach LL. Dysregulation of Sleep Behavioral States in Narcolepsy. Sleep. PMID 29029348 DOI: 10.1093/sleep/zsx170  0.355
2017 Alexandre C, Latremoliere A, Ferreira A, Miracca G, Yamamoto M, Scammell TE, Woolf CJ. Decreased alertness due to sleep loss increases pain sensitivity in mice. Nature Medicine. PMID 28481358 DOI: 10.1038/nm.4329  0.334
2017 Mahoney CE, Agostinelli LJ, Brooks JN, Lowell BB, Scammell TE. GABAergic neurons of the central amygdala promote cataplexy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28235898 DOI: 10.1523/Jneurosci.4065-15.2017  0.37
2017 Scammell TE, Arrigoni E, Lipton JO. Neural Circuitry of Wakefulness and Sleep. Neuron. 93: 747-765. PMID 28231463 DOI: 10.1016/J.Neuron.2017.01.014  0.366
2017 Peng YJ, Zhang X, Gridina A, Chupikova I, McCormick DL, Thomas RJ, Scammell TE, Kim G, Vasavda C, Nanduri J, Kumar GK, Semenza GL, Snyder SH, Prabhakar NR. Complementary roles of gasotransmitters CO and H2S in sleep apnea. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115703 DOI: 10.1073/Pnas.1620717114  0.353
2016 Kroeger D, Ferrari LL, Petit G, Mahoney CE, Fuller PM, Arrigoni E, Scammell TE. Cholinergic, glutamatergic, and GABAergic neurons of the PPT have distinct effects on sleep/wake behavior in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28039375 DOI: 10.1523/Jneurosci.1405-16.2016  0.453
2016 Agostinelli LJ, Ferrari LL, Mahoney CE, Mochizuki T, Lowell BB, Arrigoni E, Scammell TE. Descending Projections from the Basal Forebrain to the Orexin Neurons in Mice. The Journal of Comparative Neurology. PMID 27997037 DOI: 10.1002/Cne.24158  0.327
2016 Garfield AS, Shah BP, Burgess CR, Li MM, Li C, Steger JS, Madara JC, Campbell JN, Kroeger D, Scammell TE, Tannous BA, Myers MG, Andermann ML, Krashes MJ, Lowell BB. Dynamic GABAergic afferent modulation of AgRP neurons. Nature Neuroscience. PMID 27643429 DOI: 10.1038/Nn.4392  0.754
2016 Gavrilov YV, Ellison BA, Yamamoto M, Reddy H, Haybaeck J, Mignot E, Baumann CR, Scammell TE, Valko PO. Disrupted Sleep in Narcolepsy: Exploring the Integrity of Galanin Neurons in the Ventrolateral Preoptic Area. Sleep. PMID 26951397 DOI: 10.5665/Sleep.5754  0.444
2015 Geerling JC, Kim MY, Mahoney CE, Abbott SB, Agostinelli LJ, Garfield AS, Krashes MJ, Lowell BB, Scammell TE. Genetic identity of thermosensory relay neurons in the lateral parabrachial nucleus. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00094.2015. PMID 26491097 DOI: 10.1152/Ajpregu.00094.2015  0.685
2015 Branch AF, Navidi W, Tabuchi S, Terao A, Yamanaka A, Scammell TE, Behn CD. Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness. Sleep. PMID 26446125 DOI: 10.5665/sleep.5446  0.444
2015 Scammell TE. Overview of sleep: the neurologic processes of the sleep-wake cycle. The Journal of Clinical Psychiatry. 76: e13. PMID 26035194 DOI: 10.4088/JCP.14046tx1c  0.351
2015 Oishi Y, Yoshida K, Scammell TE, Urade Y, Lazarus M, Saper CB. The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep. Brain, Behavior, and Immunity. 47: 172-7. PMID 25532785 DOI: 10.1016/j.bbi.2014.11.019  0.538
2015 Valko PO, Gavrilov YV, Yamamoto M, Finn K, Reddy H, Haybaeck J, Weis S, Scammell TE, Baumann CR. Damage to histaminergic tuberomammillary neurons and other hypothalamic neurons with traumatic brain injury. Annals of Neurology. 77: 177-82. PMID 25363332 DOI: 10.1002/ana.24298  0.342
2015 Reiter J, Katz E, Scammell TE, Maski K. Usefulness of a Nocturnal SOREMP for Diagnosing Narcolepsy with Cataplexy in a Pediatric Population. Sleep. 38: 859-65. PMID 25325489 DOI: 10.5665/sleep.4728  0.333
2014 Bastianini S, Berteotti C, Gabrielli A, Del Vecchio F, Amici R, Alexandre C, Scammell TE, Gazea M, Kimura M, Lo Martire V, Silvani A, Zoccoli G. SCOPRISM: a new algorithm for automatic sleep scoring in mice. Journal of Neuroscience Methods. 235: 277-84. PMID 25092499 DOI: 10.1016/j.jneumeth.2014.07.018  0.316
2014 Williams RH, Chee MJ, Kroeger D, Ferrari LL, Maratos-Flier E, Scammell TE, Arrigoni E. Optogenetic-mediated release of histamine reveals distal and autoregulatory mechanisms for controlling arousal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6023-9. PMID 24760861 DOI: 10.1523/Jneurosci.4838-13.2014  0.449
2014 Weng FJ, Williams RH, Hawryluk JM, Lu J, Scammell TE, Saper CB, Arrigoni E. Carbachol excites sublaterodorsal nucleus neurons projecting to the spinal cord. The Journal of Physiology. 592: 1601-17. PMID 24344163 DOI: 10.1113/Jphysiol.2013.261800  0.615
2013 Saper CB, Scammell TE. Emerging therapeutics in sleep. Annals of Neurology. 74: 435-40. PMID 24038193 DOI: 10.1002/ana.24000  0.534
2013 Valko PO, Gavrilov YV, Yamamoto M, Reddy H, Haybaeck J, Mignot E, Baumann CR, Scammell TE. Increase of histaminergic tuberomammillary neurons in narcolepsy. Annals of Neurology. 74: 794-804. PMID 24006291 DOI: 10.1002/Ana.24019  0.347
2013 Kantor S, Mochizuki T, Lops SN, Ko B, Clain E, Clark E, Yamamoto M, Scammell TE. Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice. Sleep. 36: 1129-38. PMID 23904672 DOI: 10.5665/sleep.2870  0.342
2013 Oishi Y, Williams RH, Agostinelli L, Arrigoni E, Fuller PM, Mochizuki T, Saper CB, Scammell TE. Role of the medial prefrontal cortex in cataplexy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9743-51. PMID 23739971 DOI: 10.1523/JNEUROSCI.0499-13.2013  0.504
2013 Burgess CR, Oishi Y, Mochizuki T, Peever JH, Scammell TE. Amygdala lesions reduce cataplexy in orexin knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9734-42. PMID 23739970 DOI: 10.1523/Jneurosci.5632-12.2013  0.759
2013 Alexandre C, Andermann ML, Scammell TE. Control of arousal by the orexin neurons. Current Opinion in Neurobiology. 23: 752-9. PMID 23683477 DOI: 10.1016/J.Conb.2013.04.008  0.684
2012 Imbach LL, Werth E, Kallweit U, Sarnthein J, Scammell TE, Baumann CR. Inter-hemispheric oscillations in human sleep. Plos One. 7: e48660. PMID 23144920 DOI: 10.1371/journal.pone.0048660  0.347
2012 Burgess CR, Scammell TE. Narcolepsy: neural mechanisms of sleepiness and cataplexy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 12305-11. PMID 22956821 DOI: 10.1523/Jneurosci.2630-12.2012  0.697
2012 Saper CB, Romanovsky AA, Scammell TE. Neural circuitry engaged by prostaglandins during the sickness syndrome. Nature Neuroscience. 15: 1088-95. PMID 22837039 DOI: 10.1038/nn.3159  0.385
2011 España RA, Scammell TE. Sleep neurobiology from a clinical perspective. Sleep. 34: 845-58. PMID 21731134 DOI: 10.5665/SLEEP.1112  0.422
2011 Mochizuki T, Arrigoni E, Marcus JN, Clark EL, Yamamoto M, Honer M, Borroni E, Lowell BB, Elmquist JK, Scammell TE. Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 4471-6. PMID 21368172 DOI: 10.1073/pnas.1012456108  0.442
2011 Burgess C, Peever J, Scammell T. M-N-128 THE AMYGDALA IS NECESSARY FOR TRIGGERING CATAPLEXY IN OREXIN KO MICE Sleep Medicine. 12: S57. DOI: 10.1016/S1389-9457(11)70208-8  0.709
2010 Saper CB, Fuller PM, Pedersen NP, Lu J, Scammell TE. Sleep state switching. Neuron. 68: 1023-42. PMID 21172606 DOI: 10.1016/J.Neuron.2010.11.032  0.546
2010 Diniz Behn CG, Klerman EB, Mochizuki T, Lin SC, Scammell TE. Abnormal sleep/wake dynamics in orexin knockout mice. Sleep. 33: 297-306. PMID 20337187 DOI: 10.1093/Sleep/33.3.297  0.321
2010 Arrigoni E, Mochizuki T, Scammell TE. Activation of the basal forebrain by the orexin/hypocretin neurones. Acta Physiologica (Oxford, England). 198: 223-35. PMID 19723027 DOI: 10.1111/j.1748-1716.2009.02036.x  0.391
2009 Kantor S, Mochizuki T, Janisiewicz AM, Clark E, Nishino S, Scammell TE. Orexin neurons are necessary for the circadian control of REM sleep. Sleep. 32: 1127-34. PMID 19750917  0.42
2008 Diniz Behn CG, Kopell N, Brown EN, Mochizuki T, Scammell TE. Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling. Journal of Neurophysiology. 99: 3090-103. PMID 18417630 DOI: 10.1152/jn.01243.2007  0.424
2007 España RA, McCormack SL, Mochizuki T, Scammell TE. Running promotes wakefulness and increases cataplexy in orexin knockout mice. Sleep. 30: 1417-25. PMID 18041476  0.301
2007 Behn CG, Brown EN, Scammell TE, Kopell NJ. Mathematical model of network dynamics governing mouse sleep-wake behavior. Journal of Neurophysiology. 97: 3828-40. PMID 17409167 DOI: 10.1152/jn.01184.2006  0.367
2007 Scammell TE, Saper CB. Orexins: looking forward to sleep, back at addiction. Nature Medicine. 13: 126-8. PMID 17290266 DOI: 10.1038/nm0207-126  0.526
2006 Mochizuki T, Klerman EB, Sakurai T, Scammell TE. Elevated body temperature during sleep in orexin knockout mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 291: R533-40. PMID 16556901 DOI: 10.1152/Ajpregu.00887.2005  0.311
2006 Yoshida K, McCormack S, España RA, Crocker A, Scammell TE. Afferents to the orexin neurons of the rat brain. The Journal of Comparative Neurology. 494: 845-61. PMID 16374809 DOI: 10.1002/Cne.20859  0.35
2006 Scammell TE. Narcolepsy and other neurological sleep disorders Principles of Molecular Medicine. 1153-1159. DOI: 10.1007/978-1-59259-963-9_120  0.302
2005 Saper CB, Cano G, Scammell TE. Homeostatic, circadian, and emotional regulation of sleep. The Journal of Comparative Neurology. 493: 92-8. PMID 16254994 DOI: 10.1002/cne.20770  0.58
2005 Saper CB, Scammell TE, Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature. 437: 1257-63. PMID 16251950 DOI: 10.1038/Nature04284  0.577
2005 Crocker A, España RA, Papadopoulou M, Saper CB, Faraco J, Sakurai T, Honda M, Mignot E, Scammell TE. Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology. 65: 1184-8. PMID 16247044 DOI: 10.1212/01.Wnl.0000168173.71940.Ab  0.513
2005 Scammell TE, Saper CB. Orexin, drugs and motivated behaviors. Nature Neuroscience. 8: 1286-8. PMID 16189534 DOI: 10.1038/nn1005-1286  0.51
2005 Arrigoni E, Crocker AJ, Saper CB, Greene RW, Scammell TE. Deletion of presynaptic adenosine A1 receptors impairs the recovery of synaptic transmission after hypoxia. Neuroscience. 132: 575-80. PMID 15837119 DOI: 10.1016/j.neuroscience.2004.12.009  0.425
2005 Anderson MP, Mochizuki T, Xie J, Fischler W, Manger JP, Talley EM, Scammell TE, Tonegawa S. Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep. Proceedings of the National Academy of Sciences of the United States of America. 102: 1743-8. PMID 15677322 DOI: 10.1073/Pnas.0409644102  0.343
2005 Willie JT, Renthal W, Chemelli RM, Miller MS, Scammell TE, Yanagisawa M, Sinton CM. Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates. Neuroscience. 130: 983-95. PMID 15652995 DOI: 10.1016/J.Neuroscience.2004.10.005  0.343
2005 Scammell TE, Saper CB. Erratum: Corrigendum: Orexin, drugs and motivated behaviors Nature Neuroscience. 8: 1791-1791. DOI: 10.1038/NN1205-1791D  0.354
2004 Lo CC, Chou T, Penzel T, Scammell TE, Strecker RE, Stanley HE, Ivanov PCh. Common scale-invariant patterns of sleep-wake transitions across mammalian species. Proceedings of the National Academy of Sciences of the United States of America. 101: 17545-8. PMID 15583127 DOI: 10.1073/Pnas.0408242101  0.339
2004 España RA, Scammell TE. Sleep neurobiology for the clinician. Sleep. 27: 811-20. PMID 15283019  0.412
2004 Mochizuki T, Crocker A, McCormack S, Yanagisawa M, Sakurai T, Scammell TE. Behavioral state instability in orexin knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6291-300. PMID 15254084 DOI: 10.1523/Jneurosci.0586-04.2004  0.359
2004 Gledhill RF, Bartel PR, Yoshida Y, Nishino S, Scammell TE. Narcolepsy caused by acute disseminated encephalomyelitis. Archives of Neurology. 61: 758-60. PMID 15148155 DOI: 10.1001/archneur.61.5.758  0.382
2004 Saper CB, Scammell TE. Modafinil: a drug in search of a mechanism. Sleep. 27: 11-2. PMID 14998230  0.335
2003 Kramer A, Yang FC, Snodgrass P, Li X, Scammell TE, Davis FC, Weitz CJ. Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling. Novartis Foundation Symposium. 253: 250-62; discussion 1. PMID 14712926  0.306
2003 Chou TC, Scammell TE, Gooley JJ, Gaus SE, Saper CB, Lu J. Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10691-702. PMID 14627654 DOI: 10.1523/Jneurosci.23-33-10691.2003  0.575
2003 Ko EM, Estabrooke IV, McCarthy M, Scammell TE. Wake-related activity of tuberomammillary neurons in rats. Brain Research. 992: 220-6. PMID 14625060 DOI: 10.1016/j.brainres.2003.08.044  0.407
2003 Mochizuki T, Scammell TE. Orexin/Hypocretin: wired for wakefulness. Current Biology : Cb. 13: R563-4. PMID 12867050 DOI: 10.1016/S0960-9822(03)00474-3  0.303
2003 Scammell TE, Arrigoni E, Thompson MA, Ronan PJ, Saper CB, Greene RW. Focal deletion of the adenosine A1 receptor in adult mice using an adeno-associated viral vector. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5762-70. PMID 12843280 DOI: 10.1523/Jneurosci.23-13-05762.2003  0.449
2003 Chamberlin NL, Arrigoni E, Chou TC, Scammell TE, Greene RW, Saper CB. Effects of adenosine on gabaergic synaptic inputs to identified ventrolateral preoptic neurons. Neuroscience. 119: 913-8. PMID 12831851 DOI: 10.1016/S0306-4522(03)00246-X  0.544
2003 Scammell TE. The neurobiology, diagnosis, and treatment of narcolepsy. Annals of Neurology. 53: 154-66. PMID 12557281 DOI: 10.1002/ana.10444  0.373
2003 Scammell T. Hypocretin Deficiency and HLA in Narcolepsy Nejm Journal Watch. 2003. DOI: 10.1056/Jn200302070000004  0.309
2002 Overeem S, Scammell TE, Lammers GJ. Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy. Current Opinion in Neurology. 15: 739-45. PMID 12447114 DOI: 10.1097/01.wco.0000044800.53746.5a  0.317
2002 Chou TC, Bjorkum AA, Gaus SE, Lu J, Scammell TE, Saper CB. Afferents to the ventrolateral preoptic nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 977-90. PMID 11826126 DOI: 10.1523/Jneurosci.22-03-00977.2002  0.596
2001 Scammell TE, Gerashchenko DY, Mochizuki T, McCarthy MT, Estabrooke IV, Sears CA, Saper CB, Urade Y, Hayaishi O. An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons. Neuroscience. 107: 653-63. PMID 11720788 DOI: 10.1016/S0306-4522(01)00383-9  0.602
2001 Saper CB, Chou TC, Scammell TE. The sleep switch: hypothalamic control of sleep and wakefulness. Trends in Neurosciences. 24: 726-31. PMID 11718878 DOI: 10.1016/S0166-2236(00)02002-6  0.597
2001 Gooley JJ, Lu J, Chou TC, Scammell TE, Saper CB. Melanopsin in cells of origin of the retinohypothalamic tract. Nature Neuroscience. 4: 1165. PMID 11713469 DOI: 10.1038/Nn768  0.394
2001 Scammell TE. Wakefulness: an eye-opening perspective on orexin neurons. Current Biology : Cb. 11: R769-71. PMID 11591333 DOI: 10.1016/S0960-9822(01)00466-3  0.323
2001 Chou TC, Lee CE, Lu J, Elmquist JK, Hara J, Willie JT, Beuckmann CT, Chemelli RM, Sakurai T, Yanagisawa M, Saper CB, Scammell TE. Orexin (hypocretin) neurons contain dynorphin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: RC168. PMID 11567079 DOI: 10.1523/Jneurosci.21-19-J0003.2001  0.514
2001 Scammell TE, Nishino S, Mignot E, Saper CB. Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke. Neurology. 56: 1751-3. PMID 11425947 DOI: 10.1212/Wnl.56.12.1751  0.425
2001 Estabrooke IV, McCarthy MT, Ko E, Chou TC, Chemelli RM, Yanagisawa M, Saper CB, Scammell TE. Fos expression in orexin neurons varies with behavioral state. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1656-62. PMID 11222656 DOI: 10.1523/Jneurosci.21-05-01656.2001  0.627
2000 Scammell TE, Estabrooke IV, McCarthy MT, Chemelli RM, Yanagisawa M, Miller MS, Saper CB. Hypothalamic arousal regions are activated during modafinil-induced wakefulness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8620-8. PMID 11069971 DOI: 10.1523/Jneurosci.20-22-08620.2000  0.58
2000 Oka T, Oka K, Scammell TE, Lee C, Kelly JF, Nantel F, Elmquist JK, Saper CB. Relationship of EP(1-4) prostaglandin receptors with rat hypothalamic cell groups involved in lipopolysaccharide fever responses. The Journal of Comparative Neurology. 428: 20-32. PMID 11058222 DOI: 10.1002/1096-9861(20001204)428:1<20::AID-CNE3>3.0.CO;2-X  0.426
1999 Lövblad KO, Thomas R, Jakob PM, Scammell T, Bassetti C, Griswold M, Ives J, Matheson J, Edelman RR, Warach S. Silent functional magnetic resonance imaging demonstrates focal activation in rapid eye movement sleep. Neurology. 53: 2193-5. PMID 10599807 DOI: 10.1212/Wnl.53.9.2193  0.427
1999 Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell. 98: 437-51. PMID 10481909 DOI: 10.1016/S0092-8674(00)81973-X  0.644
1998 Scammell TE, Griffin JD, Elmquist JK, Saper CB. Microinjection of a cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 274: R783-R789. PMID 29586927 DOI: 10.1152/ajpregu.1998.274.3.R783  0.39
1998 Scammell TE, Matheson J. Modafinil: a novel stimulant for the treatment of narcolepsy. Expert Opinion On Investigational Drugs. 7: 99-112. PMID 15991923 DOI: 10.1517/13543784.7.1.99  0.313
1998 Scammell T, Gerashchenko D, Urade Y, Onoe H, Saper C, Hayaishi O. Activation of ventrolateral preoptic neurons by the somnogen prostaglandin D2. Proceedings of the National Academy of Sciences of the United States of America. 95: 7754-9. PMID 9636223 DOI: 10.1073/pnas.95.13.7754  0.654
1998 Scammell TE, Griffin JD, Elmquist JK, Saper CB. Microinjection of a cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever. The American Journal of Physiology. 274: R783-9. PMID 9530246 DOI: 10.1152/Ajpregu.1998.274.3.R783  0.389
1998 Gerashchenko D, Scammell T, Onoe H, Urade Y, Saper C, Hayaishi O. The somnogen PGD2 induces FOS expression within unique populations of sleep-active neurons Neuroscience Research. 31: S221. DOI: 10.1016/S0168-0102(98)82317-1  0.633
1997 Elmquist JK, Scammell TE, Saper CB. Mechanisms of CNS response to systemic immune challenge: the febrile response. Trends in Neurosciences. 20: 565-70. PMID 9416669 DOI: 10.1016/S0166-2236(97)01138-7  0.387
1997 Elmquist JK, Breder CD, Sherin JE, Scammell TE, Hickey WF, Dewitt D, Saper CB. Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages. The Journal of Comparative Neurology. 381: 119-29. PMID 9130663 DOI: 10.1002/(SICI)1096-9861(19970505)381:2<119::AID-CNE1>3.0.CO;2-6  0.445
1996 Elmquist JK, Scammell TE, Jacobson CD, Saper CB. Distribution of Fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration. The Journal of Comparative Neurology. 371: 85-103. PMID 8835720 DOI: 10.1002/(SICI)1096-9861(19960715)371:1<85::AID-CNE5>3.0.CO;2-H  0.431
1996 Scammell TE, Elmquist JK, Griffin JD, Saper CB. Ventromedial preoptic prostaglandin E2 activates fever-producing autonomic pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6246-54. PMID 8815905 DOI: 10.1523/Jneurosci.16-19-06246.1996  0.433
1996 Scammell TE, Elmquist JK, Saper CB. Inhibition of nitric oxide synthase produces hypothermia and depresses lipopolysaccharide fever. The American Journal of Physiology. 271: R333-8. PMID 8770131 DOI: 10.1152/Ajpregu.1996.271.2.R333  0.37
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