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Michael Min-Shyue Lai - Publications

Affiliations: 
2001 Johns Hopkins University, Baltimore, MD 
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Chen CL, Huang JY, Wang CH, Tahara SM, Zhou L, Kondo Y, Schechter J, Su L, Lai MM, Wakita T, Cosset FL, Jung JU, Machida K. Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2. Nature Communications. 8: 13882. PMID 28067225 DOI: 10.1038/Ncomms13882  0.302
2014 Lai CK, Saxena V, Tseng CH, Jeng KS, Kohara M, Lai MM. Nonstructural protein 5A is incorporated into hepatitis C virus low-density particle through interaction with core protein and microtubules during intracellular transport. Plos One. 9: e99022. PMID 24905011 DOI: 10.1371/Journal.Pone.0099022  0.307
2012 Liu Z, Tian Y, Machida K, Lai MM, Luo G, Foung SK, Ou JH. Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry. The Journal of Biological Chemistry. 287: 41922-30. PMID 23095753 DOI: 10.1074/Jbc.M112.414789  0.303
2012 Liu HM, Aizaki H, Machida K, Ou JH, Lai MM. Hepatitis C virus translation preferentially depends on active RNA replication. Plos One. 7: e43600. PMID 22937067 DOI: 10.1371/Journal.Pone.0043600  0.336
2012 Saxena V, Lai CK, Chao TC, Jeng KS, Lai MM. Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft. Journal of Virology. 86: 4139-50. PMID 22301157 DOI: 10.1128/Jvi.06327-11  0.32
2012 Chao TC, Su WC, Huang JY, Chen YC, Jeng KS, Wang HD, Lai MM. Proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2), a host membrane-deforming protein, is critical for membranous web formation in hepatitis C virus replication. Journal of Virology. 86: 1739-49. PMID 22130530 DOI: 10.1128/Jvi.06001-11  0.318
2011 Su WC, Chao TC, Huang YL, Weng SC, Jeng KS, Lai MM. Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy. Journal of Virology. 85: 10561-71. PMID 21835792 DOI: 10.1128/Jvi.00173-11  0.314
2011 Wang L, Jeng KS, Lai MM. Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral genome. Journal of Virology. 85: 7954-64. PMID 21632751 DOI: 10.1128/Jvi.00339-11  0.343
2010 Machida K, McNamara G, Cheng KT, Huang J, Wang CH, Comai L, Ou JH, Lai MM. Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes. Journal of Immunology (Baltimore, Md. : 1950). 185: 6985-98. PMID 20974981 DOI: 10.4049/Jimmunol.1000618  0.305
2010 Lai CK, Jeng KS, Machida K, Lai MM. Hepatitis C virus egress and release depend on endosomal trafficking of core protein. Journal of Virology. 84: 11590-8. PMID 20739534 DOI: 10.1128/Jvi.00587-10  0.321
2010 Chen YC, Su WC, Huang JY, Chao TC, Jeng KS, Machida K, Lai MM. Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A. Journal of Virology. 84: 7983-93. PMID 20534861 DOI: 10.1128/Jvi.00068-10  0.352
2009 Machida K, Liu JC, McNamara G, Levine A, Duan L, Lai MM. Hepatitis C virus causes uncoupling of mitotic checkpoint and chromosomal polyploidy through the Rb pathway. Journal of Virology. 83: 12590-600. PMID 19793824 DOI: 10.1128/Jvi.02643-08  0.335
2009 Hara H, Aizaki H, Matsuda M, Shinkai-Ouchi F, Inoue Y, Murakami K, Shoji I, Kawakami H, Matsuura Y, Lai MM, Miyamura T, Wakita T, Suzuki T. Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein. Journal of Virology. 83: 5137-47. PMID 19264780 DOI: 10.1128/Jvi.02179-08  0.352
2009 Liu HM, Aizaki H, Choi KS, Machida K, Ou JJ, Lai MM. SYNCRIP (synaptotagmin-binding, cytoplasmic RNA-interacting protein) is a host factor involved in hepatitis C virus RNA replication. Virology. 386: 249-56. PMID 19232660 DOI: 10.1016/J.Virol.2009.01.018  0.351
2008 Lai CK, Jeng KS, Machida K, Lai MM. Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A. Journal of Virology. 82: 8838-48. PMID 18562541 DOI: 10.1128/JVI.00398-08  0.321
2008 Aizaki H, Morikawa K, Fukasawa M, Hara H, Inoue Y, Tani H, Saito K, Nishijima M, Hanada K, Matsuura Y, Lai MM, Miyamura T, Wakita T, Suzuki T. Critical role of virion-associated cholesterol and sphingolipid in hepatitis C virus infection. Journal of Virology. 82: 5715-24. PMID 18367533 DOI: 10.1128/Jvi.02530-07  0.307
2006 Choi J, Forman HJ, Ou JH, Lai MM, Seronello S, Nandipati A. Redox modulation of the hepatitis C virus replication complex is calcium dependent. Free Radical Biology & Medicine. 41: 1488-98. PMID 17023276 DOI: 10.1016/J.Freeradbiomed.2006.08.008  0.314
2006 Yu GY, Lee KJ, Gao L, Lai MM. Palmitoylation and polymerization of hepatitis C virus NS4B protein. Journal of Virology. 80: 6013-23. PMID 16731940 DOI: 10.1128/Jvi.00053-06  0.345
2006 Aizaki H, Choi KS, Liu M, Li YJ, Lai MM. Polypyrimidine-tract-binding protein is a component of the HCV RNA replication complex and necessary for RNA synthesis. Journal of Biomedical Science. 13: 469-80. PMID 16691359 DOI: 10.1007/S11373-006-9088-4  0.339
2005 Hamamoto I, Nishimura Y, Okamoto T, Aizaki H, Liu M, Mori Y, Abe T, Suzuki T, Lai MM, Miyamura T, Moriishi K, Matsuura Y. Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B. Journal of Virology. 79: 13473-82. PMID 16227268 DOI: 10.1128/Jvi.79.21.13473-13482.2005  0.353
2004 Vo NV, Tuler JR, Lai MM. Enzymatic characterization of the full-length and C-terminally truncated hepatitis C virus RNA polymerases: function of the last 21 amino acids of the C terminus in template binding and RNA synthesis. Biochemistry. 43: 10579-91. PMID 15301555 DOI: 10.1021/Bi049773G  0.305
2004 Machida K, Cheng KT, Sung VM, Lee KJ, Levine AM, Lai MM. Hepatitis C virus infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby enhances DNA damage and mutations of cellular genes. Journal of Virology. 78: 8835-43. PMID 15280491 DOI: 10.1128/Jvi.78.16.8835-8843.2004  0.32
2004 Aizaki H, Lee KJ, Sung VM, Ishiko H, Lai MM. Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts. Virology. 324: 450-61. PMID 15207630 DOI: 10.1016/J.Virol.2004.03.034  0.339
2004 Lee KJ, Choi J, Ou JH, Lai MM. The C-terminal transmembrane domain of hepatitis C virus (HCV) RNA polymerase is essential for HCV replication in vivo. Journal of Virology. 78: 3797-802. PMID 15016899 DOI: 10.1128/Jvi.78.7.3797-3802.2004  0.35
2004 Gao L, Aizaki H, He JW, Lai MM. Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft. Journal of Virology. 78: 3480-8. PMID 15016871 DOI: 10.1128/Jvi.78.7.3480-3488.2004  0.321
2004 Machida K, Cheng KT, Sung VM, Shimodaira S, Lindsay KL, Levine AM, Lai MY, Lai MM. Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes. Proceedings of the National Academy of Sciences of the United States of America. 101: 4262-7. PMID 14999097 DOI: 10.1073/Pnas.0303971101  0.31
2004 Choi J, Lee KJ, Zheng Y, Yamaga AK, Lai MM, Ou JH. Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells. Hepatology (Baltimore, Md.). 39: 81-9. PMID 14752826 DOI: 10.1002/Hep.20001  0.356
2003 Young KC, Lindsay KL, Lee KJ, Liu WC, He JW, Milstein SL, Lai MM. Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy. Hepatology (Baltimore, Md.). 38: 869-78. PMID 14512874 DOI: 10.1002/Hep.1840380413  0.334
2003 Pavio N, Lai MM. The hepatitis C virus persistence: how to evade the immune system? Journal of Biosciences. 28: 287-304. PMID 12734407 DOI: 10.1007/Bf02970148  0.304
2003 Shi ST, Lee KJ, Aizaki H, Hwang SB, Lai MM. Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that cofractionates with caveolin-2. Journal of Virology. 77: 4160-8. PMID 12634374 DOI: 10.1128/Jvi.77.7.4160-4168.2003  0.336
2003 Gao L, Tu H, Shi ST, Lee KJ, Asanaka M, Hwang SB, Lai MM. Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase. Journal of Virology. 77: 4149-59. PMID 12634373 DOI: 10.1128/Jvi.77.7.4149-4159.2003  0.344
2003 Sung VM, Shimodaira S, Doughty AL, Picchio GR, Can H, Yen TS, Lindsay KL, Levine AM, Lai MM. Establishment of B-cell lymphoma cell lines persistently infected with hepatitis C virus in vivo and in vitro: the apoptotic effects of virus infection. Journal of Virology. 77: 2134-46. PMID 12525648 DOI: 10.1128/Jvi.77.3.2134-2146.2003  0.34
2002 Choi KS, Huang Py, Lai MM. Polypyrimidine-tract-binding protein affects transcription but not translation of mouse hepatitis virus RNA. Virology. 303: 58-68. PMID 12482658 DOI: 10.1006/Viro.2002.1675  0.307
2002 Koev G, Duncan RF, Lai MM. Hepatitis C virus IRES-dependent translation is insensitive to an eIF2alpha-independent mechanism of inhibition by interferon in hepatocyte cell lines. Virology. 297: 195-202. PMID 12083818 DOI: 10.1006/Viro.2002.1455  0.348
2002 Liu ZX, Nishida H, He JW, Lai MM, Feng N, Dennert G. Hepatitis C virus genotype 1b core protein does not exert immunomodulatory effects on virus-induced cellular immunity. Journal of Virology. 76: 990-7. PMID 11773374 DOI: 10.1128/Jvi.76.3.990-997.2002  0.312
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