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Manu Rangachari - Publications

Affiliations: 
2013- Laval University, Ville de Québec, Québec, Canada 
Area:
multiple sclerosis, Tregs, sex differences, immunology
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Akbar I, Tang R, Baillargeon J, Roy AP, Doss PMIA, Zhu C, Kuchroo VK, Rangachari M. Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 37909848 DOI: 10.4049/jimmunol.2300526  0.401
2023 Fazazi MR, Ruda GF, Brennan PE, Rangachari M. The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system. Brain Research Bulletin. 202: 110748. PMID 37657612 DOI: 10.1016/j.brainresbull.2023.110748  0.451
2022 Balood M, Ahmadi M, Eichwald T, Ahmadi A, Majdoubi A, Roversi K, Roversi K, Lucido CT, Restaino AC, Huang S, Ji L, Huang KC, Semerena E, Thomas SC, Trevino AE, ... ... Rangachari M, et al. Nociceptor neurons affect cancer immunosurveillance. Nature. PMID 36323780 DOI: 10.1038/s41586-022-05374-w  0.501
2021 Zhu C, Dixon KO, Newcomer K, Gu G, Xiao S, Zaghouani S, Schramm MA, Wang C, Zhang H, Goto K, Christian E, Rangachari M, Rosenblatt-Rosen O, Okada H, Mak T, et al. Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion. Science Advances. 7. PMID 33931442 DOI: 10.1126/sciadv.abd2710  0.56
2021 Doss PMIA, Umair M, Baillargeon J, Fazazi R, Fudge N, Akbar I, Yeola AP, Williams JB, Leclercq M, Joly-Beauparlant C, Beauchemin P, Ruda GF, Alpaugh M, Anderson AC, Brennan PE, ... ... Rangachari M, et al. Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity. Cell Reports. 34: 108833. PMID 33691111 DOI: 10.1016/j.celrep.2021.108833  0.304
2020 Pradeep Yeola A, Akbar I, Baillargeon J, Mercy Ignatius Arokia Doss P, Paavilainen VO, Rangachari M. Protein translocation and retro-translocation across the endoplasmic reticulum are crucial to inflammatory effector CD4 T cell function. Cytokine. 129: 154944. PMID 32146280 DOI: 10.1016/j.cyto.2019.154944  0.518
2019 Yeola AP, Ignatius Arokia Doss PM, Baillargeon J, Akbar I, Mailhot B, Balood M, Talbot S, Anderson AC, Lacroix S, Rangachari M. Endogenous T Cell Receptor Rearrangement Represses Aggressive Central Nervous System Autoimmunity in a TcR-Transgenic Model on the Non-Obese Diabetic Background. Frontiers in Immunology. 10: 3115. PMID 32010149 DOI: 10.3389/Fimmu.2019.03115  0.523
2019 Tang R, Rangachari M, Kuchroo VK. Tim-3: A co-receptor with diverse roles in T cell exhaustion and tolerance. Seminars in Immunology. 42: 101302. PMID 31604535 DOI: 10.1016/J.Smim.2019.101302  0.571
2019 Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, ... ... Rangachari M, et al. Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature. PMID 31363232 DOI: 10.1038/S41586-019-1459-X  0.461
2018 Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, ... ... Rangachari M, et al. The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature. PMID 30405245 DOI: 10.1038/S41586-018-0701-2  0.561
2018 Paré A, Mailhot B, Lévesque SA, Juzwik C, Ignatius Arokia Doss PM, Lécuyer MA, Prat A, Rangachari M, Fournier A, Lacroix S. IL-1β enables CNS access to CCR2hi monocytes and the generation of pathogenic cells through GM-CSF released by CNS endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29358392 DOI: 10.1073/Pnas.1714948115  0.31
2015 Ignatius Arokia Doss PM, Roy AP, Wang A, Anderson AC, Rangachari M. The Non-Obese Diabetic Mouse Strain as a Model to Study CD8(+) T Cell Function in Relapsing and Progressive Multiple Sclerosis. Frontiers in Immunology. 6: 541. PMID 26557120 DOI: 10.3389/fimmu.2015.00541  0.478
2015 Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan DJ, Wu C, Rangachari M, Pertel T, Jin HT, Ahmed R, Anderson AC, Kuchroo VK. Corrigendum: An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nature Communications. 6: 7657. PMID 26153760 DOI: 10.1038/Ncomms8657  0.375
2015 Boivin N, Baillargeon J, Doss PM, Roy AP, Rangachari M. Interferon-β suppresses murine Th1 cell function in the absence of antigen-presenting cells. Plos One. 10: e0124802. PMID 25885435 DOI: 10.1371/journal.pone.0124802  0.387
2015 Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan DJ, Wu C, Rangachari M, Pertel T, Jin HT, Ahmed R, Anderson AC, Kuchroo VK. An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nature Communications. 6: 6072. PMID 25614966 DOI: 10.1038/Ncomms7072  0.424
2013 Rangachari M, Kuchroo VK. Using EAE to better understand principles of immune function and autoimmune pathology. Journal of Autoimmunity. 45: 31-9. PMID 23849779 DOI: 10.1016/J.Jaut.2013.06.008  0.502
2013 Wu C, Pot C, Apetoh L, Thalhamer T, Zhu B, Murugaiyan G, Xiao S, Lee Y, Rangachari M, Yosef N, Kuchroo VK. Metallothioneins negatively regulate IL-27-induced type 1 regulatory T-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 110: 7802-7. PMID 23630250 DOI: 10.1073/Pnas.1211776110  0.313
2012 Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield EA, Sobel RA, Okada H, McKinnon PJ, Mak TW, Addo MM, Anderson AC, et al. Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion. Nature Medicine. 18: 1394-400. PMID 22863785 DOI: 10.1038/Nm.2871  0.555
2012 Quintana FJ, Jin H, Burns EJ, Nadeau M, Yeste A, Kumar D, Rangachari M, Zhu C, Xiao S, Seavitt J, Georgopoulos K, Kuchroo VK. Aiolos promotes TH17 differentiation by directly silencing Il2 expression. Nature Immunology. 13: 770-7. PMID 22751139 DOI: 10.1038/Ni.2363  0.461
2010 Mengshol JA, Golden-Mason L, Arikawa T, Smith M, Niki T, McWilliams R, Randall JA, McMahan R, Zimmerman MA, Rangachari M, Dobrinskikh E, Busson P, Polyak SJ, Hirashima M, Rosen HR. A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. Plos One. 5: e9504. PMID 20209097 DOI: 10.1371/Journal.Pone.0009504  0.349
2007 Loeser S, Loser K, Bijker MS, Rangachari M, van der Burg SH, Wada T, Beissert S, Melief CJ, Penninger JM. Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells. The Journal of Experimental Medicine. 204: 879-91. PMID 17403934 DOI: 10.1084/Jem.20061699  0.502
2006 Rangachari M, Mauermann N, Marty RR, Dirnhofer S, Kurrer MO, Komnenovic V, Penninger JM, Eriksson U. T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17. The Journal of Experimental Medicine. 203: 2009-19. PMID 16880257 DOI: 10.1084/Jem.20052222  0.494
2004 Rangachari M, Penninger JM. Negative regulation of T cell receptor signals. Current Opinion in Pharmacology. 4: 415-22. PMID 15251138 DOI: 10.1016/J.Coph.2004.03.007  0.503
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