Olav B. Smeland - Publications

Affiliations: 
University of Oslo, Norway, Oslo, Oslo, Norway 

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Ueland T, Steen NE, Djurovic S, ... ... Smeland OB, et al. Unraveling the shared genetics of common epilepsies and general cognitive ability. Medrxiv : the Preprint Server For Health Sciences. PMID 38585944 DOI: 10.1101/2024.03.25.24304773  0.8
2024 Shadrin AA, Hindley G, Hagen E, Parker N, Tesfaye M, Jaholkowski P, Rahman Z, Kutrolli G, Fominykh V, Djurovic S, Smeland OB, O'Connell KS, van der Meer D, Frei O, Andreassen OA, et al. Dissecting the genetic overlap between three complex phenotypes with trivariate MiXeR. Medrxiv : the Preprint Server For Health Sciences. PMID 38464132 DOI: 10.1101/2024.02.23.24303236  0.751
2024 Hindley G, Drange OK, Lin A, Kutrolli G, Shadrin AA, Parker N, O'Connell KS, Rødevand L, Cheng W, Bahrami S, Karadag N, Holen B, Jaholkowski P, Woldeyohannes MT, Djurovic S, ... ... Smeland OB, et al. Corrigendum to "Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders" [Psychoneuroendocrinology 157 (2023) 106368]. Psychoneuroendocrinology. 106980. PMID 38336601 DOI: 10.1016/j.psyneuen.2024.106980  0.817
2024 Koch E, Kämpe A, Alver M, Sigurðarson S, Einarsson G, Partanen J, Smith RL, Jaholkowski P, Taipale H, Lähteenvuo M, Steen NE, Smeland OB, Djurovic S, Molden E, Sigurdsson E, et al. Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 38184734 DOI: 10.1038/s41386-023-01792-0  0.493
2023 Holen B, Kutrolli G, Shadrin AA, Icick R, Hindley G, Rødevand L, O'Connell KS, Frei O, Parker N, Tesfaye M, Deak JD, Jahołkowski P, Dale AM, Djurovic S, Andreassen OA, ... Smeland OB, et al. Genome-wide analyses reveal shared genetic architecture and novel risk loci between opioid use disorder and general cognitive ability. Drug and Alcohol Dependence. 256: 111058. PMID 38244365 DOI: 10.1016/j.drugalcdep.2023.111058  0.761
2023 Icick R, Shadrin A, Holen B, Karadag N, Parker N, O'Connell K, Frei O, Bahrami S, Høegh M, Lagerberg T, Cheng W, Seibert T, Djurovic S, Dale A, Zhou H, ... ... Smeland O, et al. Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals. Research Square. PMID 38196616 DOI: 10.21203/rs.3.rs-3755915/v1  0.842
2023 Wootton O, Shadrin AA, Bjella T, Smeland OB, van der Meer D, Frei O, O'Connell KS, Ueland T, Andreassen OA, Stein DJ, Dalvie S. Genomic Insights into the Shared and Distinct Genetic Architecture of Cognitive Function and Schizophrenia. Medrxiv : the Preprint Server For Health Sciences. PMID 38014326 DOI: 10.1101/2023.11.13.23298348  0.715
2023 van der Meer D, Cheng W, Rokicki J, Fernandez-Cabello S, Shadrin A, Smeland OB, Ehrhart F, Gülöksüz S, Pries LK, Lin B, Rutten BPF, van Os J, O'Donovan M, Richards AL, Steen NE, et al. Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation. Schizophrenia Bulletin. PMID 37824720 DOI: 10.1093/schbul/sbad140  0.437
2023 Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, ... ... Smeland OB, et al. GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. The American Journal of Psychiatry. 180: 723-738. PMID 37777856 DOI: 10.1176/appi.ajp.21121266  0.492
2023 Parker N, Cheng W, Hindley GFL, Parekh P, Shadrin AA, Maximov II, Smeland OB, Djurovic S, Dale AM, Westlye LT, Frei O, Andreassen OA. Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology. Molecular Psychiatry. PMID 37759039 DOI: 10.1038/s41380-023-02264-z  0.792
2023 Rødevand L, Rahman Z, Hindley GFL, Smeland OB, Frei O, Tekin TF, Kutrolli G, Bahrami S, Hoseth EZ, Shadrin A, Lin A, Djurovic S, Dale AM, Steen NE, Andreassen OA. Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors. The American Journal of Psychiatry. appiajp20220660. PMID 37752828 DOI: 10.1176/appi.ajp.20220660  0.699
2023 Tesfaye M, Jaholkowski P, Shadrin AA, Hindley GFL, Holen B, Parker N, Parekh P, Rahman Z, Bahrami S, Kutrolli G, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, et al. Identification of Novel Genomic Loci for Anxiety and Extensive Genetic Overlap with Psychiatric Disorders. Medrxiv : the Preprint Server For Health Sciences. PMID 37693403 DOI: 10.1101/2023.09.01.23294920  0.759
2023 Akkouh IA, Ueland T, Szabo A, Hughes T, Smeland OB, Andreassen OA, Osete JR, Djurovic S. Longitudinal transcriptomic analysis of human cortical spheroids identifies axonal dysregulation in the prenatal brain as a mediator of genetic risk for schizophrenia. Biological Psychiatry. PMID 37661009 DOI: 10.1016/j.biopsych.2023.08.017  0.456
2023 Hindley G, Drange OK, Lin A, Kutrolli G, Shadrin AA, Parker N, O'Connell KS, Rødevand L, Cheng W, Bahrami S, Karadag N, Holen B, Jaholkowski P, Woldeyohannes MT, Djurovic S, ... ... Smeland OB, et al. Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders. Psychoneuroendocrinology. 157: 106368. PMID 37659117 DOI: 10.1016/j.psyneuen.2023.106368  0.863
2023 Bang L, Bahrami S, Hindley G, Smeland OB, Rødevand L, Jaholkowski PP, Shadrin A, Connell KSO, Frei O, Lin A, Rahman Z, Cheng W, Parker N, Fan CC, Dale AM, et al. Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa. Translational Psychiatry. 13: 291. PMID 37658054 DOI: 10.1038/s41398-023-02585-1  0.801
2023 Tesfaye M, Jaholkowski P, Hindley GFL, Shadrin AA, Rahman Z, Bahrami S, Lin A, Holen B, Parker N, Cheng W, Rødevand L, Frei O, Djurovic S, Dale AM, Smeland OB, et al. Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis. Genome Medicine. 15: 60. PMID 37528461 DOI: 10.1186/s13073-023-01212-4  0.798
2023 Smeland OB, Kutrolli G, Bahrami S, Fominykh V, Parker N, Hindley GFL, Rødevand L, Jaholkowski P, Tesfaye M, Parekh P, Elvsåshagen T, Grotzinger AD, Steen NE, van der Meer D, O'Connell KS, et al. Genome-wide analyses reveal widespread genetic overlap between neurological and psychiatric disorders and a convergence of biological associations related to the brain. Medrxiv : the Preprint Server For Health Sciences. PMID 37503175 DOI: 10.1101/2023.07.21.23292993  0.787
2023 Hindley G, Shadrin AA, van der Meer D, Parker N, Cheng W, O'Connell KS, Bahrami S, Lin A, Karadag N, Holen B, Bjella T, Deary IJ, Davies G, Hill WD, Bressler J, ... ... Smeland OB, et al. Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy. Nature Human Behaviour. PMID 37365406 DOI: 10.1038/s41562-023-01630-9  0.83
2023 Parker N, Cheng W, Hindley GFL, O'Connell KS, Karthikeyan S, Holen B, Shadrin AA, Rahman Z, Karadag N, Bahrami S, Lin A, Steen NE, Ueland T, Aukrust P, Djurovic S, ... ... Smeland OB, et al. Genetic Overlap between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts. Biological Psychiatry. PMID 37348803 DOI: 10.1016/j.biopsych.2023.06.008  0.808
2023 Steen NE, Rahman Z, Szabo A, Hindley GFL, Parker N, Cheng W, Lin A, O'Connell KS, Sheikh MA, Shadrin A, Bahrami S, Karthikeyan S, Hoseth EZ, Dale AM, Aukrust P, ... Smeland OB, et al. Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities. Schizophrenia Bulletin. PMID 37319439 DOI: 10.1093/schbul/sbad082  0.736
2023 Birkenæs V, Refsum Bakken N, Frei E, Jaholkowski P, Smeland OB, Tesfaye M, Agartz I, Susser E, Bresnahan M, Røysamb E, Nordbø Jørgensen K, Nesvåg R, Havdahl A, Andreassen OA, Elken Sønderby I. Psychometric Properties and Diagnostic Associations of the Short-Form Community Assessment of Psychic Experiences in a Population-Based Sample of 29 021 Adult Men. Schizophrenia Bulletin. PMID 37262330 DOI: 10.1093/schbul/sbad074  0.403
2023 Holen B, Shadrin AA, Icick R, Filiz TT, Hindley G, Rødevand L, O'Connell KS, Hagen E, Frei O, Bahrami S, Cheng W, Parker N, Tesfaye M, Jahołkowski P, Karadag N, ... ... Smeland OB, et al. Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression. Addiction Biology. 28: e13282. PMID 37252880 DOI: 10.1111/adb.13282  0.864
2023 Cheng W, Parker N, Karadag N, Koch E, Hindley G, Icick R, Shadrin A, O'Connell KS, Bjella T, Bahrami S, Rahman Z, Tesfaye M, Jaholkowski P, Rødevand L, Holen B, ... ... Smeland OB, et al. The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study. The Lancet. Psychiatry. 10: 441-451. PMID 37208114 DOI: 10.1016/S2215-0366(23)00143-8  0.848
2023 Jaholkowski P, Hindley GFL, Shadrin AA, Tesfaye M, Bahrami S, Nerhus M, Rahman Z, O'Connell KS, Holen B, Parker N, Cheng W, Lin A, Rødevand L, Karadag N, Frei O, ... ... Smeland OB, et al. Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci. Schizophrenia Bulletin. PMID 37163672 DOI: 10.1093/schbul/sbad063  0.85
2023 Jaholkowski P, Shadrin AA, Jangmo A, Frei E, Tesfaye M, Hindley GFL, Haram M, Rahman Z, Athanasiu L, Bakken NR, Holen B, Fominykh V, Kutrolli G, Parekh P, Parker N, ... ... Smeland OB, et al. Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders. Jama Psychiatry. PMID 37163253 DOI: 10.1001/jamapsychiatry.2023.1137  0.722
2023 O'Connell KS, Koch E, Lenk HÇ, Akkouh IA, Hindley G, Jaholkowski P, Smith RL, Holen B, Shadrin AA, Frei O, Smeland OB, Steen NE, Dale AM, Molden E, Djurovic S, et al. Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia. Psychiatry Research. 325: 115217. PMID 37146461 DOI: 10.1016/j.psychres.2023.115217  0.713
2023 Reas ET, Shadrin A, Frei O, Motazedi E, McEvoy L, Bahrami S, van der Meer D, Makowski C, Loughnan R, Wang X, Broce I, Banks SJ, Fominykh V, Cheng W, Holland D, ... Smeland OB, et al. Improved multimodal prediction of progression from MCI to Alzheimer's disease combining genetics with quantitative brain MRI and cognitive measures. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37132098 DOI: 10.1002/alz.13112  0.625
2023 Karadag N, Shadrin AA, O'Connell K, Hindley GFL, Rahman Z, Parker N, Bahrami S, Fominykh V, Cheng W, Holen B, Alvestad S, Taubøll E, Steen NE, Djurovic S, Dale AM, ... ... Smeland OB, et al. Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders. Brain : a Journal of Neurology. PMID 36757824 DOI: 10.1093/brain/awad038  0.851
2023 Osete JR, Akkouh IA, Ievglevskyi O, Vandenberghe M, de Assis DR, Ueland T, Kondratskaya E, Holen B, Szabo A, Hughes T, Smeland OB, Steen VM, Andreassen OA, Djurovic S. Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids. Molecular Psychiatry. PMID 36653674 DOI: 10.1038/s41380-023-01944-0  0.387
2023 Andreassen OA, Hindley GFL, Frei O, Smeland OB. New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 22: 4-24. PMID 36640404 DOI: 10.1002/wps.21034  0.789
2022 Cheng W, van der Meer D, Parker N, Hindley G, O'Connell KS, Wang Y, Shadrin AA, Alnæs D, Bahrami S, Lin A, Karadag N, Holen B, Fernandez-Cabello S, Fan CC, Dale AM, ... ... Smeland OB, et al. Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood. Molecular Psychiatry. PMID 36100668 DOI: 10.1038/s41380-022-01751-z  0.833
2022 Hindley G, Frei O, Shadrin AA, Cheng W, O'Connell KS, Icick R, Parker N, Bahrami S, Karadag N, Roelfs D, Holen B, Lin A, Fan CC, Djurovic S, Dale AM, ... Smeland OB, et al. Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation. The American Journal of Psychiatry. appiajp21101051. PMID 36069018 DOI: 10.1176/appi.ajp.21101051  0.853
2022 Icick R, Shadrin A, Holen B, Karadag N, Lin A, Hindley G, O'Connell K, Frei O, Bahrami S, Høegh MC, Cheng W, Fan CC, Djurovic S, Dale AM, Lagerberg TV, ... Smeland OB, et al. Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35953530 DOI: 10.1038/s41386-022-01401-6  0.834
2022 Hindley G, O'Connell KS, Rahman Z, Frei O, Bahrami S, Shadrin A, Høegh MC, Cheng W, Karadag N, Lin A, Rødevand L, Fan CC, Djurovic S, Lagerberg TV, Dale AM, ... Smeland OB, et al. The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 35841185 DOI: 10.1002/ajmg.b.32907  0.85
2022 Torgersen K, Rahman Z, Bahrami S, Hindley GFL, Parker N, Frei O, Shadrin A, O'Connell KS, Tesli M, Smeland OB, Munkhaugen J, Djurovic S, Dammen T, Andreassen OA. Shared genetic loci between depression and cardiometabolic traits. Plos Genetics. 18: e1010161. PMID 35560157 DOI: 10.1371/journal.pgen.1010161  0.647
2022 Streit F, Witt SH, Awasthi S, Foo JC, Jungkunz M, Frank J, Colodro-Conde L, Hindley G, Smeland OB, Maslahati T, Schwarze CE, Dahmen N, Schott BH, Kleindienst N, Hartmann A, et al. Borderline personality disorder and the big five: molecular genetic analyses indicate shared genetic architecture with neuroticism and openness. Translational Psychiatry. 12: 153. PMID 35411043 DOI: 10.1038/s41398-022-01912-2  0.566
2022 Van Assche E, Schulte EC, Andreassen OA, Smeland OB, Luykx JJ. Editorial: Cross-disorder Genetics in Neuropsychiatry. Frontiers in Neuroscience. 16: 826300. PMID 35221906 DOI: 10.3389/fnins.2022.826300  0.577
2022 van der Meer D, Shadrin AA, O'Connell K, Bettella F, Djurovic S, Wolfers T, Alnæs D, Agartz I, Smeland OB, Melle I, Sánchez JM, Linden DEJ, Dale AM, Westlye LT, Andreassen OA, et al. Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology. Biological Psychiatry. PMID 35164939 DOI: 10.1016/j.biopsych.2021.12.007  0.746
2022 Smeland OB, Andreassen OA. Schizophrenia: genetic insights with clinical potential. Nature Reviews. Neurology. PMID 34987233 DOI: 10.1038/s41582-021-00613-6  0.503
2021 Kalman JL, Olde Loohuis LM, Vreeker A, McQuillin A, Stahl EA, Ruderfer D, Grigoroiu-Serbanescu M, Panagiotaropoulou G, Ripke S, Bigdeli TB, Stein F, Meller T, Meinert S, Pelin H, Streit F, ... ... Smeland OB, et al. Characterisation of age and polarity at onset in bipolar disorder. The British Journal of Psychiatry : the Journal of Mental Science. 219: 659-669. PMID 35048876 DOI: 10.1192/bjp.2021.102  0.495
2021 Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, ... ... Smeland OB, et al. Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biological Psychiatry. PMID 34861974 DOI: 10.1016/j.biopsych.2021.05.029  0.506
2021 Szabo A, Akkouh IA, Vandenberghe M, Osete JR, Hughes T, Heine V, Smeland OB, Glover JC, Andreassen OA, Djurovic S. A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia. Translational Psychiatry. 11: 554. PMID 34716291 DOI: 10.1038/s41398-021-01681-4  0.361
2021 Shadrin AA, Kaufmann T, van der Meer D, Palmer CE, Makowski C, Loughnan R, Jernigan TL, Seibert TM, Hagler DJ, Smeland OB, Motazedi E, Chu Y, Lin A, Cheng W, Hindley G, et al. Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology. Neuroimage. 118603. PMID 34560273 DOI: 10.1016/j.neuroimage.2021.118603  0.731
2021 Hindley G, Bahrami S, Steen NE, O'Connell KS, Frei O, Shadrin A, Bettella F, Rødevand L, Fan CC, Dale AM, Djurovic S, Smeland OB, Andreassen OA. Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking. Translational Psychiatry. 11: 466. PMID 34497263 DOI: 10.1038/s41398-021-01576-4  0.748
2021 O'Connell KS, Frei O, Bahrami S, Smeland OB, Bettella F, Cheng W, Chu Y, Hindley G, Lin A, Shadrin A, Barrett EA, Lagerberg TV, Steen NE, Dale AM, Djurovic S, et al. Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes. Biological Psychiatry. PMID 34482950 DOI: 10.1016/j.biopsych.2021.07.007  0.744
2021 Wiström ED, O'Connell KS, Karadag N, Bahrami S, Hindley GFL, Lin A, Cheng W, Steen NE, Shadrin A, Frei O, Djurovic S, Dale AM, Andreassen OA, Smeland OB. Genome-wide analysis reveals genetic overlap between alcohol use behaviors, schizophrenia and bipolar disorder and identifies novel shared risk loci. Addiction (Abingdon, England). PMID 34472679 DOI: 10.1111/add.15680  0.84
2021 Krull F, Akkouh I, Hughes T, Bettella F, Athanasiu L, Smeland OB, O'Connell KS, Brattbakk HR, Steen VM, Steen NE, Djurovic S, Andreassen OA. Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110408. PMID 34320404 DOI: 10.1016/j.pnpbp.2021.110408  0.384
2021 Rødevand L, Bahrami S, Frei O, Chu Y, Shadrin A, O'Connell KS, Smeland OB, Elvsåshagen T, Hindley GFL, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA. Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes. Translational Psychiatry. 11: 407. PMID 34301917 DOI: 10.1038/s41398-021-01527-z  0.75
2021 Monereo-Sánchez J, Schram MT, Frei O, O'Connell K, Shadrin AA, Smeland OB, Westlye LT, Andreassen OA, Kaufmann T, Linden DEJ, van der Meer D. Genetic Overlap Between Alzheimer's Disease and Depression Mapped Onto the Brain. Frontiers in Neuroscience. 15: 653130. PMID 34290577 DOI: 10.3389/fnins.2021.653130  0.739
2021 Bahrami S, Hindley G, Winsvold BS, O'Connell KS, Frei O, Shadrin A, Cheng W, Bettella F, Rødevand L, Odegaard KJ, Fan CC, Pirinen MJ, Hautakangas HM, Headache HA, Dale AM, ... ... Smeland OB, et al. Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools. Brain : a Journal of Neurology. PMID 34273149 DOI: 10.1093/brain/awab267  0.758
2021 Torgersen K, Bahrami S, Frei O, Shadrin A, Connell KSO, Smeland OB, Munkhaugen J, Djurovic S, Dammen T, Andreassen OA. Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors. Translational Psychiatry. 11: 368. PMID 34226488 DOI: 10.1038/s41398-021-01466-9  0.675
2021 Holland D, Frei O, Desikan R, Fan CC, Shadrin AA, Smeland OB, Andreassen OA, Dale AM. Erratum to: The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity. Genetics. 218. PMID 34167151 DOI: 10.1093/genetics/iyab064  0.695
2021 Cheng W, Frei O, van der Meer D, Wang Y, O'Connell KS, Chu Y, Bahrami S, Shadrin AA, Alnæs D, Hindley GFL, Lin A, Karadag N, Fan CC, Westlye LT, Kaufmann T, ... ... Smeland OB, et al. Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness. Jama Psychiatry. PMID 34160554 DOI: 10.1001/jamapsychiatry.2021.1435  0.832
2021 Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R, St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, ... ... Smeland OB, et al. Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry. PMID 34099189 DOI: 10.1016/j.biopsych.2021.02.972  0.611
2021 Osete JR, Akkouh IA, de Assis DR, Szabo A, Frei E, Hughes T, Smeland OB, Steen NE, Andreassen OA, Djurovic S. Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders. Molecular Psychiatry. PMID 34075196 DOI: 10.1038/s41380-021-01164-4  0.367
2021 Gurholt TP, Kaufmann T, Frei O, Alnæs D, Haukvik UK, van der Meer D, Moberget T, O'Connell KS, Leinhard OD, Linge J, Simon R, Smeland OB, Sønderby IE, Winterton A, Steen NE, et al. Population-based body-brain mapping links brain morphology with anthropometrics and body composition. Translational Psychiatry. 11: 295. PMID 34006848 DOI: 10.1038/s41398-021-01414-7  0.645
2021 Elvsåshagen T, Shadrin A, Frei O, van der Meer D, Bahrami S, Kumar VJ, Smeland O, Westlye LT, Andreassen OA, Kaufmann T. The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Nature Communications. 12: 2909. PMID 34006833 DOI: 10.1038/s41467-021-23175-z  0.764
2021 Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, ... ... Smeland OB, et al. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics. PMID 34002096 DOI: 10.1038/s41588-021-00857-4  0.745
2021 Roelfs D, Alnæs D, Frei O, van der Meer D, Smeland OB, Andreassen OA, Westlye LT, Kaufmann T. Phenotypically independent profiles relevant to mental health are genetically correlated. Translational Psychiatry. 11: 202. PMID 33795632 DOI: 10.1038/s41398-021-01313-x  0.754
2021 Holland D, Frei O, Desikan R, Fan CC, Shadrin AA, Smeland OB, Andreassen OA, Dale AM. The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity. Genetics. 217. PMID 33789345 DOI: 10.1093/genetics/iyaa046  0.673
2021 O'Connell KS, Sønderby IE, Frei O, van der Meer D, Athanasiu L, Smeland OB, Alnæs D, Kaufmann T, Westlye LT, Steen VM, Andreassen OA, Hughes T, Djurovic S. Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank. Psychological Medicine. 1-11. PMID 33653435 DOI: 10.1017/S0033291721000179  0.608
2021 Bahrami S, Shadrin A, Frei O, O'Connell KS, Bettella F, Krull F, Fan CC, Røssberg JI, Hindley G, Ueland T, Dale AM, Djurovic S, Steen NE, Smeland OB, Andreassen OA. Genetic loci shared between major depression and intelligence with mixed directions of effect. Nature Human Behaviour. PMID 33462475 DOI: 10.1038/s41562-020-01031-2  0.755
2021 Rødevand L, Bahrami S, Frei O, Lin A, Gani O, Shadrin A, Smeland OB, Connell KSO, Elvsåshagen T, Winterton A, Quintana DS, Hindley GFL, Werner MCF, Djurovic S, Dale AM, et al. Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms. Translational Psychiatry. 11: 3. PMID 33414458 DOI: 10.1038/s41398-020-01142-4  0.753
2020 Engen MJ, Lyngstad SH, Ueland T, Simonsen CE, Vaskinn A, Smeland O, Bettella F, Lagerberg TV, Djurovic S, Andreassen OA, Melle I. Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls. Translational Psychiatry. 10: 416. PMID 33257657 DOI: 10.1038/s41398-020-01094-9  0.465
2020 van der Meer D, Frei O, Kaufmann T, Shadrin AA, Devor A, Smeland OB, Thompson WK, Fan CC, Holland D, Westlye LT, Andreassen OA, Dale AM. Author Correction: Understanding the genetic determinants of the brain with MOSTest. Nature Communications. 11: 4700. PMID 32929091 DOI: 10.1038/S41467-020-18628-W  0.681
2020 van der Meer D, Frei O, Kaufmann T, Shadrin AA, Devor A, Smeland OB, Thompson WK, Fan CC, Holland D, Westlye LT, Andreassen OA, Dale AM. Understanding the genetic determinants of the brain with MOSTest. Nature Communications. 11: 3512. PMID 32665545 DOI: 10.1038/S41467-020-17368-1  0.724
2020 Shadrin AA, Frei O, Smeland OB, Bettella F, O Connell KS, Gani O, Bahrami S, Uggen TKE, Djurovic S, Holland D, Andreassen OA, Dale AM. Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR. Bioinformatics (Oxford, England). PMID 32539089 DOI: 10.1093/bioinformatics/btaa568  0.717
2020 Manchia M, Vieta E, Smeland OB, Altimus C, Bechdolf A, Bellivier F, Bergink V, Fagiolini A, Geddes JR, Hajek T, Henry C, Kupka R, Lagerberg TV, Licht RW, Martinez-Cengotitabengoa M, et al. Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 32536571 DOI: 10.1016/J.Euroneuro.2020.05.006  0.442
2020 Smeland OB, Frei O, Dale AM, Andreassen OA. The polygenic architecture of schizophrenia - rethinking pathogenesis and nosology. Nature Reviews. Neurology. 16: 366-379. PMID 32528109 DOI: 10.1038/s41582-020-0364-0  0.721
2020 Holland D, Frei O, Desikan R, Fan CC, Shadrin AA, Smeland OB, Sundar VS, Thompson P, Andreassen OA, Dale AM. Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model. Plos Genetics. 16: e1008612. PMID 32427991 DOI: 10.1371/Journal.Pgen.1008612  0.65
2020 Smeland OB, Shadrin A, Bahrami S, Broce I, Tesli M, Frei O, Wirgenes KV, O'Connell KS, Krull F, Bettella F, Steen NE, Sugrue L, Wang Y, Svenningsson P, Sharma M, et al. Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci. Biological Psychiatry. PMID 32201043 DOI: 10.1016/J.Biopsych.2020.01.026  0.762
2020 Córdova-Palomera A, van der Meer D, Kaufmann T, Bettella F, Wang Y, Alnæs D, Doan NT, Agartz I, Bertolino A, Buitelaar JK, Coynel D, Djurovic S, Dørum ES, Espeseth T, Fazio L, ... ... Smeland OB, et al. Genetic control of variability in subcortical and intracranial volumes. Molecular Psychiatry. PMID 32047264 DOI: 10.1038/S41380-020-0664-1  0.722
2020 Bahrami S, Steen NE, Shadrin A, O'Connell K, Frei O, Bettella F, Wirgenes KV, Krull F, Fan CC, Dale AM, Smeland OB, Djurovic S, Andreassen OA. Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study. Jama Psychiatry. PMID 31913414 DOI: 10.1001/jamapsychiatry.2019.4188  0.763
2019 O'Connell KS, Shadrin A, Smeland OB, Bahrami S, Frei O, Bettella F, Krull F, Fan CC, Askeland RB, Knudsen GPS, Halmøy A, Steen NE, Ueland T, Walters GB, Davíðsdóttir K, et al. Identification of Genetic Loci Shared Between Attention-Deficit/Hyperactivity Disorder, Intelligence, and Educational Attainment. Biological Psychiatry. PMID 32061372 DOI: 10.1016/j.biopsych.2019.11.015  0.721
2019 Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, ... ... Smeland OB, et al. Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience. PMID 31848485 DOI: 10.1038/S41593-019-0553-6  0.662
2019 O'Connell KS, Shadrin A, Bahrami S, Smeland OB, Bettella F, Frei O, Krull F, Askeland RB, Walters GB, Davíðsdóttir K, Haraldsdóttir GS, Guðmundsson ÓÓ, Stefánsson H, Fan CC, Steen NE, et al. Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder. Molecular Psychiatry. PMID 31792363 DOI: 10.1038/s41380-019-0613-z  0.732
2019 Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, ... ... Smeland OB, et al. Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience. 22: 1617-1623. PMID 31551603 DOI: 10.1038/s41593-019-0471-7  0.683
2019 Smeland OB, Frei O, Shadrin A, O'Connell K, Fan CC, Bahrami S, Holland D, Djurovic S, Thompson WK, Dale AM, Andreassen OA. Discovery of shared genomic loci using the conditional false discovery rate approach. Human Genetics. PMID 31520123 DOI: 10.1007/s00439-019-02060-2  0.761
2019 Smeland OB, Frei O, Fan CC, Shadrin A, Dale AM, Andreassen OA. The emerging pattern of shared polygenic architecture of psychiatric disorders, conceptual and methodological challenges. Psychiatric Genetics. 29: 152-159. PMID 31464996 DOI: 10.1097/YPG.0000000000000234  0.799
2019 Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA. Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence. Molecular Psychiatry. PMID 31308466 DOI: 10.1038/S41380-019-0456-7  0.758
2019 Mullins N, Bigdeli TB, Børglum AD, Coleman JRI, Demontis D, Mehta D, Power RA, Ripke S, Stahl EA, Starnawska A, Anjorin A, Corvin A, Sanders AR, Forstner AJ, ... ... Smeland OB, et al. GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. The American Journal of Psychiatry. appiajp201918080957. PMID 31164008 DOI: 10.1176/Appi.Ajp.2019.18080957  0.532
2019 Frei O, Holland D, Smeland OB, Shadrin AA, Fan CC, Maeland S, O'Connell KS, Wang Y, Djurovic S, Thompson WK, Andreassen OA, Dale AM. Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation. Nature Communications. 10: 2417. PMID 31160569 DOI: 10.1038/s41467-019-10310-0  0.782
2019 Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, ... ... Smeland OB, et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics. PMID 31043756 DOI: 10.1038/S41588-019-0397-8  0.602
2019 Alnæs D, Kaufmann T, van der Meer D, Córdova-Palomera A, Rokicki J, Moberget T, Bettella F, Agartz I, Barch DM, Bertolino A, Brandt CL, Cervenka S, Djurovic S, Doan NT, Eisenacher S, ... ... Smeland OB, et al. Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk. Jama Psychiatry. PMID 30969333 DOI: 10.1001/jamapsychiatry.2019.0257  0.471
2019 Drange OK, Smeland OB, Shadrin AA, Finseth PI, Witoelar A, Frei O, Wang Y, Hassani S, Djurovic S, Dale AM, Andreassen OA. Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes. Frontiers in Neuroscience. 13: 220. PMID 30930738 DOI: 10.3389/Fnins.2019.00220  0.733
2019 Steen NE, Dieset I, Hope S, Vedal TSJ, Smeland OB, Matson W, Kaddurah-Daouk R, Agartz I, Melle I, Djurovic S, Jönsson EG, Bogdanov M, Andreassen OA. Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders. Psychological Medicine. 1-12. PMID 30867076 DOI: 10.1017/S0033291719000400  0.443
2019 Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA. Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence. Molecular Psychiatry. PMID 30610197 DOI: 10.1038/S41380-018-0332-X  0.775
2018 van der Meer D, Rokicki J, Kaufmann T, Córdova-Palomera A, Moberget T, Alnæs D, Bettella F, Frei O, Doan NT, Sønderby IE, Smeland OB, Agartz I, Bertolino A, Bralten J, Brandt CL, et al. Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Molecular Psychiatry. PMID 30279459 DOI: 10.1038/S41380-018-0262-7  0.744
2018 Bettella F, Brown AA, Smeland OB, Wang Y, Witoelar A, Buil Demur AA, Thompson WK, Zuber V, Dale AM, Djurovic S, Andreassen OA. Cross-tissue eQTL enrichment of associations in schizophrenia. Plos One. 13: e0202812. PMID 30188921 DOI: 10.1371/Journal.Pone.0202812  0.437
2018 Srinivasan S, Bettella F, Frei O, Hill WD, Wang Y, Witoelar A, Schork AJ, Thompson WK, Davies G, Desikan RS, Deary IJ, Melle I, Ueland T, Dale AM, Djurovic S, ... Smeland OB, et al. Enrichment of genetic markers of recent human evolution in educational and cognitive traits. Scientific Reports. 8: 12585. PMID 30135563 DOI: 10.1038/S41598-018-30387-9  0.706
2018 Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, de Leeuw CA, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski JA, Karlsson R, Krapohl E, ... ... Smeland OB, et al. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics. PMID 29942086 DOI: 10.1038/S41588-018-0152-6  0.608
2018 Karch CM, Wen N, Fan CC, Yokoyama JS, Kouri N, Ross OA, Höglinger G, Müller U, Ferrari R, Hardy J, Schellenberg GD, Sleiman PM, Momeni P, Hess CP, Miller BL, ... ... Smeland OB, et al. Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum. Jama Neurology. PMID 29630712 DOI: 10.1001/Jamaneurol.2018.0372  0.499
2018 Fan CC, Smeland OB, Schork AJ, Chen CH, Holland D, Lo MT, Velkur S, Frei O, Jernigan TL, Andreassen OA, Dale AM. Beyond heritability: Improving discoverability in imaging genetics. Human Molecular Genetics. PMID 29522091 DOI: 10.1093/Hmg/Ddy082  0.738
2018 Shadrin AA, Smeland OB, Zayats T, Schork AJ, Frei O, Bettella F, Witoelar A, Li W, Eriksen JA, Krull F, Djurovic S, Faraone SV, Reichborn-Kjennerud T, Thompson WK, Johansson S, et al. Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment. Journal of the American Academy of Child and Adolescent Psychiatry. 57: 86-95. PMID 29413154 DOI: 10.1016/J.Jaac.2017.11.013  0.69
2018 Smeland OB, Andreassen OA. How can genetics help understand the relationship between cognitive dysfunction and schizophrenia? Scandinavian Journal of Psychology. 59: 26-31. PMID 29356008 DOI: 10.1111/sjop.12407  0.534
2018 Zuber V, Jönsson EG, Frei O, Witoelar A, Thompson WK, Schork AJ, Bettella F, Wang Y, Djurovic S, Smeland OB, Dieset I, Fanous AH, Desikan RS, Küry S, Bézieau S, et al. Identification of shared genetic variants between schizophrenia and lung cancer. Scientific Reports. 8: 674. PMID 29330379 DOI: 10.1038/S41598-017-16481-4  0.704
2017 Chen CH, Wang Y, Lo MT, Schork A, Fan CC, Holland D, Kauppi K, Smeland OB, Djurovic S, Sanyal N, Hibar DP, Thompson PM, Thompson WK, Andreassen OA, Dale AM. Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure. Scientific Reports. 7: 15736. PMID 29147026 DOI: 10.1038/S41598-017-15705-X  0.486
2017 Smeland OB, Wang Y, Frei O, Li W, Hibar DP, Franke B, Bettella F, Witoelar A, Djurovic S, Chen CH, Thompson PM, Dale AM, Andreassen OA. Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms. Schizophrenia Bulletin. PMID 29136250 DOI: 10.1093/Schbul/Sbx148  0.723
2017 Lo MT, Wang Y, Kauppi K, Sanyal N, Fan CC, Smeland OB, Schork A, Holland D, Hinds DA, Tung JY, Andreassen OA, Dale AM, Chen CH. Modeling Prior Information of Common Genetic Variants Improves Gene Discovery for Neuroticism. Human Molecular Genetics. PMID 28973307 DOI: 10.1093/hmg/ddx340  0.489
2017 Smeland OB, Frei O, Kauppi K, Hill WD, Li W, Wang Y, Krull F, Bettella F, Eriksen JA, Witoelar A, Davies G, Fan CC, Thompson WK, Lam M, Lencz T, et al. Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function. Jama Psychiatry. PMID 28746715 DOI: 10.1001/Jamapsychiatry.2017.1986  0.683
2017 Smeland OB, Wang Y, Lo MT, Li W, Frei O, Witoelar A, Tesli M, Hinds DA, Tung JY, Djurovic S, Chen CH, Dale AM, Andreassen OA. Identification of genetic loci shared between schizophrenia and the Big Five personality traits. Scientific Reports. 7: 2222. PMID 28533504 DOI: 10.1038/S41598-017-02346-3  0.758
2017 Lo MT, Hinds DA, Tung JY, Franz C, Fan CC, Wang Y, Smeland OB, Schork A, Holland D, Kauppi K, Sanyal N, Escott-Price V, Smith DJ, O'Donovan M, Stefansson H, et al. Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Nature Genetics. 49: 152-156. PMID 27918536 DOI: 10.1038/Ng.3736  0.654
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