| Year |
Citation |
Score |
| 2012 |
Mathieu S, Gradl SN, Ren L, Wen Z, Aliagas I, Gunzner-Toste J, Lee W, Pulk R, Zhao G, Alicke B, Boggs JW, Buckmelter AJ, Choo EF, Dinkel V, Gloor SL, et al. Potent and selective aminopyrimidine-based B-Raf inhibitors with favorable physicochemical and pharmacokinetic properties. Journal of Medicinal Chemistry. 55: 2869-81. PMID 22335519 DOI: 10.1021/Jm300016V |
0.301 |
|
| 2007 |
Trauner D, Miller A, Hughes C, Kennedy-Smith J, Gradl S. Synthesis of (-)-Heptemerone B Synfacts. 2007: 0455-0455. DOI: 10.1055/S-2007-968393 |
0.569 |
|
| 2007 |
Gradl SN, Trauner D. The Meerwein-Eschenmoser-Claisen Rearrangement The Claisen Rearrangement: Methods and Applications. 367-396. DOI: 10.1002/9783527610549.ch7 |
0.448 |
|
| 2006 |
Miller AK, Hughes CC, Kennedy-Smith JJ, Gradl SN, Trauner D. Total synthesis of (-)-heptemerone B and (-)-guanacastepene E. Journal of the American Chemical Society. 128: 17057-62. PMID 17177458 DOI: 10.1021/Ja0660507 |
0.591 |
|
| 2003 |
Liang G, Gradl SN, Trauner D. Efficient Nazarov cyclizations of 2-alkoxy-1,4-pentadien-3-ones. Organic Letters. 5: 4931-4. PMID 14682732 DOI: 10.1021/Ol036019Z |
0.594 |
|
| 2003 |
Gradl SN, Felix JP, Isacoff EY, Garcia ML, Trauner D. Protein surface recognition by rational design: nanomolar ligands for potassium channels. Journal of the American Chemical Society. 125: 12668-9. PMID 14558789 DOI: 10.1021/Ja036155Z |
0.358 |
|
| 2002 |
Gradl SN, Kennedy-Smith JJ, Kim J, Trauner D. A Practical Variant of the Claisen-Eschenmoser Rearrangement: Synthesis of Unsaturated Morpholine Amides Synlett. 2002: 0411-0414. DOI: 10.1055/S-2002-20453 |
0.565 |
|
| 2002 |
Gradl SN, Kennedy-Smith JJ, Kim J, Trauner D. A practical variant of the Claisen-Eschenmoser rearrangement: Synthesis of unsaturated morpholine amides Synlett. 411-414. |
0.516 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2011 |
Wenglowsky S, Ahrendt KA, Buckmelter AJ, Feng B, Gloor SL, Gradl S, Grina J, Hansen JD, Laird ER, Lunghofer P, Mathieu S, Moreno D, Newhouse B, Ren L, Risom T, et al. Pyrazolopyridine inhibitors of B-RafV600E. Part 2: structure-activity relationships. Bioorganic & Medicinal Chemistry Letters. 21: 5533-7. PMID 21802293 DOI: 10.1016/J.Bmcl.2011.06.097 |
0.245 |
|
| 2012 |
Ren L, Laird ER, Buckmelter AJ, Dinkel V, Gloor SL, Grina J, Newhouse B, Rasor K, Hastings G, Gradl SN, Rudolph J. Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-Raf V600E kinase with favorable physicochemical and pharmacokinetic properties Bioorganic and Medicinal Chemistry Letters. 22: 1165-1168. PMID 22196124 DOI: 10.1016/J.Bmcl.2011.11.092 |
0.229 |
|
| 2019 |
Lewis TA, de Waal L, Wu X, Youngsaye W, Wengner A, Kopitz C, Lange M, Gradl S, Ellermann M, Lienau P, Schreiber SL, Greulich H, Meyerson M. Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing. Acs Medicinal Chemistry Letters. 10: 1537-1542. PMID 31749907 DOI: 10.1021/Acsmedchemlett.9B00360 |
0.17 |
|
| 2022 |
Shi DD, Savani MR, Levitt MM, Wang AC, Endress JE, Bird CE, Buehler J, Stopka SA, Regan MS, Lin YF, Puliyappadamba VT, Gao W, Khanal J, Evans L, Lee JH, ... ... Gradl S, et al. De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma. Cancer Cell. PMID 35985343 DOI: 10.1016/j.ccell.2022.07.011 |
0.142 |
|
| 2020 |
Eaton JK, Furst L, Ruberto RA, Moosmayer D, Hilpmann A, Ryan MJ, Zimmermann K, Cai LL, Niehues M, Badock V, Kramm A, Chen S, Hillig RC, Clemons PA, Gradl S, et al. Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles. Nature Chemical Biology. PMID 32231343 DOI: 10.1038/S41589-020-0501-5 |
0.105 |
|
| 2012 |
Zak M, Mendonca R, Balazs M, Barrett K, Bergeron P, Blair WS, Chang C, Deshmukh G, Devoss J, Dragovich PS, Eigenbrot C, Ghilardi N, Gibbons P, Gradl S, Hamman C, et al. Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2. Journal of Medicinal Chemistry. 55: 6176-93. PMID 22698084 DOI: 10.1021/Jm300628C |
0.094 |
|
| 2021 |
Moosmayer D, Hilpmann A, Hoffmann J, Schnirch L, Zimmermann K, Badock V, Furst L, Eaton JK, Viswanathan VS, Schreiber SL, Gradl S, Hillig RC. Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162. Acta Crystallographica. Section D, Structural Biology. 77: 237-248. PMID 33559612 DOI: 10.1107/S2059798320016125 |
0.09 |
|
| 2013 |
Zak M, Hurley CA, Ward SI, Bergeron P, Barrett K, Balazs M, Blair WS, Bull R, Chakravarty P, Chang C, Crackett P, Deshmukh G, DeVoss J, Dragovich PS, Eigenbrot C, ... ... Gradl S, et al. Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2. Journal of Medicinal Chemistry. 56: 4764-85. PMID 23659214 DOI: 10.1021/Jm4004895 |
0.078 |
|
| 2019 |
Christian S, Merz C, Evans L, Gradl S, Seidel H, Friberg A, Eheim A, Lejeune P, Brzezinka K, Zimmermann K, Ferrara S, Meyer H, Lesche R, Stoeckigt D, Bauser M, et al. The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. Leukemia. PMID 30940908 DOI: 10.1038/S41375-019-0461-5 |
0.075 |
|
| 2020 |
Mortier J, Friberg A, Badock V, Moosmayer D, Schroeder J, Steigemann P, Siegel F, Gradl S, Bauser M, Hillig RC, Briem H, Eis K, Bader B, Nguyen D, Christ CD. Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRAS. Chemmedchem. PMID 32237114 DOI: 10.1002/cmdc.201900727 |
0.066 |
|
| 2021 |
Gradl S, Steuber H, Weiske J, Szewczyk MM, Schmees N, Siegel S, Stoeckigt D, Christ CD, Li F, Organ S, Abbey M, Kennedy S, Chau I, Trush V, Barsyte-Lovejoy D, et al. Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening. Slas Discovery : Advancing Life Sciences R & D. 24725552211019409. PMID 34154424 DOI: 10.1177/24725552211019409 |
0.051 |
|
| 2023 |
Göricke F, Vu V, Smith L, Scheib U, Böhm R, Akkilic N, Wohlfahrt G, Weiske J, Bömer U, Brzezinka K, Lindner N, Lienau P, Gradl S, Beck H, Brown PJ, et al. Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21. Journal of Medicinal Chemistry. PMID 36802665 DOI: 10.1021/acs.jmedchem.2c01933 |
0.049 |
|
| 2020 |
Lefranc J, Schulze VK, Hillig RC, Briem H, Prinz F, Mengel A, Heinrich T, Balint J, Rengachari S, Irlbacher H, Stöckigt D, Bömer U, Bader B, Gradl SN, Nising CF, et al. Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor. Journal of Medicinal Chemistry. 63: 601-612. PMID 31859507 DOI: 10.1021/acs.jmedchem.9b01460 |
0.035 |
|
| 2021 |
Wirth M, Kohl S, Gradl S, Farlock R, Roth D, Eskofier BM. Assessing Visual Exploratory Activity of Athletes in Virtual Reality Using Head Motion Characteristics. Sensors (Basel, Switzerland). 21. PMID 34071960 DOI: 10.3390/s21113728 |
0.033 |
|
| 2019 |
Feigl T, Roth D, Gradl S, Wirth M, Latoschik ME, Eskofier BM, Philippsen M, Mutschler C. Sick Moves! Motion Parameters as Indicators of Simulator Sickness. Ieee Transactions On Visualization and Computer Graphics. 25: 3146-3157. PMID 31425036 DOI: 10.1109/Tvcg.2019.2932224 |
0.025 |
|
| 2017 |
Altini M, Mullan P, Rooijakkers M, Gradl S, Penders J, Geusens N, Grieten L, Eskofier B. Detection of fetal kicks using body-worn accelerometers during pregnancy: Trade-offs between sensors number and positioning. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2016: 5319-5322. PMID 28269461 DOI: 10.1109/EMBC.2016.7591928 |
0.019 |
|
| 2013 |
Gradl S, Leutheuser H, Kugler P, Biermann T, Kreil S, Kornhuber J, Bergner M, Eskofier B. Somnography using unobtrusive motion sensors and Android-based mobile phones. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2013: 1182-5. PMID 24109904 DOI: 10.1109/EMBC.2013.6609717 |
0.017 |
|
| 2018 |
Zrenner M, Gradl S, Jensen U, Ullrich M, Eskofier BM. Comparison of Different Algorithms for Calculating Velocity and Stride Length in Running Using Inertial Measurement Units. Sensors (Basel, Switzerland). 18. PMID 30513595 DOI: 10.3390/s18124194 |
0.016 |
|
| 2015 |
Gradl S, Leutheuser H, Elgendi M, Lang N, Eskofier BM. Temporal correction of detected R-peaks in ECG signals: A crucial step to improve QRS detection algorithms. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2015: 522-5. PMID 26736314 DOI: 10.1109/EMBC.2015.7318414 |
0.011 |
|
| 2022 |
Flaucher M, Nissen M, Jaeger KM, Titzmann A, Pontones C, Huebner H, Fasching PA, Beckmann MW, Gradl S, Eskofier BM. Smartphone-Based Colorimetric Analysis of Urine Test Strips for At-Home Prenatal Care. Ieee Journal of Translational Engineering in Health and Medicine. 10: 2800109. PMID 35865751 DOI: 10.1109/JTEHM.2022.3179147 |
0.01 |
|
| 2022 |
Nissen M, Slim S, Jäger K, Flaucher M, Huebner H, Danzberger N, Fasching PA, Beckmann MW, Gradl S, Eskofier BM. Heart Rate Measurement Accuracy of Fitbit Charge 4 and Samsung Galaxy Watch Active2: Device Evaluation Study. Jmir Formative Research. 6: e33635. PMID 35230250 DOI: 10.2196/33635 |
0.01 |
|
| 2021 |
Bachmann J, Zabicki A, Gradl S, Kurz J, Munzert J, Troje NF, Krueger B. Does co-presence affect the way we perceive and respond to emotional interactions? Experimental Brain Research. PMID 33427949 DOI: 10.1007/s00221-020-06020-5 |
0.01 |
|
| 2014 |
Leutheuser H, Gradl S, Kugler P, Anneken L, Arnold M, Achenbach S, Eskofier BM. Comparison of real-time classification systems for arrhythmia detection on Android-based mobile devices. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2014: 2690-3. PMID 25570545 DOI: 10.1109/EMBC.2014.6944177 |
0.01 |
|
| 2013 |
Musshoff F, Wolters T, Lott S, Ippisch J, Gradl S, Madea B. Optimization and validation of CEDIA drugs of abuse immunoassay tests in serum and urine on an Olympus AU 400. Drug Testing and Analysis. 5: 366-71. PMID 23386567 DOI: 10.1002/dta.1454 |
0.01 |
|
| 2013 |
Gradl S, Kugler P, Lohmuller C, Eskofier B. Real-time ECG monitoring and arrhythmia detection using Android-based mobile devices. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2012: 2452-5. PMID 23366421 DOI: 10.1109/EMBC.2012.6346460 |
0.01 |
|
| Hide low-probability matches. |