Manel Esteller - Publications

Affiliations: 
2015- Cancer Epigenetics and Biology Program (PEBC Bellvitge Biomedical Research Institute 

257 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bueno-Costa A, Piñeyro D, Soler M, Javierre BM, Raurell-Vila H, Subirana-Granés M, Pasquali L, Martinez-Climent JA, Esteller M. B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation. Leukemia. PMID 31719676 DOI: 10.1038/s41375-019-0643-1  0.36
2019 Oliveira-Mateos C, Sánchez-Castillo A, Soler M, Obiols-Guardia A, Piñeyro D, Boque-Sastre R, Calleja-Cervantes ME, Castro de Moura M, Martínez-Cardús A, Rubio T, Pelletier J, Martínez-Iniesta M, Herrero-Martín D, Tirado OM, Gentilella A, ... ... Esteller M, et al. The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition. Nature Communications. 10: 3979. PMID 31484926 DOI: 10.1038/s41467-019-11910-6  1
2019 Janin M, Ortiz-Barahona V, de Moura MC, Martínez-Cardús A, Llinàs-Arias P, Soler M, Nachmani D, Pelletier J, Schumann U, Calleja-Cervantes ME, Moran S, Guil S, Bueno-Costa A, Piñeyro D, Perez-Salvia M, ... ... Esteller M, et al. Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program. Acta Neuropathologica. PMID 31428936 DOI: 10.1007/s00401-019-02062-4  1
2019 Piqué L, Martinez de Paz A, Piñeyro D, Martínez-Cardús A, Castro de Moura M, Llinàs-Arias P, Setien F, Gomez-Miragaya J, Gonzalez-Suarez E, Sigurdsson S, Jonasson JG, Villanueva A, Vidal A, Davalos V, Esteller M. Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer. Oncogene. PMID 31409895 DOI: 10.1038/s41388-019-0936-x  0.36
2019 Gómez-Miragaya J, Morán S, Calleja-Cervantes ME, Collado-Solé A, Paré L, Gómez A, Serra V, Dobrolecki LE, Lewis MT, Diaz-Lagares A, Eroles P, Prat A, Esteller M, González-Suárez E. The altered transcriptome and DNA methylation profiles of docetaxel resistance in breast cancer PDX models. Molecular Cancer Research : McR. PMID 31320385 DOI: 10.1158/1541-7786.MCR-19-0040  0.32
2019 Llinàs-Arias P, Rosselló-Tortella M, Lopez-Serra P, Pérez-Salvia M, Setién F, Marin S, Muñoz JP, Junza A, Capellades J, Calleja-Cervantes ME, Ferreira HJ, Castro de Moura M, Srbic M, Martínez-Cardús A, de la Torre C, ... ... Esteller M, et al. Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming. Jci Insight. 5. PMID 30843871 DOI: 10.1172/jci.insight.125888  0.36
2019 Belhadj S, Moutinho C, Mur P, Setien F, Llinàs-Arias P, Perez-Salvia M, Pons T, Pineda M, Brunet J, Navarro M, Capellà G, Esteller M, Valle L. Germline variation in O-Methylguanine-DNA Methyltransferase (MGMT) as cause of hereditary colorectal cancer. Cancer Letters. PMID 30677446 DOI: 10.1016/j.canlet.2019.01.019  0.36
2019 Requena J, Alvarez-Palomo AB, Codina-Pascual M, Delgado-Morales R, Moran S, Esteller M, Sal M, Juan-Otero M, Boronat Barado A, Consiglio A, Addeleccia Bogle O, Wolvertang E, Ovchinnikov D, Alvarez I, Jaraquemada D, et al. Global proteomic and methylome analysis in human induced pluripotent stem cells reveals overexpression of a human TLR3 affecting proper innate immune response signaling. Stem Cells (Dayton, Ohio). PMID 30664289 DOI: 10.1002/stem.2966  0.52
2018 Ferreira HJ, Davalos V, de Moura MC, Soler M, Perez-Salvia M, Bueno-Costa A, Setien F, Moran S, Villanueva A, Esteller M. Circular RNA CpG island hypermethylation-associated silencing in human cancer. Oncotarget. 9: 29208-29219. PMID 30018746 DOI: 10.18632/oncotarget.25673  0.36
2018 Perez-Salvia M, Aldaba E, Vara Y, Fabre M, Ferrer C, Masdeu C, Zubia A, San Sebastian E, Otaegui D, Llinàs-Arias P, Rosselló-Tortella M, Berdasco M, Moutinho C, Setien F, Villanueva A, ... ... Esteller M, et al. In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma. Haematologica. PMID 29880608 DOI: 10.3324/haematol.2018.189241  0.36
2018 Jorge-Torres OC, Szczesna K, Roa L, Casal C, Gonzalez-Somermeyer L, Soler M, Velasco CD, Martínez-San Segundo P, Petazzi P, Sáez MA, Delgado-Morales R, Fourcade S, Pujol A, Huertas D, Llobet A, ... ... Esteller M, et al. Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice. Cell Reports. 23: 1665-1677. PMID 29742424 DOI: 10.1016/j.celrep.2018.04.010  1
2018 Sanchez-Mut JV, Heyn H, Silva BA, Dixsaut L, Garcia-Esparcia P, Vidal E, Sayols S, Glauser L, Monteagudo-Sánchez A, Perez-Tur J, Ferrer I, Monk D, Schneider B, Esteller M, Gräff J. PM20D1 is a quantitative trait locus associated with Alzheimer's disease. Nature Medicine. PMID 29736028 DOI: 10.1038/s41591-018-0013-y  0.36
2018 Piulats JM, Vidal A, García-Rodríguez FJ, Muñoz C, Nadal M, Moutinho C, Martínez-Iniesta M, Mora J, Figueras A, Guinó E, Padullés L, Aytés À, Mollevi DG, Puertas S, Martínez-Fernández C, ... ... Esteller M, et al. Orthoxenografts of testicular germ cell tumors demonstrate genomic changes associated with cisplatin resistance and identify PDMP as a re-sensitizing agent. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29618620 DOI: 10.1158/1078-0432.CCR-17-1898  0.36
2017 Bosch-Presegué L, Raurell-Vila H, Thackray JK, González J, Casal C, Kane-Goldsmith N, Vizoso M, Brown JP, Gómez A, Ausió J, Zimmermann T, Esteller M, Schotta G, Singh PB, Serrano L, et al. Mammalian HP1 Isoforms Have Specific Roles in Heterochromatin Structure and Organization. Cell Reports. 21: 2048-2057. PMID 29166597 DOI: 10.1016/j.celrep.2017.10.092  0.32
2017 Berdasco M, Gómez A, Rubio MJ, Català-Mora J, Zanón-Moreno V, Lopez M, Hernández C, Yoshida S, Nakama T, Ishikawa K, Ishibashi T, Boubekeur AM, Louhibi L, Pujana MA, Sayols S, ... ... Esteller M, et al. DNA Methylomes Reveal Biological Networks Involved in Human Eye Development, Functions and Associated Disorders. Scientific Reports. 7: 11762. PMID 28924151 DOI: 10.1038/s41598-017-12084-1  0.36
2017 Moutinho C, Esteller M. MicroRNAs and Epigenetics. Advances in Cancer Research. 135: 189-220. PMID 28882223 DOI: 10.1016/bs.acr.2017.06.003  0.36
2017 Pérez-Salvia M, Simó-Riudalbas L, Llinàs-Arias P, Roa L, Setien F, Soler M, de Moura MC, Bradner JE, Gonzalez-Suarez E, Moutinho C, Esteller M. Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer. Oncotarget. 8: 51621-51629. PMID 28881673 DOI: 10.18632/oncotarget.18255  0.36
2017 Delgado-Morales R, Agís-Balboa RC, Esteller M, Berdasco M. Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders. Clinical Epigenetics. 9: 67. PMID 28670349 DOI: 10.1186/s13148-017-0365-z  0.52
2017 Pérez-Salvia M, Simó-Riudalbas L, Llinàs-Arias P, Roa L, Setien F, Soler M, Castro de Moura M, Bradner JE, Gonzalez-Suarez E, Moutinho C, Esteller M. Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer. Oncotarget. PMID 28624801 DOI: 10.18632/oncotarget.18255  0.36
2017 Sia D, Jiao Y, Martinez-Quetglas I, Kuchuk O, Villacorta-Martin C, Castro de Moura M, Putra J, Camprecios G, Bassaganyas L, Akers N, Losic B, Waxman S, Thung SN, Mazzaferro V, Esteller M, et al. Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features. Gastroenterology. PMID 28624577 DOI: 10.1053/j.gastro.2017.06.007  0.36
2017 Vidal E, Sayols S, Moran S, Guillaumet-Adkins A, Schroeder MP, Royo R, Orozco M, Gut M, Gut I, Lopez-Bigas N, Heyn H, Esteller M. A DNA methylation map of human cancer at single base-pair resolution. Oncogene. PMID 28581523 DOI: 10.1038/onc.2017.176  0.36
2017 Riemens RJM, Soares ES, Esteller M, Delgado-Morales R. Stem Cell Technology for (Epi)genetic Brain Disorders. Advances in Experimental Medicine and Biology. 978: 443-475. PMID 28523560 DOI: 10.1007/978-3-319-53889-1_23  0.52
2017 Ferreira HJ, Heyn H, Vizoso M, Moutinho C, Vidal E, Gomez A, Martínez-Cardús A, Simó-Riudalbas L, Moran S, Jost E, Esteller M. DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia. Oncogene. PMID 28288143 DOI: 10.1038/onc.2017.57  0.36
2017 Sanchez-Mut JV, Heyn H, Vidal E, Delgado-Morales R, Moran S, Sayols S, Sandoval J, Ferrer I, Esteller M, Gräff J. Whole Genome Grey and White matter DNA Methylation Profiles in Dorsolateral Prefrontal cortex. Synapse (New York, N.Y.). PMID 28105729 DOI: 10.1002/syn.21959  0.52
2016 Mateo F, Arenas EJ, Aguilar H, Serra-Musach J, de Garibay GR, Boni J, Maicas M, Du S, Iorio F, Herranz-Ors C, Islam A, Prado X, Llorente A, Petit A, Vidal A, ... ... Esteller M, et al. Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition. Oncogene. PMID 27991928 DOI: 10.1038/onc.2016.427  0.36
2016 Diaz-Lagares A, Crujeiras AB, Lopez-Serra P, Soler M, Setien F, Goyal A, Sandoval J, Hashimoto Y, Martinez-Cardús A, Gomez A, Heyn H, Moutinho C, Espada J, Vidal A, Paúles M, ... ... Esteller M, et al. Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821766 DOI: 10.1073/pnas.1608585113  1
2016 Lopez-Serra P, Marcilla M, Villanueva A, Ramos-Fernandez A, Palau A, Leal L, Wahi JE, Setien-Baranda F, Szczesna K, Moutinho C, Martinez-Cardus A, Heyn H, Sandoval J, Puertas S, Vidal A, ... ... Esteller M, et al. Corrigendum: A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect. Nature Communications. 7: 13467. PMID 27804975 DOI: 10.1038/ncomms13467  0.36
2016 Martinez-Quetglas I, Pinyol R, Dauch D, Torrecilla S, Tovar V, Moeini A, Alsinet C, Portela A, Rodriguez-Carunchio L, Solé M, Lujambio A, Villanueva A, Thung S, Esteller M, Zender L, et al. IGF2 is Upregulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and is an Actionable Oncogene Product in Experimental Models. Gastroenterology. PMID 27614046 DOI: 10.1053/j.gastro.2016.09.001  0.36
2016 Moran S, Martínez-Cardús A, Sayols S, Musulén E, Balañá C, Estival-Gonzalez A, Moutinho C, Heyn H, Diaz-Lagares A, de Moura MC, Stella GM, Comoglio PM, Ruiz-Miró M, Matias-Guiu X, Pazo-Cid R, ... ... Esteller M, et al. Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis. The Lancet. Oncology. PMID 27575023 DOI: 10.1016/S1470-2045(16)30297-2  0.36
2016 Serra-Musach J, Mateo F, Capdevila-Busquets E, de Garibay GR, Zhang X, Guha R, Thomas CJ, Grueso J, Villanueva A, Jaeger S, Heyn H, Vizoso M, Pérez H, Cordero A, Gonzalez-Suarez E, ... Esteller M, et al. Cancer network activity associated with therapeutic response and synergism. Genome Medicine. 8: 88. PMID 27553366 DOI: 10.1186/s13073-016-0340-x  1
2016 Lucariello M, Vidal E, Vidal S, Saez M, Roa L, Huertas D, Pineda M, Dalfó E, Dopazo J, Jurado P, Armstrong J, Esteller M. Whole exome sequencing of Rett syndrome-like patients reveals the mutational diversity of the clinical phenotype. Human Genetics. PMID 27541642 DOI: 10.1007/s00439-016-1721-3  1
2016 Martínez-Cardús A, Moran S, Musulen E, Moutinho C, Manzano JL, Martinez-Balibrea E, Tierno M, Élez E, Landolfi S, Lorden P, Arribas C, Müller F, Bock C, Tabernero J, Esteller M. Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-free and Overall Survival Times for Patients With Loco-regional Cancer. Gastroenterology. PMID 27521480 DOI: 10.1053/j.gastro.2016.08.001  0.36
2016 Toll A, Salgado R, Espinet B, Díaz-Lagares A, Hernández-Ruiz E, Andrades E, Sandoval J, Esteller M, Pujol RM, Hernández-Muñoz I. MiR-204 silencing in intraepithelial to invasive cutaneous squamous cell carcinoma progression. Molecular Cancer. 15: 53. PMID 27457246 DOI: 10.1186/s12943-016-0537-z  1
2016 Iorio F, Knijnenburg TA, Vis DJ, Bignell GR, Menden MP, Schubert M, Aben N, Gonçalves E, Barthorpe S, Lightfoot H, Cokelaer T, Greninger P, van Dyk E, Chang H, de Silva H, ... ... Esteller M, et al. A Landscape of Pharmacogenomic Interactions in Cancer. Cell. PMID 27397505 DOI: 10.1016/j.cell.2016.06.017  1
2016 Ter Brugge P, Kristel P, van der Burg E, Boon U, de Maaker M, Lips E, Mulder L, de Ruiter J, Moutinho C, Gevensleben H, Marangoni E, Majewski I, Jóźwiak K, Kloosterman W, van Roosmalen M, ... ... Esteller M, et al. Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer. Journal of the National Cancer Institute. 108. PMID 27381626 DOI: 10.1093/jnci/djw148  0.36
2016 Anadón C, Guil S, Simó-Riudalbas L, Moutinho C, Setien F, Martínez-Cardús A, Moran S, Villanueva A, Calaf M, Vidal A, Lazo PA, Zondervan I, Savola S, Kohno T, Yokota J, ... ... Esteller M, et al. Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis. Oncogene. PMID 27345394 DOI: 10.1038/onc.2016.27  1
2016 Silva-Martínez GA, Rodríguez-Ríos D, Alvarado-Caudillo Y, Vaquero A, Esteller M, Carmona FJ, Moran S, Nielsen FC, Wickström-Lindholmx M, Wrobel K, Wrobel K, Barbosa-Sabanero G, Zaina S, Lund G. Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 0. PMID 27088456 DOI: 10.1080/15592294.2016.1161873  1
2016 Villalba M, Diaz-Lagares A, Redrado M, de Aberasturi AL, Segura V, Bodegas ME, Pajares MJ, Pio R, Freire J, Gomez-Roman J, Montuenga LM, Esteller M, Sandoval J, Calvo A. Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients. Oncotarget. PMID 26989022 DOI: 10.18632/oncotarget.8045  1
2016 Nuñez O, Román A, Johnson SR, Inoue Y, Hirose M, Casanova Á, de Garibay GR, Herranz C, Bueno-Moreno G, Boni J, Mateo F, Petit A, Climent F, Soler T, Vidal A, ... ... Esteller M, et al. Study of breast cancer incidence in patients of lymphangioleiomyomatosis. Breast Cancer Research and Treatment. PMID 26951504 DOI: 10.1007/s10549-016-3737-8  1
2016 Amatu A, Barault L, Moutinho C, Cassingena A, Bencardino K, Ghezzi S, Palmeri L, Bonazzina E, Tosi F, Ricotta R, Cipani T, Crivori P, Gatto R, Chirico G, Marrapese G, ... ... Esteller M, et al. Tumor MGMT promoter hypermethylation changes over time limit temozolomide efficacy in a phase II trial for metastatic colorectal cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 26916096 DOI: 10.1093/annonc/mdw071  0.36
2016 Diaz-Lagares A, Mendez-Gonzalez J, Hervas D, Saigi M, Pajares MJ, Garcia D, Crujeiras AB, Pio R, Montuenga LM, Zulueta J, Nadal E, Rosell A, Esteller M, Sandoval Del Amor J. A novel epigenetic signature for early diagnosis in lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26842235 DOI: 10.1158/1078-0432.CCR-15-2346  1
2016 Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, Calin GA, Rossi S, Fernandez AF, Carneiro F, Oliveira C, Ferreira B, Liu CG, Villanueva A, Capella G, Schwartz S, ... ... Esteller M, et al. Retraction: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nature Genetics. 48: 221. PMID 26813765 DOI: 10.1038/ng0216-221  0.36
2016 Heyn H, Vidal E, Ferreira HJ, Vizoso M, Sayols S, Gomez A, Moran S, Boque-Sastre R, Guil S, Martinez-Cardus A, Lin CY, Royo R, Sanchez-Mut JV, Martinez R, Gut M, ... ... Esteller M, et al. Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer. Genome Biology. 17: 11. PMID 26813288 DOI: 10.1186/s13059-016-0879-2  1
2016 Sanchez-Mut JV, Heyn H, Vidal E, Moran S, Sayols S, Delgado-Morales R, Schultz MD, Ansoleaga B, Garcia-Esparcia P, Pons-Espinal M, de Lagran MM, Dopazo J, Rabano A, Avila J, Dierssen M, ... ... Esteller M, et al. Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns. Translational Psychiatry. 6: e718. PMID 26784972 DOI: 10.1038/tp.2015.214  0.52
2016 Royo F, Zuñiga-Garcia P, Torrano V, Loizaga A, Sanchez-Mosquera P, Ugalde-Olano A, González E, Cortazar AR, Palomo L, Fernández-Ruiz S, Lacasa-Viscasillas I, Berdasco M, Sutherland JD, Barrio R, Zabala-Letona A, ... ... Esteller M, et al. Transcriptomic profiling of urine extracellular vesicles reveals alterations of CDH3 in prostate cancer. Oncotarget. PMID 26771841 DOI: 10.18632/oncotarget.6899  1
2016 Vento-Tormo R, Company C, Rodríguez-Ubreva J, de la Rica L, Urquiza JM, Javierre BM, Sabarinathan R, Luque A, Esteller M, Aran JM, Álvarez-Errico D, Ballestar E. IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation. Genome Biology. 17: 4. PMID 26758199 DOI: 10.1186/s13059-015-0863-2  1
2016 Bolós V, Peinado H, Pérez-Moreno MA, Fraga MF, Esteller M, Cano A. Correction to The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors [J. Cell Sci. 116, (2003) 499-511] Journal of Cell Science. 129: 1283. DOI: 10.1242/jcs.188243  1
2015 da Silva-Diz V, Simón-Extremera P, Bernat-Peguera A, de Sostoa J, Urpí M, Penin RM, Pérez Sidelnikova D, Bermejo O, Viñals JM, Rodolosse A, Gonzalez-Suarez E, Gómez Moruno A, Pujana MA, Esteller M, Villanueva A, et al. Cancer stem cell regulation changes at late stages of skin carcinoma progression to enhance tumor growth and metastasis. Cancer Research. PMID 26719534 DOI: 10.1158/0008-5472.CAN-15-1631  1
2015 Moran S, Arribas C, Esteller M. Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences. Epigenomics. PMID 26673039 DOI: 10.2217/epi.15.114  1
2015 Anadón C, Guil S, Simó-Riudalbas L, Moutinho C, Setien F, Martínez-Cardús A, Moran S, Villanueva A, Calaf M, Vidal A, Lazo PA, Zondervan I, Savola S, Kohno T, Yokota J, ... ... Esteller M, et al. Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis. Oncogene. PMID 26640150 DOI: 10.1038/onc.2015.469  1
2015 Nogales V, Reinhold WC, Varma S, Martinez-Cardus A, Moutinho C, Moran S, Heyn H, Sebio A, Barnadas A, Pommier Y, Esteller M. Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs. Oncotarget. PMID 26625211 DOI: 10.18632/oncotarget.6413  1
2015 Adams BD, Anastasiadou E, Esteller M, He L, Slack FJ. The Inescapable Influence of Noncoding RNAs in Cancer. Cancer Research. PMID 26567137 DOI: 10.1158/0008-5472.CAN-15-1989  1
2015 Sanchez-Delgado M, Martin-Trujillo A, Tayama C, Vidal E, Esteller M, Iglesias-Platas I, Deo N, Barney O, Maclean K, Hata K, Nakabayashi K, Fisher R, Monk D. Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting. Plos Genetics. 11: e1005644. PMID 26544189 DOI: 10.1371/journal.pgen.1005644  1
2015 Vizoso M, Esteller M. Targeting melanoma: unusual epigenetics reveals the dynamic rewiring of metastatic cells. Epigenomics. PMID 26541242 DOI: 10.2217/epi.15.67  1
2015 Vizoso M, Puig M, Carmona FJ, Maqueda M, Velásquez A, Gomez A, Labernadie A, Lugo R, Gabasa M, Rigat-Brugarolas LG, Trepat X, Ramírez J, Reguart N, Moran S, Vidal E, ... ... Esteller M, et al. Aberrant DNA methylation in Non Small Cell Lung Cancer associated fibroblasts. Carcinogenesis. PMID 26449251 DOI: 10.1093/carcin/bgv146  1
2015 Ferreira HJ, Heyn H, Vizoso M, Moutinho C, Vidal E, Gomez A, Martínez-Cardús A, Simó-Riudalbas L, Moran S, Jost E, Esteller M. DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia. Oncogene. PMID 26434589 DOI: 10.1038/onc.2015.359  0.36
2015 Calvete O, Martinez P, Garcia-Pavia P, Benitez-Buelga C, Paumard-Hernández B, Fernandez V, Dominguez F, Salas C, Romero-Laorden N, Garcia-Donas J, Carrillo J, Perona R, Triviño JC, Andrés R, Cano JM, ... ... Esteller M, et al. A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families. Nature Communications. 6: 8383. PMID 26403419 DOI: 10.1038/ncomms9383  1
2015 Gallardo F, Sandoval J, Díaz-Lagares A, Garcia R, D'Altri T, González J, Alegre V, Servitje O, Crujeiras AB, Stefánsson ÓA, Espinet B, Hernández MI, Bellosillo B, Esteller M, Pujol RM, et al. Notch1 Pathway Activation Results from the Epigenetic Abrogation of Notch-Related MicroRNAs in Mycosis Fungoides. The Journal of Investigative Dermatology. PMID 26302069 DOI: 10.1038/jid.2015.328  1
2015 Vizoso M, Esteller M. DNA methylation plasticity contributes to the natural history of metastasis. Cell Cycle (Georgetown, Tex.). 14: 2863-4. PMID 26223807 DOI: 10.1080/15384101.2015.1076300  1
2015 Simó-Riudalbas L, Pérez-Salvia M, Setien F, Villanueva A, Moutinho C, Martínez-Cardús A, Moran S, Berdasco M, Gomez A, Vidal E, Soler M, Heyn H, Vaquero A, de la Torre C, Barceló-Batllori S, ... ... Esteller M, et al. KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer. Cancer Research. 75: 3936-45. PMID 26208904 DOI: 10.1158/0008-5472.CAN-14-3702  1
2015 Martinez-Balibrea E, Martínez-Cardús A, Ginés A, Ruiz de Porras V, Moutinho C, Layos L, Manzano JL, Bugés C, Bystrup S, Esteller M, Abad A. Tumor-Related Molecular Mechanisms of Oxaliplatin Resistance. Molecular Cancer Therapeutics. 14: 1767-76. PMID 26184483 DOI: 10.1158/1535-7163.MCT-14-0636  1
2015 Sáez MA, Fernández-Rodríguez J, Moutinho C, Sanchez-Mut JV, Gomez A, Vidal E, Petazzi P, Szczesna K, Lopez-Serra P, Lucariello M, Lorden P, Delgado-Morales R, de la Caridad OJ, Huertas D, Gelpí JL, ... ... Esteller M, et al. Mutations in JMJD1C are involved in Rett syndrome and intellectual disability. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 26181491 DOI: 10.1038/gim.2015.100  1
2015 Hernando-Herraez I, Heyn H, Fernandez-Callejo M, Vidal E, Fernandez-Bellon H, Prado-Martinez J, Sharp AJ, Esteller M, Marques-Bonet T. The interplay between DNA methylation and sequence divergence in recent human evolution. Nucleic Acids Research. 43: 8204-14. PMID 26170231 DOI: 10.1093/nar/gkv693  1
2015 Ruiz de Garibay G, Herranz C, Llorente A, Boni J, Serra-Musach J, Mateo F, Aguilar H, Gómez-Baldó L, Petit A, Vidal A, Climent F, Hernández-Losa J, Cordero Á, González-Suárez E, Sánchez-Mut JV, ... Esteller M, et al. Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness. Plos One. 10: e0132546. PMID 26167915 DOI: 10.1371/journal.pone.0132546  1
2015 Simo-Riudalbas L, Diaz-Lagares A, Gatto S, Gagliardi M, Crujeiras AB, Matarazzo MR, Esteller M, Sandoval J. Genome-Wide DNA Methylation Analysis Identifies Novel Hypomethylated Non-Pericentromeric Genes with Potential Clinical Implications in ICF Syndrome. Plos One. 10: e0132517. PMID 26161907 DOI: 10.1371/journal.pone.0132517  1
2015 Barault L, Amatu A, Bleeker FE, Moutinho C, Falcomatà C, Fiano V, Cassingena A, Siravegna G, Milione M, Cassoni P, De Braud F, Rudà R, Soffietti R, Venesio T, Bardelli A, ... ... Esteller M, et al. Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 26113646 DOI: 10.1093/annonc/mdv272  1
2015 Zaina S, Gonçalves I, Carmona FJ, Gomez A, Heyn H, Mollet IG, Moran S, Varol N, Esteller M. DNA Methylation Dynamics in Human Carotid Plaques After Cerebrovascular Events. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26088578 DOI: 10.1161/ATVBAHA.115.305630  1
2015 Vaclová T, Gómez-López G, Setién F, Bueno JM, Macías JA, Barroso A, Urioste M, Esteller M, Benítez J, Osorio A. DNA repair capacity is impaired in healthy BRCA1 heterozygous mutation carriers. Breast Cancer Research and Treatment. PMID 26071757 DOI: 10.1007/s10549-015-3459-3  1
2015 Vizoso M, Ferreira HJ, Lopez-Serra P, Carmona FJ, Martínez-Cardús A, Girotti MR, Villanueva A, Guil S, Moutinho C, Liz J, Portela A, Heyn H, Moran S, Vidal A, Martinez-Iniesta M, ... ... Esteller M, et al. Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR. Nature Medicine. PMID 26030178 DOI: 10.1038/nm.3863  1
2015 Cappetta M, Berdasco M, Hochmann J, Bonilla C, Sans M, Hidalgo PC, Artagaveytia N, Kittles R, Martínez M, Esteller M, Bertoni B. Effect of genetic ancestry on leukocyte global DNA methylation in cancer patients. Bmc Cancer. 15: 434. PMID 26012346 DOI: 10.1186/s12885-015-1461-0  1
2015 Perez-Salvia M, Simó-Riudalbas L, Ausió J, Esteller M. Barcelona conference on epigenetics and cancer: 50 years of histone acetylation. Epigenetics : Official Journal of the Dna Methylation Society. 10: 446-51. PMID 25942103 DOI: 10.1080/15592294.2015.1039222  1
2015 Heyn H, Esteller M. An Adenine Code for DNA: A Second Life for N6-Methyladenine. Cell. 161: 710-713. PMID 25936836 DOI: 10.1016/j.cell.2015.04.021  1
2015 Boque-Sastre R, Soler M, Oliveira-Mateos C, Portela A, Moutinho C, Sayols S, Villanueva A, Esteller M, Guil S. Head-to-head antisense transcription and R-loop formation promotes transcriptional activation. Proceedings of the National Academy of Sciences of the United States of America. 112: 5785-90. PMID 25902512 DOI: 10.1073/pnas.1421197112  1
2015 Gurnot C, Martin-Subero I, Mah SM, Weikum W, Goodman SJ, Brain U, Werker JF, Kobor MS, Esteller M, Oberlander TF, Hensch TK. Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates. Epigenetics : Official Journal of the Dna Methylation Society. 10: 361-72. PMID 25891251 DOI: 10.1080/15592294.2015.1026031  1
2015 Valencia-Morales Mdel P, Zaina S, Heyn H, Carmona FJ, Varol N, Sayols S, Condom E, Ramírez-Ruz J, Gomez A, Moran S, Lund G, Rodríguez-Ríos D, López-González G, Ramírez-Nava M, de la Rocha C, ... ... Esteller M, et al. The DNA methylation drift of the atherosclerotic aorta increases with lesion progression. Bmc Medical Genomics. 8: 7. PMID 25881171 DOI: 10.1186/s12920-015-0085-1  1
2015 Martínez de Paz A, Vicente Sanchez-Mut J, Samitier-Martí M, Petazzi P, Sáez M, Szczesna K, Huertas D, Esteller M, Ausió J. Circadian cycle-dependent MeCP2 and brain chromatin changes. Plos One. 10: e0123693. PMID 25875630 DOI: 10.1371/journal.pone.0123693  1
2015 Agrelo R, Sutz MA, Setien F, Aldunate F, Esteller M, Da Costa V, Achenbach R. A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapies. Epigenetics : Official Journal of the Dna Methylation Society. 10: 329-41. PMID 25830902 DOI: 10.1080/15592294.2015.1027853  1
2015 Guil S, Esteller M. RNA-RNA interactions in gene regulation: the coding and noncoding players. Trends in Biochemical Sciences. 40: 248-56. PMID 25818326 DOI: 10.1016/j.tibs.2015.03.001  1
2015 Léveillé N, Melo CA, Rooijers K, Díaz-Lagares A, Melo SA, Korkmaz G, Lopes R, Akbari Moqadam F, Maia AR, Wijchers PJ, Geeven G, den Boer ML, Kalluri R, de Laat W, Esteller M, et al. Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA. Nature Communications. 6: 6520. PMID 25813522 DOI: 10.1038/ncomms7520  1
2015 Cascón A, Comino-Méndez I, Currás-Freixes M, de Cubas AA, Contreras L, Richter S, Peitzsch M, Mancikova V, Inglada-Pérez L, Pérez-Barrios A, Calatayud M, Azriel S, Villar-Vicente R, Aller J, Setién F, ... ... Esteller M, et al. Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene. Journal of the National Cancer Institute. 107. PMID 25766404 DOI: 10.1093/jnci/djv053  1
2015 Barneda-Zahonero B, Collazo O, Azagra A, Fernández-Duran I, Serra-Musach J, Islam AB, Vega-García N, Malatesta R, Camós M, Gómez A, Román-González L, Vidal A, López-Bigas N, Villanueva A, Esteller M, et al. The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma. Cell Death & Disease. 6: e1635. PMID 25675295 DOI: 10.1038/cddis.2014.594  1
2015 Villanueva A, Portela A, Sayols S, Battiston C, Hoshida Y, Méndez-González J, Imbeaud S, Letouzé E, Hernandez-Gea V, Cornella H, Pinyol R, Solé M, Fuster J, Zucman-Rossi J, Mazzaferro V, ... Esteller M, et al. DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma. Hepatology (Baltimore, Md.). 61: 1945-56. PMID 25645722 DOI: 10.1002/hep.27732  1
2015 Cornella H, Alsinet C, Sayols S, Zhang Z, Hao K, Cabellos L, Hoshida Y, Villanueva A, Thung S, Ward SC, Rodriguez-Carunchio L, Vila-Casadesús M, Imbeaud S, Lachenmayer A, Quaglia A, ... ... Esteller M, et al. Unique genomic profile of fibrolamellar hepatocellular carcinoma. Gastroenterology. 148: 806-18.e10. PMID 25557953 DOI: 10.1053/j.gastro.2014.12.028  1
2015 Stefansson OA, Moran S, Gomez A, Sayols S, Arribas-Jorba C, Sandoval J, Hilmarsdottir H, Olafsdottir E, Tryggvadottir L, Jonasson JG, Eyfjord J, Esteller M. A DNA methylation-based definition of biologically distinct breast cancer subtypes. Molecular Oncology. 9: 555-68. PMID 25468711 DOI: 10.1016/j.molonc.2014.10.012  1
2015 Sandoval J, Díaz-Lagares A, Salgado R, Servitje O, Climent F, Ortiz-Romero PL, Pérez-Ferriols A, Garcia-Muret MP, Estrach T, Garcia M, Nonell L, Esteller M, Pujol RM, Espinet B, Gallardo F. MicroRNA expression profiling and DNA methylation signature for deregulated microRNA in cutaneous T-cell lymphoma. The Journal of Investigative Dermatology. 135: 1128-37. PMID 25405321 DOI: 10.1038/jid.2014.487  1
2015 Wrage M, Hagmann W, Kemming D, Uzunoglu FG, Riethdorf S, Effenberger K, Westphal M, Lamszus K, Kim SZ, Becker N, Izbicki JR, Sandoval J, Esteller M, Pantel K, Risch A, et al. Identification of HERC5 and its potential role in NSCLC progression. International Journal of Cancer. Journal International Du Cancer. 136: 2264-72. PMID 25353388 DOI: 10.1002/ijc.29298  1
2015 Fernández AF, Bayón GF, Urdinguio RG, Toraño EG, García MG, Carella A, Petrus-Reurer S, Ferrero C, Martinez-Camblor P, Cubillo I, García-Castro J, Delgado-Calle J, Pérez-Campo FM, Riancho JA, Bueno C, ... ... Esteller M, et al. H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells. Genome Research. 25: 27-40. PMID 25271306 DOI: 10.1101/gr.169011.113  1
2015 Simó-Riudalbas L, Esteller M. Targeting the histone orthography of cancer: drugs for writers, erasers and readers. British Journal of Pharmacology. 172: 2716-32. PMID 25039449 DOI: 10.1111/bph.12844  1
2015 Nettersheim D, Jostes S, Sharma R, Schneider S, Hofmann A, Ferreira HJ, Hoffmann P, Kristiansen G, Esteller MB, Schorle H. BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma Plos Genetics. 11. DOI: 10.1371/journal.pgen.1005415  1
2015 Alizadeh AA, Aranda V, Bardelli A, Blanpain C, Bock C, Borowski C, Caldas C, Califano A, Doherty M, Elsner M, Esteller M, Fitzgerald R, Korbel JO, Lichter P, Mason CE, et al. Toward understanding and exploiting tumor heterogeneity Nature Medicine. 21: 846-853. DOI: 10.1038/nm.3915  1
2015 Martín-Subero JI, Esteller M. Epigenomic code Systems Biology of Cancer. 113-133. DOI: 10.1017/9780511979811.009  1
2015 Liz J, Esteller M. LncRNAs and microRNAs with a role in cancer development Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms. DOI: 10.1016/j.bbagrm.2015.06.015  1
2014 Viré E, Curtis C, Davalos V, Git A, Robson S, Villanueva A, Vidal A, Barbieri I, Aparicio S, Esteller M, Caldas C, Kouzarides T. The Breast Cancer Oncogene EMSY Represses Transcription of Antimetastatic microRNA miR-31. Molecular Cell. 54: 203. PMID 28898635 DOI: 10.1016/j.molcel.2014.03.041  0.36
2014 Stefansson OA, Esteller M. CARM1 and BAF155: an example of how chromatin remodeling factors can be relocalized and contribute to cancer. Breast Cancer Research : Bcr. 16: 307. PMID 25927994 DOI: 10.1186/bcr3657  1
2014 Yuan W, Xia Y, Bell CG, Yet I, Ferreira T, Ward KJ, Gao F, Loomis AK, Hyde CL, Wu H, Lu H, Liu Y, Small KS, Viñuela A, Morris AP, ... ... Esteller M, et al. An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins. Nature Communications. 5: 5719. PMID 25502755 DOI: 10.1038/ncomms6719  1
2014 Huertas-Martínez J, Rello-Varona S, Herrero-Martín D, Barrau I, García-Monclús S, Sáinz-Jaspeado M, Lagares-Tena L, Núñez-Álvarez Y, Mateo-Lozano S, Mora J, Roma J, Toran N, Moran S, López-Alemany R, Gallego S, ... Esteller M, et al. Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth. Oncotarget. 5: 9744-55. PMID 25313138  1
2014 Ambrogio C, Carmona FJ, Vidal A, Falcone M, Nieto P, Romero OA, Puertas S, Vizoso M, Nadal E, Poggio T, Sánchez-Céspedes M, Esteller M, Mulero F, Voena C, Chiarle R, et al. Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts. Cancer Research. 74: 5978-88. PMID 25217522 DOI: 10.1158/0008-5472.CAN-14-1606  1
2014 Andersen GS, Thybo T, Cederberg H, Oreši? M, Esteller M, Zorzano A, Carr B, Walker M, Cobb J, Clissmann C, O'Gorman DJ, Nolan JJ. The DEXLIFE study methods: identifying novel candidate biomarkers that predict progression to type 2 diabetes in high risk individuals. Diabetes Research and Clinical Practice. 106: 383-9. PMID 25125339 DOI: 10.1016/j.diabres.2014.07.025  1
2014 Carmona FJ, Davalos V, Vidal E, Gomez A, Heyn H, Hashimoto Y, Vizoso M, Martinez-Cardus A, Sayols S, Ferreira HJ, Sánchez-Mut JV, Morán S, Margelí M, Castella E, Berdasco M, ... ... Esteller M, et al. A comprehensive DNA methylation profile of epithelial-to-mesenchymal transition. Cancer Research. 74: 5608-19. PMID 25106427 DOI: 10.1158/0008-5472.CAN-13-3659  1
2014 Zaina S, Heyn H, Carmona FJ, Varol N, Sayols S, Condom E, Ramírez-Ruz J, Gomez A, Gonçalves I, Moran S, Esteller M. DNA methylation map of human atherosclerosis. Circulation. Cardiovascular Genetics. 7: 692-700. PMID 25091541 DOI: 10.1161/CIRCGENETICS.113.000441  1
2014 Ongen H, Andersen CL, Bramsen JB, Oster B, Rasmussen MH, Ferreira PG, Sandoval J, Vidal E, Whiffin N, Planchon A, Padioleau I, Bielser D, Romano L, Tomlinson I, Houlston RS, ... Esteller M, et al. Putative cis-regulatory drivers in colorectal cancer. Nature. 512: 87-90. PMID 25079323 DOI: 10.1038/nature13602  1
2014 Deplus R, Blanchon L, Rajavelu A, Boukaba A, Defrance M, Luciani J, Rothé F, Dedeurwaerder S, Denis H, Brinkman AB, Simmer F, Müller F, Bertin B, Berdasco M, Putmans P, ... ... Esteller M, et al. Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a. Cell Reports. 8: 743-53. PMID 25066127 DOI: 10.1016/j.celrep.2014.06.048  1
2014 Szczesna K, de la Caridad O, Petazzi P, Soler M, Roa L, Saez MA, Fourcade S, Pujol A, Artuch-Iriberri R, Molero-Luis M, Vidal A, Huertas D, Esteller M. Improvement of the Rett syndrome phenotype in a MeCP2 mouse model upon treatment with levodopa and a dopa-decarboxylase inhibitor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2846-56. PMID 24917201 DOI: 10.1038/npp.2014.136  1
2014 Liz J, Portela A, Soler M, Gómez A, Ling H, Michlewski G, Calin GA, Guil S, Esteller M. Regulation of pri-miRNA processing by a long noncoding RNA transcribed from an ultraconserved region. Molecular Cell. 55: 138-47. PMID 24910097 DOI: 10.1016/j.molcel.2014.05.005  1
2014 Aguilar H, Urruticoechea A, Halonen P, Kiyotani K, Mushiroda T, Barril X, Serra-Musach J, Islam A, Caizzi L, Di Croce L, Nevedomskaya E, Zwart W, Bostner J, Karlsson E, Pérez Tenorio G, ... ... Esteller M, et al. VAV3 mediates resistance to breast cancer endocrine therapy. Breast Cancer Research : Bcr. 16: R53. PMID 24886537 DOI: 10.1186/bcr3664  1
2014 Michailidi C, Soudry E, Brait M, Maldonado L, Jaffe A, Ili-Gangas C, Brebi-Mieville P, Perez J, Kim MS, Zhong X, Yang Q, Valle B, Meltzer SJ, Torbenson M, Esteller M, et al. Genome-wide and gene-specific epigenomic platforms for hepatocellular carcinoma biomarker development trials. Gastroenterology Research and Practice. 2014: 597164. PMID 24829571 DOI: 10.1155/2014/597164  1
2014 Ausió J, de Paz AM, Esteller M. MeCP2: the long trip from a chromatin protein to neurological disorders. Trends in Molecular Medicine. 20: 487-98. PMID 24766768 DOI: 10.1016/j.molmed.2014.03.004  1
2014 Ramnath N, Nadal E, Jeon CK, Sandoval J, Colacino J, Rozek LS, Christensen PJ, Esteller M, Beer DG, Kim SH. Epigenetic regulation of vitamin D metabolism in human lung adenocarcinoma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 473-82. PMID 24736069 DOI: 10.1097/JTO.0000000000000114  1
2014 Moran S, Vizoso M, Martinez-Cardús A, Gomez A, Matías-Guiu X, Chiavenna SM, Fernandez AG, Esteller M. Validation of DNA methylation profiling in formalin-fixed paraffin-embedded samples using the Infinium HumanMethylation450 Microarray. Epigenetics : Official Journal of the Dna Methylation Society. 9: 829-33. PMID 24732293 DOI: 10.4161/epi.28790  1
2014 Heyn H, Sayols S, Moutinho C, Vidal E, Sanchez-Mut JV, Stefansson OA, Nadal E, Moran S, Eyfjord JE, Gonzalez-Suarez E, Pujana MA, Esteller M. Linkage of DNA methylation quantitative trait loci to human cancer risk. Cell Reports. 7: 331-8. PMID 24703846 DOI: 10.1016/j.celrep.2014.03.016  1
2014 Lopez-Serra P, Marcilla M, Villanueva A, Ramos-Fernandez A, Palau A, Leal L, Wahi JE, Setien-Baranda F, Szczesna K, Moutinho C, Martinez-Cardus A, Heyn H, Sandoval J, Puertas S, Vidal A, ... ... Esteller M, et al. A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect. Nature Communications. 5: 3608. PMID 24699711 DOI: 10.1038/ncomms4608  1
2014 Court F, Camprubi C, Garcia CV, Guillaumet-Adkins A, Sparago A, Seruggia D, Sandoval J, Esteller M, Martin-Trujillo A, Riccio A, Montoliu L, Monk D. The PEG13-DMR and brain-specific enhancers dictate imprinted expression within the 8q24 intellectual disability risk locus. Epigenetics & Chromatin. 7: 5. PMID 24667089 DOI: 10.1186/1756-8935-7-5  1
2014 Petazzi P, Akizu N, García A, Estarás C, Martínez de Paz A, Rodríguez-Paredes M, Martínez-Balbás MA, Huertas D, Esteller M. An increase in MECP2 dosage impairs neural tube formation. Neurobiology of Disease. 67: 49-56. PMID 24657916 DOI: 10.1016/j.nbd.2014.03.009  1
2014 Martínez R, Carmona FJ, Vizoso M, Rohde V, Kirsch M, Schackert G, Ropero S, Paulus W, Barrantes A, Gomez A, Esteller M. DNA methylation alterations in grade II- and anaplastic pleomorphic xanthoastrocytoma. Bmc Cancer. 14: 213. PMID 24650279 DOI: 10.1186/1471-2407-14-213  1
2014 Melo SA, Esteller M. Disruption of microRNA nuclear transport in human cancer. Seminars in Cancer Biology. 27: 46-51. PMID 24607282 DOI: 10.1016/j.semcancer.2014.02.012  1
2014 Varela-Rey M, Iruarrizaga-Lejarreta M, Lozano JJ, Aransay AM, Fernandez AF, Lavin JL, Mósen-Ansorena D, Berdasco M, Turmaine M, Luka Z, Wagner C, Lu SC, Esteller M, Mirsky R, Jessen KR, et al. S-adenosylmethionine levels regulate the schwann cell DNA methylome. Neuron. 81: 1024-39. PMID 24607226 DOI: 10.1016/j.neuron.2014.01.037  1
2014 Romanelli V, Nakabayashi K, Vizoso M, Moran S, Iglesias-Platas I, Sugahara N, Simón C, Hata K, Esteller M, Court F, Monk D. Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer. Epigenetics : Official Journal of the Dna Methylation Society. 9: 783-90. PMID 24589629 DOI: 10.4161/epi.28323  1
2014 Viré E, Curtis C, Davalos V, Git A, Robson S, Villanueva A, Vidal A, Barbieri I, Aparicio S, Esteller M, Caldas C, Kouzarides T. The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31. Molecular Cell. 53: 806-18. PMID 24582497 DOI: 10.1016/j.molcel.2014.01.029  1
2014 Guo M, Jia Y, Yu Z, House MG, Esteller M, Brock MV, Herman JG. Epigenetic changes associated with neoplasms of the exocrine and endocrine pancreas. Discovery Medicine. 17: 67-73. PMID 24534469  1
2014 Sanchez-Mut JV, Aso E, Heyn H, Matsuda T, Bock C, Ferrer I, Esteller M. Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease. Hippocampus. 24: 363-8. PMID 24436131 DOI: 10.1002/hipo.22245  1
2014 Palau A, Perucho M, Esteller M, Buschbeck M. First Barcelona Conference on Epigenetics and Cancer. Epigenetics : Official Journal of the Dna Methylation Society. 9: 468-75. PMID 24413145 DOI: 10.4161/epi.27759  1
2014 Guillaumet-Adkins A, Richter J, Odero MD, Sandoval J, Agirre X, Catala A, Esteller M, Prósper F, Calasanz MJ, Buño I, Kwon M, Court F, Siebert R, Monk D. Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels. Journal of Hematology & Oncology. 7: 4. PMID 24405639 DOI: 10.1186/1756-8722-7-4  1
2014 Court F, Tayama C, Romanelli V, Martin-Trujillo A, Iglesias-Platas I, Okamura K, Sugahara N, Simón C, Moore H, Harness JV, Keirstead H, Sanchez-Mut JV, Kaneki E, Lapunzina P, Soejima H, ... ... Esteller M, et al. Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishment. Genome Research. 24: 554-69. PMID 24402520 DOI: 10.1101/gr.164913.113  1
2014 Bonifaci N, Colas E, Serra-Musach J, Karbalai N, Brunet J, Gómez A, Esteller M, Fernández-Taboada E, Berenguer A, Reventós J, Müller-Myhsok B, Amundadottir L, Duell EJ, Pujana MÀ. Integrating gene expression and epidemiological data for the discovery of genetic interactions associated with cancer risk. Carcinogenesis. 35: 578-85. PMID 24296589 DOI: 10.1093/carcin/bgt403  1
2014 Juliachs M, Muñoz C, Moutinho CA, Vidal A, Condom E, Esteller M, Graupera M, Casanovas O, Germà JR, Villanueva A, Viñals F. The PDGFRβ-AKT pathway contributes to CDDP-acquired resistance in testicular germ cell tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 658-67. PMID 24277456 DOI: 10.1158/1078-0432.CCR-13-1131  1
2014 Moutinho C, Martinez-Cardús A, Santos C, Navarro-Pérez V, Martínez-Balibrea E, Musulen E, Carmona FJ, Sartore-Bianchi A, Cassingena A, Siena S, Elez E, Tabernero J, Salazar R, Abad A, Esteller M. Epigenetic inactivation of the BRCA1 interactor SRBC and resistance to oxaliplatin in colorectal cancer. Journal of the National Cancer Institute. 106: djt322. PMID 24273214 DOI: 10.1093/jnci/djt322  1
2014 Subtil-Rodríguez A, Vázquez-Chávez E, Ceballos-Chávez M, Rodríguez-Paredes M, Martín-Subero JI, Esteller M, Reyes JC. The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes. Nucleic Acids Research. 42: 2185-96. PMID 24265227 DOI: 10.1093/nar/gkt1161  1
2014 Ferreira HJ, Heyn H, Garcia del Muro X, Vidal A, Larriba S, Muñoz C, Villanueva A, Esteller M. Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis. Epigenetics : Official Journal of the Dna Methylation Society. 9: 113-8. PMID 24247010 DOI: 10.4161/epi.27237  1
2014 Simó-Riudalbas L, Esteller M. Cancer genomics identifies disrupted epigenetic genes. Human Genetics. 133: 713-25. PMID 24104525 DOI: 10.1007/s00439-013-1373-5  1
2014 Iliou MS, da Silva-Diz V, Carmona FJ, Ramalho-Carvalho J, Heyn H, Villanueva A, Muñoz P, Esteller M. Impaired DICER1 function promotes stemness and metastasis in colon cancer. Oncogene. 33: 4003-15. PMID 24096488 DOI: 10.1038/onc.2013.398  1
2014 Rodriguez-Paredes M, Martinez de Paz A, Simó-Riudalbas L, Sayols S, Moutinho C, Moran S, Villanueva A, Vázquez-Cedeira M, Lazo PA, Carneiro F, Moura CS, Vieira J, Teixeira MR, Esteller M. Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis. Oncogene. 33: 2807-13. PMID 23770855 DOI: 10.1038/onc.2013.239  1
2014 Davalos V, Esteller M. Unraveling the complex network of interactions between noncoding RNAs and epigenetics in cancer Non-Coding Rnas and Cancer. 125-148. DOI: 10.1007/978-1-4614-8444-8_7  1
2013 Quintavalle C, Mangani D, Roscigno G, Romano G, Diaz-Lagares A, Iaboni M, Donnarumma E, Fiore D, De Marinis P, Soini Y, Esteller M, Condorelli G. MiR-221/222 target the DNA methyltransferase MGMT in glioma cells. Plos One. 8: e74466. PMID 24147153 DOI: 10.1371/journal.pone.0074466  1
2013 Sandoval J, Mendez-Gonzalez J, Nadal E, Chen G, Carmona FJ, Sayols S, Moran S, Heyn H, Vizoso M, Gomez A, Sanchez-Cespedes M, Assenov Y, Müller F, Bock C, Taron M, ... ... Esteller M, et al. A prognostic DNA methylation signature for stage I non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 4140-7. PMID 24081945 DOI: 10.1200/JCO.2012.48.5516  1
2013 Hernando-Herraez I, Prado-Martinez J, Garg P, Fernandez-Callejo M, Heyn H, Hvilsom C, Navarro A, Esteller M, Sharp AJ, Marques-Bonet T. Dynamics of DNA methylation in recent human and great ape evolution. Plos Genetics. 9: e1003763. PMID 24039605 DOI: 10.1371/journal.pgen.1003763  1
2013 Sanchez-Mut JV, Aso E, Panayotis N, Lott I, Dierssen M, Rabano A, Urdinguio RG, Fernandez AF, Astudillo A, Martin-Subero JI, Balint B, Fraga MF, Gomez A, Gurnot C, Roux JC, ... ... Esteller M, et al. DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease. Brain : a Journal of Neurology. 136: 3018-27. PMID 24030951 DOI: 10.1093/brain/awt237  1
2013 Heyn H, Moran S, Hernando-Herraez I, Sayols S, Gomez A, Sandoval J, Monk D, Hata K, Marques-Bonet T, Wang L, Esteller M. DNA methylation contributes to natural human variation. Genome Research. 23: 1363-72. PMID 23908385 DOI: 10.1101/gr.154187.112  1
2013 Stefansson OA, Esteller M. Epigenetic modifications in breast cancer and their role in personalized medicine. The American Journal of Pathology. 183: 1052-63. PMID 23899662 DOI: 10.1016/j.ajpath.2013.04.033  1
2013 Vizoso M, Esteller M. German-Catalan workshop on epigenetics and cancer. Epigenetics : Official Journal of the Dna Methylation Society. 8: 998-1003. PMID 23884202 DOI: 10.4161/epi.25856  1
2013 Lister R, Mukamel EA, Nery JR, Urich M, Puddifoot CA, Johnson ND, Lucero J, Huang Y, Dwork AJ, Schultz MD, Yu M, Tonti-Filippini J, Heyn H, Hu S, Wu JC, ... ... Esteller M, et al. Global epigenomic reconfiguration during mammalian brain development. Science (New York, N.Y.). 341: 1237905. PMID 23828890 DOI: 10.1126/science.1237905  1
2013 Heyn H, Méndez-González J, Esteller M. Epigenetic profiling joins personalized cancer medicine. Expert Review of Molecular Diagnostics. 13: 473-9. PMID 23782254 DOI: 10.1586/erm.13.36  1
2013 Carmona FJ, Azuara D, Berenguer-Llergo A, Fernández AF, Biondo S, de Oca J, Rodriguez-Moranta F, Salazar R, Villanueva A, Fraga MF, Guardiola J, Capellá G, Esteller M, Moreno V. DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer. Cancer Prevention Research (Philadelphia, Pa.). 6: 656-65. PMID 23694962 DOI: 10.1158/1940-6207.CAPR-12-0501  1
2013 Muñoz-Pinedo C, González-Suárez E, Portela A, Gentilella A, Esteller M. Exploiting tumor vulnerabilities: epigenetics, cancer metabolism and the mTOR pathway in the era of personalized medicine. Cancer Research. 73: 4185-9. PMID 23687347 DOI: 10.1158/0008-5472.CAN-13-0512  1
2013 Portela A, Liz J, Nogales V, Setién F, Villanueva A, Esteller M. DNA methylation determines nucleosome occupancy in the 5'-CpG islands of tumor suppressor genes. Oncogene. 32: 5421-8. PMID 23686312 DOI: 10.1038/onc.2013.162  1
2013 Heyn H, Esteller M. EZH2: an epigenetic gatekeeper promoting lymphomagenesis. Cancer Cell. 23: 563-5. PMID 23680141 DOI: 10.1016/j.ccr.2013.04.028  1
2013 Petazzi P, Sandoval J, Szczesna K, Jorge OC, Roa L, Sayols S, Gomez A, Huertas D, Esteller M. Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model. Rna Biology. 10: 1197-203. PMID 23611944 DOI: 10.4161/rna.24286  1
2013 Stuss DP, Cheema M, Ng MK, Martinez de Paz A, Williamson B, Missiaen K, Cosman JD, McPhee D, Esteller M, Hendzel M, Delaney K, Ausió J. Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domain. Nucleic Acids Research. 41: 4888-900. PMID 23558747 DOI: 10.1093/nar/gkt213  1
2013 Guerrero-Setas D, Pérez-Janices N, Blanco-Fernandez L, Ojer A, Cambra K, Berdasco M, Esteller M, Maria-Ruiz S, Torrea N, Guarch R. RASSF2 hypermethylation is present and related to shorter survival in squamous cervical cancer. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 26: 1111-22. PMID 23542458 DOI: 10.1038/modpathol.2013.32  1
2013 Espada J, Esteller M. Mouse models in epigenetics: insights in development and disease. Briefings in Functional Genomics. 12: 279-87. PMID 23426092 DOI: 10.1093/bfgp/elt005  1
2013 Amatu A, Sartore-Bianchi A, Moutinho C, Belotti A, Bencardino K, Chirico G, Cassingena A, Rusconi F, Esposito A, Nichelatti M, Esteller M, Siena S. Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2265-72. PMID 23422094 DOI: 10.1158/1078-0432.CCR-12-3518  1
2013 Berdasco M, Esteller M. Genetic syndromes caused by mutations in epigenetic genes. Human Genetics. 132: 359-83. PMID 23370504 DOI: 10.1007/s00439-013-1271-x  1
2013 Hernando H, Shannon-Lowe C, Islam AB, Al-Shahrour F, Rodríguez-Ubreva J, Rodríguez-Cortez VC, Javierre BM, Mangas C, Fernández AF, Parra M, Delecluse HJ, Esteller M, López-Granados E, Fraga MF, López-Bigas N, et al. The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion. Genome Biology. 14: R3. PMID 23320978 DOI: 10.1186/gb-2013-14-1-r3  1
2013 Heyn H, Moran S, Esteller M. Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome. Epigenetics : Official Journal of the Dna Methylation Society. 8: 28-33. PMID 23257959 DOI: 10.4161/epi.23366  1
2013 Øster B, Linnet L, Christensen LL, Thorsen K, Ongen H, Dermitzakis ET, Sandoval J, Moran S, Esteller M, Hansen TF, Lamy P, Laurberg S, Ørntoft TF, Andersen CL. Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer. International Journal of Cancer. Journal International Du Cancer. 132: 2303-15. PMID 23115050 DOI: 10.1002/ijc.27921  1
2013 Sandoval J, Heyn H, Méndez-González J, Gomez A, Moran S, Baiget M, Melo M, Badell I, Nomdedéu JF, Esteller M. Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia. British Journal of Haematology. 160: 406-9. PMID 23110451 DOI: 10.1111/bjh.12113  1
2013 Heyn H, Carmona FJ, Gomez A, Ferreira HJ, Bell JT, Sayols S, Ward K, Stefansson OA, Moran S, Sandoval J, Eyfjord JE, Spector TD, Esteller M. DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker. Carcinogenesis. 34: 102-8. PMID 23054610 DOI: 10.1093/carcin/bgs321  1
2013 Azuara D, Rodriguez-Moranta F, De Oca J, Sanjuan X, Guardiola J, Lobaton T, Wang A, Boadas J, Piqueras M, Monfort D, Galter S, Esteller M, Moreno V, Capellá G. Novel methylation panel for the early detection of neoplasia in high-risk ulcerative colitis and Crohn's colitis patients Inflammatory Bowel Diseases. 19: 165-173. PMID 22532293 DOI: 10.1002/ibd.22994  1
2013 Esteller M. Histone phosphorylation involved in diverse nuclear events Nucleus (United States). 4: 1. DOI: 10.4161/nucl.23781  1
2013 Rodríguez-Paredes M, Esteller M. The fundamental role of epigenetic regulation in normal and disturbed cell growth, differentiation, and stemness Epigenetic Therapy of Cancer: Preclinical Models and Treatment Approaches. 1-41. DOI: 10.1007/978-3-642-38404-2_1  1
2012 Ribel-Madsen R, Fraga MF, Jacobsen S, Bork-Jensen J, Lara E, Calvanese V, Fernandez AF, Friedrichsen M, Vind BF, Højlund K, Beck-Nielsen H, Esteller M, Vaag A, Poulsen P. Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes. Plos One. 7: e51302. PMID 23251491 DOI: 10.1371/journal.pone.0051302  1
2012 Rotili D, Tarantino D, Nebbioso A, Paolini C, Huidobro C, Lara E, Mellini P, Lenoci A, Pezzi R, Botta G, Lahtela-Kakkonen M, Poso A, Steinkühler C, Gallinari P, De Maria R, ... ... Esteller M, et al. Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells. Journal of Medicinal Chemistry. 55: 10937-47. PMID 23189967 DOI: 10.1021/jm3011614  1
2012 Mayol G, Martín-Subero JI, Ríos J, Queiros A, Kulis M, Suñol M, Esteller M, Gómez S, Garcia I, de Torres C, Rodríguez E, Galván P, Mora J, Lavarino C. DNA hypomethylation affects cancer-related biological functions and genes relevant in neuroblastoma pathogenesis. Plos One. 7: e48401. PMID 23144874 DOI: 10.1371/journal.pone.0048401  1
2012 Muñoz P, Iliou MS, Esteller M. Epigenetic alterations involved in cancer stem cell reprogramming. Molecular Oncology. 6: 620-36. PMID 23141800 DOI: 10.1016/j.molonc.2012.10.006  1
2012 Esteller M. Cancer, epigenetics and the Nobel Prizes. Molecular Oncology. 6: 565-6. PMID 23141798 DOI: 10.1016/j.molonc.2012.10.004  1
2012 Guil S, Esteller M. Cis-acting noncoding RNAs: friends and foes. Nature Structural & Molecular Biology. 19: 1068-75. PMID 23132386 DOI: 10.1038/nsmb.2428  1
2012 Heyn H, Ferreira HJ, Bassas L, Bonache S, Sayols S, Sandoval J, Esteller M, Larriba S. Epigenetic disruption of the PIWI pathway in human spermatogenic disorders. Plos One. 7: e47892. PMID 23112866 DOI: 10.1371/journal.pone.0047892  1
2012 Simmer F, Brinkman AB, Assenov Y, Matarese F, Kaan A, Sabatino L, Villanueva A, Huertas D, Esteller M, Lengauer T, Bock C, Colantuoni V, Altucci L, Stunnenberg HG. Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues. Epigenetics : Official Journal of the Dna Methylation Society. 7: 1355-67. PMID 23079744 DOI: 10.4161/epi.22562  1
2012 Krausz C, Sandoval J, Sayols S, Chianese C, Giachini C, Heyn H, Esteller M. Novel insights into DNA methylation features in spermatozoa: stability and peculiarities. Plos One. 7: e44479. PMID 23071498 DOI: 10.1371/journal.pone.0044479  1
2012 Stefansson OA, Villanueva A, Vidal A, Martí L, Esteller M. BRCA1 epigenetic inactivation predicts sensitivity to platinum-based chemotherapy in breast and ovarian cancer Epigenetics. 7: 1225-1229. PMID 23069641 DOI: 10.4161/epi.22561  1
2012 Berdasco M, Melguizo C, Prados J, Gómez A, Alaminos M, Pujana MA, Lopez M, Setien F, Ortiz R, Zafra I, Aranega A, Esteller M. DNA methylation plasticity of human adipose-derived stem cells in lineage commitment American Journal of Pathology. 181: 2079-2093. PMID 23031258 DOI: 10.1016/j.ajpath.2012.08.016  1
2012 Heyn H, Esteller M. DNA methylation profiling in the clinic: applications and challenges Nature Reviews. Genetics. 13: 679-692. PMID 22945394 DOI: 10.1038/nrg3270  1
2012 Stefansson OA, Villanueva A, Vidal A, Martí L, Esteller M. Re: A DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapy Journal of the National Cancer Institute. 104: 1514. PMID 22923512 DOI: 10.1093/jnci/djs363  1
2012 Vidal A, Muñoz C, Guillén MJ, Moretó J, Puertas S, Martínez-Iniesta M, Figueras A, Padullés L, García-Rodriguez FJ, Berdiel-Acer M, Pujana MA, Salazar R, Gil-Martin M, Martí L, Ponce J, ... ... Esteller M, et al. Lurbinectedin (PM01183), a new DNA minor groove binder, Inhibits growth of orthotopic primary graft of cisplatin-resistant epithelial ovarian cancer Clinical Cancer Research. 18: 5399-5411. PMID 22896654 DOI: 10.1158/1078-0432.CCR-12-1513  1
2012 Vizoso M, Esteller M. The activatory long non-coding RNA DBE-T reveals the epigenetic etiology of facioscapulohumeral muscular dystrophy Cell Research. 22: 1413-1415. PMID 22710800 DOI: 10.1038/cr.2012.93  1
2012 Heyn H, Li N, Ferreira HJ, Moran S, Pisano DG, Gomez A, Diez J, Sanchez-Mut JV, Setien F, Carmona FJ, Puca AA, Sayols S, Pujana MA, Serra-Musach J, Iglesias-Platas I, ... ... Esteller M, et al. Distinct DNA methylomes of newborns and centenarians. Proceedings of the National Academy of Sciences of the United States of America. 109: 10522-7. PMID 22689993 DOI: 10.1073/pnas.1120658109  1
2012 Guil S, Soler M, Portela A, Carrère J, Fonalleras E, Gómez A, Villanueva A, Esteller M. Intronic RNAs mediate EZH2 regulation of epigenetic targets Nature Structural and Molecular Biology. 19: 664-670. PMID 22659877 DOI: 10.1038/nsmb.2315  1
2012 Barrero MJ, Berdasco M, Paramonov I, Bilic J, Vitaloni M, Esteller M, Belmonte JCI. DNA hypermethylation in somatic cells correlates with higher reprogramming efficiency Stem Cells. 30: 1696-1702. PMID 22653871 DOI: 10.1002/stem.1138  1
2012 Ferreira HJ, Heyn H, Moutinho C, Esteller M. CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer Rna Biology. 9: 881-890. PMID 22617881 DOI: 10.4161/rna.19353  1
2012 Heyn H, Vidal E, Sayols S, Sanchez-Mut JV, Moran S, Medina I, Sandoval J, Simó-Riudalbas L, Szczesna K, Huertas D, Gatto S, Matarazzo MR, Dopazo J, Esteller M. Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient. Epigenetics : Official Journal of the Dna Methylation Society. 7: 542-50. PMID 22595875 DOI: 10.4161/epi.20523  1
2012 Sanchez-Mut JV, Huertas D, Esteller M. Aberrant epigenetic landscape in intellectual disability Progress in Brain Research. 197: 53-71. PMID 22541288 DOI: 10.1016/B978-0-444-54299-1.00004-2  1
2012 Stefansson OA, Esteller M. BRCA1 as a tumor suppressor linked to the regulation of epigenetic states: Keeping oncomiRs under control Breast Cancer Research. 14. PMID 22423979 DOI: 10.1186/bcr3119  1
2012 Sandoval J, Esteller M. Cancer epigenomics: beyond genomics. Current Opinion in Genetics & Development. 22: 50-5. PMID 22402447 DOI: 10.1016/j.gde.2012.02.008  1
2012 Adams D, Altucci L, Antonarakis SE, Ballesteros J, Beck S, Bird A, Bock C, Boehm B, Campo E, Caricasole A, Dahl F, Dermitzakis ET, Enver T, Esteller M, Estivill X, et al. BLUEPRINT to decode the epigenetic signature written in blood. Nature Biotechnology. 30: 224-6. PMID 22398613 DOI: 10.1038/nbt.2153  1
2012 Carmona FJ, Villanueva A, Vidal A, Muñoz C, Puertas S, Penin RM, Gomà M, Lujambio A, Piulats JM, Mesía R, Sánchez-Céspedes M, Manós M, Condom E, Eccles SA, Esteller M. Epigenetic disruption of cadherin-11 in human cancer metastasis Journal of Pathology. 228: 230-240. PMID 22374749 DOI: 10.1002/path.4011  1
2012 Casati L, Sendra R, Colciago A, Negri-Cesi P, Berdasco M, Esteller M, Celotti F. Polychlorinated biphenyls affect histone modification pattern in early development of rats: A role for androgen receptor-dependent modulation? Epigenomics. 4: 101-112. PMID 22332662 DOI: 10.2217/epi.11.110  1
2012 Berdasco M, Esteller M. Hot topics in epigenetic mechanisms of aging: 2011 Aging Cell. 11: 181-186. PMID 22321768 DOI: 10.1111/j.1474-9726.2012.00806.x  1
2012 oĹpez-nieva P, Vaquero C, Fernández-navarro P, González-sánchez L, Villa-morales M, Santos J, Esteller M, Fernández-piqueras J. EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas Carcinogenesis. 33: 452-458. PMID 22114070 DOI: 10.1093/carcin/bgr271  1
2012 Rubio A, Sánchez-Mut JV, García E, Velasquez ZD, Oliver J, Esteller M, Avila J. Epigenetic control of somatostatin and cortistatin expression by β amyloid peptide Journal of Neuroscience Research. 90: 13-20. PMID 21922516 DOI: 10.1002/jnr.22731  1
2012 Taniguchi H, Jacinto FV, Villanueva A, Fernandez AF, Yamamoto H, Carmona FJ, Puertas S, Marquez VE, Shinomura Y, Imai K, Esteller M. Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer Oncogene. 31: 1988-1994. PMID 21892211 DOI: 10.1038/onc.2011.387  1
2012 Davalos V, Moutinho C, Villanueva A, Boque R, Silva P, Carneiro F, Esteller M. Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis Oncogene. 31: 2062-2074. PMID 21874049 DOI: 10.1038/onc.2011.383  1
2012 Lopez-Serra P, Esteller M. DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer Oncogene. 31: 1609-1622. PMID 21860412 DOI: 10.1038/onc.2011.354  1
2012 Huertas D, Soler M, Moreto J, Villanueva A, Martinez A, Vidal A, Charlton M, Moffat D, Patel S, McDermott J, Owen J, Brotherton D, Krige D, Cuthill S, Esteller M. Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene. 31: 1408-18. PMID 21804608 DOI: 10.1038/onc.2011.335  1
2012 Fernandez AF, Assenov Y, Martin-Subero JI, Balint B, Siebert R, Taniguchi H, Yamamoto H, Hidalgo M, Tan AC, Galm O, Ferrer I, Sanchez-Cespedes M, Villanueva A, Carmona J, Sanchez-Mut JV, ... ... Esteller M, et al. A DNA methylation fingerprint of 1628 human samples. Genome Research. 22: 407-19. PMID 21613409 DOI: 10.1101/gr.119867.110  1
2012 Javier Carmona F, Esteller M. Dna methylation in early neoplasia Translational Pathology of Early Cancer. 101-111. DOI: 10.3233/978-1-61499-024-6-101  1
2012 Davalos V, Esteller M. Rolling the Dice to Discover the Role of DICER in Tumorigenesis Cancer Cell. 21: 717-719. DOI: 10.1016/j.ccr.2012.05.030  1
2012 Rosales C, Esteller M. Epigenetic mouse models Genetically Engineered Mice For Cancer Research: Design, Analysis, Pathways, Validation and Pre-Clinical Testing. 375-396. DOI: 10.1007/978-0-387-69805-2_18  1
2011 Rodríguez-Paredes M, Esteller M. A combined epigenetic therapy equals the efficacy of conventional chemotherapy in refractory advanced non-small cell lung cancer Cancer Discovery. 1: 557-559. PMID 22586680 DOI: 10.1158/2159-8290.CD-11-0271  1
2011 Jost KL, Rottach A, Milden M, Bertulat B, Becker A, Wolf P, Sandoval J, Petazzi P, Huertas D, Esteller M, Kremmer E, Leonhardt H, Cardoso MC. Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies. Plos One. 6: e26499. PMID 22140431 DOI: 10.1371/journal.pone.0026499  1
2011 Rangel-Salazar R, Wickström-Lindholm M, Aguilar-Salinas CA, Alvarado-Caudillo Y, Døssing KBV, Esteller M, Labourier E, Lund G, Nielsen FC, Rodríguez-Ríos D, Solís-Martínez MO, Wrobel K, Zaina S. Human native lipoprotein-induced de novo DNA methylation is associated with repression of inflammatory genes in THP-1 macrophages Bmc Genomics. 12. PMID 22118513 DOI: 10.1186/1471-2164-12-582  1
2011 Incoronato M, Urso L, Portela A, Laukkanen MO, Soini Y, Quintavalle C, Keller S, Esteller M, Condorelli G. Epigenetic Regulation of miR-212 Expression in Lung Cancer Plos One. 6. PMID 22110741 DOI: 10.1371/journal.pone.0027722  1
2011 Esteller M. Non-coding RNAs in human disease Nature Reviews Genetics. 12: 861-874. PMID 22094949 DOI: 10.1038/nrg3074  1
2011 Iliou MS, Lujambio A, Portela A, Brüstle O, Koch P, Andersson-Vincent PH, Sundström E, Hovatta O, Esteller M. Bivalent histone modifications in stem cells poise miRNA loci for CpG island hypermethylation in human cancer. Epigenetics : Official Journal of the Dna Methylation Society. 6: 1344-53. PMID 22048248 DOI: 10.4161/epi.6.11.18021  1
2011 Berdasco M, Esteller M. DNA methylation in stem cell renewal and multipotency Stem Cell Research and Therapy. 2. PMID 22041459 DOI: 10.1186/scrt83  1
2011 Léveillé N, Elkon R, Davalos V, Manoharan V, Hollingworth D, Oude Vrielink J, le Sage C, Melo CA, Horlings HM, Wesseling J, Ule J, Esteller M, Ramos A, Agami R. Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity Nature Communications. 2: 513. PMID 22027593 DOI: 10.1038/ncomms1519  1
2011 Carmona FJ, Esteller M. IDIBELL cancer conference on metastasis and angiogenesis Cancer Research. 71: 6097-6101. PMID 21933886 DOI: 10.1158/0008-5472.CAN-11-2180  1
2011 Mayor R, Muñoz M, Coolen MW, Custodio J, Esteller M, Clark SJ, Peinado MA. Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells. Epigenetics : Official Journal of the Dna Methylation Society. 6: 1138-48. PMID 21852760 DOI: 10.4161/epi.6.9.16066  1
2011 Espada J, Peinado H, Lopez-Serra L, Setién F, Lopez-Serra P, Portela A, Renart J, Carrasco E, Calvo M, Juarranz A, Cano A, Esteller M. Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context. Nucleic Acids Research. 39: 9194-205. PMID 21846773 DOI: 10.1093/nar/gkr658  1
2011 Wilop S, Fernandez AF, Jost E, Herman JG, Brümmendorf TH, Esteller M, Galm O. Array-based DNA methylation profiling in acute myeloid leukaemia British Journal of Haematology. 155: 65-72. PMID 21790528 DOI: 10.1111/j.1365-2141.2011.08801.x  1
2011 Vegliante MC, Royo C, Palomero J, Salaverria I, Balint B, Martín-Guerrero I, Agirre X, Lujambio A, Richter J, Xargay-Torrent S, Bea S, Hernandez L, Enjuanes A, Calasanz MJ, Rosenwald A, ... ... Esteller M, et al. Epigenetic activation of SOX11 in Lymphoid Neoplasms by Histone modifications Plos One. 6. PMID 21738649 DOI: 10.1371/journal.pone.0021382  1
2011 Javierre BM, Rodriguez-Ubreva J, Al-Shahrour F, Corominas M, Graña O, Ciudad L, Agirre X, Pisano DG, Valencia A, Roman-Gomez J, Calasanz MJ, Prosper F, Esteller M, Gonzalez-Sarmiento R, Ballestar E. Long-range epigenetic silencing associates with deregulation of Ikaros targets in colorectal cancer cells. Molecular Cancer Research : McR. 9: 1139-51. PMID 21737484 DOI: 10.1158/1541-7786.MCR-10-0515  1
2011 Stefansson OA, Esteller M. EZH2-mediated epigenetic repression of DNA repair in promoting breast tumor initiating cells Breast Cancer Research : Bcr. 13: 309. PMID 21672285  1
2011 Stefansson OA, Jonasson JG, Olafsdottir K, Hilmarsdottir H, Olafsdottir G, Esteller M, Johannsson OT, Eyfjord JE. CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer Epigenetics. 6: 638-649. PMID 21593597 DOI: 10.4161/epi.6.5.15667  1
2011 Sandoval J, Heyn H, Moran S, Serra-Musach J, Pujana MA, Bibikova M, Esteller M. Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics : Official Journal of the Dna Methylation Society. 6: 692-702. PMID 21593595 DOI: 10.4161/epi.6.6.16196  1
2011 Guerrero-Preston R, Soudry E, Acero J, Orera M, Moreno-López L, Macía-Colón G, Jaffe A, Berdasco M, Ili-Gangas C, Brebi-Mieville P, Fu Y, Engstrom C, Irizarry RA, Esteller M, Westra W, et al. NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva Cancer Prevention Research. 4: 1061-1072. PMID 21558411 DOI: 10.1158/1940-6207.CAPR-11-0006  1
2011 Simó-Riudalbas L, Melo SA, Esteller M. DNMT3B gene amplification predicts resistance to DNA demethylating drugs Genes Chromosomes and Cancer. 50: 527-534. PMID 21484930 DOI: 10.1002/gcc.20877  1
2011 Melo S, Villanueva A, Moutinho C, Davalos V, Spizzo R, Ivan C, Rossi S, Setien F, Casanovas O, Simo-Riudalbas L, Carmona J, Carrere J, Vidal A, Aytes A, Puertas S, ... ... Esteller M, et al. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proceedings of the National Academy of Sciences of the United States of America. 108: 4394-9. PMID 21368194 DOI: 10.1073/pnas.1014720108  1
2011 Hoppe R, Brauch H, Kroetz DL, Esteller M. Exploiting the complexity of the genome and transcriptome using pharmacogenomics towards personalized medicine. Genome Biology. 12: 301. PMID 21241526 DOI: 10.1186/gb-2011-12-1-301  1
2011 Guerrero D, Guarch R, Ojer A, Casas JM, Méndez-Meca C, Esteller M, Barba-Ramos E, Garcia-Bragado F, Puras A. Differential hypermethylation of genes in vulvar cancer and lichen sclerosus coexisting or not with vulvar cancer International Journal of Cancer. 128: 2853-2864. PMID 20734389 DOI: 10.1002/ijc.25629  1
2011 Melo SA, Esteller M. Dysregulation of microRNAs in cancer: Playing with fire Febs Letters. 585: 2087-2099. PMID 20708002 DOI: 10.1016/j.febslet.2010.08.009  1
2011 Esteller M. Epigenetic changes in cancer F1000 Biology Reports. 3. DOI: 10.3410/B3-9  1
2011 Esteller M. Cancer epigenetics for the 21st century: What's next? Genes and Cancer. 2: 604-606. DOI: 10.1177/1947601911423096  1
2011 Martín-Subero JI, Esteller M. Profiling epigenetic alterations in disease Advances in Experimental Medicine and Biology. 711: 162-177. DOI: 10.1007/978-1-4419-8216-2_12  1
2011 Sandoval J, Esteller M. Epigenetics and reinventing lamarck: Pioneer evolutionary scientist's ideas revisited in light of novel research findings Genetic Engineering and Biotechnology News. 31.  1
2010 Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, Fernandez AF, Davalos V, Villanueva A, Montoya G, Yamamoto H, Schwartz S, Esteller M. A genetic defect in exportin-5 traps precursor MicroRNAs in the nucleus of cancer cells Cancer Cell. 18: 303-315. PMID 20951941 DOI: 10.1016/j.ccr.2010.09.007  1
2010 Alvarez S, Suela J, Valencia A, Fernández A, Wunderlich M, Agirre X, Prósper F, Martín-Subero JI, Maiques A, Acquadro F, Rodriguez Perales S, Calasanz MJ, Roman-Gómez J, Siebert R, Mulloy JC, ... ... Esteller M, et al. DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia. Plos One. 5: e12197. PMID 20808941 DOI: 10.1371/journal.pone.0012197  1
2010 Urdinguio RG, Fernandez AF, Lopez-Nieva P, Rossi S, Huertas D, Kulis M, Liu CG, Croce C, Calin GA, Esteller M. Disrupted microrna expression caused by Mecp2 loss in a mouse model of Rett syndrome Epigenetics. 5: 656-663. PMID 20716963 DOI: 10.4161/epi.5.7.13055  1
2010 Fernandez AF, Esteller M. Viral epigenomes in human tumorigenesis Oncogene. 29: 1405-1420. PMID 20101211 DOI: 10.1038/onc.2009.517  1
2010 Javierre BM, Fernandez AF, Richter J, Al-Shahrour F, Martin-Subero JI, Rodriguez-Ubreva J, Berdasco M, Fraga MF, O'Hanlon TP, Rider LG, Jacinto FV, Lopez-Longo FJ, Dopazo J, Forn M, Peinado MA, ... ... Esteller M, et al. Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Research. 20: 170-9. PMID 20028698 DOI: 10.1101/gr.100289.109  1
2009 Taniguchi H, Fernández AF, Setién F, Ropero S, Ballestar E, Villanueva A, Yamamoto H, Imai K, Shinomura Y, Esteller M. Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies. Cancer Research. 69: 8447-54. PMID 19861541 DOI: 10.1158/0008-5472.CAN-09-0551  0.36
2009 Martinez R, Martin-Subero JI, Rohde V, Kirsch M, Alaminos M, Fernandez AF, Ropero S, Schockert G, Esteller M. A microarray-based DNA methylation study of glioblastoma multiforme Epigenetics. 4: 255-264. PMID 19550145 DOI: 10.4161/epi.9130  1
2009 Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, Calin GA, Rossi S, Fernandez AF, Carneiro F, Oliveira C, Ferreira B, Liu CG, Villanueva A, Capella G, Schwartz S, ... ... Esteller M, et al. A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nature Genetics. 41: 365-70. PMID 19219043 DOI: 10.1038/ng.317  1
2009 Fernandez AF, Rosales C, Lopez-Nieva P, Graña O, Ballestar E, Ropero S, Espada J, Melo SA, Lujambio A, Fraga MF, Pino I, Javierre B, Carmona FJ, Acquadro F, Steenbergen RD, ... ... Esteller M, et al. The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer. Genome Research. 19: 438-51. PMID 19208682 DOI: 10.1101/gr.083550.108  1
2009 Guil S, Esteller M. DNA methylomes, histone codes and miRNAs: tying it all together. The International Journal of Biochemistry & Cell Biology. 41: 87-95. PMID 18834952 DOI: 10.1016/j.biocel.2008.09.005  1
2008 Urdinguio RG, Lopez-Serra L, Lopez-Nieva P, Alaminos M, Diaz-Uriarte R, Fernandez AF, Esteller M. Mecp2-null mice provide new neuronal targets for Rett syndrome. Plos One. 3: e3669. PMID 18989361 DOI: 10.1371/journal.pone.0003669  1
2008 Berdasco M, Alcázar R, García-Ortiz MV, Ballestar E, Fernández AF, Roldán-Arjona T, Tiburcio AF, Altabella T, Buisine N, Quesneville H, Baudry A, Lepiniec L, Alaminos M, Rodríguez R, Lloyd A, ... ... Esteller M, et al. Promoter DNA hypermethylation and gene repression in undifferentiated Arabidopsis cells. Plos One. 3: e3306. PMID 18827894 DOI: 10.1371/journal.pone.0003306  1
2008 Calvanese V, Horrillo A, Hmadcha A, Suarez-Alvarez B, Fernandez AF, Lara E, Casado S, Menendez P, Bueno C, Garcia-Castro J, Rubio R, Lapunzina P, Alaminos M, Borghese L, Terstegge S, ... ... Esteller M, et al. Cancer genes hypermethylated in human embryonic stem cells. Plos One. 3: e3294. PMID 18820729 DOI: 10.1371/journal.pone.0003294  1
2008 Lujambio A, Calin GA, Villanueva A, Ropero S, Sánchez-Céspedes M, Blanco D, Montuenga LM, Rossi S, Nicoloso MS, Faller WJ, Gallagher WM, Eccles SA, Croce CM, Esteller M. A microRNA DNA methylation signature for human cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 13556-61. PMID 18768788 DOI: 10.1073/pnas.0803055105  0.36
2008 Vera E, Canela A, Fraga MF, Esteller M, Blasco MA. Epigenetic regulation of telomeres in human cancer Oncogene. 27: 6817-6833. PMID 18762811 DOI: 10.1038/onc.2008.289  1
2008 Fraga MF, Berdasco M, Ballestar E, Ropero S, Lopez-Nieva P, Lopez-Serra L, Martín-Subero JI, Calasanz MJ, Lopez de Silanes I, Setien F, Casado S, Fernandez AF, Siebert R, Stifani S, Esteller M. Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies. Cancer Research. 68: 4116-22. PMID 18519670 DOI: 10.1158/0008-5472.CAN-08-0085  1
2008 Gomez-Duran A, Ballestar E, Carvajal-Gonzalez JM, Marlowe JL, Puga A, Esteller M, Fernandez-Salguero PM. Recruitment of CREB1 and histone deacetylase 2 (HDAC2) to the mouse Ltbp-1 promoter regulates its constitutive expression in a dioxin receptor-dependent manner. Journal of Molecular Biology. 380: 1-16. PMID 18508077 DOI: 10.1016/j.jmb.2008.04.056  1
2008 Sánchez A, Setién F, Martinez N, Oliva JL, Herranz M, Fraga MF, Alaminos M, Esteller M, Rojas JM. Epigenetic inactivation of the ERK inhibitor Spry2 in B-cell diffuse lymphomas. Oncogene. 27: 4969-72. PMID 18427547 DOI: 10.1038/onc.2008.129  1
2008 Moore LE, Pfeiffer RM, Poscablo C, Real FX, Kogevinas M, Silverman D, García-Closas R, Chanock S, Tardón A, Serra C, Carrato A, Dosemeci M, García-Closas M, Esteller M, Fraga M, et al. Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study. The Lancet. Oncology. 9: 359-66. PMID 18339581 DOI: 10.1016/S1470-2045(08)70038-X  1
2007 Lujambio A, Ropero S, Ballestar E, Fraga MF, Cerrato C, Setién F, Casado S, Suarez-Gauthier A, Sanchez-Cespedes M, Git A, Gitt A, Spiteri I, Das PP, Caldas C, Miska E, ... Esteller M, et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Research. 67: 1424-9. PMID 17308079 DOI: 10.1158/0008-5472.CAN-06-4218  1
2007 Perdiguero E, Ruiz-Bonilla V, Gresh L, Hui L, Ballestar E, Sousa-Victor P, Baeza-Raja B, Jardí M, Bosch-Comas A, Esteller M, Caelles C, Serrano AL, Wagner EF, Muñoz-Cánoves P. Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. The Embo Journal. 26: 1245-56. PMID 17304211 DOI: 10.1038/sj.emboj.7601587  1
2007 Martinez R, Setien F, Voelter C, Casado S, Quesada MP, Schackert G, Esteller M. CpG island promoter hypermethylation of the pro-apoptotic gene caspase-8 is a common hallmark of relapsed glioblastoma multiforme. Carcinogenesis. 28: 1264-8. PMID 17272309 DOI: 10.1093/carcin/bgm014  1
2006 Gonzalo S, Jaco I, Fraga MF, Chen T, Li E, Esteller M, Blasco MA. DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nature Cell Biology. 8: 416-24. PMID 16565708 DOI: 10.1038/ncb1386  1
2006 Cebrian A, Pharoah PD, Ahmed S, Ropero S, Fraga MF, Smith PL, Conroy D, Luben R, Perkins B, Easton DF, Dunning AM, Esteller M, Ponder BA. Genetic variants in epigenetic genes and breast cancer risk. Carcinogenesis. 27: 1661-9. PMID 16501248 DOI: 10.1093/carcin/bgi375  1
2005 Gallagher WM, Bergin OE, Rafferty M, Kelly ZD, Nolan IM, Fox EJ, Culhane AC, McArdle L, Fraga MF, Hughes L, Currid CA, O'Mahony F, Byrne A, Murphy AA, Moss C, ... ... Esteller M, et al. Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies. Carcinogenesis. 26: 1856-67. PMID 15958521 DOI: 10.1093/carcin/bgi152  1
2005 Galaz S, Espada J, Stockert JC, Pacheco M, Sanz-Rodríguez F, Arranz R, Rello S, Cañete M, Villanueva A, Esteller M, Juarranz A. Loss of E-cadherin mediated cell-cell adhesion as an early trigger of apoptosis induced by photodynamic treatment. Journal of Cellular Physiology. 205: 86-96. PMID 15880654 DOI: 10.1002/jcp.20374  0.36
2004 Ropero S, Setien F, Espada J, Fraga MF, Herranz M, Asp J, Benassi MS, Franchi A, Patiño A, Ward LS, Bovee J, Cigudosa JC, Wim W, Esteller M. Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells. Human Molecular Genetics. 13: 2753-65. PMID 15385438 DOI: 10.1093/hmg/ddh298  1
2004 Ibanez de Caceres I, Battagli C, Esteller M, Herman JG, Dulaimi E, Edelson MI, Bergman C, Ehya H, Eisenberg BL, Cairns P. Tumor cell-specific BRCA1 and RASSF1A hypermethylation in serum, plasma, and peritoneal fluid from ovarian cancer patients. Cancer Research. 64: 6476-81. PMID 15374957 DOI: 10.1158/0008-5472.CAN-04-1529  1
2004 Paz MF, Yaya-Tur R, Rojas-Marcos I, Reynes G, Pollan M, Aguirre-Cruz L, García-Lopez JL, Piquer J, Safont MJ, Balaña C, Sanchez-Cespedes M, García-Villanueva M, Arribas L, Esteller M. CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4933-8. PMID 15297393 DOI: 10.1158/1078-0432.CCR-04-0392  1
2004 Douglas DB, Akiyama Y, Carraway H, Belinsky SA, Esteller M, Gabrielson E, Weitzman S, Williams T, Herman JG, Baylin SB. Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer. Cancer Research. 64: 1611-20. PMID 14996719 DOI: 10.1158/0008-5472.CAN-0318-2  1
2002 Lerma E, Esteller M, Herman JG, Prat J. Alterations of the p16INK4a/Rb/cyclin-D1 pathway in vulvar carcinoma, vulvar intraepithelial neoplasia, and lichen sclerosus Human Pathology. 33: 1120-1125. PMID 12454817 DOI: 10.1053/hupa.2002.129415  1
2001 Esteller M, Fraga MF, Guo M, Garcia-Foncillas J, Hedenfalk I, Godwin AK, Trojan J, Vaurs-Barrière C, Bignon YJ, Ramus S, Benitez J, Caldes T, Akiyama Y, Yuasa Y, Launonen V, et al. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis Human Molecular Genetics. 10: 3001-3007. PMID 11751682 DOI: 10.1093/hmg/10.26.3001  1
2001 Fleisher AS, Esteller M, Tamura G, Rashid A, Stine OC, Yin J, Zou TT, Abraham JM, Kong D, Nishizuka S, James SP, Wilson KT, Herman JG, Meltzer SJ. Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia. Oncogene. 20: 329-35. PMID 11313962 DOI: 10.1038/sj.onc.1204104  1
2001 Hedenfalk I, Duggan D, Chen Y, Radmacher M, Bittner M, Simon R, Meltzer P, Gusterson B, Esteller M, Kallioniemi OP, Wilfond B, Borg A, Trent J, Raffeld M, Yakhini Z, et al. Gene-expression profiles in hereditary breast cancer. The New England Journal of Medicine. 344: 539-48. PMID 11207349 DOI: 10.1056/NEJM200102223440801  1
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