Samira Parhizkar - Publications

Affiliations: 
Washington Univ. School Medicine 
Area:
Alzheimer's disease, Microglia, Sleep

22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bosch ME, Dodiya HB, Michalkiewicz J, Lee C, Shaik SM, Weigle IQ, Zhang C, Osborn J, Nambiar A, Patel P, Parhizkar S, Zhang X, Laury ML, Mondal P, Gomm A, et al. Correction: Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner. Molecular Neurodegeneration. 19: 70. PMID 39390529 DOI: 10.1186/s13024-024-00764-2  0.688
2024 Zatcepin A, Gnörich J, Rauchmann BS, Bartos LM, Wagner S, Franzmeier N, Malpetti M, Xiang X, Shi Y, Parhizkar S, Grosch M, Wind-Mark K, Kunte ST, Beyer L, Meyer C, et al. Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer's disease. Molecular Neurodegeneration. 19: 64. PMID 39238030 DOI: 10.1186/s13024-024-00752-6  0.646
2024 Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, et al. Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience. PMID 39143410 DOI: 10.1038/s41593-024-01752-x  0.706
2024 Bosch ME, Dodiya HB, Michalkiewicz J, Lee C, Shaik SM, Weigle IQ, Zhang C, Osborn J, Nambiar A, Patel P, Parhizkar S, Zhang X, Laury ML, Mondal P, Gomm A, et al. Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner. Molecular Neurodegeneration. 19: 18. PMID 38365827 DOI: 10.1186/s13024-023-00700-w  0.745
2023 Chen Y, Song S, Parhizkar S, Lord J, Zhu Y, Strickland MR, Wang C, Park J, Tabor GT, Jiang H, Li K, Davis AA, Yuede CM, Colonna M, Ulrich JD, et al. APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread. Cell. PMID 38086389 DOI: 10.1016/j.cell.2023.11.029  0.601
2023 Wang C, Nambiar A, Strickland MR, Lee C, Parhizkar S, Moore AC, Musiek ES, Ulrich JD, Holtzman DM. APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading. The Journal of Clinical Investigation. PMID 37279069 DOI: 10.1172/JCI169131  0.572
2023 Parhizkar S, Gent G, Chen Y, Rensing N, Gratuze M, Strout G, Sviben S, Tycksen E, Zhang Q, Gilmore PE, Sprung R, Malone J, Chen W, Remolina Serrano J, Bao X, et al. Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a -dependent manner in mice. Science Translational Medicine. 15: eade6285. PMID 37099634 DOI: 10.1126/scitranslmed.ade6285  0.705
2022 Parhizkar S, Holtzman DM. APOE mediated neuroinflammation and neurodegeneration in Alzheimer's disease. Seminars in Immunology. 101594. PMID 35232622 DOI: 10.1016/j.smim.2022.101594  0.601
2021 Joshi P, Riffel F, Kumar S, Villacampa N, Theil S, Parhizkar S, Haass C, Colonna M, Heneka MT, Arzberger T, Herms J, Walter J. TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits. Acta Neuropathologica Communications. 9: 168. PMID 34663480 DOI: 10.1186/s40478-021-01263-x  0.627
2021 Joshi P, Riffel F, Satoh K, Enomoto M, Qamar S, Scheiblich H, Villacampa N, Kumar S, Theil S, Parhizkar S, Haass C, Heneka MT, Fraser PE, St George-Hyslop P, Walter J. Differential interaction with TREM2 modulates microglial uptake of modified Aβ species. Glia. PMID 34427354 DOI: 10.1002/glia.24077  0.596
2021 Gratuze M, Chen Y, Parhizkar S, Jain N, Strickland MR, Serrano JR, Colonna M, Ulrich JD, Holtzman DM. Activated microglia mitigate Aβ-associated tau seeding and spreading. The Journal of Experimental Medicine. 218. PMID 34100905 DOI: 10.1084/jem.20210542  0.755
2021 Biechele G, Sebastian Monasor L, Wind K, Blume T, Parhizkar S, Arzberger T, Sacher C, Beyer L, Eckenweber F, Gildehaus FJ, von Ungern-Sternberg B, Willem M, Bartenstein P, Cumming P, Rominger A, et al. Glitter in the Darkness? Non-fibrillar β-amyloid Plaque Components Significantly Impact the β-amyloid PET Signal in Mouse Models of Alzheimer's Disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 34016733 DOI: 10.2967/jnumed.120.261858  0.564
2021 Colombo AV, Sadler RK, Llovera G, Singh V, Roth S, Heindl S, Sebastian Monasor L, Verhoeven A, Peters F, Parhizkar S, Kamp F, Gomez de Aguero M, MacPherson AJ, Winkler E, Herms J, et al. Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition. Elife. 10. PMID 33845942 DOI: 10.7554/eLife.59826  0.623
2020 Takalo M, Wittrahm R, Wefers B, Parhizkar S, Jokivarsi K, Kuulasmaa T, Mäkinen P, Martiskainen H, Wurst W, Xiang X, Marttinen M, Poutiainen P, Haapasalo A, Hiltunen M, Haass C. The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions. Molecular Neurodegeneration. 15: 52. PMID 32917267 DOI: 10.1186/S13024-020-00402-7  0.658
2020 Sacher C, Blume T, Beyer L, Biechele G, Sauerbeck J, Eckenweber F, Deussing M, Focke C, Parhizkar S, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Baumann K, Tahirovic S, Kleinberger G, et al. Asymmetry of fibrillar plaque burden in amyloid mouse models. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 32414948 DOI: 10.2967/Jnumed.120.242750  0.554
2020 Schlepckow K, Monroe KM, Kleinberger G, Cantuti-Castelvetri L, Parhizkar S, Xia D, Willem M, Werner G, Pettkus N, Brunner B, Sülzen A, Nuscher B, Hampel H, Xiang X, Feederle R, et al. Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region. Embo Molecular Medicine. e11227. PMID 32154671 DOI: 10.15252/Emmm.201911227  0.602
2019 Zhou Q, Mareljic N, Michaelsen M, Parhizkar S, Heindl S, Nuscher B, Farny D, Czuppa M, Schludi C, Graf A, Krebs S, Blum H, Feederle R, Roth S, Haass C, et al. Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. Embo Molecular Medicine. e10919. PMID 31858749 DOI: 10.15252/Emmm.201910919  0.591
2019 Götzl JK, Brendel M, Werner G, Parhizkar S, Sebastian Monasor L, Kleinberger G, Colombo AV, Deussing M, Wagner M, Winkelmann J, Diehl-Schmid J, Levin J, Fellerer K, Reifschneider A, Bultmann S, et al. Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism. Embo Molecular Medicine. PMID 31122931 DOI: 10.15252/Emmm.201809711  0.542
2019 Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, et al. Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience. PMID 30617257 DOI: 10.1038/S41593-018-0296-9  0.739
2017 Kleinberger G, Brendel M, Mracsko E, Wefers B, Groeneweg L, Xiang X, Focke C, Deußing M, Suárez-Calvet M, Mazaheri F, Parhizkar S, Pettkus N, Wurst W, Feederle R, Bartenstein P, et al. The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism. The Embo Journal. PMID 28559417 DOI: 10.15252/Embj.201796516  0.607
2016 Pardon MC, Yanez Lopez M, Yuchun D, Marjańska M, Prior M, Brignell C, Parhizkar S, Agostini A, Bai L, Auer DP, Faas HM. Magnetic Resonance Spectroscopy discriminates the response to microglial stimulation of wild type and Alzheimer's disease models. Scientific Reports. 6: 19880. PMID 26813748 DOI: 10.1038/Srep19880  0.371
2014 Ahmed Z, Cooper J, Murray TK, Garn K, McNaughton E, Clarke H, Parhizkar S, Ward MA, Cavallini A, Jackson S, Bose S, Clavaguera F, Tolnay M, Lavenir I, Goedert M, et al. A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity. Acta Neuropathologica. 127: 667-83. PMID 24531916 DOI: 10.1007/S00401-014-1254-6  0.389
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