Samira Parhizkar

Affiliations: 
Washington Univ. School Medicine 
Area:
Alzheimer's disease, Microglia, Sleep
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"Samira Parhizkar"
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Parents

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Christian Haass grad student 2014-2019
David M. Holtzman post-doc 2020-
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Publications

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Bosch ME, Dodiya HB, Michalkiewicz J, et al. (2024) Correction: Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner. Molecular Neurodegeneration. 19: 70
Zatcepin A, Gnörich J, Rauchmann BS, et al. (2024) Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer's disease. Molecular Neurodegeneration. 19: 64
Parhizkar S, Arzberger T, Brendel M, et al. (2024) Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience
Bosch ME, Dodiya HB, Michalkiewicz J, et al. (2024) Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner. Molecular Neurodegeneration. 19: 18
Chen Y, Song S, Parhizkar S, et al. (2023) APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread. Cell
Wang C, Nambiar A, Strickland MR, et al. (2023) APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading. The Journal of Clinical Investigation
Parhizkar S, Gent G, Chen Y, et al. (2023) Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a -dependent manner in mice. Science Translational Medicine. 15: eade6285
Parhizkar S, Holtzman DM. (2022) APOE mediated neuroinflammation and neurodegeneration in Alzheimer's disease. Seminars in Immunology. 101594
Joshi P, Riffel F, Kumar S, et al. (2021) TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits. Acta Neuropathologica Communications. 9: 168
Joshi P, Riffel F, Satoh K, et al. (2021) Differential interaction with TREM2 modulates microglial uptake of modified Aβ species. Glia
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