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High-probability grants
According to our matching algorithm, Catherine Auger is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
2000 — 2002 |
Auger, Catherine J |
F32Activity Code Description: To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in specified health-related areas. |
Steroid Action in a Vocal Control Circuit @ Johns Hopkins University
Sex steroid hormones, such as testosterone (T) and 17beta-estradiol (E2) are well known to regulate both behavior and physiology. Many of these effects require that the steroids act on the brain by finding to their steroid receptor proteins that are distributed throughout the brain. An important unanswered question facing the field of neuroendocrinology concerns how steroid action is coordinated at multiple levels. The vocal control system of songbirds is an excellent model system for such components of this circuit that are important in the motor output of song. These include telencephalic nucleic, brainstem nuclei, and the vocal production organ the syrinx. The telencephalic nuclei exhibit a hierarchal organization of motor controls. It is not known if gonadal hormones must act in all these individual nuclei and/or muscle groups simultaneously to produce the full complement of song and whether steroids have independent effects in these different structures. I will investigate steroid action in the song circuit with the selective administration of steroid receptor antagonists centrally and peripherally.
|
0.901 |
2006 — 2011 |
Marler, Catherine [⬀] Auger, Catherine |
N/AActivity Code Description: No activity code was retrieved: click on the grant title for more information |
Cross-Generational Transmission of Aggression: Behavioral, Hormonal and Neural Mechanisms @ University of Wisconsin-Madison
The goal of this project is to investigate the behavioral and neuroendocrine mechanisms that propagate aggression across generations through epigenetic mechanisms in a highly paternal and aggressive mouse. Fathers may be particularly important for impacting aggression of offspring during development and perhaps more so than mothers. This process occurs through paternal behaviors such as retrieval of pups, which increases aggression levels of adult offspring. Furthermore the father's behavior causes long term changes in the distribution of the neuropeptide vasopressin in the nervous system that may influence both aggressive and paternal behaviors. A series of behavioral, physiological and neural mechanisms will be tested for involvement in the propagation of aggression and paternal behavior across generations. Hormones such as testosterone and progesterone are likely to be involved in responsiveness to the social environment and are likely to interact with the network of brain areas involved in aggressive and parental behaviors. This research will help us to understand some of the basic mechanisms that are involved in propagating social behaviors across generations at both a behavioral and cellular level. Overall, there is a dearth of knowledge about the behavioral and biological mechanisms through which parental behavior exerts long-term, non-genetic influences on the development of offspring behavior. Furthermore, in both human and animal studies, the effects of paternal behavior on offspring have received much less attention than maternal behavior. The proposed research offers an opportunity to receive broad training experience for students bridging animal behavior and behavioral endocrinology. This project will offer undergraduate and graduate students unique research opportunities, and will promote training of underrepresented minorities.
|
1 |
2011 — 2015 |
Auger, Anthony [⬀] Auger, Catherine |
N/AActivity Code Description: No activity code was retrieved: click on the grant title for more information |
Progesterone, Vasopressin and Social Behavior in Adult Male Rats @ University of Wisconsin-Madison
A functional role for progesterone and its receptor in female behavior and physiology is fairly well established; however, the data on progesterone and progestin receptor (PR) function in males are relatively sparse. Although there are only a few studies examining the action of progesterone in males, the results confirm an exciting yet understudied role for progesterone and/or the progestin receptor in adult male behavior and physiology. The goal of this project is to test the hypothesis that progesterone impairs social behavior, specifically social memory/recognition and recently collected preliminary data strongly support this hypothesis in a male rodent model. This research is valuable as it will develop a framework for understanding the role that progesterone plays in influencing social behavior (i.e., social recognition) in males, and provide new molecular targets, such as the underlying steroid /neuropeptide interactions and epigenetic mechanisms, for understanding how social recognition is regulated. These studies will also aid in the understanding of which neural pathways in the brain become compromised in some disease states in which one?s ability to socially recognize other individuals is impaired. The current project will also provide a valuable opportunity for education and dissemination of knowledge. The training provided is designed to give back to the community by engaging students from elementary to graduate school, as well as increase participation of women and students from underrepresented backgrounds in all aspects of experimental science. The data and techniques used to gain these data will be shared with the scientific community, as well as disseminated to the public.
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1 |