Area:
Substance Abuse, Addiction
We are testing a new system for linking grants to scientists.
The funding information displayed below comes from the
NIH Research Portfolio Online Reporting Tools and the
NSF Award Database.
The grant data on this page is limited to grants awarded in the United States and is thus partial. It can nonetheless be used to understand how funding patterns influence mentorship networks and vice-versa, which has deep implications on how research is done.
You can help! If you notice any innacuracies, please
sign in and mark grants as correct or incorrect matches.
Sign in to see low-probability grants and correct any errors in linkage between grants and researchers.
High-probability grants
According to our matching algorithm, Collene Lawhorn is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
2006 — 2007 |
Lawhorn, Collene |
F31Activity Code Description: To provide predoctoral individuals with supervised research training in specified health and health-related areas leading toward the research degree (e.g., Ph.D.). |
The Role of Striosomes in Basal Ganglia Function @ Albert Einstein Col of Med Yeshiva Univ
[unreadable] DESCRIPTION (provided by applicant): The striatum has distinct mu opioid receptor rich clusters of cells called striosomes, which are embedded in an extrastriosomal matrix. Our long term goal is to determine the role of striosomes in health and disease. The specific hypothesis is that striosomes and their output pathways are functional units that select and organize complex movement sequences and their pathology contributes to symptoms of Huntington's disease. The hypothesis is based on reports (1) that striosomes are selectively vulnerable in Huntington's disease patients (Hedreen & Folstein, 1995), (2) striosomes show increase Fos immunoreactivity during repetetive movements (Canales & Graybiel, 2000) and (3) striosome volume postively correlates with a complex movement in a Huntington's disease mouse model (Lawhorn et al, 2005). The specific aims are to: 1 Test the hypothesis that striosomes are selectively damaged in a Huntington's disease mouse model, 2. Determine whether striosomes are necessary to perform a complex sequencing task and an accelerating rotarod task by lesioning the mu opiod receptor clusters of cells in the striatum, and 3. Determine a functional correlate of striosomes using 2-deoxyglucose autoradiography in normal behaving animals. [unreadable] [unreadable] [unreadable]
|
0.915 |