Muriel Darnaudery, PhD

Affiliations:	1999-2000		Instituto Ramon y Cajal/CSIC SPAIN
	2000-2010		Lille University FRANCE
	2010-	Nutrineuro, INRAE	Université de Bordeaux FRANCE

Area:

early life stress; depression; cognition ; HPA axis; medial Prefrontal cortex; motherhood; gut-brain axis

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"Muriel Darnaudery"

Bio:

Muriel Darnaudery is Professor of Neurosciences at Bordeaux University. earned her Ph.D. in neurosciences and pharmacology in the laboratory headed by Prof M Le Moal at the University of Bordeaux (France) in 1998. She subsequently joined the laboratory of the Prof Luis Miguel Garcia-Segura in the Insituto Ramon y Cajal (CSIC, Madrid, Spain), where she did her postdoctoral work. In 2000, Dr Muriel Darnaudery was appointed Associate Professor at the University of Lille (France) in the team of the Prof S Maccari. She was then promoted to Full Professor at the University of Bordeaux (France) in 2009. Dr Darnaudery is working on the hypothesis of the developmental origin of adult health and diseases using an integrative approach. Her research is dedicated to the exploration of the role of early-life environment, in particular early-life adversity (nutrition, maternal obesity, maternal diabetes, maternal stress) on brain functions and vulnerability to neuropsychiatric diseases in offspring. Her work shows that adverse early-life events (both during pre- and postnatal periods) increase the allostatic load and program the brain vulnerability to stress later in life. She also explores the causal role of gut-brain dysfunctions (gut microbiota dysbiosis and gut leakiness) in the emergence of deficits associated with early-life stress.
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