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Timothy J. Hagen, Ph.D.

Affiliations: 
1988 University of Wisconsin-Milwaukee, Milwaukee, WI 
 2010- Chemistry Northern Illinois University, DeKalb, IL, United States 
Area:
Medicinal Chemistry
Website:
https://www.niu.edu/chembio/about/directories/faculty/hagen.shtml
Google:
"Timothy Hagen"
Bio:

https://www.niu.edu/hagen/
https://scholar.google.com/citations?user=dpR1__MAAAAJ&hl=en

Mean distance: 8.39
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Parents

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James M. Cook grad student 1988 UW-Milwaukee
Robert H. Mazur post-doc 1988-1989

Children

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Zheng Zhang grad student Northern Illinois University
Amy Dalby grad student 2010-2011 Northern Illinois University
Phumvadee Wangtrakuldee grad student 2010-2015 Northern Illinois University
Michael Thompson grad student 2013-2015 Northern Illinois University
Joy Blain grad student 2011-2016 Northern Illinois University
Gashaw M Goshu grad student 2011-2016 Northern Illinois University
Travis Helgren grad student 2011-2016 Northern Illinois University
Brian Hartnett grad student 2012-2016 Northern Illinois University
Congling Chen grad student 2014-2016 Northern Illinois University
Jeremy Ryan Troxell grad student 2014-2016 Northern Illinois University

Collaborators

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Darren William Begley collaborator 2011-2014 Emerald Biosciences
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Publications

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Pierce PG, Hartnett BE, Laughlin TM, et al. (2024) Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis. Acta Crystallographica. Section F, Structural Biology Communications. 80: 43-51
DeBouver ND, Bolejack MJ, Esan TE, et al. (2023) Bacterial structural genomics target enabled by a recently discovered potent fungal acetyl-CoA synthetase inhibitor. Acta Crystallographica. Section F, Structural Biology Communications. 79: 137-143
Sharma I, Chen C, Daraji D, et al. (2023) Novel Inhibitors of Rickettsia prowazekii Methionine Aminopeptidase from the Malaria Box. Bioorganic & Medicinal Chemistry Letters. 129281
Blain JM, Grote DL, Watkins SM, et al. (2021) Structural and biophysical characterization of the Burkholderia pseudomallei IspF inhibitor L-tryptophan hydroxamate. Bioorganic & Medicinal Chemistry Letters. 48: 128273
Watkins SM, Ghose D, Blain JM, et al. (2019) Antibacterial activity of 2-amino-4-hydroxypyrimidine-5-carboxylates and binding to Burkholderia pseudomallei 2-C-methyl-d-erythritol-2,4-cyclodiphosphate synthase. Bioorganic & Medicinal Chemistry Letters. 126660
Gurney ME, Nugent RA, Mo X, et al. (2019) Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders. Journal of Medicinal Chemistry
Helgren TR, Seven ES, Chen C, et al. (2018) The identification of inhibitory compounds of Rickettsia prowazekii methionine aminopeptidase for antibacterial applications. Bioorganic & Medicinal Chemistry Letters
Helgren TR, Hagen TJ. (2017) Demonstration of AutoDock as an Educational Tool for Drug Discovery. Journal of Chemical Education. 94: 345-349
Helgren TR, Chen C, Wangtrakuldee P, et al. (2016) Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents. Bioorganic & Medicinal Chemistry
Goshu GM, Ghose D, Bain JM, et al. (2015) Synthesis and biological evaluation of pyrazolopyrimidines as potential antibacterial agents. Bioorganic & Medicinal Chemistry Letters
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