Jun-Hyuk Choi, Ph.D.

Affiliations: 
Biochemistry & Biophysics University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
DNA Repair
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"Jun-Hyuk Choi"
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Aziz Sancar grad student 2009 UNC Chapel Hill
 (Reconstitution of a human ATR-mediated DNA damage checkpoint response.)
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Publications

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Kim SH, Kim GH, Kemp MG, et al. (2022) TREX1 degrades the 3' end of the small DNA oligonucleotide products of nucleotide excision repair in human cells. Nucleic Acids Research
van Toorn M, Turkyilmaz Y, Han S, et al. (2022) Active DNA damage eviction by HLTF stimulates nucleotide excision repair. Molecular Cell
Baek S, Han S, Kang D, et al. (2018) Simultaneous detection of nucleotide excision repair events and apoptosis-induced DNA fragmentation in genotoxin-treated cells. Scientific Reports. 8: 2265
Song J, Kemp MG, Choi JH. (2016) Detection of the Excised, Damage-containing Oligonucleotide Products of Nucleotide Excision Repair in Human Cells. Photochemistry and Photobiology
Choi JH, Kim SY, Kim SK, et al. (2015) An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells: Nucleotide Excision Repair, DNA Damage Checkpoint, and Apoptosis. The Journal of Biological Chemistry
Kemp MG, Gaddameedhi S, Choi JH, et al. (2014) DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair. The Journal of Biological Chemistry. 289: 26574-83
Choi JH, Gaddameedhi S, Kim SY, et al. (2014) Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cells. Nucleic Acids Research. 42: e29
Hu J, Choi JH, Gaddameedhi S, et al. (2013) Nucleotide excision repair in human cells: fate of the excised oligonucleotide carrying DNA damage in vivo. The Journal of Biological Chemistry. 288: 20918-26
Choi JH, Lindsey-Boltz LA, Kemp M, et al. (2010) Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 13660-5
Lindsey-Boltz LA, Serçin O, Choi JH, et al. (2009) Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase. The Journal of Biological Chemistry. 284: 33107-14
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