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Dara E. Leto, Ph.D.

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
diabetes, receptors, signal transduction
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"Dara Leto"
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Alan R. Saltiel grad student 2011 University of Michigan
 (GTPase Regulatory Proteins in Insulin-Stimulated Glucose Transport.)

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Publications

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Walczak CP, Leto DE, Zhang L, et al. (2019) Ribosomal protein RPL26 is the principal target of UFMylation. Proceedings of the National Academy of Sciences of the United States of America
Leto DE, Morgens DW, Zhang L, et al. (2019) Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation. Molecular Cell. 73: 377-389.e11
van der Goot AT, Pearce MMP, Leto DE, et al. (2018) Redundant and Antagonistic Roles of XTP3B and OS9 in Decoding Glycan and Non-glycan Degrons in ER-Associated Degradation. Molecular Cell
Karunanithi S, Xiong T, Uhm M, et al. (2014) A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes. Molecular Biology of the Cell. 25: 3059-69
Mowers J, Uhm M, Reilly SM, et al. (2013) Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1. Elife. 2: e01119
Leto D, Uhm M, Williams A, et al. (2013) Negative regulation of the RalGAP complex by 14-3-3. The Journal of Biological Chemistry. 288: 9272-83
Mowers J, Uhm M, Reilly SM, et al. (2013) Author response: Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1 Elife
Leto D, Saltiel AR. (2012) Regulation of glucose transport by insulin: traffic control of GLUT4. Nature Reviews. Molecular Cell Biology. 13: 383-96
Chen XW, Leto D, Xiao J, et al. (2011) Exocyst function is regulated by effector phosphorylation. Nature Cell Biology. 13: 580-8
Chen XW, Leto D, Xiong T, et al. (2011) A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action. Molecular Biology of the Cell. 22: 141-52
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