Ilyas Yildirim, Ph.D.
Affiliations: | University of Rochester, Rochester, NY |
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"Ilyas Yildirim"Mean distance: 17.46 | S | N | B | C | P |
Parents
Sign in to add mentor| Nicholas P. Bigelow | grad student | 2008 | Rochester | |
| (Free energy calculations of RNA duplexes with tandem GA base pairs using the Thermodynamic Integration Approach.) | ||||
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Publications
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| Taghavi A, Baisden JT, Childs-Disney JL, et al. (2023) Conformational dynamics of RNA G4C2 and G2C4 repeat expansions causing ALS/FTD using NMR and molecular dynamics studies. Nucleic Acids Research |
| Wang KW, Riveros I, DeLoye J, et al. (2022) Dynamic Docking of Small Molecules Targeting RNA CUG Repeats Causing Myotonic Dystrophy Type 1 (DM1). Biophysical Journal |
| Taghavi A, Riveros I, Wales DJ, et al. (2022) Evaluating Geometric Definitions of Stacking for RNA Dinucleoside Monophosphates Using Molecular Mechanics Calculations. Journal of Chemical Theory and Computation. 18: 3637-3653 |
| Taghavi A, Yildirim I. (2022) Computational Investigation of Bending Properties of RNA AUUCU, CCUG, CAG, and CUG Repeat Expansions Associated With Neuromuscular Disorders. Frontiers in Molecular Biosciences. 9: 830161 |
| Ursu A, Baisden JT, Bush JA, et al. (2021) A Small Molecule Exploits Hidden Structural Features within the RNA Repeat Expansion That Causes c9ALS/FTD and Rescues Pathological Hallmarks. Acs Chemical Neuroscience. 12: 4076-4089 |
| Vezina-Dawod S, Angelbello AJ, Choudhary S, et al. (2021) Massively Parallel Optimization of the Linker Domain in Small Molecule Dimers Targeting a Toxic r(CUG) Repeat Expansion. Acs Medicinal Chemistry Letters. 12: 907-914 |
| Suresh BM, Li W, Zhang P, et al. (2020) A general fragment-based approach to identify and optimize bioactive ligands targeting RNA. Proceedings of the National Academy of Sciences of the United States of America |
| Ursu A, Wang KW, Bush JA, et al. (2020) Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTD. Acs Chemical Biology |
| Angelbello AJ, Benhamou RI, Rzuczek SG, et al. (2020) A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome Complex. Cell Chemical Biology |
| Haniff HS, Knerr L, Liu X, et al. (2020) Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions. Nature Chemistry |