Christopher L. McClendon, Ph.D.

Institution:
University of California, San Francisco, San Francisco, CA
Area:
molecular recognition
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"Christopher McClendon"
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Parents

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James A. Wells grad student 2011 UCSF
 (Correlated Motions and Allostery.)
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Publications

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Schmidt D, Boehm M, McClendon CL, et al. (2019) Cosolvent-enhanced Sampling and Unbiased Identification of Cryptic Pockets Suitable for Structure-based Drug Design. Journal of Chemical Theory and Computation
Pfleger C, Minges A, Boehm M, et al. (2017) Ensemble- and rigidity theory-based perturbation approach to analyze dynamic allostery. Journal of Chemical Theory and Computation
Kim J, Ahuja LG, Chao FA, et al. (2017) A dynamic hydrophobic core orchestrates allostery in protein kinases. Science Advances. 3: e1600663
Ahuja LG, Kornev AP, McClendon CL, et al. (2017) Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer. Proceedings of the National Academy of Sciences of the United States of America
Meharena HS, Fan X, Ahuja LG, et al. (2016) Decoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein Kinases. Plos Biology. 14: e2000127
Meng H, McClendon CL, Dai Z, et al. (2015) Discovery of Novel 15-Lipoxygenase Activators To Shift the Human Arachidonic Acid Metabolic Network toward Inflammation Resolution. Journal of Medicinal Chemistry
Hasnain S, McClendon CL, Tremont Hsu M, et al. (2015) A Computational Model for E. coli Cytoplasm: Diffusion and Hydrodynamics Biophysical Journal. 108: 116a-117a
Srivastava AK, McDonald LR, Cembran A, et al. (2014) Synchronous opening and closing motions are essential for cAMP-dependent protein kinase A signaling. Structure (London, England : 1993). 22: 1735-43
McClendon CL, Kornev AP, Gilson MK, et al. (2014) Dynamic architecture of a protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 111: E4623-31
Hasnain S, McClendon CL, Hsu MT, et al. (2014) A new coarse-grained model for E. coli cytoplasm: accurate calculation of the diffusion coefficient of proteins and observation of anomalous diffusion. Plos One. 9: e106466
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