Jason C. Parrish, Ph.D.
Affiliations: | Purdue University, West Lafayette, IN, United States |
Area:
Dopamine and Serotonin AgonistsGoogle:
"Jason Parrish"Mean distance: 18.16 (cluster 11)
Parents
Sign in to add mentor| David E. Nichols | grad student | 2006 | Purdue | |
| (Toward a molecular understanding of hallucinogen action.) | ||||
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Publications
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| Parrish JC, Nichols DE. (2006) Serotonin 5-HT(2A) receptor activation induces 2-arachidonoylglycerol release through a phospholipase c-dependent mechanism. Journal of Neurochemistry. 99: 1164-75 |
| Braden MR, Parrish JC, Naylor JC, et al. (2006) Molecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists. Molecular Pharmacology. 70: 1956-64 |
| McLean TH, Parrish JC, Braden MR, et al. (2006) 1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agonists. Journal of Medicinal Chemistry. 49: 5794-803 |
| McLean TH, Chambers JJ, Parrish JC, et al. (2006) C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor. Journal of Medicinal Chemistry. 49: 4269-74 |
| Parrish JC, Braden MR, Gundy E, et al. (2005) Differential phospholipase C activation by phenylalkylamine serotonin 5-HT 2A receptor agonists. Journal of Neurochemistry. 95: 1575-84 |
| Jain RP, Pettersson HI, Zhang J, et al. (2004) Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro. Journal of Medicinal Chemistry. 47: 6113-6 |
| Kurrasch-Orbaugh DM, Parrish JC, Watts VJ, et al. (2003) A complex signaling cascade links the serotonin2A receptor to phospholipase A2 activation: the involvement of MAP kinases. Journal of Neurochemistry. 86: 980-91 |
| Chambers JJ, Parrish JC, Jensen NH, et al. (2003) Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT(2A/2C) receptor ligands. Journal of Medicinal Chemistry. 46: 3526-35 |