Nsikan E. Akpan, Ph.D.
Affiliations: | Pathobiology and Molecular Medicine | Columbia University, New York, NY |
Area:
Neuronal ApoptosisGoogle:
"Nsikan Akpan"Mean distance: 18.45 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Carol M. Troy | grad student | 2013 | Columbia | |
| (The Intrinsic Caspase Death Pathway in Stroke Neurodegeneration.) | ||||
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Publications
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| Lee L, Dale E, Staniszewski A, et al. (2014) Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease. Scientific Reports. 4: 7190 |
| Blanch RJ, Ahmed Z, Thompson AR, et al. (2014) Caspase-9 mediates photoreceptor death after blunt ocular trauma. Investigative Ophthalmology & Visual Science. 55: 6350-7 |
| Vigneswara V, Akpan N, Berry M, et al. (2014) Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated JAK/STAT signalling. Brain : a Journal of Neurology. 137: 1656-75 |
| Akpan N, Troy CM. (2013) Caspase inhibitors: prospective therapies for stroke. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 19: 129-36 |
| Tamayev R, Akpan N, Arancio O, et al. (2012) Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection. Molecular Neurodegeneration. 7: 60 |
| Akpan N, Serrano-Saiz E, Zacharia BE, et al. (2011) Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8894-904 |
| Troy CM, Akpan N, Jean YY. (2011) Regulation of caspases in the nervous system implications for functions in health and disease. Progress in Molecular Biology and Translational Science. 99: 265-305 |
| Ribe EM, Serrano-Saiz E, Akpan N, et al. (2008) Mechanisms of neuronal death in disease: defining the models and the players. The Biochemical Journal. 415: 165-82 |
| Akpan N, Caradonna K, Chuenkova MV, et al. (2008) Chagas' disease parasite-derived neurotrophic factor activates cholinergic gene expression in neuronal PC12 cells. Brain Research. 1217: 195-202 |