Eveline S. Arnold, Ph.D.

Biomedical Sciences

Don Cleveland	grad student	2012	UCSD
(ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor disease without aggregation or loss of nuclear TDP-43.)

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McCormack NM, Abera MB, Arnold ES, et al. (2021) A high-throughput genome-wide RNAi screen identifies modifiers of survival motor neuron protein. Cell Reports. 35: 109125
Arnold ES, Fischbeck KH. (2018) Spinal muscular atrophy. Handbook of Clinical Neurology. 148: 591-601
Ditsworth D, Maldonado M, McAlonis-Downes M, et al. (2017) Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis. Acta Neuropathologica
Foran E, Kwon DY, Nofziger JH, et al. (2016) CNS uptake of bortezomib is enhanced by P-glycoprotein inhibition: Implications for spinal muscular atrophy. Neurobiology of Disease
Mitchell JC, Constable R, So E, et al. (2015) Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS. Acta Neuropathologica Communications. 3: 36
Arnold ES, Ling SC, Huelga SC, et al. (2013) ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proceedings of the National Academy of Sciences of the United States of America. 110: E736-45