David M. McKean, Ph.D.
Affiliations: | 2010 | University of Colorado Anschutz Medical Campus, Denver, Aurora, CO |
Area:
DevelopmentGoogle:
"David McKean"Mean distance: 19.37 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Lee Niswander | grad student | 2010 | University of Colorado, Denver | |
| (Cripto links GPI biosynthesis and TGFb signaling in forebrain development and holoprosencephaly.) | ||||
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Publications
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| Engelhardt D, Marean A, McKean D, et al. (2024) RSG1 is required for cilia-dependent neural tube closure. Genesis (New York, N.Y. : 2000). 62: e23602 |
| Onoue K, Wakimoto H, Jiang J, et al. (2021) Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Mutation. Frontiers in Cardiovascular Medicine. 8: 639148 |
| Hsieh A, Morton SU, Willcox JAL, et al. (2020) EM-mosaic detects mosaic point mutations that contribute to congenital heart disease. Genome Medicine. 12: 42 |
| Jang MY, Tai AC, Patel PN, et al. (2019) Abstract 467: Identification of Novel Pathogenic Mutations in Non-Canonical RNA Splice Sites in Congenital Heart Disease Circulation Research. 125 |
| Jang MY, Pereira AC, McKean DM, et al. (2019) Abstract 210: Transcriptomic Changes During Induced Pluripotent Stem Cell-derived Neural Crest Cell Differentiation Highlight Genes Involved in Endocardial Cushion and Cardiac Outflow Tract Development Circulation Research. 125 |
| DeLaughter DM, Bick AG, Wakimoto H, et al. (2016) Single-Cell Resolution of Temporal Gene Expression during Heart Development. Developmental Cell |
| McKean DM, Homsy J, Wakimoto H, et al. (2016) Loss of RNA expression and allele-specific expression associated with congenital heart disease. Nature Communications. 7: 12824 |
| Homsy J, Zaidi S, Shen Y, et al. (2015) De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies. Science (New York, N.Y.). 350: 1262-6 |
| van den Boogaard M, Smemo S, Burnicka-Turek O, et al. (2014) A common genetic variant within SCN10A modulates cardiac SCN5A expression. The Journal of Clinical Investigation. 124: 1844-52 |
| Christodoulou DC, Wakimoto H, Onoue K, et al. (2014) 5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy. The Journal of Clinical Investigation. 124: 1364-70 |