Artis Klapars, Ph.D.

Affiliations: 
2000 University of Wisconsin, Madison, Madison, WI 
Area:
organic synthesis
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"Artis Klapars"
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Edwin Vedejs grad student 2000 UW Madison
 (Enantiocontrolled synthesis of an aziridinomitosene.)
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Publications

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Zultanski SL, Kuhl N, Zhong W, et al. (2020) Mechanistic Understanding of a Robust and Scalable Synthesis of Per(6-deoxy-6-halo)cyclodextrins, Versatile Intermediates for Cyclodextrin Modification Organic Process Research & Development
DiRocco DA, Ji Y, Sherer EC, et al. (2017) A multifunctional catalyst that stereoselectively assembles prodrugs. Science (New York, N.Y.). 356: 426-430
Simmons B, Liu Z, Klapars A, et al. (2017) Mechanism-Based Solution to the ProTide Synthesis Problem: Selective Access to Sofosbuvir, Acelarin, and INX-08189. Organic Letters
Hyde AM, Liu Z, Kosjek B, et al. (2016) Synthesis of the GPR40 Partial Agonist MK-8666 through a Kinetically Controlled Dynamic Enzymatic Ketone Reduction. Organic Letters
Chung JY, Shevlin M, Klapars A, et al. (2016) Asymmetric Synthesis of N-Boc-(R)-Silaproline via Rh-Catalyzed Intramolecular Hydrosilylation of Dehydroalanine and Continuous Flow N-Alkylation. Organic Letters
Limanto J, Ashley ER, Yin J, et al. (2014) A highly efficient asymmetric synthesis of vernakalant. Organic Letters. 16: 2716-9
Mangion IK, Chen CY, Li H, et al. (2014) Enantioselective synthesis of an HCV NS5a antagonist. Organic Letters. 16: 2310-3
Maddess ML, Scott JP, Alorati A, et al. (2014) Enantioselective synthesis of a highly substituted tetrahydrofluorene derivative as a potent and selective estrogen receptor beta agonist Organic Process Research and Development. 18: 528-538
Barker G, McGrath JL, Klapars A, et al. (2011) Enantioselective, palladium-catalyzed α-arylation of N-Boc pyrrolidine: in situ react IR spectroscopic monitoring, scope, and synthetic applications. The Journal of Organic Chemistry. 76: 5936-53
Yasuda N, Klapars A, Kohmura Y, et al. (2011) Asymmetric synthesis of a potent hNK-1 receptor antagonist Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 69: 579-587
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