Thomas H. Pillow, Ph.D.
Affiliations: | 2009 | Stanford University, Palo Alto, CA |
Area:
Organic, Organometallic, Bioorganic, and Medicinal ChemistryGoogle:
"Thomas Pillow"Mean distance: 7.91 | S | N | B | C | P |
Parents
Sign in to add mentor| Paul A. Wender | grad student | 2009 | Stanford | |
| (The design, synthesis, and evaluation of novel drug delivery systems.) | ||||
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Publications
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| Clardy SM, Uttard A, Du B, et al. (2023) Site-specific Dolasynthen antibody-drug conjugates exhibit consistent pharmacokinetic profiles across a wide range of drug to antibody ratios. Molecular Cancer Therapeutics |
| Pillow T. (2022) ortho-Quinone drugs go pro. Nature Chemistry. 14: 719-720 |
| Zacharias N, Podust VN, Kajihara KK, et al. (2022) A homogeneous high-DAR antibody-drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides. Chemical Science. 13: 3147-3160 |
| Vollmar BS, Frantz C, Schutten MM, et al. (2021) A Novel Calicheamicin Antibody-Drug Conjugate with Improved Properties. Molecular Cancer Therapeutics |
| Dragovich PS, Pillow TH, Blake RA, et al. (2021) Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy. Journal of Medicinal Chemistry |
| Dragovich PS, Pillow TH, Blake RA, et al. (2021) Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties. Journal of Medicinal Chemistry |
| Dela Cruz Chuh J, Go M, Chen Y, et al. (2021) Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response. Mabs. 13: 1862452 |
| Staben LR, Chen J, Cruz-Chuh JD, et al. (2020) Systematic Variation of Pyrrolobenzodiazepine (PBD)-dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug Conjugates. Journal of Medicinal Chemistry |
| Fourie-O'Donohue A, Chu PY, Dela Cruz Chuh J, et al. (2020) Improved translation of stability for conjugated antibodies using an in vitro whole blood assay. Mabs. 12: 1715705 |
| Pillow TH, Adhikari P, Blake RA, et al. (2020) Front Cover: Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity (ChemMedChem 1/2020) Chemmedchem. 15: 1-1 |