Antonietta M. Lillo, Ph.D.

Affiliations: 
2002 Brown University, Providence, RI 
Area:
Chemistry, Enzymology and Molecular Genetics of Natural Products Biosynthesis
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"Antonietta Lillo"
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David E. Cane grad student 2002 Brown
 (Investigation of mevalonate-independent biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).)
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Publications

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Richard SB, Lillo AM, Tetzlaff CN, et al. (2004) Kinetic analysis of Escherichia coli 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase, wild type and mutants, reveals roles of active site amino acids. Biochemistry. 43: 12189-97
Lillo AM, Tetzlaff CN, Sangari FJ, et al. (2003) Functional expression and characterization of EryA, the erythritol kinase of Brucella abortus, and enzymatic synthesis of L-erythritol-4-phosphate. Bioorganic & Medicinal Chemistry Letters. 13: 737-9
Richard SB, Ferrer JL, Bowman ME, et al. (2002) Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway. The Journal of Biological Chemistry. 277: 8667-72
Richard SB, Bowman ME, Kwiatkowski W, et al. (2001) Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis. Nature Structural Biology. 8: 641-8
Cane DE, Chow C, Lillo A, et al. (2001) Molecular cloning, expression and characterization of the first three genes in the mevalonate-independent isoprenoid pathway in Streptomyces coelicolor. Bioorganic & Medicinal Chemistry. 9: 1467-77
Cane DE, Chow C, Lillo A, et al. (2001) Erratum to “Molecular cloning, expression and characterization of the first three genes in the mevalonate-Independent isoprenoid pathway in Streptomyces Coelicolor” [Bioorg. Med. Chem. 9 (2001) 1467] Bioorganic & Medicinal Chemistry. 9: 2519
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