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Laura E. Strong, Ph.D.

Affiliations: 
2000 University of Wisconsin, Madison, Madison, WI 
Area:
Biomolecular recognition
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"Laura Strong"
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Laura Lee Kiessling grad student 2000 UW Madison
 (Design, synthesis and study of multivalent ligands.)

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Rutkoski TJ, Kink JA, Strong LE, et al. (2011) Site-specific PEGylation endows a mammalian ribonuclease with antitumor activity. Cancer Biology & Therapy. 12: 208-14
Rutkoski TJ, Kink JA, Strong LE, et al. (2010) Antitumor activity of ribonuclease multimers created by site-specific covalent tethering. Bioconjugate Chemistry. 21: 1691-702
Kiessling LL, Gestwicki JE, Strong LE. (2006) Synthetic multivalent ligands as probes of signal transduction. Angewandte Chemie (International Ed. in English). 45: 2348-68
Kiessling LL, Gestwicki JE, Strong LE. (2006) Synthetische multivalente Liganden als Sonden für die Signaltransduktion Angewandte Chemie. 118: 2408-2429
Gestwicki JE, Cairo CW, Strong LE, et al. (2002) Influencing receptor-ligand binding mechanisms with multivalent ligand architecture. Journal of the American Chemical Society. 124: 14922-33
Lamanna AC, Gestwicki JE, Strong LE, et al. (2002) Conserved amplification of chemotactic responses through chemoreceptor interactions. Journal of Bacteriology. 184: 4981-7
Gestwicki JE, Strong LE, Cairo CW, et al. (2002) Cell aggregation by scaffolded receptor clusters. Chemistry & Biology. 9: 163-9
Gestwicki JE, Strong LE, Borchardt SL, et al. (2001) Designed potent multivalent chemoattractants for Escherichia coli. Bioorganic & Medicinal Chemistry. 9: 2387-93
Gestwicki JE, Strong LE, Kiessling LL. (2000) Visualization of Single Multivalent Receptor-Ligand Complexes by Transmission Electron Microscopy The authors thank Colleen Lavin (UW Madison, Microscopy Resource) and Kim Dickson for experimental support. This work was supported in part by the NIH (GM 55984). J.E.G. acknowledges the NIH Biotechnology Training Grant for support (T32GM08349). L.E.S. was supported by an NIH predoctoral fellowship (GM 18750). Angewandte Chemie (International Ed. in English). 39: 4567-4570
Kiessling LL, Gestwicki JE, Strong LE. (2000) Synthetic multivalent ligands in the exploration of cell-surface interactions. Current Opinion in Chemical Biology. 4: 696-703
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