Peihan Orestes, Ph.D.

Affiliations: 
2009 University of Virginia, Charlottesville, VA 
Area:
t-type calcium channels
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"Peihan Orestes"
Mean distance: 22.17 (cluster 31)
 

Parents

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Slobodan M. Todorovic grad student 2009 UVA
 (Modulation of T-type calcium channels by anesthetics and analgesics.)
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Publications

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Joksimovic SL, Evans JG, McIntire WE, et al. (2020) Glycosylation of Ca3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes. Frontiers in Cellular Neuroscience. 14: 605312
Joksimovic SL, Joksimovic SM, Manzella FM, et al. (2019) Novel neuroactive steroid with hypnotic and T-channel blocking properties exerts effective analgesia in a rodent model of post-surgical pain. British Journal of Pharmacology
Orestes P, Osuru HP, McIntire WE, et al. (2013) Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels. Diabetes. 62: 3828-38
Shcheglovitov A, Vitko I, Lazarenko RM, et al. (2012) Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Ca(v)2.3 calcium channels. The Journal of General Physiology. 139: 219-34
Shcheglovitov A, Vitko I, Lazarenko RM, et al. (2012) Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Ca v2.3 calcium channels Journal of General Physiology. 139: 389
Orestes P, Bojadzic D, Lee J, et al. (2011) Free radical signalling underlies inhibition of CaV3.2 T-type calcium channels by nitrous oxide in the pain pathway. The Journal of Physiology. 589: 135-48
Orestes P, Todorovic SM. (2010) Are neuronal voltage-gated calcium channels valid cellular targets for general anesthetics? Channels (Austin, Tex.). 4: 518-22
Joksovic PM, Choe WJ, Nelson MT, et al. (2010) Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway. Molecular Pharmacology. 77: 87-94
Lee WY, Orestes P, Latham J, et al. (2009) Molecular mechanisms of lipoic acid modulation of T-type calcium channels in pain pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9500-9
Messinger RB, Naik AK, Jagodic MM, et al. (2009) In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy. Pain. 145: 184-95
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