Jeremy D. Heidel, Ph.D.

Affiliations: 
2005 California Institute of Technology, Pasadena, CA 
Area:
Catalysis, Molecular Therapy
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Parents

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Mark E. Davis grad student 2005 Caltech
 (Targeted, systemic non-viral delivery of small interfering RNA in vivo.)
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Publications

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Kumthekar P, Ko CH, Paunesku T, et al. (2021) A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma. Science Translational Medicine. 13
Zuckerman JE, Gritli I, Tolcher A, et al. (2014) Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA. Proceedings of the National Academy of Sciences of the United States of America. 111: 11449-54
Primiano T, Chang B, Heidel JD. (2014) Abstract LB-103: L1CAM-targeted delivery of siRNA using elastin-like polypeptide (ELP) nanoparticles inhibits the growth of human tumors implanted in mice Cancer Research. 74
Heidel JD, Schluep T. (2012) Cyclodextrin-containing polymers: versatile platforms of drug delivery materials. Journal of Drug Delivery. 2012: 262731
Chang B, Heidel JD, Primiano T. (2012) Abstract 1946: Silencing of EVI1 with siRNA inhibits the growth of ovarian tumor cells Cancer Research. 72: 1946-1946
Heidel JD. (2011) In vivo transfection using cyclodextrin-containing polycations. Cold Spring Harbor Protocols. 2011: 1392-3
Heidel JD. (2011) In vitro transfection using cyclodextrin-containing polycations. Cold Spring Harbor Protocols. 2011: 1389-91
Heidel JD. (2011) Cyclodextrin-containing polycations for nucleic acid delivery. Cold Spring Harbor Protocols. 2011: 1319-22
Heidel JD, Davis ME. (2011) Clinical developments in nanotechnology for cancer therapy. Pharmaceutical Research. 28: 187-99
Davis ME, Zuckerman JE, Choi CH, et al. (2010) Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature. 464: 1067-70
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