Matthew J. Hotchko, Ph.D.

Affiliations: 
2007 University of California, San Diego, La Jolla, CA 
Area:
Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics
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"Matthew Hotchko"
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Elizabeth A. Komives grad student 2007 UCSD
 (Automated extraction of backbone deuteration levels from amide hydrogen/deuterium mass spectrometry experiments to understand EX1 protein unfolding and determine protein binding interfaces.)
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Publications

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Anand GS, Hotchko M, Brown SH, et al. (2007) R-subunit isoform specificity in protein kinase A: distinct features of protein interfaces in PKA types I and II by amide H/2H exchange mass spectrometry. Journal of Molecular Biology. 374: 487-99
Weis DD, Wales TE, Engen JR, et al. (2006) Identification and characterization of EX1 kinetics in H/D exchange mass spectrometry by peak width analysis. Journal of the American Society For Mass Spectrometry. 17: 1498-509
Hotchko M, Anand GS, Komives EA, et al. (2006) Automated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments. Protein Science : a Publication of the Protein Society. 15: 583-601
Law D, Hotchko M, Eyck LT. (2005) Progress in computation and amide hydrogen exchange for prediction of protein–protein complexes Proteins. 60: 302-307
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