Christina A. Wilson, Ph.D.
Affiliations: | 2001 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
tau, dementia, neurodegenerationGoogle:
"Christina Wilson"Mean distance: 16.53 (cluster 24) | S | N | B | C | P |
Parents
Sign in to add mentor| Virginia Man-Yee Lee | grad student | 2001 | Penn | |
| (Multiple roles for presenilins demonstrated by characterization of presenilin null cells.) | ||||
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Publications
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| Phiel CJ, Wilson CA, Lee VMY, et al. (2011) Phiel et al. reply Nature. 480: E6 |
| Wilson CA, Murphy DD, Giasson BI, et al. (2004) Degradative organelles containing mislocalized alpha-and beta-synuclein proliferate in presenilin-1 null neurons. The Journal of Cell Biology. 165: 335-46 |
| Crystal AS, Morais VA, Fortna RR, et al. (2004) Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation. Biochemistry. 43: 3555-63 |
| Wilson CA, Doms RW, Lee VM. (2003) Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production. Journal of Neuroscience Research. 74: 361-9 |
| Phiel CJ, Wilson CA, Lee VM, et al. (2003) GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature. 423: 435-9 |
| Giasson BI, Sampathu DM, Wilson CA, et al. (2002) The environmental toxin arsenite induces tau hyperphosphorylation. Biochemistry. 41: 15376-87 |
| Wilson CA, Doms RW, Zheng H, et al. (2002) Presenilins are not required for A beta 42 production in the early secretory pathway. Nature Neuroscience. 5: 849-55 |
| Wilson CA, Doms RW, Lee VM. (1999) Intracellular APP processing and A beta production in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 58: 787-94 |
| Muir JK, Raghupathi R, Saatman KE, et al. (1999) Terminally differentiated human neurons survive and integrate following transplantation into the traumatically injured rat brain. Journal of Neurotrauma. 16: 403-14 |