Stefan O. Ochiana, Ph.D.
Affiliations: | 2013 | Chemistry & Chemical Biology | Northeastern University, Boston, MA, United States |
Area:
Medicinal chemistry, neglected tropical diseasesGoogle:
"Stefan Ochiana"Mean distance: 9.62 | S | N | B | C | P |
Parents
Sign in to add mentor| Michael P. Pollastri | grad student | 2013 | Northeastern University | |
| (Design, synthesis & evaluation of human Aurora kinase and phosphodiesterase inhibitors for anti-trypanosomal drug discovery via target repurposing.) | ||||
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Publications
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| Dunphy MP, Pressl C, Pillarsetty N, et al. (2020) First-in-Human Trial of Epichaperome-Targeted Positron Emission Tomography in Cancer Patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Taldone T, Zatorska D, Ochiana SO, et al. (2016) Radiosynthesis of the iodine-124 labeled Hsp90 inhibitor PU-H71. Journal of Labelled Compounds & Radiopharmaceuticals |
| Kucine N, Marubayashi S, Bhagwat N, et al. (2015) Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias. Blood |
| Kozakov D, Hall DR, Jehle S, et al. (2015) Ligand deconstruction: Why some fragment binding positions are conserved and others are not. Proceedings of the National Academy of Sciences of the United States of America. 112: E2585-94 |
| Patel HJ, Patel PD, Ochiana SO, et al. (2015) Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94. Journal of Medicinal Chemistry. 58: 3922-43 |
| Ochiana SO, Bland ND, Settimo L, et al. (2015) Repurposing human PDE4 inhibitors for neglected tropical diseases. Evaluation of analogs of the human PDE4 inhibitor GSK-256066 as inhibitors of PDEB1 of Trypanosoma brucei. Chemical Biology & Drug Design. 85: 549-64 |
| Ochiana SO, Taldone T, Patel HJ, et al. (2015) Abstract 2831: Development of selective GRP94 inhibitors for the treatment of cancer Cancer Research. 75: 2831-2831 |
| Rodina AA, Taldone T, Kang Y, et al. (2015) Abstract 1733: Development of chemical tools to study the endogenous Hsp70 interactome in malignant cells Cancer Research. 75: 1733-1733 |
| Kozakov D, Hall DR, Jehle S, et al. (2015) Correction for "Ligand deconstruction: Why some fragment binding positions are conserved and others are not," Proceedings of the National Academy of Sciences of the United States of America. 112: E3749 |
| Taldone T, Ochiana SO, Patel PD, et al. (2014) Selective targeting of the stress chaperome as a therapeutic strategy. Trends in Pharmacological Sciences. 35: 592-603 |