Christopher P. Vellano, Ph.D.

Affiliations: 
2012 Biological and Biomedical Sciences Emory University, Atlanta, GA 
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"Christopher Vellano"
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John Raymond Hepler grad student 2012 Emory
 (Regulator of G Protein Signaling 14 (RGS14) at the Interface of Conventional and Unconventional G Protein Signaling.)
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Vellano CP, Brown NE, Blumer JB, et al. (2013) Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors. The Journal of Biological Chemistry. 288: 3620-31
McCoy KL, Gyoneva S, Vellano CP, et al. (2012) Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop. Cellular Signalling. 24: 1351-60
Vellano CP, Lee SE, Dudek SM, et al. (2011) RGS14 at the interface of hippocampal signaling and synaptic plasticity. Trends in Pharmacological Sciences. 32: 666-74
Vellano CP, Maher EM, Hepler JR, et al. (2011) G protein-coupled receptors and resistance to inhibitors of cholinesterase-8A (Ric-8A) both regulate the regulator of g protein signaling 14 RGS14·Gαi1 complex in live cells. The Journal of Biological Chemistry. 286: 38659-69
Vellano CP, Shu FJ, Ramineni S, et al. (2011) Activation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A. Biochemistry. 50: 752-62
Lee SE, Simons SB, Heldt SA, et al. (2010) RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory. Proceedings of the National Academy of Sciences of the United States of America. 107: 16994-8
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