Karthik Bodhinathan, Ph.D.

Affiliations: 
Neuroscience TG Therapeutics 
Area:
Neurodegeneration, Memory, Neurophysiology, Synaptic Plasticity, Ion channels
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"Karthik Bodhinathan"
Mean distance: 13.47 (cluster 6)
 
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Thomas C. Foster grad student 2005-2010 UF Gainesville
 (Role of redox state in mediating age-related changes in hippocampal synaptic transmission, plasticity and neuronal excitability.)
Paul A. Slesinger post-doc 2010-2013 Salk Institute
Stuart A. Lipton post-doc 2014-2016
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Publications

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Trudler D, Sanz-Blasco S, Eisele YS, et al. (2021) α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Lacin E, Aryal P, Glaaser IW, et al. (2017) Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel. The Journal of General Physiology
Takahashi H, Xia P, Cui J, et al. (2016) Corrigendum: Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease. Scientific Reports. 6: 20750
Takahashi H, Xia P, Cui J, et al. (2015) Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease. Scientific Reports. 5: 14781
Bodhinathan K, Slesinger PA. (2014) Alcohol modulation of G-protein-gated inwardly rectifying potassium channels: from binding to therapeutics. Frontiers in Physiology. 5: 76
Bodhinathan K, Slesinger PA. (2013) Molecular mechanism underlying ethanol activation of G-protein-gated inwardly rectifying potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 18309-14
Balana B, Bahima L, Bodhinathan K, et al. (2013) Ras-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channels. Plos One. 8: e59800
Bodhinathan K, Slesinger PA. (2013) Dissecting Gating Rules of GIRK Channels: Role of PIP2 in Ethanol-Dependent Activation Biophysical Journal. 104: 130a
Wu K, Li S, Bodhinathan K, et al. (2012) Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology. Neurobiology of Learning and Memory. 97: 69-80
Bodhinathan K, Slesinger PA. (2012) Engineering the Alcohol Pocket to Create a Chemically-Activated GIRK Channel Biophysical Journal. 102: 537a
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