Kate K. O'Toole, Ph.D.

Affiliations: 
Tufts University, Boston 
Area:
GABA(A) receptors
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"Kate O'Toole"
Mean distance: 16.26 (cluster 11)
 
SNBCP

Parents

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Andrew Jenkins grad student 2006-2011 Emory
Jamie L. Maguire post-doc 2011-2014 Tufts Medical School
 (TEACRS FELLOWSHIP)
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Publications

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MacKenzie G, O'Toole KK, Maguire J. (2016) Compromised GABAergic inhibition contributes to tumor-associated epilepsy. Epilepsy Research. 126: 185-196
O'Toole KK, Hooper A, Wakefield S, et al. (2014) Seizure-induced disinhibition of the HPA axis increases seizure susceptibility. Epilepsy Research. 108: 29-43
O'Toole KK, Jenkins A. (2012) The apparent voltage dependence of GABAA receptor activation and modulation is inversely related to channel open probability. Molecular Pharmacology. 81: 189-97
O'Toole KK, Jenkins A. (2011) Discrete M3-M4 intracellular loop subdomains control specific aspects of γ-aminobutyric acid type A receptor function. The Journal of Biological Chemistry. 286: 37990-9
Chen PE, Geballe MT, Katz E, et al. (2008) Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. The Journal of Physiology. 586: 227-45
Richardson JE, Garcia PS, O'Toole KK, et al. (2007) A conserved tyrosine in the beta2 subunit M4 segment is a determinant of gamma-aminobutyric acid type A receptor sensitivity to propofol. Anesthesiology. 107: 412-8
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