Robert L. Rosenberg, PhD

Pharmacology & Physiology Drexel University College of Medicine, Philadelphia, PA, United States 
nicotinic receptors, Na channels, Ca channels, neural regeneration
"Robert Rosenberg"

Moved from University of North Carolina - Chapel Hill in 2009
Moved from Earlham College in 2021

Mean distance: 13.48 (cluster 6)


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Christopher Miller research assistant 1977-1979 Brandeis (Chemistry Tree)
William S. Agnew grad student 1981-1985 Yale School of Medicine (Chemistry Tree)
Richard W. Tsien post-doc 1985-1988 Yale School of Medicine


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Rafiq Huda research assistant 2006-2006 Northwestern
Jennifer See research assistant 2007-2009 Earlham College
Patricia Koplas grad student 1988-1995 UNC Chapel Hill
Claire Townsend grad student 1989-1995 UNC Chapel Hill
Aaron Kitzmiller grad student 1991-1998 UNC Chapel Hill
Jianyong Chen grad student 2001 UNC Chapel Hill
Lisa Lyford grad student 1991-2003 UNC Chapel Hill
Donnie Eddins grad student 1997-2004 UNC Chapel Hill
Rebekah Corlew grad student 2009 UNC Chapel Hill
Sean C. Barron grad student 2005-2010 UNC Chapel Hill
Julie Haack post-doc 1992-1994 UNC Chapel Hill (Chemistry Tree)
James T. McLaughlin research scientist 2001-2009 UNC Chapel Hill
BETA: Related publications


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Barron SC, McLaughlin JT, See JA, et al. (2009) An allosteric modulator of alpha7 nicotinic receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), causes conformational changes in the extracellular ligand binding domain similar to those caused by acetylcholine. Molecular Pharmacology. 76: 253-63
McLaughlin JT, Barron SC, See JA, et al. (2009) Conformational changes in alpha 7 acetylcholine receptors underlying allosteric modulation by divalent cations. Bmc Pharmacology. 9: 1
Barron SC, Temple BR, See JA, et al. (2009) Homology models of the alpha7 acetylcholine receptor based upon bacterial receptors: Comparison of experimental and in silico derived data Biochemical Pharmacology. 78: 907-908
McLaughlin JT, Fu J, Rosenberg RL. (2007) Agonist-driven conformational changes in the inner beta-sheet of alpha7 nicotinic receptors. Molecular Pharmacology. 71: 1312-8
McLaughlin JT, Fu J, Sproul AD, et al. (2006) Role of the outer beta-sheet in divalent cation modulation of alpha7 nicotinic receptors. Molecular Pharmacology. 70: 16-22
Lyford LK, Sproul AD, Eddins D, et al. (2003) Agonist-induced conformational changes in the extracellular domain of alpha 7 nicotinic acetylcholine receptors. Molecular Pharmacology. 64: 650-8
Lyford LK, Rosenberg RL. (2003) Chapter 13 Reconstitution in planar lipid bilayers of ion channels synthesized in ovo and in vitro Membrane Science and Technology. 7: 391-412
Eddins D, Sproul AD, Lyford LK, et al. (2002) Glutamate 172, essential for modulation of L247T alpha7 ACh receptors by Ca2+, lines the extracellular vestibule. American Journal of Physiology. Cell Physiology. 283: C1454-60
Eddins D, Lyford LK, Lee JW, et al. (2002) Permeant but not impermeant divalent cations enhance activation of nondesensitizing alpha(7) nicotinic receptors. American Journal of Physiology. Cell Physiology. 282: C796-804
Lyford LK, Lee JW, Rosenberg RL. (2002) Low-affinity Ca(2+) and Ba(2+) binding sites in the pore of alpha7 nicotinic acetylcholine receptors. Biochimica Et Biophysica Acta. 1559: 69-78
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