Heather R. Pelzel, Ph.D.

Affiliations: 
2010 University of Wisconsin, Madison, Madison, WI 
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Robert W. Nickells grad student 2010 UW Madison
 (Gene silencing in apoptotic retinal ganglion cells is associated with promoter histone deacetylation and nuclear translocation of HDAC3.)
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Schmitt HM, Fehrman RL, Maes ME, et al. (2021) Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression. Investigative Ophthalmology & Visual Science. 62: 14
Nickells RW, Pelzel HR. (2015) Tools and resources for analyzing gene expression changes in glaucomatous neurodegeneration. Experimental Eye Research
Schmitt HM, Pelzel HR, Schlamp CL, et al. (2014) Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury. Molecular Neurodegeneration. 9: 39
Pelzel HR, Schlamp CL, Waclawski M, et al. (2012) Silencing of Fem1cR3 gene expression in the DBA/2J mouse precedes retinal ganglion cell death and is associated with histone deacetylase activity. Investigative Ophthalmology & Visual Science. 53: 1428-35
Pelzel HR, Nickells RW. (2011) A role for epigenetic changes in the development of retinal neurodegenerative conditions. Journal of Ocular Biology, Diseases, and Informatics. 4: 104-10
Pelzel HR, Schlamp CL, Nickells RW. (2010) Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis. Bmc Neuroscience. 11: 62
Pelzel HR, Schlamp CL, Poulsen GL, et al. (2006) Decrease of cone opsin mRNA in experimental ocular hypertension. Molecular Vision. 12: 1272-82
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