Leslie Thompson

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Huntington's Disease
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"Leslie Thompson"
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Children

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Erica Rockabrand grad student 2006 UC Irvine
Jacqueline H. Gire grad student 2010 UC Irvine
Emily J. Mitchell grad student 2011 UC Irvine
Tamara A. Kashiwada grad student 2012 UC Irvine
Sarah J. Hernandez post-doc 2015- (FlyTree)
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Publications

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Reyes-Ortiz AM, Abud EM, Burns MS, et al. (2022) Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits. Iscience. 26: 105732
Hernandez SJ, Lim RG, Onur T, et al. (2022) An altered extracellular matrix-integrin interface contributes to Huntington's disease-associated CNS dysfunction in glial and vascular cells. Human Molecular Genetics
Hernandez SJ, Fote G, Reyes-Ortiz AM, et al. (2021) Cooperation of cell adhesion and autophagy in the brain: Functional roles in development and neurodegenerative disease. Matrix Biology Plus. 12: 100089
Smith-Geater C, Hernandez SJ, Lim RG, et al. (2020) Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation. Stem Cell Reports
Ochaba J, Fote G, Kachemov M, et al. (2019) IKKβ slows Huntington's disease progression in R6/1 mice. Proceedings of the National Academy of Sciences of the United States of America
Morozko EL, Ochaba J, Hernandez SJ, et al. (2018) Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice. Journal of Huntington's Disease
Geater C, Hernandez S, Thompson L, et al. (2018) Cellular Models: HD Patient-Derived Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1780: 41-73
Wang B, Zeng L, Merillat SA, et al. (2017) The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin. Neurobiology of Disease
Quinti L, Dayalan Naidu S, Träger U, et al. (2017) KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients. Proceedings of the National Academy of Sciences of the United States of America
Salazar L, Kashiwada T, Krejci P, et al. (2014) Fibroblast growth factor receptor 3 interacts with and activates TGFβ-activated kinase 1 tyrosine phosphorylation and NFκB signaling in multiple myeloma and bladder cancer. Plos One. 9: e86470
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