Damian G. Wheeler, Ph.D.

2018- Translucence Biosystems, Inc 
Signaling-Genomics-Plasticity-Drug Discovery
"Damian G Wheeler"
Mean distance: 13.25 (cluster 36)


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Ellis Cooper grad student 1994-2002 McGill
Richard W. Tsien post-doc 2002-2009 Stanford
Marco Peters research scientist 2009-2018 Dart Neuroscience
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Baumgärtel K, Green A, Hornberger D, et al. (2018) PDE4D regulates Spine Plasticity and Memory in the Retrosplenial Cortex. Scientific Reports. 8: 3895
Nonaka M, Fitzpatrick R, Lapira J, et al. (2017) Everyday memory: towards a translationally effective method of modeling the encoding, forgetting and enhancement of memory. The European Journal of Neuroscience
Peters M, Bletsch M, Stanley J, et al. (2014) The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2938-48
Wheeler DG, Groth RD, Ma H, et al. (2012) Ca(V)1 and Ca(V)2 channels engage distinct modes of Ca(2+) signaling to control CREB-dependent gene expression. Cell. 149: 1112-24
Ma H, Groth RD, Wheeler DG, et al. (2011) Excitation-transcription coupling in sympathetic neurons and the molecular mechanism of its initiation. Neuroscience Research. 70: 2-8
Tsien RW, Wheeler DG, Groth RD, et al. (2010) Excitation-transcription coupling mechanisms engaged by specific calcium channel types Neuroscience Research. 68: e20
Espinosa JS, Wheeler DG, Tsien RW, et al. (2009) Uncoupling dendrite growth and patterning: single-cell knockout analysis of NMDA receptor 2B. Neuron. 62: 205-17
Wheeler DG, Barrett CF, Groth RD, et al. (2008) CaMKII locally encodes L-type channel activity to signal to nuclear CREB in excitation-transcription coupling. The Journal of Cell Biology. 183: 849-63
Wheeler DG, Barrett CF, Tsien RW. (2006) L-type calcium channel ligands block nicotine-induced signaling to CREB by inhibiting nicotinic receptors. Neuropharmacology. 51: 27-36
Wheeler DG, Cooper E. (2004) Weak synaptic activity induces ongoing signaling to the nucleus that is enhanced by BDNF and suppressed by low-levels of nicotine. Molecular and Cellular Neurosciences. 26: 50-62
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