Xinyuan Wu, Ph.D.

Affiliations: 
2003 Stony Brook University, Stony Brook, NY, United States 
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"Xinyuan Wu"
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Iwao Ojima grad student 2003 SUNY Stony Brook
 (Design, synthesis and biological evaluation of tumor -targeting taxane-based anticancer agents and MDR modulators.)
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Publications

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Dong M, Wang HY, Zhao XX, et al. (2016) Expression and prognostic roles of PIK3CA, JAK2, PD-L1 and PD-L2 in EBV-associated gastric carcinoma. Human Pathology
Pepe A, Sun L, Zanardi I, et al. (2009) Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin. Bioorganic & Medicinal Chemistry Letters. 19: 3300-4
Pepe A, Sun L, Zanardi I, et al. (2009) ChemInform Abstract: Novel C-Seco-Taxoids Possessing High Potency Against Paclitaxel-Resistant Cancer Cell Lines Overexpressing Class III β-Tubulin. Cheminform. 40
Kuznetsova L, Chen J, Sun L, et al. (2006) Syntheses and evaluation of novel fatty acid-second-generation taxoid conjugates as promising anticancer agents. Bioorganic & Medicinal Chemistry Letters. 16: 974-7
Ojima I, Borella CP, Wu X, et al. (2005) Design, synthesis and structure-activity relationships of novel taxane-based multidrug resistance reversal agents. Journal of Medicinal Chemistry. 48: 2218-28
Miller ML, Roller EE, Wu X, et al. (2004) Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies. Bioorganic & Medicinal Chemistry Letters. 14: 4079-82
Wu X, Ojima I. (2004) Tumor specific novel taxoid-monoclonal antibody conjugates. Current Medicinal Chemistry. 11: 429-38
Kuznetsova L, Ungureanu IM, Pepe A, et al. (2004) Trifluoromethyl- and difluoromethyl-β-lactams as useful building blocks for the synthesis of fluorinated amino acids, dipeptides, and fluoro-taxoids Journal of Fluorine Chemistry. 125: 487-500
Ojima I, Geng X, Wu X, et al. (2002) Tumor-specific novel taxoid-monoclonal antibody conjugates. Journal of Medicinal Chemistry. 45: 5620-3
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