Danielle M. Turley, Ph.D.

Affiliations: 
2007 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Molecular Neuroscience, Neurobiology of Disease, Neuroimmunology
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"Danielle Turley"
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Stephen Miller grad student 2007 Northwestern
 (Dual mechanisms for antigen-specific peripheral tolerance induction as a therapy for experimental autoimmune encephalomyelitis.)
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Publications

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Getts DR, Turley DM, Smith CE, et al. (2011) Tolerance induced by apoptotic antigen-coupled leukocytes is induced by PD-L1+ and IL-10-producing splenic macrophages and maintained by T regulatory cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 2405-17
Turley DM, Miller SD. (2010) Prospects for antigen-specific tolerance based therapies for the treatment of multiple sclerosis. Results and Problems in Cell Differentiation. 51: 217-35
Podojil JR, Turley DM, Miller SD. (2008) Therapeutic blockade of T-cell antigen receptor signal transduction and costimulation in autoimmune disease. Advances in Experimental Medicine and Biology. 640: 234-51
Miller S, Kohm A, Prasad S, et al. (2008) OR.19. An Antigen-specific Approach to the Treatment of Type 1 Diabetes and Islet Transplantation Clinical Immunology. 127
Miller SD, Turley DM, Podojil JR. (2007) Antigen-specific tolerance strategies for the prevention and treatment of autoimmune disease. Nature Reviews. Immunology. 7: 665-77
Turley DM, Miller SD. (2007) Peripheral tolerance induction using ethylenecarbodiimide-fixed APCs uses both direct and indirect mechanisms of antigen presentation for prevention of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 178: 2212-20
Kohm AP, Turley DM, Miller SD. (2005) Targeting the TCR: T-cell receptor and peptide-specific tolerance-based strategies for restoring self-tolerance in CNS autoimmune disease. International Reviews of Immunology. 24: 361-92
Minter LM, Turley DM, Das P, et al. (2005) Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nature Immunology. 6: 680-8
Eagar TN, Turley DM, Padilla J, et al. (2004) CTLA-4 regulates expansion and differentiation of Th1 cells following induction of peripheral T cell tolerance. Journal of Immunology (Baltimore, Md. : 1950). 172: 7442-50
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