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Joanne Clark

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Neurodegeneration, Aging, Parkinson's Disease, Oxidative Stress
Google:
"Joanne Clark"
Mean distance: 18.28 (cluster 28)
 
Cross-listing: Neuropathology Tree

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Parents

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Kay Elizabeth Davies grad student 2002-2006 Oxford
David Keith Simon post-doc 2006- Harvard

Children

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Publications

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Dai Y, Clark J, Zheng K, et al. (2014) Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young POLG mutator mice. Neurotoxicology and Teratology. 46: 62-7
Dai Y, Zheng K, Clark J, et al. (2014) Rapamycin drives selection against a pathogenic heteroplasmic mitochondrial DNA mutation. Human Molecular Genetics. 23: 637-47
Dai Y, Kiselak T, Clark J, et al. (2013) Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice. Mitochondrion. 13: 282-91
Clark J, Silvaggi JM, Kiselak T, et al. (2012) Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf. Plos One. 7: e48925
Clark J, Dai Y, Simon DK. (2011) Do somatic mitochondrial DNA mutations contribute to Parkinson's disease? Parkinson's Disease. 2011: 659694
Clark J, Reddy S, Zheng K, et al. (2011) Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease. Bmc Medical Genetics. 12: 69
Clark J, Clore EL, Zheng K, et al. (2010) Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice. Plos One. 5: e12333
Clark J, Simon DK. (2009) Transcribe to survive: transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease. Antioxidants & Redox Signaling. 11: 509-28
Oliver PL, Bitoun E, Clark J, et al. (2004) Mediation of Af4 protein function in the cerebellum by Siah proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 14901-6
Rocques PJ, Clark J, Ball S, et al. (1995) The human SB1.8 gene (DXS423E) encodes a putative chromosome segregation protein conserved in lower eukaryotes and prokaryotes. Human Molecular Genetics. 4: 243-9
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